Chapter 16: Hypersensitive Reactions
... resolves the infection within days • In some cases, the inflam response can have harmful effects – even result in death! -this type of IR is called ‘hypersensitivity’ or ‘allergy’ • Hypersensitive reactions develop during the course of either: – Humoral IR response or – Cell-mediated IR response ...
... resolves the infection within days • In some cases, the inflam response can have harmful effects – even result in death! -this type of IR is called ‘hypersensitivity’ or ‘allergy’ • Hypersensitive reactions develop during the course of either: – Humoral IR response or – Cell-mediated IR response ...
VOIES DE SIGNALISATION DES HAPTENES CHIMIQUES DANS
... association with protein. It is believed that in most instances the hapten-protein conjugate is recognised and internalised by dendritic cells (DC) that are found in the dermis and in the epidermis (Langerhans cells). These cells, under the regulation of cutaneous cytokines such as TNF- and IL-1 and ...
... association with protein. It is believed that in most instances the hapten-protein conjugate is recognised and internalised by dendritic cells (DC) that are found in the dermis and in the epidermis (Langerhans cells). These cells, under the regulation of cutaneous cytokines such as TNF- and IL-1 and ...
immune system
... macrophages. Bacterial lipopolysaccharide (LPS) is particularly effective in inducing fever Mechanism of action: Pyrogenes result in the production of prostaglandin E2-t (PGE2). PGE2 acts on the hypothalamus to increase the set point. Consequently, the body produces heat and decreases its dissipatio ...
... macrophages. Bacterial lipopolysaccharide (LPS) is particularly effective in inducing fever Mechanism of action: Pyrogenes result in the production of prostaglandin E2-t (PGE2). PGE2 acts on the hypothalamus to increase the set point. Consequently, the body produces heat and decreases its dissipatio ...
1: Prescott Atkinson, pediatric immunologist/allergist at Children`s
... trying to understand them, what causes them and decide how to prevent them from occurring and the best methods of treatment. We’re going to go over some basic information about how we think about these disorders, some different examples of them and how they’re generally treated. Immunologic hypersen ...
... trying to understand them, what causes them and decide how to prevent them from occurring and the best methods of treatment. We’re going to go over some basic information about how we think about these disorders, some different examples of them and how they’re generally treated. Immunologic hypersen ...
5.2. general texts on biological products
... Seed-lot system. A seed-lot system is a system according to which successive batches of a product are derived from the same master seed lot. For routine production, a working seed lot may be prepared from the master seed lot. The origin and the passage history of the master seed lot and the working ...
... Seed-lot system. A seed-lot system is a system according to which successive batches of a product are derived from the same master seed lot. For routine production, a working seed lot may be prepared from the master seed lot. The origin and the passage history of the master seed lot and the working ...
Supplementary Information (doc 417K)
... Motif analysis To count motifs in CBFβ-MYH11 binding sites we derived the weight matrix of different consensus binding sites for various proteins involved in hematopoiesis from Jaspar (http://jaspar.genereg.net/). All CBFβ-MYH11 binding sites were subsequently examined for the presence or absence of ...
... Motif analysis To count motifs in CBFβ-MYH11 binding sites we derived the weight matrix of different consensus binding sites for various proteins involved in hematopoiesis from Jaspar (http://jaspar.genereg.net/). All CBFβ-MYH11 binding sites were subsequently examined for the presence or absence of ...
- Wiley Online Library
... which were not enriched for L. major-specific T cells. The CD11c+, CD8 § –, F4/80–, and Langerin– DC that are colocalized with L. major antigen in our experiments are consistent with the antigen-transporting DC that collect antigen at the site of immunization, transport it to the draining LN, and pr ...
... which were not enriched for L. major-specific T cells. The CD11c+, CD8 § –, F4/80–, and Langerin– DC that are colocalized with L. major antigen in our experiments are consistent with the antigen-transporting DC that collect antigen at the site of immunization, transport it to the draining LN, and pr ...
ch_21_lecture_presentation_a
... Binds interferon from cell 1; interferon induces synthesis of protective proteins ...
... Binds interferon from cell 1; interferon induces synthesis of protective proteins ...
How HIV Causes AIDS: Is HIV an Inflammatory Disease?
... • Key is treating the underlying infection to decrease antigen load • Continue ART in all cases • Most cases are self-limited • However, CNS IRIS (crypto and PML) can be lethal and may require intensive management of ICP and/or steroids • Steroids can be used, but should be reserved for severe cases ...
... • Key is treating the underlying infection to decrease antigen load • Continue ART in all cases • Most cases are self-limited • However, CNS IRIS (crypto and PML) can be lethal and may require intensive management of ICP and/or steroids • Steroids can be used, but should be reserved for severe cases ...
Successful Plating Strategies
... be caused in part by overgrowth in the previous stage. If these problems exist, add a drop or two of Hybridoma Cloning Factor. Stepping the weaning process back to when the cells were growing well or using feeder cultures may help get the cells to the next stage (see Protocols 14 –17 for the prepara ...
... be caused in part by overgrowth in the previous stage. If these problems exist, add a drop or two of Hybridoma Cloning Factor. Stepping the weaning process back to when the cells were growing well or using feeder cultures may help get the cells to the next stage (see Protocols 14 –17 for the prepara ...
Cell Membrane
... Transcytosis • Endocytosis followed by exocytosis • Transports a substance rapidly through a cell • HIV crossing a cell layer Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. ...
... Transcytosis • Endocytosis followed by exocytosis • Transports a substance rapidly through a cell • HIV crossing a cell layer Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. ...
