SITC 2015 Special Edition Immune Monitor – November 2015
... The Society for Immunotherapy of Cancer’s 30th Anniversary Award Ceremony celebrated the current and future leaders in the cancer immunotherapy field. The award winners were recognized for seeking to propel the field forward and build a solid foundation for future advances and soon, a cure. While th ...
... The Society for Immunotherapy of Cancer’s 30th Anniversary Award Ceremony celebrated the current and future leaders in the cancer immunotherapy field. The award winners were recognized for seeking to propel the field forward and build a solid foundation for future advances and soon, a cure. While th ...
reviews
... Defining the molecular and cellular mechanisms that regulate immunological hyporesponsiveness is an area of intense research. Recent studies in which various functional capacities of IECs have been targeted, either by the generation of bone-marrow chimaeras or by celllineage-specific deletion, have ...
... Defining the molecular and cellular mechanisms that regulate immunological hyporesponsiveness is an area of intense research. Recent studies in which various functional capacities of IECs have been targeted, either by the generation of bone-marrow chimaeras or by celllineage-specific deletion, have ...
File
... generated. The first cells must have evolved from non-living structures 4 billion years ago, but the development of “life” took place gradually over millions of years, so there was no definable first cell. ...
... generated. The first cells must have evolved from non-living structures 4 billion years ago, but the development of “life” took place gradually over millions of years, so there was no definable first cell. ...
Dendritic cells in Leishmania infection
... bone marrow-derived (BMD) Leishmania-infected macrophages and was selectively observed in infected cells [14]. In contrast, DCs are the main source of IL-12 in early Leishmania infection. In fact, murine C57BL/6 skin-derived DCs were recognised as the main source of IL-12p40 immediately after dermot ...
... bone marrow-derived (BMD) Leishmania-infected macrophages and was selectively observed in infected cells [14]. In contrast, DCs are the main source of IL-12 in early Leishmania infection. In fact, murine C57BL/6 skin-derived DCs were recognised as the main source of IL-12p40 immediately after dermot ...
CURRICULUM VITAE - University of Oxford
... in Professor McMichael’s laboratory, I was part of an exciting group and shared in the achievements of the team. This included the first application of the use of HLA tetrameric complexes to questions relevant to disease pathogenesis (HIV) and the identification of CD94 as being a ligand for HLA-E. ...
... in Professor McMichael’s laboratory, I was part of an exciting group and shared in the achievements of the team. This included the first application of the use of HLA tetrameric complexes to questions relevant to disease pathogenesis (HIV) and the identification of CD94 as being a ligand for HLA-E. ...
Tesi unita 08 - Padua@Research
... hampered by some of its characteristics, which make it difficult to be cultured in vitro. Little is know about how T. pallidum causes the syphilis, and in particular how T. pallidum survives within the host despite the immune response, thus giving a chronic disease, remains an unexplored issue. In t ...
... hampered by some of its characteristics, which make it difficult to be cultured in vitro. Little is know about how T. pallidum causes the syphilis, and in particular how T. pallidum survives within the host despite the immune response, thus giving a chronic disease, remains an unexplored issue. In t ...
LESSON 6 Your Immune System
... Lymphocytes react to antigens. The immune system responds to these antigens by producing antibodies. Lymphocytes known as B cells produce a specific antibody for each specific antigen. If the same type of pathogen invades the body again, these specific antibodies are ready to attack. New Vocabulary ...
... Lymphocytes react to antigens. The immune system responds to these antigens by producing antibodies. Lymphocytes known as B cells produce a specific antibody for each specific antigen. If the same type of pathogen invades the body again, these specific antibodies are ready to attack. New Vocabulary ...
Review Pattern Recognition Receptors and Inflammation Leading Edge
... differentiation of naive T cells into antigen-specific Th17 and Th1 cells (Uematsu et al., 2008). TLR11, which is present in mice but not in humans, shows close homology to TLR5. TLR11 recognizes uropathogenic bacteria and a profilin-like molecule derived from the intracellular protozoan Toxoplasma ...
... differentiation of naive T cells into antigen-specific Th17 and Th1 cells (Uematsu et al., 2008). TLR11, which is present in mice but not in humans, shows close homology to TLR5. TLR11 recognizes uropathogenic bacteria and a profilin-like molecule derived from the intracellular protozoan Toxoplasma ...
The Th1-Promoting Effects of Dehydroepiandrosterone
... (CAR), and estrogen receptor â have been elucidated and there is some evidence that DHEA and some of its metabolites either bind to or activate these newly characterized receptors.19 However, we must be aware that it is still a matter of debate whether immune cells (or any other cells) possess speci ...
... (CAR), and estrogen receptor â have been elucidated and there is some evidence that DHEA and some of its metabolites either bind to or activate these newly characterized receptors.19 However, we must be aware that it is still a matter of debate whether immune cells (or any other cells) possess speci ...
Chapter 15 The Lymphatic System and Immunity
... – B cell then divides and forms two clones of cells— plasma (effector) cells and memory cells – Plasma cells secrete antibodies into blood; memory cells are stored in lymph nodes – With re-exposure to antigen-memory cells become plasma cells and secrete antibodies ...
