New Insights into Mechanisms of Atrial Fibrillation
... Specialized cardiac cells associated with pacemaking, resembling pale (P) and Purkinje cells, have been observed in the pulmonary veins in rats, dogs and humans (Wit and Boyden 2007). These cells might be residua of the embryonic myocardium. Developmental studies have shown that the complicated loop ...
... Specialized cardiac cells associated with pacemaking, resembling pale (P) and Purkinje cells, have been observed in the pulmonary veins in rats, dogs and humans (Wit and Boyden 2007). These cells might be residua of the embryonic myocardium. Developmental studies have shown that the complicated loop ...
Heart Rate Variability
... Decreased HRV may explain the increased risk for cardiac mortality and morbidity in depressed patients Carney;Am J Cardiol 1995;76:562 Plexus ...
... Decreased HRV may explain the increased risk for cardiac mortality and morbidity in depressed patients Carney;Am J Cardiol 1995;76:562 Plexus ...
ACC/AHA 2006 Guidelines for the Management of Patients with
... Circulation is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Copyright © 2006 American Heart Association, Inc. All rights reserved. Print ISSN: 0009-7322. Online ISSN: 1524-4539 ...
... Circulation is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Copyright © 2006 American Heart Association, Inc. All rights reserved. Print ISSN: 0009-7322. Online ISSN: 1524-4539 ...
ACC/AHA 2006 Guidelines for the Management of Patients
... 6.1.3. Indications for Aortic Balloon Valvotomy in Adolescents and Young Adults..............e175 6.2. Aortic Regurgitation.....................................e176 6.3. Mitral Regurgitation .....................................e177 6.4. Mitral Stenosis..............................................e ...
... 6.1.3. Indications for Aortic Balloon Valvotomy in Adolescents and Young Adults..............e175 6.2. Aortic Regurgitation.....................................e176 6.3. Mitral Regurgitation .....................................e177 6.4. Mitral Stenosis..............................................e ...
ACC/AHA 2006 Guidelines for the Management of Patients With
... Robert O. Bonow, MD, FACC, FAHA, Chair Bruce Whitney Lytle, MD, FACC Blase A. Carabello, MD, FACC, FAHA Rick A. Nishimura, MD, FACC, FAHA Kanu Chatterjee, MB, FACC Patrick T. O’Gara, MD, FACC, FAHA Antonio C. de Leon, JR, MD, FACC, FAHA David P. Faxon, MD, FACC, FAHA Robert A. O’Rourke, MD, MACC, FA ...
... Robert O. Bonow, MD, FACC, FAHA, Chair Bruce Whitney Lytle, MD, FACC Blase A. Carabello, MD, FACC, FAHA Rick A. Nishimura, MD, FACC, FAHA Kanu Chatterjee, MB, FACC Patrick T. O’Gara, MD, FACC, FAHA Antonio C. de Leon, JR, MD, FACC, FAHA David P. Faxon, MD, FACC, FAHA Robert A. O’Rourke, MD, MACC, FA ...
Immunity to Intracellular Salmonella Depends on Surface
... proteomics [22], serum antibody response [23–26], as well as mutant virulence phenotypes. In addition to antigen expression, antigen immunogenicity could play a major role. Antigen detection by cognate CD4 T cells requires antigen processing and presentation of the resulting small peptides by major ...
... proteomics [22], serum antibody response [23–26], as well as mutant virulence phenotypes. In addition to antigen expression, antigen immunogenicity could play a major role. Antigen detection by cognate CD4 T cells requires antigen processing and presentation of the resulting small peptides by major ...
2008 Focused Update Incorporated Into the ACC/AHA 2006 Guidelines for... Management of Patients With Valvular Heart Disease: A Report of...
... Freed MD, Gaasch WH, Lytle BW, Nishimura RA, O’Gara PT, O’Rourke RA, Otto CM, Shah PM, Shanewise JS. 2008 Focused update incorporated into the ACC/AHA 2006 guidelines for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association ...
... Freed MD, Gaasch WH, Lytle BW, Nishimura RA, O’Gara PT, O’Rourke RA, Otto CM, Shah PM, Shanewise JS. 2008 Focused update incorporated into the ACC/AHA 2006 guidelines for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association ...
