CD4+ T-Cell-Independent Secondary Immune Responses to
... Pneumocystis infection upon adoptive transfer into Rag1(−/−) mice (3). As such, CD4+ T-cells have been a primary focus in the study of host defense against this pathogen. However, it has also been shown that adoptive transfer of hyperimmune serum mediates effective passive immunity to Pneumocystis i ...
... Pneumocystis infection upon adoptive transfer into Rag1(−/−) mice (3). As such, CD4+ T-cells have been a primary focus in the study of host defense against this pathogen. However, it has also been shown that adoptive transfer of hyperimmune serum mediates effective passive immunity to Pneumocystis i ...
Clinical Significance of the Acoustic Detection of Coronary Artery
... intercostal spaces. Approximately 400 msec of waveforms immediately following the second heart sound were passed through a band pass filter (400−1,500 Hz)and subjected to frequency analysis using the maximum entropy method. The ratio of heart sound amplitudes within the 400−700 Hz band to those with ...
... intercostal spaces. Approximately 400 msec of waveforms immediately following the second heart sound were passed through a band pass filter (400−1,500 Hz)and subjected to frequency analysis using the maximum entropy method. The ratio of heart sound amplitudes within the 400−700 Hz band to those with ...
Prosthetic Heart Valves in the Aortic Position: A Review Hadi
... continuously contract rhythmically. It should be noted that the regular contraction in cardiomyofibrils is either maximum (100% contraction) or nothing (0% contraction), unlike skeletal muscle cells. This strongly indicates the lack of neural network contribution to the regular heart construction. I ...
... continuously contract rhythmically. It should be noted that the regular contraction in cardiomyofibrils is either maximum (100% contraction) or nothing (0% contraction), unlike skeletal muscle cells. This strongly indicates the lack of neural network contribution to the regular heart construction. I ...
Antibodies to Chlamydia trachomatis heat shock proteins in women
... The risk of infertility increases after repeated episodes of salpingitis (Weström, 1980). Infertility after salpingitis is due to occlusion of the Fallopian tubes by fibrous scarring. Such scarring may occur as the result of an immunopathological response after chronic or recurrent infection by C. ...
... The risk of infertility increases after repeated episodes of salpingitis (Weström, 1980). Infertility after salpingitis is due to occlusion of the Fallopian tubes by fibrous scarring. Such scarring may occur as the result of an immunopathological response after chronic or recurrent infection by C. ...
Impact of Anti-Oxidized Low- Density Lipoprotein
... The changes and correlations of Ox LDL Abs, anti-beta-2glycoprotein I IgG and antiphospholipid antibodies explain the immunological mechanism between thrombotic and atherosclerotic processes in the human body [3,13,14], therefore indicating that the increased concentration of Ox LDL Abs correlates w ...
... The changes and correlations of Ox LDL Abs, anti-beta-2glycoprotein I IgG and antiphospholipid antibodies explain the immunological mechanism between thrombotic and atherosclerotic processes in the human body [3,13,14], therefore indicating that the increased concentration of Ox LDL Abs correlates w ...
Cellulitis, preseptal and orbital
... Cellulitis means inflammation of the soft tissues, often due to infection. Preseptal and orbital cellulitis are infections, of the soft tissues in the socket that surrounds the eye, usually caused by common bacteria. They may follow a cold, sinusitis, an infection of the eyelid such as a stye, an in ...
... Cellulitis means inflammation of the soft tissues, often due to infection. Preseptal and orbital cellulitis are infections, of the soft tissues in the socket that surrounds the eye, usually caused by common bacteria. They may follow a cold, sinusitis, an infection of the eyelid such as a stye, an in ...
FUNGAL PHASE REMEDIES - Dr. Karin Wagstaff : Doctor of
... antigenic when coupled with a large molecular carrier such as a protein. ...
... antigenic when coupled with a large molecular carrier such as a protein. ...
Rheology of discrete subaortic stenosis - Heart
... heology, as the science of flow and deformation of matter, would seem to apply to the discrete form of fixed subaortic stenosis, the development of which is poorly understood. It has become apparent in recent years that this is an acquired lesion that is rarely seen in the newborn or neonatal period ...
... heology, as the science of flow and deformation of matter, would seem to apply to the discrete form of fixed subaortic stenosis, the development of which is poorly understood. It has become apparent in recent years that this is an acquired lesion that is rarely seen in the newborn or neonatal period ...
A Comprehensive look At heart structure, function, and health
... C–reactive protein ― used as an indicator for heart disease, C-reactive protein is a test that measures the concentration of a protein in serum that indicates acute inflammation. defibrillator ― medical device used in the defibrillation of the heart. It consists of a central unit and a set of ...
... C–reactive protein ― used as an indicator for heart disease, C-reactive protein is a test that measures the concentration of a protein in serum that indicates acute inflammation. defibrillator ― medical device used in the defibrillation of the heart. It consists of a central unit and a set of ...
