Monday, June 1 Registration 15:00 – Keynote Lecture 17:00 – 18:20
... MECHANISMS BEHIND POTENT ACTIVITY OF CYTOKINE/mAB COMPLEXES Charles Surh TO BE ANNOUNCED Stephen Schoenberger RUNX/CBF-B IS A CRITICAL GATEKEEPER THAT DIRECTS THE TH1 AND TH17 DIFFERENTIATION Masato Kubo GATA3 PREVENTS TH2 CELL IFN-GAMMA PRODUCTION BY REPRESSING EOMESODERMIN EXPRESSION Ryoji Yagi ...
... MECHANISMS BEHIND POTENT ACTIVITY OF CYTOKINE/mAB COMPLEXES Charles Surh TO BE ANNOUNCED Stephen Schoenberger RUNX/CBF-B IS A CRITICAL GATEKEEPER THAT DIRECTS THE TH1 AND TH17 DIFFERENTIATION Masato Kubo GATA3 PREVENTS TH2 CELL IFN-GAMMA PRODUCTION BY REPRESSING EOMESODERMIN EXPRESSION Ryoji Yagi ...
I. Lymphatic System A. Lymphatic Vessels 1. Lymph Capillaries a
... a) Receives lymph from Right and Left Lumbar Trunks and Intestinal Trunk 2) As it ascends it receives lymph from Left Jugular, Left Subclavian, and Left Bronchomediastinal Trunks 3) Empties into Bloodstream at junction of Left Internal Jugular Vein and Left Subclavian Vein 4) Drains Left Upper Extre ...
... a) Receives lymph from Right and Left Lumbar Trunks and Intestinal Trunk 2) As it ascends it receives lymph from Left Jugular, Left Subclavian, and Left Bronchomediastinal Trunks 3) Empties into Bloodstream at junction of Left Internal Jugular Vein and Left Subclavian Vein 4) Drains Left Upper Extre ...
Document
... 1. Lai and Jin, (2009) and Lai et al., (2011) used mouse embryonic stem cells to produce the cells that had phenotype of thymic epithelial cells using FGF-7, FGF10 and BMP-4. 2. Inami et al., (2011) produced thymic epithelial progenitor cells (TEPCs) by phenotype – by culturing induced pluripotent s ...
... 1. Lai and Jin, (2009) and Lai et al., (2011) used mouse embryonic stem cells to produce the cells that had phenotype of thymic epithelial cells using FGF-7, FGF10 and BMP-4. 2. Inami et al., (2011) produced thymic epithelial progenitor cells (TEPCs) by phenotype – by culturing induced pluripotent s ...
1 - Intoduction to immunology 2015-16
... Hematopoietic cells leave the central cavity and drain to a central vein ...
... Hematopoietic cells leave the central cavity and drain to a central vein ...
Immune/Lympathic
... birth. The mother’s body recognizes the foreign antigens and makes antibodies to fight them off. • The first Rh+ fetus usually has no trouble, but any of the following fetuses (if Rh+) will cause a massive secondary reaction in the mother and the antibodies will kill off the fetuses blood. ...
... birth. The mother’s body recognizes the foreign antigens and makes antibodies to fight them off. • The first Rh+ fetus usually has no trouble, but any of the following fetuses (if Rh+) will cause a massive secondary reaction in the mother and the antibodies will kill off the fetuses blood. ...
Monday, June 1 Registration 15:00 – Keynote Lecture 17:00 – 18:20
... BONE MARROW Koji Tokoyoda IDENTIFICATION OF CD25+ T CELLS NATURALLY OCCURRING IL-17 PRODUCERS Kensuke Shibata ...
... BONE MARROW Koji Tokoyoda IDENTIFICATION OF CD25+ T CELLS NATURALLY OCCURRING IL-17 PRODUCERS Kensuke Shibata ...
Complexity and the Immune System
... But do we really need the network? • Genetic variation can lead to B and T cells that cover the entire range of pathogens, and each antibody hits on average one antigen • B cells differentiate into memory cells, which are able to quickly split into lots of effector cells and more memory cells • Aft ...
... But do we really need the network? • Genetic variation can lead to B and T cells that cover the entire range of pathogens, and each antibody hits on average one antigen • B cells differentiate into memory cells, which are able to quickly split into lots of effector cells and more memory cells • Aft ...
