The Lymphatic System
... Nonspecific response that is triggered whenever the body tissues are injured Occurs in response to physical trauma, intense heat, irritating chemicals as well as infection of viruses and ...
... Nonspecific response that is triggered whenever the body tissues are injured Occurs in response to physical trauma, intense heat, irritating chemicals as well as infection of viruses and ...
Blood- Chapter 18
... due to one’s immune system functioning to produce antibodies ______________ – acquired by transfer of serum from another animal produced by sensitized lymphocyte, or mother to fetus ...
... due to one’s immune system functioning to produce antibodies ______________ – acquired by transfer of serum from another animal produced by sensitized lymphocyte, or mother to fetus ...
Antigen
... site of infection or tumor formation • Recognize, attach & attack – secrete granules containing perforin that punch holes in target cell – secrete lymphotoxin that activates enzymes in the target cell causing its DNA to fragment – secrete gamma-interferon to activate phagocytic cells ...
... site of infection or tumor formation • Recognize, attach & attack – secrete granules containing perforin that punch holes in target cell – secrete lymphotoxin that activates enzymes in the target cell causing its DNA to fragment – secrete gamma-interferon to activate phagocytic cells ...
Anti-idiotypes and Immunity
... using killed, attenuated or subunit vaccines thus eliminates the dangers of using these pathogens ...
... using killed, attenuated or subunit vaccines thus eliminates the dangers of using these pathogens ...
Infectious disease
... causes paralysis and death. Health departments require pets be immunized and that infected animals be destroyed. Vaccine: drug made from altered microbes or their poisons injected or given by mouth to produce immunity. This was made to prevent illnesses in people; this trains the body’s immune sys ...
... causes paralysis and death. Health departments require pets be immunized and that infected animals be destroyed. Vaccine: drug made from altered microbes or their poisons injected or given by mouth to produce immunity. This was made to prevent illnesses in people; this trains the body’s immune sys ...
immune response lecture3
... Absence of Duffy antigen: Duffy antigen present on RBCs acts as a receptor for Plasmodium vivax. Its absence limits infection with this parasite. Haemoglobin S: its presence in RBCs provides immunity against Plasmodium falciparum because the parasite cannot feed on this type of haemoglobin. Deficien ...
... Absence of Duffy antigen: Duffy antigen present on RBCs acts as a receptor for Plasmodium vivax. Its absence limits infection with this parasite. Haemoglobin S: its presence in RBCs provides immunity against Plasmodium falciparum because the parasite cannot feed on this type of haemoglobin. Deficien ...
Immune system - Napa Valley College
... T cells When a helper T cell meets a APC cell it becomes activated – meaning it starts to make copies or clones of itself. These T cells leave the lymphatic system and circulate throughout the body. The helper T cells also activate cytotoxic T cells to also start making clones, and the helper T ...
... T cells When a helper T cell meets a APC cell it becomes activated – meaning it starts to make copies or clones of itself. These T cells leave the lymphatic system and circulate throughout the body. The helper T cells also activate cytotoxic T cells to also start making clones, and the helper T ...
Slide 1
... 1. Central lymphoid tissue: Irrelevant to immune response. a. develops earlier and perishes earlier. Makes up the central lymph organ, the thymus and bone marrow?. b. the site where the B lymphocytes (in bone marrow?) and T lymphocytes (in thymus) proliferate and differentiate into different types. ...
... 1. Central lymphoid tissue: Irrelevant to immune response. a. develops earlier and perishes earlier. Makes up the central lymph organ, the thymus and bone marrow?. b. the site where the B lymphocytes (in bone marrow?) and T lymphocytes (in thymus) proliferate and differentiate into different types. ...
PowerPoint
... – important role in innate immunity – kill malignant cells and cells infected with pathogens by releasing granzymes (cytotoxic enzymes) • Two ways of recognizing target cells – bind to antibodies which coat infected or malignant cells (antibodydependent cell-mediated cytotoxicity (ADCC) – recognizes ...