O`Rourke, Catherine M. Otto, Pravin M. Shah and
... 3.6.3.5. Serial Testing . . . . . . . . . . . . . . . . . . . . . . . . . . . . .e578 3.6.3.6. Guidelines for Physical Activity and Exercise . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .e579 3.6.3.7. Medical Therapy . . . . . . . . . . . . . . . . . . . . . .e579 3.6.3.8. Indic ...
... 3.6.3.5. Serial Testing . . . . . . . . . . . . . . . . . . . . . . . . . . . . .e578 3.6.3.6. Guidelines for Physical Activity and Exercise . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .e579 3.6.3.7. Medical Therapy . . . . . . . . . . . . . . . . . . . . . .e579 3.6.3.8. Indic ...
prolactin and autoimmune diseases prolakt
... Lymphocytes snythesize and release a biologically active form of prolactin (28) which is employed by the cells as an autocrine and paracrine growth factor. The mechanisms that control production of lymphocyte prolactin are not completely understood, and it is not known if lymphocyte prolactin is aff ...
... Lymphocytes snythesize and release a biologically active form of prolactin (28) which is employed by the cells as an autocrine and paracrine growth factor. The mechanisms that control production of lymphocyte prolactin are not completely understood, and it is not known if lymphocyte prolactin is aff ...
Mycophenolate mofetil increases susceptibility to opportunistic
... gene of interest at the end of the promoter. A 399 bp region of histone 3 terminator was amplified from C. neoformans KN99α genomic DNA using primers EB11 and EB12. EB11 primer introduced two restriction sites: HindIII followed by KasI in a front of the terminator region allowing a potential site fo ...
... gene of interest at the end of the promoter. A 399 bp region of histone 3 terminator was amplified from C. neoformans KN99α genomic DNA using primers EB11 and EB12. EB11 primer introduced two restriction sites: HindIII followed by KasI in a front of the terminator region allowing a potential site fo ...
mild fetal pericardial effusion
... clinical features accompanied and were probably responsible for the pericardial effusions. The most common cause of a fetal pericardial effusion was heart failure (13 fetuses). Fetal renal cystic dysplasia with oligohydramnios and other anomalies was present in six fetuses. Four of this group had mi ...
... clinical features accompanied and were probably responsible for the pericardial effusions. The most common cause of a fetal pericardial effusion was heart failure (13 fetuses). Fetal renal cystic dysplasia with oligohydramnios and other anomalies was present in six fetuses. Four of this group had mi ...
New Insights into Mechanisms of Atrial Fibrillation
... general population and up to 8 % of subjects over the age of 80 years (Fuster et al. 2006). AF is associated with decreased quality of life, increased morbidity and a 30 % higher risk of death (Benjamin et al. 1998), and thus is a major contributor to cardiovascular mortality. Up to 15 % of all stro ...
... general population and up to 8 % of subjects over the age of 80 years (Fuster et al. 2006). AF is associated with decreased quality of life, increased morbidity and a 30 % higher risk of death (Benjamin et al. 1998), and thus is a major contributor to cardiovascular mortality. Up to 15 % of all stro ...
The Story of Penicillin
... The Story of Penicillin z One thing they agree on: I became interested - immediately - in Fleming's paper, not because I hoped to discover a miraculous drug for the treatment of bacterial infection which for some reason had been overlooked, but because I thought it had great scientific interest. In ...
... The Story of Penicillin z One thing they agree on: I became interested - immediately - in Fleming's paper, not because I hoped to discover a miraculous drug for the treatment of bacterial infection which for some reason had been overlooked, but because I thought it had great scientific interest. In ...
EndoS and SpeB from Streptococcus pyogenes
... inability to kill the bacteria is due to reduced binding of IgG to Fc receptors and impaired classical pathwaymediated activation of complement. In addition, the activity of extracellular SpeB, which cleaves IgG into Fc and Fab fragments, also increases bacterial survival. This suggests that S. pyog ...
... inability to kill the bacteria is due to reduced binding of IgG to Fc receptors and impaired classical pathwaymediated activation of complement. In addition, the activity of extracellular SpeB, which cleaves IgG into Fc and Fab fragments, also increases bacterial survival. This suggests that S. pyog ...
