Course Objectives - Geisel School of Medicine
... Recognize the molecular mechanisms of control of the process and activation of viral genomes during reactivation. Explain the role of the immune system in the control of virus infection. Recognize current strategi ...
... Recognize the molecular mechanisms of control of the process and activation of viral genomes during reactivation. Explain the role of the immune system in the control of virus infection. Recognize current strategi ...
Blood Separation in Microfluidic Devices
... • White Blood Cells: ▫ Comprise most of the adaptive immune response ...
... • White Blood Cells: ▫ Comprise most of the adaptive immune response ...
Bacteria - mrswehri.com
... substances that are structurally similar to the actual disease-producing agents but that do not produce disease themselves. The first type of vaccine, contains chemically killed bacteria or other pathogenic organisms. The other type, such as the oral polio vaccine, contains weakened forms of liv ...
... substances that are structurally similar to the actual disease-producing agents but that do not produce disease themselves. The first type of vaccine, contains chemically killed bacteria or other pathogenic organisms. The other type, such as the oral polio vaccine, contains weakened forms of liv ...
2-Infectious diseases
... Microbes can evade immune responses either by varying antigens or by shedding antigens. - Streptococcus pneumonia exhibit antigenic variation ,their are at least 80 different serotypes of these microbes, each with different capsular polysaccharides. -Cercariae of Schistosoma mansoni shed their ant ...
... Microbes can evade immune responses either by varying antigens or by shedding antigens. - Streptococcus pneumonia exhibit antigenic variation ,their are at least 80 different serotypes of these microbes, each with different capsular polysaccharides. -Cercariae of Schistosoma mansoni shed their ant ...
Innate Immunity I
... Large lymphocytes that kill tumours (1973) NK cells in mice (1977) Require constitutive inhibition (1992) Mouse and humans use different families of inhibitory molecules ...
... Large lymphocytes that kill tumours (1973) NK cells in mice (1977) Require constitutive inhibition (1992) Mouse and humans use different families of inhibitory molecules ...
Hypersensitivities, Autoimmune Diseases, and Immune Deficiencies
... Response triggered by chemically modified skin proteins that the body regards as foreign Can happen when a hapten, such as the oil from poison ivy and related plants, binds to proteins on the skin ...
... Response triggered by chemically modified skin proteins that the body regards as foreign Can happen when a hapten, such as the oil from poison ivy and related plants, binds to proteins on the skin ...
Licensing opportunity Oral CXCR4 Antagonists Potential in
... large Volume of distribution, high clearance, terminal half-life of 11-16 hours, mixed-order pharmacokinetics (super-proportional increase in AUC at doses > 200 mg, significant reduction in drug exposure in the presence of food). ...
... large Volume of distribution, high clearance, terminal half-life of 11-16 hours, mixed-order pharmacokinetics (super-proportional increase in AUC at doses > 200 mg, significant reduction in drug exposure in the presence of food). ...
Life Science Reference Charts
... function similarly in all organisms. need energy, which animal and plant cells get from cellular respiration. make waste that moves across the cell and out the cell membrane. divide to cause growth and development of the organism. ALL organisms need energy, which animals get by eating and ...
... function similarly in all organisms. need energy, which animal and plant cells get from cellular respiration. make waste that moves across the cell and out the cell membrane. divide to cause growth and development of the organism. ALL organisms need energy, which animals get by eating and ...
Host Microbe Interations
... 2- M proteins found in strains of Streptococcus pyogenes also inactivate the C3b complement component. 3- Fc receptors found on the surface of Staphylococcus and Streptococcus bind to the fc region of an antibody preventing it from binding correctly! ...
... 2- M proteins found in strains of Streptococcus pyogenes also inactivate the C3b complement component. 3- Fc receptors found on the surface of Staphylococcus and Streptococcus bind to the fc region of an antibody preventing it from binding correctly! ...
File
... 9. Describe the characteristics of Type I hypersensitivity and provide 2-3 examples. Describe the characteristics of Type II hypersensititivy and provide 2-3 examples. What do the examples you provided affect? ...
... 9. Describe the characteristics of Type I hypersensitivity and provide 2-3 examples. Describe the characteristics of Type II hypersensititivy and provide 2-3 examples. What do the examples you provided affect? ...
Chapter 3 The Basic Structure of a Cell
... composed of one cell • Multicellularcomposed of many cells that may organize ...
... composed of one cell • Multicellularcomposed of many cells that may organize ...
novel AIDS DNA vaccine - HKU Li Ka Shing Faculty of Medicine
... • CD8+ T cells belong to a group of white blood cells known as cytotoxic lymphocytes or killer T cells. • They play a central role in cell-mediated immunity by killing HIV-infected cells and cancer cells. • The are well-known for their critical role of suppressing HIV replication and eliminating lat ...