... – important role in innate immunity – kill malignant cells and cells infected with pathogens by releasing granzymes (cytotoxic enzymes) • Two ways of recognizing target cells – bind to antibodies which coat infected or malignant cells (antibodydependent cell-mediated cytotoxicity (ADCC) – recognizes ...
Document
... After getting chicken pox once, your body has antibodies for chicken pox stored in memory BCells. If the pathogen chicken pox attacks your body again, your immune system is ready and recognizes the antigen and attacks right away. ...
... After getting chicken pox once, your body has antibodies for chicken pox stored in memory BCells. If the pathogen chicken pox attacks your body again, your immune system is ready and recognizes the antigen and attacks right away. ...
Autoimmunity and Autoimmune Diseases
... • Previous attempts to classify them as T-cell and B-cell mediated are outdated • Involve Innate and Adaptive Components • Classified based on the effector mechanisms that appear to be most responsible for organ damage: – Autoantibodies – T-cells ...
... • Previous attempts to classify them as T-cell and B-cell mediated are outdated • Involve Innate and Adaptive Components • Classified based on the effector mechanisms that appear to be most responsible for organ damage: – Autoantibodies – T-cells ...
New cell for asthma: enter the myeloid
... cells described by Petersen et al expressed markers found on neutrophils, such as CD16, and also a neutrophil/myeloid progenitor marker CD177. The morphology shown in the paper for T2M cells resembles that of band-type neutrophils. Could ...
... cells described by Petersen et al expressed markers found on neutrophils, such as CD16, and also a neutrophil/myeloid progenitor marker CD177. The morphology shown in the paper for T2M cells resembles that of band-type neutrophils. Could ...
taking advantage of malnourished mice an animal model for
... Grifola, Pleurotus, Ganoderma, Agaricus and Flammulina. These mushrooms particularly have long been suggested to possess immunomodulatory effects5. Immunity is a very complex homeostatic system consisting of a network of interacting cells, tissues and organs. It allows the organism to exist within ...
... Grifola, Pleurotus, Ganoderma, Agaricus and Flammulina. These mushrooms particularly have long been suggested to possess immunomodulatory effects5. Immunity is a very complex homeostatic system consisting of a network of interacting cells, tissues and organs. It allows the organism to exist within ...
Diseases of the Immune System
... 10-20% circulating lymphocytes Lymph nodes, spleen, mucosa-associated lymphoid tissue (MALT) Recognize antigen via the antigen-binding component of the receptor complex IgM and IgD present on the surface of all mature naïve B cells Each B cell receptor has a unique antigen specificity Analysis of Ig ...
... 10-20% circulating lymphocytes Lymph nodes, spleen, mucosa-associated lymphoid tissue (MALT) Recognize antigen via the antigen-binding component of the receptor complex IgM and IgD present on the surface of all mature naïve B cells Each B cell receptor has a unique antigen specificity Analysis of Ig ...
Host Defenses
... linings of blood and lymph vessels and various organs and can only move by slowly rolling along the surface after being struck by other blood cells. Wandering macrophages are free to move throughout the blood and lymph systems. Once a macrophage phagocytizes a cell, it places some of that cell’s pro ...
... linings of blood and lymph vessels and various organs and can only move by slowly rolling along the surface after being struck by other blood cells. Wandering macrophages are free to move throughout the blood and lymph systems. Once a macrophage phagocytizes a cell, it places some of that cell’s pro ...
Aromatherapy and the Immune System
... percent of all lymphocytes. Once a also involved in the fight against they find the invader, they can use stem cell produces a descendant, the parasites. these enzymes to drill holes on its shell stromal cells of the bone marrow causing its insides to pour out. decide whether this cell will become a ...
... percent of all lymphocytes. Once a also involved in the fight against they find the invader, they can use stem cell produces a descendant, the parasites. these enzymes to drill holes on its shell stromal cells of the bone marrow causing its insides to pour out. decide whether this cell will become a ...
