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co-occurring sad symptomatology and schizophrenia at high latitude
co-occurring sad symptomatology and schizophrenia at high latitude

... with convergent validity with other depression measures and discriminant validity with measures of positive, negative and extra-pyramidal, and medication side-effect symptoms (41). Other research has found the CDSS but not the HRSD distinguishes between depression and negative symptoms in schizophre ...
Mental disorders and their relation to brain lesion location
Mental disorders and their relation to brain lesion location

... made in Korea (2000). The aims of this study were to determine the frequency of emotional lability following first ever stroke, and to find out the relation of the location of stroke with post stroke depression and emotional lability. Emotional lability was present in 18 percent of patients (15). Th ...
Schizophrenia as one extreme of a sexually selected fitness indicator
Schizophrenia as one extreme of a sexually selected fitness indicator

... tails persist. They are heritable, and males with the most beautiful tails do virtually all of the mating and reproducing (Petrie et al., 1991). The puzzle is why the ugly tails persist as they do. That paradox has been studied enough to have been named (‘‘the paradox of the lek’’) (Kirkpatrick and ...
Shaner-Miller
Shaner-Miller

... tails persist. They are heritable, and males with the most beautiful tails do virtually all of the mating and reproducing (Petrie et al., 1991). The puzzle is why the ugly tails persist as they do. That paradox has been studied enough to have been named (‘‘the paradox of the lek’’) (Kirkpatrick and ...
2.15 MBscz_course_natural_history_prognosis
2.15 MBscz_course_natural_history_prognosis

... † Combined social and work functioning used to define good functional outcome. ‡ Requires no hospitalizations, good or adequate social and work functioning, and symptom ratings of mild or less for a period of 1 year. Ventura J et al. Schizophr Res. 2011;132(1):18-23. ...
Psychiatric emergency
Psychiatric emergency

... Sings of arousal and aggitation Family history of aggression ...
Seeing more clearly - Rutgers University Behavioral Health Care
Seeing more clearly - Rutgers University Behavioral Health Care

... which concave objects appear as convex. It remains unclear, however, the extent to which this perceptual advantage uniquely characterizes the schizophrenia phenotype. To address the foregoing, we compared 30 bipolar disorder patients to a previously published sample of healthy controls (N = 25) and ...
Schizophrenia Treatment and Self-Help: Getting All the Help You
Schizophrenia Treatment and Self-Help: Getting All the Help You

... Try to get plenty of sleep. When you’re on medication, you most likely need even more sleep (/articles/sleep/getting-better-sleep.htm) than the standard 8 hours. Many people with schizophrenia have trouble with sleep, but getting regular exercise, reducing sugar in your diet, and avoiding caffeine c ...
Running Head: SCHIZOPHRENIC SPEECH 1
Running Head: SCHIZOPHRENIC SPEECH 1

... deterioration,  genetics,  and  neurotransmitter  dysfunction.  In  patients  with   schizophrenia,  there  is  reduced  activity  and  blood  flow  in  the  frontal  lobe.  The   frontal  lobe  is  responsible  for  short-­‐term  memory,  exec ...
Can supplementation with vitamin E or C and omega-3 or
Can supplementation with vitamin E or C and omega-3 or

... Two terms are commonly used to categorize the symptoms of schizophrenia. Positive symptoms refer to new mental phenomena, which unaffected people normally do not experience, such as hallucinations and delusions. Negative symptoms refer to a loss of normal mental functions leading for example to amot ...
Schizophrenia: Causes, Crime, and Implications for
Schizophrenia: Causes, Crime, and Implications for

... Fisher, Silver and Wolff (2006, p.11) call for a “criminological–informed” framework for mental health services because mental health workers of often not aware of the risks for criminal behavior that do not involve aspects of the individuals’ mental health. Likewise, we call for a “mental health” i ...
Neuroleptics and Anxiolytics
Neuroleptics and Anxiolytics

... and abnormal experiences, such as the perception of loss of control of one’s thoughts. Patients lose empathy with others, become withdrawn, and demonstrate inappropriate or blunted mood. Schizophrenic symptoms: Positive: can be regarded as an abnormality (incoherent speech, agitation). Negative: ind ...
Neuroleptics and Anxiolytics
Neuroleptics and Anxiolytics

... and abnormal experiences, such as the perception of loss of control of one’s thoughts. Patients lose empathy with others, become withdrawn, and demonstrate inappropriate or blunted mood. Schizophrenic symptoms: Positive: can be regarded as an abnormality (incoherent speech, agitation). Negative: ind ...
Static posed and evoked facial expressions of emotions in
Static posed and evoked facial expressions of emotions in

