Advances in Cardiovascular Imaging
... disability worldwide.1 The underlying process of atherosclerosis in the coronary vessel wall may progress to stenosis or plaque rupture2,3 often leading to myocardial damage. The evolution of early changes in the vessel wall leading to pathological lesions is conceptualized as a sequential progressi ...
... disability worldwide.1 The underlying process of atherosclerosis in the coronary vessel wall may progress to stenosis or plaque rupture2,3 often leading to myocardial damage. The evolution of early changes in the vessel wall leading to pathological lesions is conceptualized as a sequential progressi ...
PDF - Arteriosclerosis, Thrombosis, and Vascular Biology
... he increase in coronary blood flow (CBF) associated with increased myocardial metabolism is commonly referred to as metabolic vasodilation. Several vasodilator substances produced by the myocardium or from the vascular endothelium have been proposed as mediators of metabolic vasodilation including a ...
... he increase in coronary blood flow (CBF) associated with increased myocardial metabolism is commonly referred to as metabolic vasodilation. Several vasodilator substances produced by the myocardium or from the vascular endothelium have been proposed as mediators of metabolic vasodilation including a ...
Left Main Coronary Artery Stenosis after Aortic Valve Replacement
... The usual clinical picture includes severe angina, ventricular arrhythmias, congestive heart failure and sudden death. It usually appears within the first six months but may occur up to thirty months after the procedure.3-24 The incidence of this complication has been estimated to be less than 3%,6- ...
... The usual clinical picture includes severe angina, ventricular arrhythmias, congestive heart failure and sudden death. It usually appears within the first six months but may occur up to thirty months after the procedure.3-24 The incidence of this complication has been estimated to be less than 3%,6- ...
Dual left anterior descending artery circulation: a rare anomaly of the
... (LAD) artery arises from the left coronary artery (LCA) and courses along the anterior interventricular sulcus (AIVS) until it reaches the apex. Dual LAD circulation is an uncommon coronary anomaly in which there are two LAD arteries. A type 4 dual LAD circulation is an extremely rare variant of a d ...
... (LAD) artery arises from the left coronary artery (LCA) and courses along the anterior interventricular sulcus (AIVS) until it reaches the apex. Dual LAD circulation is an uncommon coronary anomaly in which there are two LAD arteries. A type 4 dual LAD circulation is an extremely rare variant of a d ...
Practice Guideline
... and the American Heart Association (AHA) have jointly produced guidelines in the area of cardiovascular disease since 1980. The ACCF/AHA Task Force on Practice Guidelines (Task Force), charged with developing, updating, and revising practice guidelines for cardiovascular diseases and procedures, dir ...
... and the American Heart Association (AHA) have jointly produced guidelines in the area of cardiovascular disease since 1980. The ACCF/AHA Task Force on Practice Guidelines (Task Force), charged with developing, updating, and revising practice guidelines for cardiovascular diseases and procedures, dir ...
Factors Associated With Major Bleeding Events
... moderate-to-high risk for stroke. Elevated risk was indicated by a history of stroke, transient ischemic attack (TIA), or systemic embolism or at least 2 of the following risk factors: heart failure or a left ventricular ejection fraction 35%; hypertension; age 75 years; or diabetes mellitus. The ...
... moderate-to-high risk for stroke. Elevated risk was indicated by a history of stroke, transient ischemic attack (TIA), or systemic embolism or at least 2 of the following risk factors: heart failure or a left ventricular ejection fraction 35%; hypertension; age 75 years; or diabetes mellitus. The ...
Factors Associated With Major Bleeding Events
... moderate-to-high risk for stroke. Elevated risk was indicated by a history of stroke, transient ischemic attack (TIA), or systemic embolism or at least 2 of the following risk factors: heart failure or a left ventricular ejection fraction 35%; hypertension; age 75 years; or diabetes mellitus. The ...
... moderate-to-high risk for stroke. Elevated risk was indicated by a history of stroke, transient ischemic attack (TIA), or systemic embolism or at least 2 of the following risk factors: heart failure or a left ventricular ejection fraction 35%; hypertension; age 75 years; or diabetes mellitus. The ...