Fingerprinting Disease
... to preventive medicine seem like too little, too late. The immune system can reveal so much because the cells that make it up are so diverse. A healthy human has millions of unique immune cells; many circulate in the blood and play major roles in the body’s response to foreign invaders. Each of thes ...
... to preventive medicine seem like too little, too late. The immune system can reveal so much because the cells that make it up are so diverse. A healthy human has millions of unique immune cells; many circulate in the blood and play major roles in the body’s response to foreign invaders. Each of thes ...
IMMUNOPROPHYLAXIS: Vaccines and Immunotherapy 2014
... Gloucestershire county in the West of England. He observed that people who get cowpox often develop less severe disease and survive smallpox outbreaks. • Jenner inoculated a young boy (James Phipps) with material from hand sores of a milkmaid Sarah Nelmes. Six weeks later, after the boy recove ...
... Gloucestershire county in the West of England. He observed that people who get cowpox often develop less severe disease and survive smallpox outbreaks. • Jenner inoculated a young boy (James Phipps) with material from hand sores of a milkmaid Sarah Nelmes. Six weeks later, after the boy recove ...
Answers / Solutions
... 1. Acid base balance : It is the regulation of H+ ions in the body fluids. Any change in the pH value can cause alterations in the rate of chemical reactions. This can be maintained by buffering systems within the body. 2. Ionic balance : It is the regulation of ions like H, Na, Cl, K, Mg, HCO3 whic ...
... 1. Acid base balance : It is the regulation of H+ ions in the body fluids. Any change in the pH value can cause alterations in the rate of chemical reactions. This can be maintained by buffering systems within the body. 2. Ionic balance : It is the regulation of ions like H, Na, Cl, K, Mg, HCO3 whic ...
Vaccines
... Vaccines • Protect our body from contracting viruses and certain types of bacteria • Allow body to become immune to a specific pathogens – Example: Flu vaccine ...
... Vaccines • Protect our body from contracting viruses and certain types of bacteria • Allow body to become immune to a specific pathogens – Example: Flu vaccine ...
Cancer immunotherapy
Cancer immunotherapy (immuno-oncology) is the use of the immune system to treat cancer. Immunotherapies fall into three main groups: cellular, antibody and cytokine. They exploit the fact that cancer cells often have subtly different molecules on their surface that can be detected by the immune system. These molecules, known as cancer antigens, are most commonly proteins, but also include molecules such as carbohydrates. Immunotherapy is used to provoke the immune system into attacking the tumor cells by using these antigens as targets.Antibody therapies are the most successful immunotherapy, treating a wide range of cancers. Antibodies are proteins produced by the immune system that bind to a target antigen on the cell surface. In normal physiology the immune system uses them to fight pathogens. Each antibody is specific to one or a few proteins. Those that bind to cancer antigens are used to treat cancer. Cell surface receptors are common targets for antibody therapies and include the CD20, CD274, and CD279. Once bound to a cancer antigen, antibodies can induce antibody-dependent cell-mediated cytotoxicity, activate the complement system, or prevent a receptor from interacting with its ligand, all of which can lead to cell death. Multiple antibodies are approved to treat cancer, including Alemtuzumab, Ipilimumab, Nivolumab, Ofatumumab, and Rituximab.Cellular therapies, also known as cancer vaccines, usually involve the removal of immune cells from the blood or from a tumor. Immune cells specific for the tumor are activated, cultured and returned to the patient where the immune cells attack the cancer. Cell types that can be used in this way are natural killer cells, lymphokine-activated killer cells, cytotoxic T cells and dendritic cells. The only cell-based therapy approved in the US is Dendreon's Provenge, for the treatment of prostate cancer.Interleukin-2 and interferon-α are examples of cytokines, proteins that regulate and coordinate the behaviour of the immune system. They have the ability to enhance anti-tumor activity and thus can be used as cancer treatments. Interferon-α is used in the treatment of hairy-cell leukaemia, AIDS-related Kaposi's sarcoma, follicular lymphoma, chronic myeloid leukaemia and malignant melanoma. Interleukin-2 is used in the treatment of malignant melanoma and renal cell carcinoma.