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Recent Advances in Hypertension
Recent Advances in Hypertension

... observed in low-fit individuals (peak MET level 6.1–8.0) compared with the least-fit (peak MET level ≤6.0), suggesting that relatively low levels of cardiorespiratory fitness are necessary for exercise-related health benefits. Risk reduction was progressively greater in moderate-fit (58%) and high-f ...
Improving usual care after sudden death in the young with focus on
Improving usual care after sudden death in the young with focus on

... age has been estimated at 1–2 per 100 000 person-years.1,2 Inherited cardiac diseases, particularly premature coronary heart disease (CHD) and inherited cardiomyopathies, are important causes of SCD.1 – 3 In cases that remain unexplained after autopsy [so-called sudden arrhythmic death syndrome (SAD ...
AACE Guidelines
AACE Guidelines

... Program; QALY = quality-adjusted life-year; VLDL-C = very low-density lipoprotein cholesterol 1. INTRODUCTION Each year, an estimated 785 000 Americans will have a new coronary artery disease (CAD) event, and approximately 470 000 will have a recurrent attack. CAD caused approximately 1 of every 6 d ...
PATHOPHYSIOLOGY OF CONGENITAL HEART DISEASE
PATHOPHYSIOLOGY OF CONGENITAL HEART DISEASE

... Only 30% are isolated Often with TETRALOGY of FALLOT 90% involve the membranous septum If muscular septum is involved, likely to have multiple holes SMALL ones often close spontaneously LARGE ones progress to pulmonary hypertension. ...
Sudden Cardiac Arrest Information Sheet FAQs and
Sudden Cardiac Arrest Information Sheet FAQs and

... SCA is caused by several structural and electrical diseases of the heart. These conditions predispose an individual to have an abnormal rhythm that can be fatal if not treated within a few minutes. Most conditions responsible for SCA in children are inherited, which means the tendency to have these ...
Sudden Cardiac Arrest (SCA) Information for Parents and Student
Sudden Cardiac Arrest (SCA) Information for Parents and Student

... SCA is caused by several structural and electrical diseases of the heart. These conditions predispose an individual to have an abnormal rhythm that can be fatal if not treated within a few minutes. Most conditions responsible for SCA in children are inherited, which means the tendency to have these ...
Recovery Heart Rate Response in Sedentary and Physically Active
Recovery Heart Rate Response in Sedentary and Physically Active

... primarily to an increase in the parasympathetic activity with a minor decrease in sympathetic discharge[13, 14]. The physically active group showed a significantly faster decrease in heart rate to pre exercise value than the age matched sedentary controls. HR recovery after exercise depends on sever ...
Echocardiography in heart failure – a guide for general practice
Echocardiography in heart failure – a guide for general practice

... have had an echocardiogram have a better outcome than those who have not, presumably due to more appropriate evidence based management.2 This article will discuss why assessment of cardiac structure and function is critical in evaluating heart failure, the specific information gained from an echocar ...
Hypertension, hypertensive heart disease and perioperative cardiac
Hypertension, hypertensive heart disease and perioperative cardiac

... A number of studies examining stroke after carotid endarterectomy have been excluded, as it is argued that these studies examined a particular complication in an exceptional population, and the ®ndings from such studies may not generalize to patients undergoing other types of surgery. The main focus ...
Pompe Disease (Glycogen	Storage	Disease,	Type	II; Acid	Maltase	Deficiency) The Physician’s Guide to
Pompe Disease (Glycogen Storage Disease, Type II; Acid Maltase Deficiency) The Physician’s Guide to

... The clinical spectrum of Pompe disease is continuous and broad. In the severe, infantile onset cases, signs and symptoms usually present within the first months of life. In many late-onset patients, symptoms may not develop (or be brought to clinical attention) for several years or decades. Initial ...
August - North American - Congenital Cardiology Today
August - North American - Congenital Cardiology Today

... education, they also serve as new tools for scientific studies of cardiogenesis and congenital heart diseases. During cardiogenesis, sizes of the heart’s chambers change significantly, but few studies have attempted to quantify it. In our work we reconstructed and analyzed chicken hearts at stage HH ...
Comorbidity and Ventricular and Vascular Structure and Function in
Comorbidity and Ventricular and Vascular Structure and Function in

... Background—Patients with heart failure and preserved ejection fraction (HFpEF) display increased adiposity and multiple comorbidities, factors that in themselves may influence cardiovascular structure and function. This has sparked debate as to whether HFpEF represents a distinct disease or an amalg ...
Exercise-Induced Left Ventricular Systolic Dysfunction in Women
Exercise-Induced Left Ventricular Systolic Dysfunction in Women

... persons at risk to optimize the timing of therapeutic interventions aimed at avoiding overt end-stage heart failure. Screening may consist of routine clinical examination only or may also include electrocardiography and possibly routine two-dimensional echocardiography. However, this approach can su ...
Oxidative Stress and Salvia miltiorrhiza in Aging
Oxidative Stress and Salvia miltiorrhiza in Aging

... [2]. CVDs are the leading form of noncommunicable diseases [2]. In 2012 and 2013, 17.3 million deaths worldwide resulted from CVDs [3]. Among these deaths, coronary artery disease and stroke contributed most to the total global burden of ...
Acute myocardial infarction due to left anterior descending coronary
Acute myocardial infarction due to left anterior descending coronary

... an integral part of initial trauma evaluation, even in younger population. Once the patient is hemodynamically stabilized, this readily available and simple test plays an important role in identifying myocardial contusion (manifested as conduction abnormalities and ST or T wave changes), cardiac arr ...
Acute myocardial infarction due to left anterior descending coronary
Acute myocardial infarction due to left anterior descending coronary

