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Myozyme : EPAR - Scientific Discussion
Myozyme : EPAR - Scientific Discussion

... Pompe disease is a rare autosomal recessive disease caused by the deficiency of acid α-glucosidase (GAA), which degrades lysosomal glycogen through the hydrolysis of α-1,4- and α-1,6- glycosidic linkages. Other names for Pompe disease include Glycogen Storage Disease type II, Acid Maltase Deficiency ...
Document
Document

... receptor agonist used for the relief of bronchospasm in conditions such as asthma and COPD.Salbutamol sulphate is usually given by the inhaled route for direct effect on bronchial smooth muscle. This is usually achieved through a metered dose inhaler (MDI), nebuliser or other proprietary delivery de ...
Baclofen PI
Baclofen PI

... affected by sedation and decreased alertness caused by baclofen. Patients should, therefore, exercise due caution when driving a vehicle or operating machinery. Carcinogenicity/Mutagenicity. A two year carcinogenicity study in rats found no evidence that baclofen had carcinogenic potential at oral d ...
Binocular Indirect Ophthalmoscopy Procedures In Co
Binocular Indirect Ophthalmoscopy Procedures In Co

... This chapter deals with the use of Binocular Indirect Ophthalmoscopy (BIO) lenses for the assessment of the retinal effects of systemic disease, with special reference to those diseases involved in shared care or co-management programmes. Much of the eye examination routine will be similar for a pat ...
Clinical Practice Guidelines for Oral Management in Sjögren`s
Clinical Practice Guidelines for Oral Management in Sjögren`s

... Guidelines for Caries Prevention in Sjögren’s to ensure quality and consistency of care for the assessment and management of patients. The SSF Clinical Practice Guidelines for Caries Prevention in Sjögren’s patients will help dentists, oral medicine specialists and Sjögren’s disease patients determi ...
SELEGILINE
SELEGILINE

... administering oral selegiline 5–10 mg/day in Parkinson’s disease • At doses above 10 mg/day (oral), selegiline may become nonselective and inhibit both MAO-A and MAO-B • At doses above 30 mg/day (oral), selegiline may have antidepressant properties • Patients receiving high oral doses may need to be ...
Modified thromboelastography evaluation of platelet dysfunction in
Modified thromboelastography evaluation of platelet dysfunction in

... Because of the high negative impact associated with reexploration procedures resulting from postoperative bleeding during the perioperative period, the authors chose this event rate as the study’s primary outcome. Patients were excluded from the study if a clear source of surgical bleeding was found ...
Advanced Thoracic Goals and Objectives - IU Anesthesia
Advanced Thoracic Goals and Objectives - IU Anesthesia

... Regarding rotational specific issues please contact the individuals listed above. When rotating on either CV or Neuro rotations at Methodist, Dr. Michael Miller has agreed to oversee issues associated with general resident related education matters. Core Competencies: The six core competencies are u ...
Birmingham Children’s Hospital NHS Foundation Trust Quality Account 2012-13  1
Birmingham Children’s Hospital NHS Foundation Trust Quality Account 2012-13 1

... that needs or chooses to come to BCH without any delays; making things safer than ever before and improving health outcomes for the diverse range of children and young people that we see every day. It is important that we focus our resources on making improvements where they are needed most, so we c ...
PDF - British Journal of Medical Practitioners
PDF - British Journal of Medical Practitioners

... males and 47 percent in women. The common modifiable risk factors identified were unhealthy diet, physical inactivity and tobacco use, leading to raised blood pressure and blood glucose, abnormal blood lipids and becoming overweight.1 The WHO MONICA Project - an international collaboration of resear ...
view article pdf
view article pdf

... attribution. Other reproduction is prohibited without written permission from ISMP. Report actual and potential medication errors to the Medication Errors Reporting Program (MERP) via the Web at www.ismp.org or by calling ...
File - Student Portal
File - Student Portal

... What should a pharmacy technician do when a parent is struggling to determine the best dose of an OTC medication for a pediatric patient? Ask the pharmacist to determine the child’s dose for the caretaker if the dose information is not provided. ...
Harmful Interactions: Mixing Alcohol with Medicines
Harmful Interactions: Mixing Alcohol with Medicines

... ou’ve probably seen this warning on medicines you’ve taken. The danger is real. Mixing alcohol with certain medications can cause nausea and vomiting, headaches, drowsiness, fainting, or loss of coordination. It also can put you at risk for internal bleeding, heart problems, and difficulties in brea ...
Infusion Master
Infusion Master

