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Dose-Response Relationships and Plasma Concentrations of
Dose-Response Relationships and Plasma Concentrations of

... Determination of digitalis plasma level is a commonly used method of monitoring glycoside therapy. For the diagnosis of glycoside intoxication, the value of this method appears well established [17]. However, there are few data about the relationship between therapeutic plasma levels of digitalis an ...
3D printing, heart
3D printing, heart

... succeeded in generating a cartilage tissue of the ear for a mouse in their lab. This is indeed a big stride in the 3D printing journey and marks the beginning of a tremendous innovation. This development follows that of a Missouri professor who succeeded in printing out 3D chicken hearts back in 200 ...
TEXAS TECH UNIVERSITY HEALTH SCIENCE CENTER HEALTH
TEXAS TECH UNIVERSITY HEALTH SCIENCE CENTER HEALTH

... or beat in question meets any of these criteria, again, we are going to call it atrial. Matching upright Ps and an atrial rate grater than 160 by textbook definition is an atrial rhythm. So even if you have your upright P-waves, which we usually think of coming from the SA node, if that heart rate ...
Nonlinear oscillator model reproducing various phenomena in the
Nonlinear oscillator model reproducing various phenomena in the

... the action potentials of the nodes, and y i are the currents acting on these nodes. Our modification does not change the structure of the phase space of the system: in the phase space of the system, there will always be an unstable focus, a stable node, and a saddle.12 Note that if e and d have oppo ...
PAUL M. ZOLL, M.D. Invasive Temporary Pacing
PAUL M. ZOLL, M.D. Invasive Temporary Pacing

... effectshave been documented since its introduction in 1952,even in the presence of competition between the artificial pacemakerand intrinsic rhythm, or during acute myocardial infarction. The NTP has now been used in thousands of patients: clinical experience has beenaccumulating,and many clinical t ...
PAPILLIFEROUS TUMOURS OF THE HEART VALVES
PAPILLIFEROUS TUMOURS OF THE HEART VALVES

... Exceptionally, much larger polyps occur on the cardiac valves in the form of papilliferous tumours. Even these usually occur in otherwise normal hearts and rarely give rise to symptoms. Bohrod (1929) for instance described them as "small, harmless bodies". However, the present report of two further ...
Right Ventricular Pacing for Right Ventricular Outflow Tract Obstruction
Right Ventricular Pacing for Right Ventricular Outflow Tract Obstruction

... Angiography was performed to measure and characterize the gradient across the RVOT. There was a hemodynamically significant gradient of 54 mmHg (mean, 33 mmHg). When the patient coughed and then performed the Valsalva maneuver, the peak gradients increased to 94 mmHg and 106 mmHg, respectively. Po ...
Process Paper
Process Paper

... 2010). Pacemakers are put right under the skin during a minor surgical procedure and the pacemaker can be felt under the skin (WebMD, 2010). In a healthy heart, the heart’s right and left ventricles pump at the same time and in rhythm with the atrium, but in a CHF heart, the ventricles don’t pump at ...
What Happens to the Human Heart in Space?
What Happens to the Human Heart in Space?

... control the cardiovascular system within a few heart beats. However, since different phases of the parabolic flight profile last for no longer than 20-25 seconds, it is to be expected that ANS activity will also be influenced by conditions during previous phases, i.e. hypergravity. This activity wil ...
Hypoplastic left heart syndrome
Hypoplastic left heart syndrome

... There is no communication between the left atrium and left ventricle. This may be due to a complete absence of the left atrioventricular connection or an imperforate mitral valve. Typically, the left ventricle is slit-like and there may be no demonstrable left ventricular cavity at all (Figure 1). A ...
Syndrome of Left Ventricular-Right Atrial
Syndrome of Left Ventricular-Right Atrial

096 Heart rate reserve in ACHD - Diller - Circ 2006
096 Heart rate reserve in ACHD - Diller - Circ 2006

... with similar demographic characteristics (3–7). Development of simple risk stratification methods would permit resources to be directed to patients with adult congenital heart disease (ACHD) at greatest risk. Cardiopulmonary exercise testing with measurement of peak oxygen consumption is increasingl ...
16. 7_ortirilgan_yurak_porok
16. 7_ortirilgan_yurak_porok

Thirty-Five Years of Mechanical Circulatory Support at the Texas
Thirty-Five Years of Mechanical Circulatory Support at the Texas

... eplacing the failing human heart has had a turbulent history. The 1st human-to-human heart transplantation, performed by Christiaan Barnard in 1967,1 marked an exciting advance in cardiac surgery. It revealed to the medical community at large and to the public that failing hearts could be replaced, ...
Myocardial Contractility and Assessment of Cardiac Function
Myocardial Contractility and Assessment of Cardiac Function

... by the lumen size of pulmonary vessels [13]. Further, the pulmonary vascular resistance is defined as the difference of mean alveolar pressure and left atrial (LA) pressure divided by pulmonary blood flow. A change in any of these factors may therefore give rise to pulmonary hypertension. Pulmonary ...
Heart failure traffic lights
Heart failure traffic lights

