Regulated MIP-3/CCL20 production by human intestinal epithelium
... that intestinal epithelium may also have the capacity to play a role in signaling host adaptive immunity. The CC chemokine macrophage inflammatory protein (MIP)-3␣/CCL20 is chemotactic for immature dendritic cells and CD45RO⫹ T cells that are important components of the host adaptive immune system. ...
... that intestinal epithelium may also have the capacity to play a role in signaling host adaptive immunity. The CC chemokine macrophage inflammatory protein (MIP)-3␣/CCL20 is chemotactic for immature dendritic cells and CD45RO⫹ T cells that are important components of the host adaptive immune system. ...
Palifermin in allogeneic HSCT: many questions remain
... expected protective effects of KGF. Although no clear differences exist in the immune reconstitution after exposure to CsA and MTX, combining the two drugs results in more toxic complications than are seen with either alone.8 Also the timing of palifermin is important for both the intestinal and thy ...
... expected protective effects of KGF. Although no clear differences exist in the immune reconstitution after exposure to CsA and MTX, combining the two drugs results in more toxic complications than are seen with either alone.8 Also the timing of palifermin is important for both the intestinal and thy ...
Animal Roles inMedical Discoveries Nobel Prizes for Medicine
... Nerve growth factor and epidermal growth factor Discovery of the genetic principle for generation of antibody diversity Discoveries of important principles for drug treatment Cellular origin of retroviral oncogenes Organ transplantation techniques Chemical communication between cells Discoverie ...
... Nerve growth factor and epidermal growth factor Discovery of the genetic principle for generation of antibody diversity Discoveries of important principles for drug treatment Cellular origin of retroviral oncogenes Organ transplantation techniques Chemical communication between cells Discoverie ...
Leukemia 2011 June
... CLL symptoms usually develop over time. Early in the course of the disease, CLL often has little effect on a person’s well-being. Some people with CLL do not have any symptoms. The disease may be suspected because of abnormal results from blood tests that were ordered either as part of an annual phy ...
... CLL symptoms usually develop over time. Early in the course of the disease, CLL often has little effect on a person’s well-being. Some people with CLL do not have any symptoms. The disease may be suspected because of abnormal results from blood tests that were ordered either as part of an annual phy ...
CD8 -Mediated Survival and Differentiation of CD8 Memory T Cell
... CD8⫹ splenocytes isolated from transgenic mice expressing the P14 TCR (specific for the LCMV GP33-41 epitope presented by H-2Db) were transferred into nontransgenic naı̈ve recipient mice. These animals were then infected with LCMV and analyzed at various times after infection. At day 8, a subset of ...
... CD8⫹ splenocytes isolated from transgenic mice expressing the P14 TCR (specific for the LCMV GP33-41 epitope presented by H-2Db) were transferred into nontransgenic naı̈ve recipient mice. These animals were then infected with LCMV and analyzed at various times after infection. At day 8, a subset of ...
Human perinatal immunity in physiological conditions and during
... gastrointestinal tract, and skin are exposed to amniotic fluid during pregnancy and are probable targets of infection and subsequent inflammation during pregnancy. We found a large number of studies focusing on prenatal infection and the host response. Intrauterine infection and fetal immune respons ...
... gastrointestinal tract, and skin are exposed to amniotic fluid during pregnancy and are probable targets of infection and subsequent inflammation during pregnancy. We found a large number of studies focusing on prenatal infection and the host response. Intrauterine infection and fetal immune respons ...
... and a modulatory effect on immune response, as well as antiviral activity [2]. Currently, interferon is divided into three subtypes: α-, β- and γ-interferon [3]. All three subtypes have been synthesized and used clinically against chronic active viral hepatitis [4], malignancies [5], or acquired imm ...
JCV-specific T-cells producing IFN-gamma are differently associated
... frequency of JCV-specific T-cells was not associated with the onset of PML in LTR. Despite the small sample size and the lack of an LTRPML group, our results may suggest different immunological mechanisms able to drive a protective immune response in HIV and LTR. Several immunological mechanisms can ...
... frequency of JCV-specific T-cells was not associated with the onset of PML in LTR. Despite the small sample size and the lack of an LTRPML group, our results may suggest different immunological mechanisms able to drive a protective immune response in HIV and LTR. Several immunological mechanisms can ...
IgG plasma cells display a unique spectrum of
... plasma cells observed in the cervical lymph nodes of E/P⫺/⫺ mice11 prompted us to investigate in detail the cellular composition of these lymph nodes. Total cell numbers from the E/P⫺/⫺ cervical lymph nodes were greatly increased compared to wild-type; mean ⫾ SD was 54 ⫻ 106 ⫾ 19.9 ⫻ 106 (n ⫽ 86 mic ...
... plasma cells observed in the cervical lymph nodes of E/P⫺/⫺ mice11 prompted us to investigate in detail the cellular composition of these lymph nodes. Total cell numbers from the E/P⫺/⫺ cervical lymph nodes were greatly increased compared to wild-type; mean ⫾ SD was 54 ⫻ 106 ⫾ 19.9 ⫻ 106 (n ⫽ 86 mic ...
cystic fibrosis lecture
... foreign particles 2. airway surface liquid (ASL) - provides microenvironment for beating cilia to clear mucus layer with assistance of coughing (ASL: rich broth of proteases/antiproteases, antibiotics, antibodies, and oxidant/antioxidants backed by cellular immune mechanisms) Defensins: small peptid ...
... foreign particles 2. airway surface liquid (ASL) - provides microenvironment for beating cilia to clear mucus layer with assistance of coughing (ASL: rich broth of proteases/antiproteases, antibiotics, antibodies, and oxidant/antioxidants backed by cellular immune mechanisms) Defensins: small peptid ...