... and meperidine. Other opioids are preferred over meperidine in elderly or renally compromised patients. If it persists, use a pre-treatment (consider tramadol), consider switching brands of IVIG, or consider administering it differently—long-term infusion or SCIG, for example. • Anaphylactoid reacti ...
The Complications of Transforaminal Lumbar Epidural Steroid
The Complications of Transforaminal Lumbar Epidural Steroid

... transforaminal method now. The complications of this method cause to a serious concern. The complications of this intervention have been reported by either mostly retrospective studies or case reports until now. Prospective studies with large patient series are needed to determine the types and inci ...
Warfarin Initiation Guidelines
Warfarin Initiation Guidelines

... These nomograms are useful in outpatients in whom INR checks can be performed with less frequency. Initiation strategies using 10 mg warfarin doses have been tested in randomized trials and are supported in published guidelines. Practitioners experienced in anticoagulation initiation may choose to u ...
Does levetircetam decrease of the rubral tremor in patients with
Does levetircetam decrease of the rubral tremor in patients with

... Background: One of the frequent symptoms of Multiple Sclerosis (MS) is tremor which can severely cause disability. Treatment of tremor in MS patients is still very challenging to manage. In this study, we sought to determine the efficacy of Levetiracetam on treatment of MS‑related tremor. Materials ...
Wegener`s Handbook - St. James`s Hospital
Wegener`s Handbook - St. James`s Hospital

... early as possible and to continue on treatment as advised by your doctor. Long-term follow up is essential and so it is important that the patient remains in regular contact with their doctor. In this way, complications, such as raised blood pressure can be diagnosed and treated early. Research into ...
A HIV T R
A HIV T R

... taking reached 80%, one could label the patient as “adherent.” 4,5 However, recent evidence suggests that an 80% level with HAART adherence may be inadequate to prevent the development of antiretroviral drug resistance.5,21 This is significant in light of preliminary studies that suggest most indivi ...
Review: New oral anticoagulants reduced stroke and systemic
Review: New oral anticoagulants reduced stroke and systemic

... renal dysfunction. Apixaban is safe for patients with moderate renal disease. Patients with creatinine clearance <30 mL/min should use warfarin. Once-daily rivaroxaban is more convenient than twice-daily dabigatran or apixaban. Patients on warfarin with good control of international normalized ratio ...
Management of oral drug therapy in elderly patients with dysphagia
Management of oral drug therapy in elderly patients with dysphagia

... severity of dysphagia and incidence of malnutrition 35 36. In a recent study in older patients with dysphagia the prevalence of malnutrition (36.8%) and risk of malnutrition (55.3%) was significantly higher compared older patients without dysphagia 37. A recent resolution of the Council of Europe on ...
AN OPEN STUDY TO ASSESS THE SAFETY AND TOLERABILITY
AN OPEN STUDY TO ASSESS THE SAFETY AND TOLERABILITY

... 325 mg) were supplied as rescue medication (dose limited to eight tablets per day) for pain relief when appropriate, during washout and treatment periods. A second screening visit was conducted no less than 4 days after the first screening visit and patients were not included in the study if the cal ...
Antipsychotics - 2011
Antipsychotics - 2011

... Agranulocytosis: Because of a significant risk of agranulocytosis, a potentially life-threatening adverse reaction, reserve clozapine for use in the treatment of severely ill schizophrenic patients who fail to show an acceptable response to adequate courses of standard antipsychotic drug treatment b ...
Guidelines for antiretroviral therapy in adults
Guidelines for antiretroviral therapy in adults

... and the mortality risk associated with intracranial cryptococcal IRIS need to be balanced, and published studies have shown conflicting results.13,14 The Cryptococcal Optimal ART Timing (COAT) trial was recently stopped early by the Data and Safety Monitoring Board because of excess mortality in pat ...
HIGHLIGHTS OF PRESCRIBING INFORMATION These
HIGHLIGHTS OF PRESCRIBING INFORMATION These

... appears to be highest among the elderly, especially elderly women, but it is not possible to predict which patients are likely to develop the syndrome. Whether antipsychotic drugs differ in their potential to cause tardive dyskinesia is unknown. The risk of tardive dyskinesia and the likelihood that ...
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Adherence (medicine)

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