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... maternal zinc deficiency, induces persistent cellular immune deficiency (Meadows et al, 1981). Altogether, these observations suggest that a moderate zinc deficiency occur- ...
... maternal zinc deficiency, induces persistent cellular immune deficiency (Meadows et al, 1981). Altogether, these observations suggest that a moderate zinc deficiency occur- ...
Consumption of Rice Bran Increases Mucosal
... Changes in the gut microbiota have been shown to significantly affect the mucosal immune system,21 most notably through the increased production and secretion of immunoglobulin A (IgA).22,23 For example, mice administered oral Lactobacillus acidophilus were shown to have increased production of IgA ...
... Changes in the gut microbiota have been shown to significantly affect the mucosal immune system,21 most notably through the increased production and secretion of immunoglobulin A (IgA).22,23 For example, mice administered oral Lactobacillus acidophilus were shown to have increased production of IgA ...
Lymph formation, composition and circulation
... states. A proteome significantly enriched in protease inhibitors and proteins related to innate immunity was observed. Human lymph proteome coverage has recently expanded as well (11, 13), confirming findings from animal models. Analyses of matched plasma and lymph from trauma patients resulted in t ...
... states. A proteome significantly enriched in protease inhibitors and proteins related to innate immunity was observed. Human lymph proteome coverage has recently expanded as well (11, 13), confirming findings from animal models. Analyses of matched plasma and lymph from trauma patients resulted in t ...
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... recognized by distinct receptors. The effector responses triggered lead to a chronic tissue inflammation. DsDNA autoantibodies are the most studied as well as the first in being characterized for its pathogenic role in Lupus nephritis. However, others are of growing interest since they have been ass ...
... recognized by distinct receptors. The effector responses triggered lead to a chronic tissue inflammation. DsDNA autoantibodies are the most studied as well as the first in being characterized for its pathogenic role in Lupus nephritis. However, others are of growing interest since they have been ass ...
Characterization of thymic hyperplasia associated with autoimmune
... Autoimmune myasthenia gravis (MG) is a muscular disease mediated by autoantibodies, mainly directed against the acetylcholine receptor (AChR). The pathogenic antibodies are especially produced in the thymus, which is often characterized by a hyperplasia with germinal centers. Recent studies demonstr ...
... Autoimmune myasthenia gravis (MG) is a muscular disease mediated by autoantibodies, mainly directed against the acetylcholine receptor (AChR). The pathogenic antibodies are especially produced in the thymus, which is often characterized by a hyperplasia with germinal centers. Recent studies demonstr ...
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... PI3P-binding effectors. In the second step, ubiquitin-like conjugation systems play an important role in regulating vesicle elongation and completion. There are two systems: the Atg16-Atg12-Atg5 complex controls the curvature of the growing membrane; and cleavage of the microtubule associated protei ...
... PI3P-binding effectors. In the second step, ubiquitin-like conjugation systems play an important role in regulating vesicle elongation and completion. There are two systems: the Atg16-Atg12-Atg5 complex controls the curvature of the growing membrane; and cleavage of the microtubule associated protei ...
Colonic microbiota can promote rapid local improvement of
... the adaptive immune system. This can occur via bacterial activation in the absence of host metabolism and/or local mucosal metabolism of TG, which may avoid the requirement for high concentrations of thioGTP in the systemic circulation for its action. Thus, local delivery of TG to the intestinal sit ...
... the adaptive immune system. This can occur via bacterial activation in the absence of host metabolism and/or local mucosal metabolism of TG, which may avoid the requirement for high concentrations of thioGTP in the systemic circulation for its action. Thus, local delivery of TG to the intestinal sit ...
UNIVERSIDAD DE MURCIA FACULTAD DE VETERINARIA In vivo
... The general aim of this thesis will be the evaluation of the swine immune response against PRRSV infection in the swine target cells and organs, paying special atention to the PRRSV ability to modulate the IIR and in consequence the AIR. First. Considering the central importance of MØ for PRRS patho ...
... The general aim of this thesis will be the evaluation of the swine immune response against PRRSV infection in the swine target cells and organs, paying special atention to the PRRSV ability to modulate the IIR and in consequence the AIR. First. Considering the central importance of MØ for PRRS patho ...
Monocytes high Differentiation of Ly-6C from the CCR2
... CCR2 mediates an increase in the frequency of Ly-6Chigh monocytes but not pre-DC within peripheral blood of mice with cryptococcal lung infection Our previous study demonstrated the accumulation of large numbers of DC in the lungs of CCR2⫹/⫹ mice, but not of CCR2⫺/⫺ mice, infected with C. neoformans ...
... CCR2 mediates an increase in the frequency of Ly-6Chigh monocytes but not pre-DC within peripheral blood of mice with cryptococcal lung infection Our previous study demonstrated the accumulation of large numbers of DC in the lungs of CCR2⫹/⫹ mice, but not of CCR2⫺/⫺ mice, infected with C. neoformans ...