... Indicated in those patients with ongoing symptoms (NYHA II -IV) despite other medical therapy. Before initiating spironolactone any potassium supplements should be discontinued. Eplerenone — second line aldosterone antagonist if spironolactone is not tolerated Eplerenone has evidence of benefit in p ...
Novel Bio-markers in heart failure: differences in regional circulatory
Novel Bio-markers in heart failure: differences in regional circulatory

... our findings and plasma concentrations in samples that would be obtained in routine practice. We did not specifically cannulate and obtain samples from the renal or splanchnic veins that might have demonstrated more pronounced changes. This population was heterogeneous with only five patients having ...
ipej.org - Cogprints
ipej.org - Cogprints

... a left bundle branch block pattern (Figure 1F) with a frontal plane axis ranging from -30 to -60 degrees or +60 to +165 degrees. 14 The inducibility of sustained monomorphic ventricular tachycardia in the electrophysiology laboratory was high among those presenting with a clinical episode. Heart dis ...
Influence of aortic valve disease on systolic stiffness of
Influence of aortic valve disease on systolic stiffness of

... During the early period of study, the baseline cineangiogram was obtained before infusion of nitroprusside and the second angiogram. However, we soon learned that it was easier to reduce load with nitroprusside before rather than after the first injection of contrast. Subsequently, the nitroprusside ...
Moderate Exercise Training Improves Survival and Ventricular
Moderate Exercise Training Improves Survival and Ventricular

... Kaplan-Meier analysis with log-rank test. Statistical significance was set at a P⬍0.05. Data and statistical analysis were performed using Graph Pad Prism version 5.01 for Windows (Graph Pad Software, San Diego, Calif). Sample sizes were calculated based on a previous survival study15 to ensure a 0. ...
Echo-Doppler–derived indexes of ventricular stiffness and ventriculo
Echo-Doppler–derived indexes of ventricular stiffness and ventriculo

... echocardiography [10]. Exclusion criteria were (1) muscular dystrophy, (2) more than moderate valvular disease, (3) previously documented AF or atrial flutter on the electrocardiogram (ECG) or Holter monitoring, (4) significant lung disease and (5) a New York Heart Association functional classificat ...
Cardiac Rehabilitation Jan-09-07
Cardiac Rehabilitation Jan-09-07

... includes three phases: Warm-up for 5 to 10 minutes. Warm-up exercises consist of stretching, flexibility movements  Conditioning or training phase, which consists of at least 20 minutes and preferably 30 to 45 minutes of continuous aerobic activity.  Cool-down for 5 to 10 minutes. permits a gradua ...
Table 1
Table 1

... eliminates AF in many cases and emphasizes the importance of these triggers located in the muscular sleeves (3,4). Such sleeves are also present in the normal heart, and the reasons for the maintenance of triggering activity are largely unknown. Experimental studies have shown that parasympathetic s ...
The thick left ventricular wall of the giraffe heart normalises wall
The thick left ventricular wall of the giraffe heart normalises wall

... such massive arterial pressures. We hypothesized that giraffe hearts have a small intraventricular cavity and a relatively thick ventricular wall, allowing for generation of high arterial pressures at normal left ventricular wall tension. In nine anaesthetized giraffes (495±38 kg), we determined in ...
21_ClickerQuestionsPRS
21_ClickerQuestionsPRS

... c. The internal organization of the left ventricle resembles that of the right ventricle, which contains more prominent trabeculae carneae. d. There are two large papillary muscles, rather than three, which are associated with a moderator band. ...
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Electrocardiography



Electrocardiography (ECG or EKG*) is the process of recording the electrical activity of the heart over a period of time using electrodes placed on a patient's body. These electrodes detect the tiny electrical changes on the skin that arise from the heart muscle depolarizing during each heartbeat.In a conventional 12 lead ECG, ten electrodes are placed on the patient's limbs and on the surface of the chest. The overall magnitude of the heart's electrical potential is then measured from twelve different angles (""leads"") and is recorded over a period of time (usually 10 seconds). In this way, the overall magnitude and direction of the heart's electrical depolarization is captured at each moment throughout the cardiac cycle. The graph of voltage versus time produced by this noninvasive medical procedure is referred to as an electrocardiogram (abbreviated ECG or EKG).During each heartbeat, a healthy heart will have an orderly progression of depolarization that starts with pacemaker cells in the sinoatrial node, spreads out through the atrium, passes through the atrioventricular node down into the bundle of His and into the Purkinje fibers spreading down and to the left throughout the ventricles. This orderly pattern of depolarization gives rise to the characteristic ECG tracing. To the trained clinician, an ECG conveys a large amount of information about the structure of the heart and the function of its electrical conduction system. Among other things, an ECG can be used to measure the rate and rhythm of heartbeats, the size and position of the heart chambers, the presence of any damage to the heart's muscle cells or conduction system, the effects of cardiac drugs, and the function of implanted pacemakers.
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