Diet, Hypertension and Salt Toxicity
... their blood pressure will likely go over time. Currently more 90% of Americans can expect to be diagnosed with hypertension during their lifetime. The report also recommends Americans roughly double their current potassium intake up to 4700 mg/day by eating a lot more fruits and vegetables as this h ...
... their blood pressure will likely go over time. Currently more 90% of Americans can expect to be diagnosed with hypertension during their lifetime. The report also recommends Americans roughly double their current potassium intake up to 4700 mg/day by eating a lot more fruits and vegetables as this h ...
Artifacts in ECG-Synchronized MDCT Coronary Angiography
... OBJECTIVE. In MDCT coronary angiography, image artifacts are the major cause of false-positive and false-negative interpretations regarding the presence of coronary artery stenoses. Hence, it is important that observers reporting these investigations are aware of the potential presence of image arti ...
... OBJECTIVE. In MDCT coronary angiography, image artifacts are the major cause of false-positive and false-negative interpretations regarding the presence of coronary artery stenoses. Hence, it is important that observers reporting these investigations are aware of the potential presence of image arti ...
Anastomoses Between Bronchial and Coronary Circulation in a
... the pedicled mammary artery or an aortic button, as occurs in lung transplantation cases.21,22 Moreover, in similar cases, but without ischaemic heart disease, it seems that the coronary arteries can contribute to the bronchial circulation because of the reverse distribution. We also highlight the i ...
... the pedicled mammary artery or an aortic button, as occurs in lung transplantation cases.21,22 Moreover, in similar cases, but without ischaemic heart disease, it seems that the coronary arteries can contribute to the bronchial circulation because of the reverse distribution. We also highlight the i ...
The Heart - Pearson Higher Education
... ur ceaselessly beating heart has intrigued people for centuries. The ancient Greeks believed the heart was the seat of intelligence. Others thought it was the source of emotions. While these ideas have proved false, we do know that emotions affect heart rate. When your heart pounds or skips a beat, ...
... ur ceaselessly beating heart has intrigued people for centuries. The ancient Greeks believed the heart was the seat of intelligence. Others thought it was the source of emotions. While these ideas have proved false, we do know that emotions affect heart rate. When your heart pounds or skips a beat, ...
PDF
... Epicardial adipose tissue (EAT) is the fat depot surrounding the heart and confined within the pericardial sac. It accounts for approximately 20% of total heart weight and covers 80% of the cardiac surfaces, mostly in the grooved segments along the paths of coronary arteries. To clearly delineate th ...
... Epicardial adipose tissue (EAT) is the fat depot surrounding the heart and confined within the pericardial sac. It accounts for approximately 20% of total heart weight and covers 80% of the cardiac surfaces, mostly in the grooved segments along the paths of coronary arteries. To clearly delineate th ...
Role of ST2 in Non–ST-Elevation Acute Coronary Syndrome in the
... conditions and cardiovascular disease (1–5 ). Originally identified in 1989 as an orphan receptor, the ST2 ligand was discovered to be IL-33 in 2005; its downstream effects include activation of T-helper type 2 (Th2) cells and production of Th2-associated cytokines (6, 7 ). A role of ST2 in cardiova ...
... conditions and cardiovascular disease (1–5 ). Originally identified in 1989 as an orphan receptor, the ST2 ligand was discovered to be IL-33 in 2005; its downstream effects include activation of T-helper type 2 (Th2) cells and production of Th2-associated cytokines (6, 7 ). A role of ST2 in cardiova ...
Syncope - Royal College of Emergency Medicine
... occurring whilst supine or during exercise (note syncope occurring post exercise is almost always a simple vaso-vagal), new dyspnoea, evidence of cardiac failure, chest pain and ECG evidence of any of the following: second degree or complete heart block (refer to Bart’s electrophysiologists), abnorm ...
... occurring whilst supine or during exercise (note syncope occurring post exercise is almost always a simple vaso-vagal), new dyspnoea, evidence of cardiac failure, chest pain and ECG evidence of any of the following: second degree or complete heart block (refer to Bart’s electrophysiologists), abnorm ...
Cardiovascular and sympathetic responses and reflex changes
... 100 ⫾ 4 mmHg, respectively, n ⫽ 6) were not significantly different. Figure 1 compares the dose–effect relationships of MDMA and d-amphetamine for HR and MAP in conscious rats. MDMA (0.01–3.0 mg/kg, i.v.) elicited significant, F(4, 20) ⫽ 10.7, p ⬍ 0.001, dose-dependent increases in MAP (Fig. 1A). Am ...