... • CD8+ T cells belong to a group of white blood cells known as cytotoxic lymphocytes or killer T cells. • They play a central role in cell-mediated immunity by killing HIV-infected cells and cancer cells. • The are well-known for their critical role of suppressing HIV replication and eliminating lat ...
Respiratory System
... • A normal CFTR protein regulates the amount of chloride ions across the cell membrane of lung cells. • If the interior of the cell is too salty, water is drawn from lung mucus by osmosis, causing the mucus to become thick and sticky. ...
... • A normal CFTR protein regulates the amount of chloride ions across the cell membrane of lung cells. • If the interior of the cell is too salty, water is drawn from lung mucus by osmosis, causing the mucus to become thick and sticky. ...
Cardiovascular System
... 3. Antimicrobial proteins (a type of chemical defense) a) Interferon-3 kinds; stimulates the body cells to produce antiviral proteins. b) Complement - forms holes in plasma membranes of microbes, stimulates the release of histamine, and promotes phagocytosis. 4. Phagocytosis - Primarily by neutrophi ...
... 3. Antimicrobial proteins (a type of chemical defense) a) Interferon-3 kinds; stimulates the body cells to produce antiviral proteins. b) Complement - forms holes in plasma membranes of microbes, stimulates the release of histamine, and promotes phagocytosis. 4. Phagocytosis - Primarily by neutrophi ...
Regulation NERVOUS CONTROL CHEMICAL CONTROL I. How
... which secrete them into the ______________; this transports the hormone to a _________________ which will react a certain way hormones can either stimulate ________ or inhibit __________ a reaction ...
... which secrete them into the ______________; this transports the hormone to a _________________ which will react a certain way hormones can either stimulate ________ or inhibit __________ a reaction ...
RESPIRATORY SYSTEM
... phagocytosis and disposal of antigens reaching the alveoli. Bacteria and viruses are easily phagocytosed and degraded Indigested inert particles as carbon remain in macrophages for a long time and are deposited in islands of collagen (scar tissue). Heavy exposure to asbestos, coal and other indu ...
... phagocytosis and disposal of antigens reaching the alveoli. Bacteria and viruses are easily phagocytosed and degraded Indigested inert particles as carbon remain in macrophages for a long time and are deposited in islands of collagen (scar tissue). Heavy exposure to asbestos, coal and other indu ...
Towards T-cell based immunotherapy for DIPG Diffuse Intrinsic
... pressing need for novel therapeutic strategies. Cell-based immunotherapy provides a radically new approach. Here, patient derived T-cells are grafted with the required specificity so that they can bear their destructive potential on tumour cells while leaving healthy tissue unharmed. This can be ach ...
... pressing need for novel therapeutic strategies. Cell-based immunotherapy provides a radically new approach. Here, patient derived T-cells are grafted with the required specificity so that they can bear their destructive potential on tumour cells while leaving healthy tissue unharmed. This can be ach ...
ANTIBODY IMMUNE RESPONSE
... Physiologic – maintenance of immune – homeostasis (damaged cells). Low concentration, low affinity, polyspecifity, domination of IgM isotype. The concentration increases with age. Pathologic – high concentration, high-affinity IgG, IgA. Questionable participation of IgG in tissue damage. Autoimmune ...
... Physiologic – maintenance of immune – homeostasis (damaged cells). Low concentration, low affinity, polyspecifity, domination of IgM isotype. The concentration increases with age. Pathologic – high concentration, high-affinity IgG, IgA. Questionable participation of IgG in tissue damage. Autoimmune ...
Activated Helper T cells
... must present an antigen and a protein key to make doubly sure correct information is transferred to the Helper T cells. Macrophages use the Antigen Template Card to make an antigen out of pipe cleaner. Attach the pipe cleaner antigen to the Helper T Character Badge. But that’s not all – there must a ...
... must present an antigen and a protein key to make doubly sure correct information is transferred to the Helper T cells. Macrophages use the Antigen Template Card to make an antigen out of pipe cleaner. Attach the pipe cleaner antigen to the Helper T Character Badge. But that’s not all – there must a ...
Monoclonal antibodies
... ADCC is the least understood of the three mechanisms, it is mediated by either NK cells or CTL. The action of ADCC is dependant on the recognition of the objective cell by antibodies attached on the surface of the effector cell (terminally differentiated leukocyte). This process is part of the adapt ...
... ADCC is the least understood of the three mechanisms, it is mediated by either NK cells or CTL. The action of ADCC is dependant on the recognition of the objective cell by antibodies attached on the surface of the effector cell (terminally differentiated leukocyte). This process is part of the adapt ...