ACC/AHA guidelines for the management of patients with
... When citing this document, the American College of Cardiology and the American Heart Association recommend that the following format be used: Bonow RO, Carabello B, de Leon AC Jr, Edmunds LH Jr, Fedderly BJ, Freed MD, Gaasch WH, McKay CR, Nishimura RA, O’Gara PT, O’Rourke RA, Rahimtoola SH. ACC/AHA ...
... When citing this document, the American College of Cardiology and the American Heart Association recommend that the following format be used: Bonow RO, Carabello B, de Leon AC Jr, Edmunds LH Jr, Fedderly BJ, Freed MD, Gaasch WH, McKay CR, Nishimura RA, O’Gara PT, O’Rourke RA, Rahimtoola SH. ACC/AHA ...
ACC/AHA Guidelines for the Management of Patients With Valvular
... When citing this document, the American College of Cardiology and the American Heart Association recommend that the following format be used: Bonow RO, Carabello B, de Leon AC Jr, Edmunds LH Jr, Fedderly BJ, Freed MD, Gaasch WH, McKay CR, Nishimura RA, O’Gara PT, O’Rourke RA, Rahimtoola SH. ACC/AHA ...
... When citing this document, the American College of Cardiology and the American Heart Association recommend that the following format be used: Bonow RO, Carabello B, de Leon AC Jr, Edmunds LH Jr, Fedderly BJ, Freed MD, Gaasch WH, McKay CR, Nishimura RA, O’Gara PT, O’Rourke RA, Rahimtoola SH. ACC/AHA ...
Urinary Tract Infections Gram negative
... - ascending route of infection - organisms enter the urinary tract in a retrograde fashion via the urethra • Complicating factors such as catheters, nephrostomy tubes, surgery, urinary stones, etc - allow organisms to enter and persist in urinary tract - alter the typical spectrum of organisms - may ...
... - ascending route of infection - organisms enter the urinary tract in a retrograde fashion via the urethra • Complicating factors such as catheters, nephrostomy tubes, surgery, urinary stones, etc - allow organisms to enter and persist in urinary tract - alter the typical spectrum of organisms - may ...
Dengue hemorrhagic fever with special emphasis on
... manifestation of dengue virus infection Dengue virus infection can be asymptomatic or causes two forms of illness, DF and DHF [4,5] (Table 1), although the majority of dengue virus infections are asymptomatic. DF is a self-limited febrile illness [4,5]. After an incubation period of 2–7 days, a sudd ...
... manifestation of dengue virus infection Dengue virus infection can be asymptomatic or causes two forms of illness, DF and DHF [4,5] (Table 1), although the majority of dengue virus infections are asymptomatic. DF is a self-limited febrile illness [4,5]. After an incubation period of 2–7 days, a sudd ...
Progress in Autoimmune Diseases Research
... eases are rare, collectively they affect 14.7 to 23.5 million people in this country, and – for reasons unknown – their prevalence is rising. Since cures are not yet available for most autoimmune diseases, patients face a lifetime of illness and treatment. They often endure debilitating symptoms, lo ...
... eases are rare, collectively they affect 14.7 to 23.5 million people in this country, and – for reasons unknown – their prevalence is rising. Since cures are not yet available for most autoimmune diseases, patients face a lifetime of illness and treatment. They often endure debilitating symptoms, lo ...
Functional mitral regurgitation in patients with heart failure and
... Mitral regurgitation is a commonly encountered valvular lesion in modern clinical practice [1]. Mitral regurgitation can be further classified into organic (or primary) and functional (or secondary). Organic mitral regurgitation refers to regurgitant lesions resulting from disorders of the mitral va ...
... Mitral regurgitation is a commonly encountered valvular lesion in modern clinical practice [1]. Mitral regurgitation can be further classified into organic (or primary) and functional (or secondary). Organic mitral regurgitation refers to regurgitant lesions resulting from disorders of the mitral va ...
Immunological and Genetic Aspects of Narcolepsy
... to narcolepsy, and is found in 90% of narcolepsy cases. Nevertheless, the allele is quite common, ranging in frequency across ethnic groups from 12% in Japanese to 38% in African Americans, and is therefore not sufficient for the development of the disease. Furthermore, the association between narco ...