... 100 ⫾ 4 mmHg, respectively, n ⫽ 6) were not significantly different. Figure 1 compares the dose–effect relationships of MDMA and d-amphetamine for HR and MAP in conscious rats. MDMA (0.01–3.0 mg/kg, i.v.) elicited significant, F(4, 20) ⫽ 10.7, p ⬍ 0.001, dose-dependent increases in MAP (Fig. 1A). Am ...
Arrhythmias in the developing heart
... La/SSB antibodies are typically found in mothers affected by the above-mentioned autoimmune diseases. The risk of developing foetal complete heart block in pregnant women with positive anti-Ro/SSA antibodies is about 2% (Brucato et al. 2001). These antibodies cause myocardial inflammation specifical ...
... La/SSB antibodies are typically found in mothers affected by the above-mentioned autoimmune diseases. The risk of developing foetal complete heart block in pregnant women with positive anti-Ro/SSA antibodies is about 2% (Brucato et al. 2001). These antibodies cause myocardial inflammation specifical ...
European Journal of Preventive Cardiology
... cardiovascular and skeletal muscle function, quality of life, general healthy lifestyle, and reduction of depressive symptoms and psychosocial stress is nowadays well recognized. However, it remains largely obscure, which characteristics of physical activity (PA) and exercise training frequency, int ...
... cardiovascular and skeletal muscle function, quality of life, general healthy lifestyle, and reduction of depressive symptoms and psychosocial stress is nowadays well recognized. However, it remains largely obscure, which characteristics of physical activity (PA) and exercise training frequency, int ...
Stable Angina and If Inhibition: New Insights and
... in patients having experienced acute coronary events, and lower incidence of the disease, especially among younger people, resulting from more effective primary and secondary prevention of atherosclerosis. The absolute number of coronary events remains relatively constant. This means that in practic ...
... in patients having experienced acute coronary events, and lower incidence of the disease, especially among younger people, resulting from more effective primary and secondary prevention of atherosclerosis. The absolute number of coronary events remains relatively constant. This means that in practic ...
Drug Treatment of Ischaemic Heart Disease
... (Zestril,Prinvil), Ramipril (Tritace), Perindopril (Coversyl) - Class effect Treat & prevent left ventricular failure 3-30 lives saved/ 1000 patients Some patients short term (6/52) only Start early and aim for highest doses Captopril - 50mg TDS, Lisinopril 20mg D, Ramipril 10mg D Judith Coombes ...
... (Zestril,Prinvil), Ramipril (Tritace), Perindopril (Coversyl) - Class effect Treat & prevent left ventricular failure 3-30 lives saved/ 1000 patients Some patients short term (6/52) only Start early and aim for highest doses Captopril - 50mg TDS, Lisinopril 20mg D, Ramipril 10mg D Judith Coombes ...
The Importance of Potassium
... The findings of the Scottish researchers, to a large extent, fly against conventional medical wisdom. The medical profession has always considered potassium levels above 5.1 mmol/L a far greater risk of ventricular arrhythmia than levels below 3.5 mmol/L. Yet, the Scottish report points out that the ...
... The findings of the Scottish researchers, to a large extent, fly against conventional medical wisdom. The medical profession has always considered potassium levels above 5.1 mmol/L a far greater risk of ventricular arrhythmia than levels below 3.5 mmol/L. Yet, the Scottish report points out that the ...
2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS Guideline for the
... The writing committee gratefully acknowledges the memory of James T. Dove, MD, who died during the development of this document but contributed immensely to our understanding of stable ischemic heart disease. This document was approved by the American College of Cardiology Foundation Board of Truste ...
... The writing committee gratefully acknowledges the memory of James T. Dove, MD, who died during the development of this document but contributed immensely to our understanding of stable ischemic heart disease. This document was approved by the American College of Cardiology Foundation Board of Truste ...
Boundless Study Slides
... Boundless is an innovative technology company making education more affordable and accessible for students everywhere. The company creates the world’s best open educational content in 20+ subjects that align to more than 1,000 popular college textbooks. Boundless integrates learning technology into ...
