Supplementary Figure Legends (doc 28K)
... standard deviations. Significant P-values are indicated by asterisks (* P=0.03; ** P=0.003; *** P<0.001). (B) HLA-A2 molecule expression on the surfaces of MCF-7 and MDA-MB-231 cell lines. Immunofluorescence staining was performed using MA2.1 monoclonal antibody and analysed on BD LSR Flow Cytometer ...
... standard deviations. Significant P-values are indicated by asterisks (* P=0.03; ** P=0.003; *** P<0.001). (B) HLA-A2 molecule expression on the surfaces of MCF-7 and MDA-MB-231 cell lines. Immunofluorescence staining was performed using MA2.1 monoclonal antibody and analysed on BD LSR Flow Cytometer ...
Maxpar® Human Regulatory T Cell Phenotyping Panel Kit
... subset of CD4+ T helper (Th) cells important for the regulation of immune responses. Tregs are defined by expression of the transcription factor Foxp3. Additional Treg markers include constitutive expression of the high-affinity IL-2Rα chain (CD25) and cytotoxic T lymphocyte-associated antigen 4 (CT ...
... subset of CD4+ T helper (Th) cells important for the regulation of immune responses. Tregs are defined by expression of the transcription factor Foxp3. Additional Treg markers include constitutive expression of the high-affinity IL-2Rα chain (CD25) and cytotoxic T lymphocyte-associated antigen 4 (CT ...
immnity organ 3
... APC → Carry to Ag on MHCII, this antigen is exogenous Ag- & present it to Th. T helper carry CD4 for MHCII or carry Ag direct to B cells. N B APC → carry the antigen after engulfment, fragmentation to different epitopes. Then epitope exposed on surfaces of APC with MHCII. ...
... APC → Carry to Ag on MHCII, this antigen is exogenous Ag- & present it to Th. T helper carry CD4 for MHCII or carry Ag direct to B cells. N B APC → carry the antigen after engulfment, fragmentation to different epitopes. Then epitope exposed on surfaces of APC with MHCII. ...
2-immune system
... What are the cell types involved with immune responses? What are the important immunological tissues? ...
... What are the cell types involved with immune responses? What are the important immunological tissues? ...
Immune System Review Sheet
... 3. Describe the body’s first line of nonspecific defense, and give a few examples. 4. Describe the body’s second line of nonspecific defense, and give a few examples. ...
... 3. Describe the body’s first line of nonspecific defense, and give a few examples. 4. Describe the body’s second line of nonspecific defense, and give a few examples. ...
body defenses
... • Poor hygiene among patients and hospital staff contributes to the spread of pathogens in this way. ...
... • Poor hygiene among patients and hospital staff contributes to the spread of pathogens in this way. ...
Clues
... 6. A protein produced by most cells that interfere with virus production and tumor growth. 7. The organ that detects and responds to foreign substances in the blood , destroys worn out blood cells, and acts as a blood reservoir. 10. A non disease type antigen that many cause an excessive inflammatio ...
... 6. A protein produced by most cells that interfere with virus production and tumor growth. 7. The organ that detects and responds to foreign substances in the blood , destroys worn out blood cells, and acts as a blood reservoir. 10. A non disease type antigen that many cause an excessive inflammatio ...
Cell Signaling
... • Examples include ion channel receptors, G-protein –coupled receptors, and protein kinase receptors • End product of the signal transduction pathway is a change in gene expression, a change in protein activity, or apoptosis (cellular death) ...
... • Examples include ion channel receptors, G-protein –coupled receptors, and protein kinase receptors • End product of the signal transduction pathway is a change in gene expression, a change in protein activity, or apoptosis (cellular death) ...
Humoral Immune Response
... Antigen is “processed” by T lymphocytes and macrophages. Possess special receptors on surface. Termed “antigen presenter cell” APC. Antigen presented to B cell ...
... Antigen is “processed” by T lymphocytes and macrophages. Possess special receptors on surface. Termed “antigen presenter cell” APC. Antigen presented to B cell ...
PPT 23
... Frenkel (1947). Suspensions of the epithelial cells were prepared from the tongues of healthy cattle, maintained and infected in vitro. The Frenkel procedure was used for vaccine production for many years. ...
... Frenkel (1947). Suspensions of the epithelial cells were prepared from the tongues of healthy cattle, maintained and infected in vitro. The Frenkel procedure was used for vaccine production for many years. ...
Powerpoint Presentation: The Monoclonal Antibodies
... Diagnosing and identifying molecules • Preparations can be made to identify tissue types with a high degree of accuracy • The preparation of pregnancy testing kits using anti HCG antibody linked to a coloured indicator • The identification and localisation of molecules in cells or on the surface of ...