PDF
... Strains. Not all aggregations result in chimaeric offspring: in those which are chimaeric, the proportions of cells derived from each strain may vary between mice and between tissues in a single mouse. For many studies with these mice, it would be useful to be able to distinguish the two cell popula ...
... Strains. Not all aggregations result in chimaeric offspring: in those which are chimaeric, the proportions of cells derived from each strain may vary between mice and between tissues in a single mouse. For many studies with these mice, it would be useful to be able to distinguish the two cell popula ...
Can the Hair Follicle Become a Model for Studying Selected
... Michael Kinori,1,2 Jennifer E. Kloepper,2 and Ralf Paus2,3 Immune privilege (IP) is important in maintaining ocular health. Understanding the mechanism underlying this dynamic state would assist in treating inflammatory eye diseases. Despite substantial progress in defining eye IP mechanisms, becaue ...
... Michael Kinori,1,2 Jennifer E. Kloepper,2 and Ralf Paus2,3 Immune privilege (IP) is important in maintaining ocular health. Understanding the mechanism underlying this dynamic state would assist in treating inflammatory eye diseases. Despite substantial progress in defining eye IP mechanisms, becaue ...
Cell-Mediated Immunity to Bordetella pertussis: Role of Thl
... pertussis. We found that nude mice, which are deficient in T cells, developed a persistent infection and failed to clear the bacteria after aerosol inoculation. In contrast, normal adult nonimmune mice cleared a respiratory infection approximately 35 days after challenge. Before bacterial clearance, ...
... pertussis. We found that nude mice, which are deficient in T cells, developed a persistent infection and failed to clear the bacteria after aerosol inoculation. In contrast, normal adult nonimmune mice cleared a respiratory infection approximately 35 days after challenge. Before bacterial clearance, ...
Lecture / notes (updated)
... Acquired Immunity Two kinds of immune response: Humoral Defends against toxins or pathogens outside of cells Cell-mediated or cytotoxic Destroys infected cells, cancer cells, and transplanted cells ...
... Acquired Immunity Two kinds of immune response: Humoral Defends against toxins or pathogens outside of cells Cell-mediated or cytotoxic Destroys infected cells, cancer cells, and transplanted cells ...
the animal body: introduction tostructure and function
... is a reservoir of salts and fluid. Together with adipose tissue, it forms the subcutaneous layer that attaches the skin to muscles and other structures beneath. The matrix is gel-like and contains all three fiber types, mast cells, fibroblasts and macrophages. 2. Dense connective tissue is found in ...
... is a reservoir of salts and fluid. Together with adipose tissue, it forms the subcutaneous layer that attaches the skin to muscles and other structures beneath. The matrix is gel-like and contains all three fiber types, mast cells, fibroblasts and macrophages. 2. Dense connective tissue is found in ...
Optimisation and parallelisation strategies for Monte Carlo simulation of HIV Infection
... responsible for phagocytosis of pathogens, dead cells and cellular debris, Cytotoxic T Cells and Helper T Cells, type of white blood cell or leukocyte which has on their surface antigen receptors that can bind to fragments of antigens, Plasma B cells secrete antibodies which effect the destruction ...
... responsible for phagocytosis of pathogens, dead cells and cellular debris, Cytotoxic T Cells and Helper T Cells, type of white blood cell or leukocyte which has on their surface antigen receptors that can bind to fragments of antigens, Plasma B cells secrete antibodies which effect the destruction ...
Document
... 2 category:Exogenous superantigen eg.Staphylococcus aureus enterotoxin A-E Endogenous superantigen eg. mouse mammary tumor virus protein 3 difference with common antigen： 1）low dose, but strong response 2）not constraint by MHC 3）recognition is not specific，and procession and presentation is not requ ...
... 2 category:Exogenous superantigen eg.Staphylococcus aureus enterotoxin A-E Endogenous superantigen eg. mouse mammary tumor virus protein 3 difference with common antigen： 1）low dose, but strong response 2）not constraint by MHC 3）recognition is not specific，and procession and presentation is not requ ...
WK11-RevApopt.
... -eliminate and phagocytose cells in an orderly fashion. -phosphatidylserine (PS) receptor on phagocytes increases anti-inflammatory cytokines TGF-beta and IL-10. -needed for embryogenesis, immune system maintenance. ...
... -eliminate and phagocytose cells in an orderly fashion. -phosphatidylserine (PS) receptor on phagocytes increases anti-inflammatory cytokines TGF-beta and IL-10. -needed for embryogenesis, immune system maintenance. ...
Module 5 Study Notes
... When the bee needs to have sugar the whole proventriculus gapes open and an amount of nectar is allowed through to the ventriculus, where the food is subjected to several enzymes which break it down into molecules small enough to be passed through the gut wall into the hymolympth. The bee appears to ...
... When the bee needs to have sugar the whole proventriculus gapes open and an amount of nectar is allowed through to the ventriculus, where the food is subjected to several enzymes which break it down into molecules small enough to be passed through the gut wall into the hymolympth. The bee appears to ...
Basophils
... Basophils and mast cells have long been implicated in the pathogenesis of allergic disease as high levels of mediators common to both cell types are found in tissue locations relevant to allergic diseases. Basophils are also a source of the major Th2-driving cytokine, IL-4, early in immune responses ...
... Basophils and mast cells have long been implicated in the pathogenesis of allergic disease as high levels of mediators common to both cell types are found in tissue locations relevant to allergic diseases. Basophils are also a source of the major Th2-driving cytokine, IL-4, early in immune responses ...