Atrial Electrophysiological Remodeling and Fibrillation in Heart Failure
... dogs.27 These data point toward a complex electrical phenotype and underlying ionic mechanism changes in the atrium in the presence of HF, depending upon the severity of the condition (short-term versus long-term ventricular pacing), 31 and, in part, mirror the complex and varied phenotypes seen in ...
... dogs.27 These data point toward a complex electrical phenotype and underlying ionic mechanism changes in the atrium in the presence of HF, depending upon the severity of the condition (short-term versus long-term ventricular pacing), 31 and, in part, mirror the complex and varied phenotypes seen in ...
acute viral myocarditis: current concepts in diagnosis and treatment reviews
... and to rule out other causes of heart failure, such as valvular, usually good in fulminant myocarditis if patients survive the congenital, or amyloid heart disease. Classic findings include initial phase. This is in contrast to acute myocarditis in which global hypokinesis with or without pericardia ...
... and to rule out other causes of heart failure, such as valvular, usually good in fulminant myocarditis if patients survive the congenital, or amyloid heart disease. Classic findings include initial phase. This is in contrast to acute myocarditis in which global hypokinesis with or without pericardia ...
Trans-Septal Puncture Procedures and Devices
... even if the needle or catheter cannot be visualized. Newer imTS ⴝ transseptal aging modalities such as intracarTTE ⴝ transthoracic echocardiography diac echocardiography (AcuNav ICE, Siemens Medical Systems, Mountain View, California) (12,14,15) have also been used with success. The role of 3-dimens ...
... even if the needle or catheter cannot be visualized. Newer imTS ⴝ transseptal aging modalities such as intracarTTE ⴝ transthoracic echocardiography diac echocardiography (AcuNav ICE, Siemens Medical Systems, Mountain View, California) (12,14,15) have also been used with success. The role of 3-dimens ...
Task Force Report Guidelines for the diagnosis and treatment of chronic
... typically breathlessness or fatigue, either at rest or during exertion, or ankle swelling and objective evidence of cardiac dysfunction at rest (Table 1). A clinical response to treatment directed at heart failure alone is not sufficient for diagnosis, although the patient should generally demonstrate ...
... typically breathlessness or fatigue, either at rest or during exertion, or ankle swelling and objective evidence of cardiac dysfunction at rest (Table 1). A clinical response to treatment directed at heart failure alone is not sufficient for diagnosis, although the patient should generally demonstrate ...
Neutrophils in tuberculosis
... Factor (TNF) [30]. Sometimes the reverse may happen; ingestion of apoptotic cell with pathogen may result in pro inflammatory effect [30]. This may be due to expression of heat shock proteins [31] or activation of macrophages by neutrophil proteases. Phagocytosis of apoptotic cell may produce anti/p ...
... Factor (TNF) [30]. Sometimes the reverse may happen; ingestion of apoptotic cell with pathogen may result in pro inflammatory effect [30]. This may be due to expression of heat shock proteins [31] or activation of macrophages by neutrophil proteases. Phagocytosis of apoptotic cell may produce anti/p ...
FB sub-tarsal - Vision 2020 UK
... - dilate puncta with progressive diameter punctal dilator - take care not to traumatise tissues - periodic repetition may be required Lacrimal lavage (saline syringing) may be effective in cases of - local (discrete) obstruction - subacute inflammation or infection - less likely to be effective: - i ...
... - dilate puncta with progressive diameter punctal dilator - take care not to traumatise tissues - periodic repetition may be required Lacrimal lavage (saline syringing) may be effective in cases of - local (discrete) obstruction - subacute inflammation or infection - less likely to be effective: - i ...
FB sub-tarsal - Vision 2020 UK
... - dilate puncta with progressive diameter punctal dilator - take care not to traumatise tissues - periodic repetition may be required Lacrimal lavage (saline syringing) may be effective in cases of - local (discrete) obstruction - subacute inflammation or infection - less likely to be effective: - i ...
... - dilate puncta with progressive diameter punctal dilator - take care not to traumatise tissues - periodic repetition may be required Lacrimal lavage (saline syringing) may be effective in cases of - local (discrete) obstruction - subacute inflammation or infection - less likely to be effective: - i ...
Emerging mechanisms of T-tubule remodelling in heart failure
... T-tubule system of a myocyte. The appreciation of T-tubule remodelling in heart disease was boosted during the last decade by the application of laser scanning confocal microscopy and the use of fluorescent lipophilic membrane markers. Among these, He et al. 53 were the first to identify and quantif ...
... T-tubule system of a myocyte. The appreciation of T-tubule remodelling in heart disease was boosted during the last decade by the application of laser scanning confocal microscopy and the use of fluorescent lipophilic membrane markers. Among these, He et al. 53 were the first to identify and quantif ...
HuCAL® Antibodies Technical Manual Introduction to Recombinant
... response to invading foreign particles (antigens) such as microorganisms and viruses. They play a critical role in the immune system’s defense against infection and disease. Ideally, every antibody recognizes and binds to just one antigen. In reality, most antibodies are not fully monospecific and w ...
... response to invading foreign particles (antigens) such as microorganisms and viruses. They play a critical role in the immune system’s defense against infection and disease. Ideally, every antibody recognizes and binds to just one antigen. In reality, most antibodies are not fully monospecific and w ...