IMMUNE RESPONSES AGAINST MYCOBACTERIUM
... a robust concept for identification of TB targets; we were able to identify differential target recognition patterns in TB+ patients vs TB exposed health care workers. Comprehensive pattern recognition analysis using biologically relevant targets revealed that enzymes involved in M.tb lipid synthesi ...
... a robust concept for identification of TB targets; we were able to identify differential target recognition patterns in TB+ patients vs TB exposed health care workers. Comprehensive pattern recognition analysis using biologically relevant targets revealed that enzymes involved in M.tb lipid synthesi ...
4 slides pdf
... interactions between side chains in different regions. – results in domains, basic units of tertiary structure Quaternary structure: interactions between different polypeptide chains in proteins composed of more than one polypeptide ...
... interactions between side chains in different regions. – results in domains, basic units of tertiary structure Quaternary structure: interactions between different polypeptide chains in proteins composed of more than one polypeptide ...
ch_12_lecture_presentation
... When they present antigens, dendritic cells and macrophages activate T cells, which release chemicals © 2015 Pearson Education, Inc. ...
... When they present antigens, dendritic cells and macrophages activate T cells, which release chemicals © 2015 Pearson Education, Inc. ...
ppt
... Cell biology seeks to understand cellular processes in terms of chemical, physical reactions Student Learning Outcomes: A. To describe molecular composition of cells: Carbohydrates, lipids, nucleic acids, proteins Draw phospholipid structures, sugars, amino acid ...
... Cell biology seeks to understand cellular processes in terms of chemical, physical reactions Student Learning Outcomes: A. To describe molecular composition of cells: Carbohydrates, lipids, nucleic acids, proteins Draw phospholipid structures, sugars, amino acid ...
Glycobiology of the Immune Response, Volume 1253. Annals of the... Academy of Sciences Brochure
... Carbohydrates are ubiquitous, essential molecules, as important as nucleic acids and proteins yet less well understood. Mounting data demonstrate that microbial and mammalian glycans and their protein–binding partners (lectins) play central roles in all innate and adaptive immune responses. Indeed, ...
... Carbohydrates are ubiquitous, essential molecules, as important as nucleic acids and proteins yet less well understood. Mounting data demonstrate that microbial and mammalian glycans and their protein–binding partners (lectins) play central roles in all innate and adaptive immune responses. Indeed, ...
Save as PDF - Stiftung Tierärztliche Hochschule Hannover
... manifold. Often an immune suppression is discussed, which allows pathogens to spread out, generating infections and diseases. Little is known about the influence of anthropogenic stressors on the health status of marine mammals. To investigate this impact we analyse blood samples of harbour seals an ...
... manifold. Often an immune suppression is discussed, which allows pathogens to spread out, generating infections and diseases. Little is known about the influence of anthropogenic stressors on the health status of marine mammals. To investigate this impact we analyse blood samples of harbour seals an ...
(areolar) connective tissue
... - fibrous tissue with fewer cells (cells are mostly fibroblasts) - little ground substance - collagen fibers are bundles, without definite orientation - found in dermis, prostate, mammary glands, outer capsule of many organs 2. dense regularly arranged connective tissue (DRACT) - made of many fibers ...
... - fibrous tissue with fewer cells (cells are mostly fibroblasts) - little ground substance - collagen fibers are bundles, without definite orientation - found in dermis, prostate, mammary glands, outer capsule of many organs 2. dense regularly arranged connective tissue (DRACT) - made of many fibers ...
Carotenoid Action on the Immune Response
... roles in combating intracellular pathogens including viruses, bacteria and parasites. The Th2 cells are more effective in humoral immunity, i.e., they stimulate B cells to proliferate and produce antibodies against free-living microorganisms. Therefore, a normal immune response will require a balanc ...
... roles in combating intracellular pathogens including viruses, bacteria and parasites. The Th2 cells are more effective in humoral immunity, i.e., they stimulate B cells to proliferate and produce antibodies against free-living microorganisms. Therefore, a normal immune response will require a balanc ...
Polyclonal B cell response
Polyclonal B cell response is a natural mode of immune response exhibited by the adaptive immune system of mammals. It ensures that a single antigen is recognized and attacked through its overlapping parts, called epitopes, by multiple clones of B cell.In the course of normal immune response, parts of pathogens (e.g. bacteria) are recognized by the immune system as foreign (non-self), and eliminated or effectively neutralized to reduce their potential damage. Such a recognizable substance is called an antigen. The immune system may respond in multiple ways to an antigen; a key feature of this response is the production of antibodies by B cells (or B lymphocytes) involving an arm of the immune system known as humoral immunity. The antibodies are soluble and do not require direct cell-to-cell contact between the pathogen and the B-cell to function.Antigens can be large and complex substances, and any single antibody can only bind to a small, specific area on the antigen. Consequently, an effective immune response often involves the production of many different antibodies by many different B cells against the same antigen. Hence the term ""polyclonal"", which derives from the words poly, meaning many, and clones (""Klon""=Greek for sprout or twig); a clone is a group of cells arising from a common ""mother"" cell. The antibodies thus produced in a polyclonal response are known as polyclonal antibodies. The heterogeneous polyclonal antibodies are distinct from monoclonal antibody molecules, which are identical and react against a single epitope only, i.e., are more specific.Although the polyclonal response confers advantages on the immune system, in particular, greater probability of reacting against pathogens, it also increases chances of developing certain autoimmune diseases resulting from the reaction of the immune system against native molecules produced within the host.