... Boundless is an innovative technology company making education more affordable and accessible for students everywhere. The company creates the world’s best open educational content in 20+ subjects that align to more than 1,000 popular college textbooks. Boundless integrates learning technology into ...
Libby: Braunwald`s Heart Disease
... or IV) or those who have less severe symptoms or are asymptomatic but demonstrate “high-risk” criteria for an adverse outcome on noninvasive testing should undergo coronary arteriography. High-risk features include resting or exercise-induced left ventricular dysfunction (left ventricular ejection f ...
... or IV) or those who have less severe symptoms or are asymptomatic but demonstrate “high-risk” criteria for an adverse outcome on noninvasive testing should undergo coronary arteriography. High-risk features include resting or exercise-induced left ventricular dysfunction (left ventricular ejection f ...
Clinical Significance of the Acoustic Detection of Coronary Artery
... The sounds of mild stenotic lesions are difficult to detect in an outpatient environment. Clinical use of our detection system will allow detection of stenotic lesions at an early stage, which will help to overcome the continuing difficulties of preventing the development of coronary artery disease ...
... The sounds of mild stenotic lesions are difficult to detect in an outpatient environment. Clinical use of our detection system will allow detection of stenotic lesions at an early stage, which will help to overcome the continuing difficulties of preventing the development of coronary artery disease ...
Translating Novel Imaging Technologies Into Clinical Applications
... of patients with moderate or severe disease and can be because of either low flow states (as a consequence of a depressed left ventricular ejection fraction or a small ventricle) or inaccuracies in echocardiographic measurements coupled with inconsistent thresholds in current guidelines.27,28 Indeed ...
... of patients with moderate or severe disease and can be because of either low flow states (as a consequence of a depressed left ventricular ejection fraction or a small ventricle) or inaccuracies in echocardiographic measurements coupled with inconsistent thresholds in current guidelines.27,28 Indeed ...
Cardiovascular disease
Cardiovascular disease (CVD) is a class of diseases that involve the heart or blood vessels. Cardiovascular disease includes coronary artery diseases (CAD) such as angina and myocardial infarction (commonly known as a heart attack). Other CVDs are stroke, hypertensive heart disease, rheumatic heart disease, cardiomyopathy, atrial fibrillation, congenital heart disease, endocarditis, aortic aneurysms, peripheral artery disease and venous thrombosis.The underlying mechanisms vary depending on the disease in question. Coronary artery disease, stroke, and peripheral artery disease involve atherosclerosis. This may be caused by high blood pressure, smoking, diabetes, lack of exercise, obesity, high blood cholesterol, poor diet, and excessive alcohol consumption, among others. High blood pressure results in 13% of CVD deaths, while tobacco results in 9%, diabetes 6%, lack of exercise 6% and obesity 5%. Rheumatic heart disease may follow untreated strep throat.It is estimated that 90% of CVD is preventable. Prevention of atherosclerosis is by decreasing risk factors through: healthy eating, exercise, avoidance of tobacco smoke and limiting alcohol intake. Treating high blood pressure and diabetes is also beneficial. Treating people who have strep throat with antibiotics can decrease the risk of rheumatic heart disease. The effect of the use of aspirin in people who are otherwise healthy is of unclear benefit. The United States Preventive Services Task Force recommends against its use for prevention in women less than 55 and men less than 45 years old; however, in those who are older it is recommends in some individuals. Treatment of those who have CVD improves outcomes.Cardiovascular diseases are the leading cause of death globally. This is true in all areas of the world except Africa. Together they resulted in 17.3 million deaths (31.5%) in 2013 up from 12.3 million (25.8%) in 1990. Deaths, at a given age, from CVD are more common and have been increasing in much of the developing world, while rates have declined in most of the developed world since the 1970s. Coronary artery disease and stroke account for 80% of CVD deaths in males and 75% of CVD deaths in females. Most cardiovascular disease affects older adults. In the United States 11% of people between 20 and 40 have CVD, while 37% between 40 and 60, 71% of people between 60 and 80, and 85% of people over 80 have CVD. The average age of death from coronary artery disease in the developed world is around 80 while it is around 68 in the developing world. Disease onset is typically seven to ten years earlier in men as compared to women.