... Diagnosing and identifying molecules • Preparations can be made to identify tissue types with a high degree of accuracy • The preparation of pregnancy testing kits using anti HCG antibody linked to a coloured indicator • The identification and localisation of molecules in cells or on the surface of ...
adaptive immune system - Zanichelli online per la scuola
... encountered, “naïve” lymphocytes proliferate to produce clones of effector and memory cells. Secondary immune response: when antigen is encountered again, memory cells proliferate and launch an army of plasma cells and effector T cells. Because of immunological memory, exposure to many diseases prov ...
... encountered, “naïve” lymphocytes proliferate to produce clones of effector and memory cells. Secondary immune response: when antigen is encountered again, memory cells proliferate and launch an army of plasma cells and effector T cells. Because of immunological memory, exposure to many diseases prov ...
PowerPoint Presentation to accompany Life: The Science of
... Interleukin-1 (a cytokine) activates a TH cell. ...
... Interleukin-1 (a cytokine) activates a TH cell. ...
Vaccination and HIV
... through conjugation. Resistance is quickly spread through many bacteria. ...
... through conjugation. Resistance is quickly spread through many bacteria. ...
Monoclonal Antibodies Treatment for Various Diseases www
... antibodies will attach foreign substances called antigens and neutralize or destroy them. If our body is exposed to a bacteria or virus, then it will get rid of infection by producing antibodies. Antibodies are considered as the natural defensive substances. They are generally produced by the B cell ...
... antibodies will attach foreign substances called antigens and neutralize or destroy them. If our body is exposed to a bacteria or virus, then it will get rid of infection by producing antibodies. Antibodies are considered as the natural defensive substances. They are generally produced by the B cell ...
IMMUNE SYSTEM - Roslyn School
... Bacteria cause disease • Heterotrophic bacteria – obtain nutrients by secreting enzymes that break down complex organic structures and absorbing them ...
... Bacteria cause disease • Heterotrophic bacteria – obtain nutrients by secreting enzymes that break down complex organic structures and absorbing them ...
The Human Body Systems
... b) Antibodies are proteins that react with antigens (foreign molecules that have attacked the body) to deactivate them. (1) T Cells – Identify one kind of pathogen from another – (a) Over 10 million T Cells in your body, each able to recognize different types of proteins (Antigens) found on the cell ...
... b) Antibodies are proteins that react with antigens (foreign molecules that have attacked the body) to deactivate them. (1) T Cells – Identify one kind of pathogen from another – (a) Over 10 million T Cells in your body, each able to recognize different types of proteins (Antigens) found on the cell ...
Poster
... she sees them as foreign. Maternal B cells produce antibodies anti-HPA1a. The antibodies bind to the platelets and these antibody-coated platelets are then marked for destruction, leading to clotting disorder. Interestingly, mother responders are characterized by the expression of class II HLA DRB3* ...
... she sees them as foreign. Maternal B cells produce antibodies anti-HPA1a. The antibodies bind to the platelets and these antibody-coated platelets are then marked for destruction, leading to clotting disorder. Interestingly, mother responders are characterized by the expression of class II HLA DRB3* ...
Chapter 18 The Immune System
... An innate body defense in vertebrates caused by a release of histamine and other chemical alarm signals that trigger increased blood flow, a local increase in white blood cells, and fluid leakage from the blood. The resulting inflammatory response includes redness, heat, and swelling in the affected ...
... An innate body defense in vertebrates caused by a release of histamine and other chemical alarm signals that trigger increased blood flow, a local increase in white blood cells, and fluid leakage from the blood. The resulting inflammatory response includes redness, heat, and swelling in the affected ...
Polyclonal B cell response
Polyclonal B cell response is a natural mode of immune response exhibited by the adaptive immune system of mammals. It ensures that a single antigen is recognized and attacked through its overlapping parts, called epitopes, by multiple clones of B cell.In the course of normal immune response, parts of pathogens (e.g. bacteria) are recognized by the immune system as foreign (non-self), and eliminated or effectively neutralized to reduce their potential damage. Such a recognizable substance is called an antigen. The immune system may respond in multiple ways to an antigen; a key feature of this response is the production of antibodies by B cells (or B lymphocytes) involving an arm of the immune system known as humoral immunity. The antibodies are soluble and do not require direct cell-to-cell contact between the pathogen and the B-cell to function.Antigens can be large and complex substances, and any single antibody can only bind to a small, specific area on the antigen. Consequently, an effective immune response often involves the production of many different antibodies by many different B cells against the same antigen. Hence the term ""polyclonal"", which derives from the words poly, meaning many, and clones (""Klon""=Greek for sprout or twig); a clone is a group of cells arising from a common ""mother"" cell. The antibodies thus produced in a polyclonal response are known as polyclonal antibodies. The heterogeneous polyclonal antibodies are distinct from monoclonal antibody molecules, which are identical and react against a single epitope only, i.e., are more specific.Although the polyclonal response confers advantages on the immune system, in particular, greater probability of reacting against pathogens, it also increases chances of developing certain autoimmune diseases resulting from the reaction of the immune system against native molecules produced within the host.