To the Admissions Committee
... Epigonal organ is the nurse shark bone marrow equivalent. Bone marrow contains pluripotent hematopoietic stem cells that give rise to cells circulating in the blood. It is the site of B lymphocyte development. Precursor B cells rearrange their Ig genes in the bone marrow, and after they successfully ...
... Epigonal organ is the nurse shark bone marrow equivalent. Bone marrow contains pluripotent hematopoietic stem cells that give rise to cells circulating in the blood. It is the site of B lymphocyte development. Precursor B cells rearrange their Ig genes in the bone marrow, and after they successfully ...
Lymphatic System
... B-cells and Antibody Immunity B lymphocytes give rise to plasma cells that create antibodies for specific antigens. The body has the ability to recognize its own cells and distinguish it from trespassers. Antibodies are proteins shaped like the antigen receptor and capable of combining with and neut ...
... B-cells and Antibody Immunity B lymphocytes give rise to plasma cells that create antibodies for specific antigens. The body has the ability to recognize its own cells and distinguish it from trespassers. Antibodies are proteins shaped like the antigen receptor and capable of combining with and neut ...
Lymphoid Tissues and Organs:
... -The newly arrived thymocytes acquire CD4,8, and TCR (Positive cells) -Cortical thymocytes are selected by their interaction to cortical epithelial cells (positive selection). -Medullary thymocytes are selected (negative selection). -Mature T cells are released into the circulation. ...
... -The newly arrived thymocytes acquire CD4,8, and TCR (Positive cells) -Cortical thymocytes are selected by their interaction to cortical epithelial cells (positive selection). -Medullary thymocytes are selected (negative selection). -Mature T cells are released into the circulation. ...
The Immune System - Blue Valley School District
... Inflammation In reaction to tissue damage or cell death mast cells release histamine which induces dilation in the surrounding capillaries and indirectly the four symptoms of inflammation: 1. Swelling 2. Reddness 3. Warmth 4. Pain ...
... Inflammation In reaction to tissue damage or cell death mast cells release histamine which induces dilation in the surrounding capillaries and indirectly the four symptoms of inflammation: 1. Swelling 2. Reddness 3. Warmth 4. Pain ...
Lymphatic system - Seattle Central
... – Activate immune system by stimulating lymphocyte proliferation ...
... – Activate immune system by stimulating lymphocyte proliferation ...
Autoimmunity 3rd yr
... Some self-antigens are sequestered in specialized tissues and may not be expressed in the thymus. These are not seen by the developing immune system – will not induce selftolerance. Exposure of T cells to these normally sequestered/tissue-specific self-antigens in the periphery results in their ...
... Some self-antigens are sequestered in specialized tissues and may not be expressed in the thymus. These are not seen by the developing immune system – will not induce selftolerance. Exposure of T cells to these normally sequestered/tissue-specific self-antigens in the periphery results in their ...
Exam 2
... MHC o What is haplotype? o Which MHC reacts with what population of T cells? o On what cells do you find Class I MHC? Class II MHC? o Antigen presentation – review both the cystolic and endocytic pathways ...
... MHC o What is haplotype? o Which MHC reacts with what population of T cells? o On what cells do you find Class I MHC? Class II MHC? o Antigen presentation – review both the cystolic and endocytic pathways ...
241.Autoimmunity
... Occurs when a virus or a bacterium posses antigenic determinants that are very similar or identical to normal host cell components Molecular mimicry may be the initiating step in a variety of autoimmune diseases. E.g. Rheumatoid fever occurs after streptococcal infection ...
... Occurs when a virus or a bacterium posses antigenic determinants that are very similar or identical to normal host cell components Molecular mimicry may be the initiating step in a variety of autoimmune diseases. E.g. Rheumatoid fever occurs after streptococcal infection ...
第九章 免疫系统
... It contains epithelioreticular cells (more) and T lymphocytes(less). T lymphocytes here are mature ones. ...
... It contains epithelioreticular cells (more) and T lymphocytes(less). T lymphocytes here are mature ones. ...
Lymphatic System - bushelman-hap
... and thymopoietin) that cause T lymphocytes to become immunocompetent (mature) • The capsule divides it into 2 lobes ...