... an integral part of initial trauma evaluation, even in younger population. Once the patient is hemodynamically stabilized, this readily available and simple test plays an important role in identifying myocardial contusion (manifested as conduction abnormalities and ST or T wave changes), cardiac arr ...
Fish oil reduces heart rate and oxygen
Fish oil reduces heart rate and oxygen

... Following FO supplementation there were significant increases in membrane fatty acid levels of DHA (22:6n-3), the sum of PUFA and the sum of omega-3 PUFA (p<0.05) (Table 2). The FO supplementation produced no change in the polyunsaturated/saturated (P:S) ratio (Control pre: 1.05; post: 1.06; FO pre: ...
Appendix I - Cairdtech
Appendix I - Cairdtech

... Heart rate turbulence (HRT) is a newly established risk predictor which characterizes the early acceleration (HRT Onset) and late deceleration (HRT Slope)of sinus rhythm following ventricular premature complexes (VPCs) (left figure). HRT has shown to be a strong mortality predictor after myocardial ...
Clinicopathological Conference A 37-Year
Clinicopathological Conference A 37-Year

... On admission, she denied any other major complaints. She had not had any recent fever or chills, melena or hematemesis, abdominal pain, headache, or back pain. She had not had any chest pains in the past. The patient denied any significant past medical problems and was on no chronic medication at th ...
Medical treatment of stable angina: A tailored therapeutic approach
Medical treatment of stable angina: A tailored therapeutic approach

... with STEMI who were treated with primary PCI and had a preserved ejection fraction [23]. In a post-hoc analysis of the CHARISMA trial, the use of beta-blockers in patients with prior MI but no heart failure was associated with a lower composite cardiovascular outcome driven by lower risk of recurren ...
Prevention of sudden cardiac death in
Prevention of sudden cardiac death in

... and small vessel disease.1 w3 Sudden cardiac death (SCD), heart failure, and thromboembolism are the main causes of death.3 Early studies of small HCM cohorts from tertiary referral centres reported cardiovascular mortality rates of ∼6%/year, but later less selected studies demonstrated a more favou ...
Natriuretic peptide vs. clinical information for diagnosis of left
Natriuretic peptide vs. clinical information for diagnosis of left

... Other variables were entered into the model but were excluded by the stepwise regression: age (dichotomized by the median), sex, BMI>30, diabetes mellitus, hypertension, hyperlipidemia, myocardial infarction, family history of early heart disease, treatment with ACE inhibitors, β blockers, calcium c ...
Student Sourcing
Student Sourcing

... Describe the factors that influence blood pressure and how blood pressure is regulated. Explain how the cardiovascular system responds to changes in the body's conditions. ...
The Advanced Cardiovascular Life Support Guidelines
The Advanced Cardiovascular Life Support Guidelines

... sotalol a poor choice. Amiodarone, 150 mg over 10 minutes, is given. Unfortunately, she does not respond but instead becomes unresponsive, with a blood pressure of 65/35. Synchronized cardioversion at 100 J is attempted because the patient’s rhythm is wide-complex regular. CRITICAL DECISION How have ...
American College of Cardiology Foundation (ACCF) American Heart
American College of Cardiology Foundation (ACCF) American Heart

... • The incidence of coronary heart disease in women lags behind men by 10 years for total coronary heart disease and by 20 years for more serious clinical events such as myocardial infarction and death. • While death rates have fallen from 1968 to the present, coronary heart disease is the largest ki ...
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Cardiovascular disease



Cardiovascular disease (CVD) is a class of diseases that involve the heart or blood vessels. Cardiovascular disease includes coronary artery diseases (CAD) such as angina and myocardial infarction (commonly known as a heart attack). Other CVDs are stroke, hypertensive heart disease, rheumatic heart disease, cardiomyopathy, atrial fibrillation, congenital heart disease, endocarditis, aortic aneurysms, peripheral artery disease and venous thrombosis.The underlying mechanisms vary depending on the disease in question. Coronary artery disease, stroke, and peripheral artery disease involve atherosclerosis. This may be caused by high blood pressure, smoking, diabetes, lack of exercise, obesity, high blood cholesterol, poor diet, and excessive alcohol consumption, among others. High blood pressure results in 13% of CVD deaths, while tobacco results in 9%, diabetes 6%, lack of exercise 6% and obesity 5%. Rheumatic heart disease may follow untreated strep throat.It is estimated that 90% of CVD is preventable. Prevention of atherosclerosis is by decreasing risk factors through: healthy eating, exercise, avoidance of tobacco smoke and limiting alcohol intake. Treating high blood pressure and diabetes is also beneficial. Treating people who have strep throat with antibiotics can decrease the risk of rheumatic heart disease. The effect of the use of aspirin in people who are otherwise healthy is of unclear benefit. The United States Preventive Services Task Force recommends against its use for prevention in women less than 55 and men less than 45 years old; however, in those who are older it is recommends in some individuals. Treatment of those who have CVD improves outcomes.Cardiovascular diseases are the leading cause of death globally. This is true in all areas of the world except Africa. Together they resulted in 17.3 million deaths (31.5%) in 2013 up from 12.3 million (25.8%) in 1990. Deaths, at a given age, from CVD are more common and have been increasing in much of the developing world, while rates have declined in most of the developed world since the 1970s. Coronary artery disease and stroke account for 80% of CVD deaths in males and 75% of CVD deaths in females. Most cardiovascular disease affects older adults. In the United States 11% of people between 20 and 40 have CVD, while 37% between 40 and 60, 71% of people between 60 and 80, and 85% of people over 80 have CVD. The average age of death from coronary artery disease in the developed world is around 80 while it is around 68 in the developing world. Disease onset is typically seven to ten years earlier in men as compared to women.
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