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... antigen presentation pathways used by immature and mature DCs to present antigens from whole HIV-‐1 particles and the first project focused on this topic. In the second project we studied the initial ...
... antigen presentation pathways used by immature and mature DCs to present antigens from whole HIV-‐1 particles and the first project focused on this topic. In the second project we studied the initial ...
Lymphocytic hypophysitis: a rare or underestimated disease?
... Lymphocytic hypophysitis (LYH) is an uncommon autoimmune disease in which the pituitary gland is infiltrated by lymphocytes, plasma cells and macrophages and its function is usually impaired. It has to be suspected in pregnant women and in women with recent delivery presenting with hyperprolactinemi ...
... Lymphocytic hypophysitis (LYH) is an uncommon autoimmune disease in which the pituitary gland is infiltrated by lymphocytes, plasma cells and macrophages and its function is usually impaired. It has to be suspected in pregnant women and in women with recent delivery presenting with hyperprolactinemi ...
... molecules by themselves can seldom produce specific circulating antibodies. However, many small molecules may change the antigenic properties of a larger molecule, i.e. a protein, when covalently coupled to it (haptens). The resulting antibodies are partially directed against the small molecule. Imm ...
Lymph Glands (lymphoglandulae)
... After initial maturation in the primary immune organs, "virgin" B and T lymphocytes are released into the peripheral blood and home to specific sites within the lymph node (and the other secondary organs), controlled by incompletely understood homing receptors. The sites of B cell homing include: 1. ...
... After initial maturation in the primary immune organs, "virgin" B and T lymphocytes are released into the peripheral blood and home to specific sites within the lymph node (and the other secondary organs), controlled by incompletely understood homing receptors. The sites of B cell homing include: 1. ...
Spatial and temporal regulation of cytokine expression in Type 2
... allergic inflammation. Studies of the cell types and signalling pathways that mediate Type 2 immune responses have been previously undertaken with the goals of efficient development of vaccines against helminths, and identification of pathways that can be inhibited to decrease the damage caused by a ...
... allergic inflammation. Studies of the cell types and signalling pathways that mediate Type 2 immune responses have been previously undertaken with the goals of efficient development of vaccines against helminths, and identification of pathways that can be inhibited to decrease the damage caused by a ...
Extracellular milieu grossly alters pathogen
... Background: Considerably divergent data have been published from attempts to model the E. coli vs. S. aureus specific immune reaction of the udder using primary cultures of bovine mammary epithelial cells from cows (pbMEC). Some groups reported a swift, strong and transient inflammatory response aga ...
... Background: Considerably divergent data have been published from attempts to model the E. coli vs. S. aureus specific immune reaction of the udder using primary cultures of bovine mammary epithelial cells from cows (pbMEC). Some groups reported a swift, strong and transient inflammatory response aga ...
Bacterial lipopolysaccharide stimulates bovine neutrophil production
... preparation. On a per cell basis the monocytes in the previous study [8] produced far more molecules of cytokines than the PMN in our study. However, during mastitis PMN far outnumber macrophages by several orders of magnitude, and can therefore be major sources of cytokines like TNF-α. It was recen ...
... preparation. On a per cell basis the monocytes in the previous study [8] produced far more molecules of cytokines than the PMN in our study. However, during mastitis PMN far outnumber macrophages by several orders of magnitude, and can therefore be major sources of cytokines like TNF-α. It was recen ...
Characteristics of Peptide
... MHC molecules display peptides derived from microbes that are inside host cells MHC-restricted T cells recognize cell-associated microbes. They are the mediators of immunity to intracellular microbes. ...
... MHC molecules display peptides derived from microbes that are inside host cells MHC-restricted T cells recognize cell-associated microbes. They are the mediators of immunity to intracellular microbes. ...
Recent progress in vaccines
... neutralization of factors such as adhesins or enzymes which are a critical step for infection, or by inhibiting fungal escape from host immunity, or fungal growth or even directly killing the fungus [15,33,34]. Recently, specific antibodies to Cryptococcus neoformans were shown to directly modula ...
... neutralization of factors such as adhesins or enzymes which are a critical step for infection, or by inhibiting fungal escape from host immunity, or fungal growth or even directly killing the fungus [15,33,34]. Recently, specific antibodies to Cryptococcus neoformans were shown to directly modula ...
case report measles-mumps-rubella vaccination induced
... in a faster increase in platelet counts. Intravenous immunoglobulin, which blocks Fc-receptors on the macrophages of the reticuloendothelial system, is also the first line treatment for ITP in an emergency setting and proves effective when used at a high dose of 1-2 g/kg (Labarque and Van Geet, 2014 ...
... in a faster increase in platelet counts. Intravenous immunoglobulin, which blocks Fc-receptors on the macrophages of the reticuloendothelial system, is also the first line treatment for ITP in an emergency setting and proves effective when used at a high dose of 1-2 g/kg (Labarque and Van Geet, 2014 ...