... and thymopoietin) that cause T lymphocytes to become immunocompetent (mature) • The capsule divides it into 2 lobes ...
LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
... 4. Which one of the following cell type is least effective against extra cellular bacterial pathogen? a) B cells b) cytotoxic Tcells c) TNFγ d) macrophages 5. Immuno suppression is not induced by a) anti histamines b) removal of lymphoid tissue c)use of anti lymphocyte antibodies d) cytotoxic drugs ...
... 4. Which one of the following cell type is least effective against extra cellular bacterial pathogen? a) B cells b) cytotoxic Tcells c) TNFγ d) macrophages 5. Immuno suppression is not induced by a) anti histamines b) removal of lymphoid tissue c)use of anti lymphocyte antibodies d) cytotoxic drugs ...
Lymphatic Pre-Test
... 12) The specific foreign substances that an individual's immune system has the ability to recognize and resist is determined by: A) the total number of self-antigens at a given time B) individual exposure to the specific foreign substance C) individual genetic makeup D) the total number of macrophag ...
... 12) The specific foreign substances that an individual's immune system has the ability to recognize and resist is determined by: A) the total number of self-antigens at a given time B) individual exposure to the specific foreign substance C) individual genetic makeup D) the total number of macrophag ...
March 24 (PP)
... Negative selection eliminates self reactive lymphocytes Autoimmune diseases caused by body responding to self antigens MHC genes involved; genetically based ...
... Negative selection eliminates self reactive lymphocytes Autoimmune diseases caused by body responding to self antigens MHC genes involved; genetically based ...
Chapter 13: Lymphatics
... 63. Why does the medulla of the thymus stain lighter than the cortex? 64. What is the function of the blood-thymus barrier? 65. What specific types of lymphocytes leave the thymus? 66. What is the role of myofibroblasts in the capsule of the spleen? 67. What are PALS? 68. How can PALS be distinguish ...
... 63. Why does the medulla of the thymus stain lighter than the cortex? 64. What is the function of the blood-thymus barrier? 65. What specific types of lymphocytes leave the thymus? 66. What is the role of myofibroblasts in the capsule of the spleen? 67. What are PALS? 68. How can PALS be distinguish ...
Slide 1
... thymus and bone marrow?. b. the site where the B lymphocytes (in bone marrow?) and T lymphocytes (in thymus) proliferate and differentiate into different types. 2. Peripheral lymphoid tissue: a. develops later and retains forever. b. the site where immune cells perform their functions. Makes up of p ...
... thymus and bone marrow?. b. the site where the B lymphocytes (in bone marrow?) and T lymphocytes (in thymus) proliferate and differentiate into different types. 2. Peripheral lymphoid tissue: a. develops later and retains forever. b. the site where immune cells perform their functions. Makes up of p ...
Cells of Immune system
... granulocytes, macrophages, dendritic cells, and lymphocytes) arise from a single cell type. ...
... granulocytes, macrophages, dendritic cells, and lymphocytes) arise from a single cell type. ...
Thymus
The thymus is a specialized primary lymphoid organ of the immune system. Within the thymus, T cells or T lymphocytes mature. T cells are critical to the adaptive immune system, where the body adapts specifically to foreign invaders. The thymus is composed of two identical lobes and is located anatomically in the anterior superior mediastinum, in front of the heart and behind the sternum. Histologically, each lobe of the thymus can be divided into a central medulla and a peripheral cortex which is surrounded by an outer capsule. The cortex and medulla play different roles in the development of T-cells. Cells in the thymus can be divided into thymic stromal cells and cells of hematopoietic origin (derived from bone marrow resident hematopoietic stem cells). Developing T-cells are referred to as thymocytes and are of hematopoietic origin. Stromal cells include epithelial cells of the thymic cortex and medulla, and dendritic cells.The thymus provides an inductive environment for development of T cells from hematopoietic progenitor cells. In addition, thymic stromal cells allow for the selection of a functional and self-tolerant T cell repertoire. Therefore, one of the most important roles of the thymus is the induction of central tolerance.The thymus is largest and most active during the neonatal and pre-adolescent periods. By the early teens, the thymus begins to atrophy and thymic stroma is mostly replaced by adipose (fat) tissue. Nevertheless, residual T lymphopoiesis continues throughout adult life.