... to narcolepsy, and is found in 90% of narcolepsy cases. Nevertheless, the allele is quite common, ranging in frequency across ethnic groups from 12% in Japanese to 38% in African Americans, and is therefore not sufficient for the development of the disease. Furthermore, the association between narco ...
Document
... maturation. Additionally, the newborn foal monocyte-derived dendritic cells have been shown to respond to R. equi infection comparably with adult horse cells, with the expression of IL-12.53 Although TLR-mediated immune response to ligands has been implicated in immature immunity in neonates, dendri ...
... maturation. Additionally, the newborn foal monocyte-derived dendritic cells have been shown to respond to R. equi infection comparably with adult horse cells, with the expression of IL-12.53 Although TLR-mediated immune response to ligands has been implicated in immature immunity in neonates, dendri ...
Licentiate thesis from the Department of Immunology,
... Tuberculosis (TB) remains one of the world’s most serious infectious diseases. It is estimated that a third of the world’s population is latently infected and 8 million new cases are recorded each year. Although BCG vaccination triggers protective immune responses in the neonates, it confers protect ...
... Tuberculosis (TB) remains one of the world’s most serious infectious diseases. It is estimated that a third of the world’s population is latently infected and 8 million new cases are recorded each year. Although BCG vaccination triggers protective immune responses in the neonates, it confers protect ...
22 It`s hard to name a thinker more important to shaping
... Delbrück had offered to submit to the Proceedings of the National Academy of Sciences. “Do not make any changes in the text, but please leave it as it stands,” Jerne the postdoc requested on a note to one of the fathers of molecular biology. Delbrück added a comma and sent it off; it was published i ...
... Delbrück had offered to submit to the Proceedings of the National Academy of Sciences. “Do not make any changes in the text, but please leave it as it stands,” Jerne the postdoc requested on a note to one of the fathers of molecular biology. Delbrück added a comma and sent it off; it was published i ...
Rheumatic fever
Rheumatic fever, also known as acute rheumatic fever (ARF), is an inflammatory disease that can involve the heart, joints, skin, and brain. The disease typically develops two to four weeks after a throat infection. Signs and symptoms include fever, multiple painful joints, involuntary muscle movements, and a characteristic but uncommon non itchy rash known as erythema marginatum. The heart is involved in about half of cases. Permanent damage to the heart valves, known as rheumatic heart disease (RHD), usually only occurs after multiple attacks but may occasionally occur after a single case of ARF. The damaged valves may result in heart failure. The abnormal valves also increase the risk of the person developing atrial fibrillation and infection of the valves.Acute rheumatic fever may occur following an infection of the throat by the bacteria Streptococcus pyogenes. If it is untreated ARF occurs in up to three percent of people. The underlying mechanism is believed to involve the production of antibodies against a person's own tissues. Some people due to their genetics are more likely to get the disease when exposed to the bacteria than others. Other risk factors include malnutrition and poverty. Diagnosis of ARF is often based on the presence of signs and symptoms in combination with evidence of a recent streptococcal infection.Treating people who have strep throat with antibiotics, such as penicillin, decreases their risk of getting ARF. This often involves testing people with sore throats for the infection, which may not be available in the developing world. Other preventative measures include improved sanitation. In those with ARF and RHD prolonged periods of antibiotics are sometimes recommended. Gradual return to normal activities may occur following an attack. Once RHD develops, treatment is more difficult. Occasionally valve replacement surgery or repair is required. Otherwise complications are treated as per normal.Acute rheumatic fever occurs in about 325,000 children each year and about 18 million people currently have rheumatic heart disease. Those who get ARF are most often between the ages of 5 and 14, with 20% of first-time attacks occurring in adults. The disease is most common in the developing world and among indigenous peoples in the developed world. In 2013 it resulted in 275,000 deaths down from 374,000 deaths in 1990. Most deaths occur in the developing world where as many as 12.5% of people affected may die each year. Descriptions of the condition are believed to date back to at least the 5th century BCE in the writings of Hippocrates. The disease is so named because its symptoms are similar to those of some rheumatic disorders.