Yoga and Immunity - Living Room Yoga
... • “A substance in the body that is normally confined to a specific area (and thus is hidden from the immune system) is released into the bloodstream. For example, a blow to the eye can cause the fluid in the eyeball to be released into the bloodstream. The fluid stimulates the immune system to recog ...
... • “A substance in the body that is normally confined to a specific area (and thus is hidden from the immune system) is released into the bloodstream. For example, a blow to the eye can cause the fluid in the eyeball to be released into the bloodstream. The fluid stimulates the immune system to recog ...
Genetic analysis of innate immunity in resistance to
... host defenses,3 to date, no specific genes have been shown to cause a predisposition to infection. However, there is some anecdotal evidence that patients with congenital defects affecting phagocyte function, such as myeloperoxidase (MPO) deficiency, have a higher occurrence of systemic candidiasis ...
... host defenses,3 to date, no specific genes have been shown to cause a predisposition to infection. However, there is some anecdotal evidence that patients with congenital defects affecting phagocyte function, such as myeloperoxidase (MPO) deficiency, have a higher occurrence of systemic candidiasis ...
Immunology and Serology
... publication for educational, not-for-profit use by health care workers, students or faculty. All copies must retain all author credits and copyright notices included in the original document. Under no circumstances is it permissible to sell or distribute on a commercial basis, or to claim authorship ...
... publication for educational, not-for-profit use by health care workers, students or faculty. All copies must retain all author credits and copyright notices included in the original document. Under no circumstances is it permissible to sell or distribute on a commercial basis, or to claim authorship ...
immunochemical mechanisms involved in penicillin hypersensitivity
... (1) Benzylpenicilloyl-specific antibodies were detected by direct skin tests (Levine and Ovary, 1961; Levine and Price, 1964; Parker, Shapiro, Kern and Eisen, 1962) and by passive transfer techniques (Siegal and Levine, 1964). Skin test reagents which can be used for detection of benzylpenicilloyl ( ...
... (1) Benzylpenicilloyl-specific antibodies were detected by direct skin tests (Levine and Ovary, 1961; Levine and Price, 1964; Parker, Shapiro, Kern and Eisen, 1962) and by passive transfer techniques (Siegal and Levine, 1964). Skin test reagents which can be used for detection of benzylpenicilloyl ( ...
Chapter 6
... mitral valve. The atrial margin of the AVN is apposed to the myocardialized vestibular spine, containing the tendon of Todaro, while the ventricular margin of the AVN is continuous with the bundle of His. The slow pathway of the AVN (green) is a myocardial inferior extension of the compact part of t ...
... mitral valve. The atrial margin of the AVN is apposed to the myocardialized vestibular spine, containing the tendon of Todaro, while the ventricular margin of the AVN is continuous with the bundle of His. The slow pathway of the AVN (green) is a myocardial inferior extension of the compact part of t ...
Rheumatic fever
Rheumatic fever, also known as acute rheumatic fever (ARF), is an inflammatory disease that can involve the heart, joints, skin, and brain. The disease typically develops two to four weeks after a throat infection. Signs and symptoms include fever, multiple painful joints, involuntary muscle movements, and a characteristic but uncommon non itchy rash known as erythema marginatum. The heart is involved in about half of cases. Permanent damage to the heart valves, known as rheumatic heart disease (RHD), usually only occurs after multiple attacks but may occasionally occur after a single case of ARF. The damaged valves may result in heart failure. The abnormal valves also increase the risk of the person developing atrial fibrillation and infection of the valves.Acute rheumatic fever may occur following an infection of the throat by the bacteria Streptococcus pyogenes. If it is untreated ARF occurs in up to three percent of people. The underlying mechanism is believed to involve the production of antibodies against a person's own tissues. Some people due to their genetics are more likely to get the disease when exposed to the bacteria than others. Other risk factors include malnutrition and poverty. Diagnosis of ARF is often based on the presence of signs and symptoms in combination with evidence of a recent streptococcal infection.Treating people who have strep throat with antibiotics, such as penicillin, decreases their risk of getting ARF. This often involves testing people with sore throats for the infection, which may not be available in the developing world. Other preventative measures include improved sanitation. In those with ARF and RHD prolonged periods of antibiotics are sometimes recommended. Gradual return to normal activities may occur following an attack. Once RHD develops, treatment is more difficult. Occasionally valve replacement surgery or repair is required. Otherwise complications are treated as per normal.Acute rheumatic fever occurs in about 325,000 children each year and about 18 million people currently have rheumatic heart disease. Those who get ARF are most often between the ages of 5 and 14, with 20% of first-time attacks occurring in adults. The disease is most common in the developing world and among indigenous peoples in the developed world. In 2013 it resulted in 275,000 deaths down from 374,000 deaths in 1990. Most deaths occur in the developing world where as many as 12.5% of people affected may die each year. Descriptions of the condition are believed to date back to at least the 5th century BCE in the writings of Hippocrates. The disease is so named because its symptoms are similar to those of some rheumatic disorders.