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65 Commentary - The Ideal DBS System The proliferation of DBS
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... in the cortex. High sodium channel density and/or sodium channels with a shifted voltage dependence at relatively proximal parts of the axon (5, 19) and the highdensity synaptic input in an area with a very high surface-to-volume ratio favor the output-generating effectiveness of depolarizing inputs ...
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The Elementary Nervous System Revisited1
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Multiple sites of spike initiation in a single dendritic
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... extracellular recording from the ventrolateral surface of the desheathed interganglionic connectives that contain the axons of the MTIs. The sixth abdominal ganglion was desheathed and probed from the ventral surface with 3 M KCl-filled micropipettes having resistances in the range of 40-60 M R when ...
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Node of Ranvier



The nodes of Ranvier also known as myelin sheath gaps, are the gaps (approximately 1 micrometer in length) formed between the myelin sheaths generated by different cells. A myelin sheath is a many-layered coating, largely composed of a fatty substance called myelin, that wraps around the axon of a neuron and very efficiently insulates it. At nodes of Ranvier, the axonal membrane is uninsulated and, therefore, capable of generating electrical activity.
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