... Antipsychotics, particularly first-generation, are associated with extrapyramidal symptoms, but their influence on emotion expression remains unclear. Some studies indicated an adverse effect of medications on facial expression (Gaebel and Wolwer, 2004; Schneider et al., 1992). Others (Earnst et al. ...
A Candidate Molecule Approach to Defining
A Candidate Molecule Approach to Defining

... large number of genetic studies have indicated that inheriting certain genes imparts risk for developing schizophrenia (Asherson et al. 1995). If a faulty gene has been inherited by an individual not yet exhibiting symptoms of schizophrenia, it may affect brain development and susceptibility to schi ...
Schizophrenia and Violence: Myths, Realities, and Treatments
Schizophrenia and Violence: Myths, Realities, and Treatments

... • Violent acts committed by people with schizophrenia account for only a small portion of overall violence, and far less than that attributed to substance abuse • BUT, for people who have schizophrenia, there is a significant risk for violence • AND, the consequences of violence can be serious • So, ...
At Issue: Assessment of Schizophrenia: Getting Closer to the Cause
At Issue: Assessment of Schizophrenia: Getting Closer to the Cause

... that current diagnostic categories are in one-to-one correspondence with nature. The discovery of biological mechanisms underlying psychopathology is more likely to revolutionize psychiatric diagnosis than reveal hundreds of types of unique neuropathological variants, each mapping onto a specific DS ...
Clinical Variables and Genetic Loading for
Clinical Variables and Genetic Loading for

... "loose associations" was the only symptom characteristic of this dimension that was described in probands. No significant association was found for age at onset in the current study. Early age at onset has been associated with higher familial liability in some studies of schizophrenia (Kendler et al ...
Dilip Jeste Thomas A. Ban
Dilip Jeste Thomas A. Ban

... TB: So, you were ready to do a residency in psychiatry? DJ: Yes, I went to Bombay, and met Dr. Vahia at GS Medical College and King Edward Memorial (KEM) Hospital. It was the best hospital and medical school in Bombay. Of course I am biased. My wife went to another medical school in Bombay, Grant Me ...
Chapter 16 Psychological Disorders
Chapter 16 Psychological Disorders

... When physicians discovered that syphilis led to mental disorders, they started using _______________________________ to review the physical causes of these disorders. 1. _________________: Cause and development of the disorder. 2. __________________: Identifying (symptoms) and distinguishing one dis ...
Comer, Abnormal Psychology, 8th edition
Comer, Abnormal Psychology, 8th edition

... that possible gene defects on numerous chromosomes may predispose individuals to develop schizophrenia • These varied findings may indicate: • A case of “mistaken identity” – that is, some of these gene sites do not contribute to the disorder; • Different types of schizophrenia are linked to differe ...
Effectiveness of Exercise as an Adjunct Therapy
Effectiveness of Exercise as an Adjunct Therapy

... Schizophrenia is a severe mental illness characterized by hallucinations, disorganized or catatonic behavior and patients may also have an inappropriate or depressed affect and associative looseness (Varcarolis & Halter, 2010, p. 307). Schizophrenia has two main classes of symptoms: positive and neg ...
PowerPoint * Lecture Notes Presentation Chapter 2
PowerPoint * Lecture Notes Presentation Chapter 2

...  Medication that targets glutamate shows promise © 2015 John Wiley & Sons, Inc. All rights reserved. ...
A New Look at the Neural Diathesis–Stress Model of Schizophrenia
A New Look at the Neural Diathesis–Stress Model of Schizophrenia

... with schizotypal personality disorder14 and schizophrenia,15 as well as being positively related to the positive, but not negative, symptoms of schizophrenia.16 Other studies have found no elevation of basal cortisol levels in schizophrenia17 or in those at ultrahigh risk of psychosis.18 One way to ...
The Tragedy of Schizophrenia without Psychotherapy
The Tragedy of Schizophrenia without Psychotherapy

... stopped getting better, and psychotherapies have been succeeded by physical treatments that claim to be more scientific, which do not require understanding the patients and which have economic advantages for everyone except the patients. And the myth of incurability has been re-created. In the 1930s ...
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Mechanisms of schizophrenia



The underlying mechanisms of schizophrenia, a mental disorder characterized by a disintegration of the processes of thinking and of emotional responsiveness, are complex. A number of theories attempt to explain the link between altered brain function and schizophrenia, the most important of which are the dopamine hypothesis and the glutamate hypothesis. Note that these theories are separate from the causes of schizophrenia, which deal with actual starting points of the illness instead, e.g. genetic and environmental factors. The current theories attempt to explain how changes in brain functioning can contribute to symptoms of the disease.
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