... – B cell then divides and forms two clones of cells— plasma (effector) cells and memory cells – Plasma cells secrete antibodies into blood; memory cells are stored in lymph nodes – With re-exposure to antigen-memory cells become plasma cells and secrete antibodies ...
A and B - Sorin Solomon
... surface of soil, and microbes that are very fastidious about oxygen concentration will be found in bands at the appropriate oxygen concentration." Microbes concentrating on a two-dimensional resource may have been more successful than their cousins who tried exploiting a three-dimensional feast.>> ...
... surface of soil, and microbes that are very fastidious about oxygen concentration will be found in bands at the appropriate oxygen concentration." Microbes concentrating on a two-dimensional resource may have been more successful than their cousins who tried exploiting a three-dimensional feast.>> ...
PDF - The Journal of Immunology
... poly(I:C)) are potent stimulators of type I IFNs. Particular unmethylated CpG dinucleotides, found preferentially in prokaryotic DNA, also exhibit a wide array of immunostimulatory properties (44). Finally, GPI protein anchors, abundantly expressed by some pathogenic protozoa, may bind the MHC class ...
... poly(I:C)) are potent stimulators of type I IFNs. Particular unmethylated CpG dinucleotides, found preferentially in prokaryotic DNA, also exhibit a wide array of immunostimulatory properties (44). Finally, GPI protein anchors, abundantly expressed by some pathogenic protozoa, may bind the MHC class ...
Animal Models for ALI
... Potent activator of the innate immune responses via TLR4 and little direct toxicity to cells in vitro ...
... Potent activator of the innate immune responses via TLR4 and little direct toxicity to cells in vitro ...
PARADOXICAL EFFECTS OF IMMUNE CELLS ON THE INFLAMMATION
... sulfonic acid (TNBS)-model of colitis in rats. Large increases in infiltrating granulocytes, particularly neutrophils and blood-derived monocytes were found in the muscularis layers adjacent to the ENS. A rapid increase in iNOS immunoreactivity in the muscularis regions during early stages of inflam ...
... sulfonic acid (TNBS)-model of colitis in rats. Large increases in infiltrating granulocytes, particularly neutrophils and blood-derived monocytes were found in the muscularis layers adjacent to the ENS. A rapid increase in iNOS immunoreactivity in the muscularis regions during early stages of inflam ...
Role of IL-12 in HIV infection and vaccine
... responses. In fact, IL-12 therapy is currently administered to patients with Kaposi’s sarcoma, for which other therapies have failed [29, 30]. It has to be borne in mind though that most opportunistic infections occur at late stages of HIV infection, following extensive erosion of immune competency ...
... responses. In fact, IL-12 therapy is currently administered to patients with Kaposi’s sarcoma, for which other therapies have failed [29, 30]. It has to be borne in mind though that most opportunistic infections occur at late stages of HIV infection, following extensive erosion of immune competency ...
Regulatory T Helper Cells in Pregnancy and Tolerance Linköping University Post Print
... development of organ-specific autoimmune diseases such as gastritis, oophoritis and thyroiditis. Notably, inflammatory disease was prevented by co-transfer of CD4+CD25+ cells. Subsequently it was shown that these cells migrate from thymus as a distinct cell subset32. In humans, the cell type corresp ...
... development of organ-specific autoimmune diseases such as gastritis, oophoritis and thyroiditis. Notably, inflammatory disease was prevented by co-transfer of CD4+CD25+ cells. Subsequently it was shown that these cells migrate from thymus as a distinct cell subset32. In humans, the cell type corresp ...
Chapter Twenty Four
... • Lymphatic ducts are formed from the fusion of lymphatic trunks. • The right lymphatic duct is located deep to the right clavicle and returns lymph at the junction of the right subclavian and internal jugular veins. • The right lymphatic duct returns lymph from the right side of the head and neck, ...
... • Lymphatic ducts are formed from the fusion of lymphatic trunks. • The right lymphatic duct is located deep to the right clavicle and returns lymph at the junction of the right subclavian and internal jugular veins. • The right lymphatic duct returns lymph from the right side of the head and neck, ...
Chapter 10: Circulatory System and Lymphatic
... are the primary lymphoid organs. Blood cells, including lymphocytes, are produced in red bone marrow. B cells mature in the bone marrow. T cells mature in the thymus. The lymph nodes (c) and the spleen (d) are secondary lymphoid organs. Lymph is cleansed in the nodes, and blood is cleansed in the sp ...
... are the primary lymphoid organs. Blood cells, including lymphocytes, are produced in red bone marrow. B cells mature in the bone marrow. T cells mature in the thymus. The lymph nodes (c) and the spleen (d) are secondary lymphoid organs. Lymph is cleansed in the nodes, and blood is cleansed in the sp ...
Chapter 10: Circulatory System and Lymphatic
... are the primary lymphoid organs. Blood cells, including lymphocytes, are produced in red bone marrow. B cells mature in the bone marrow. T cells mature in the thymus. The lymph nodes (c) and the spleen (d) are secondary lymphoid organs. Lymph is cleansed in the nodes, and blood is cleansed in the sp ...
... are the primary lymphoid organs. Blood cells, including lymphocytes, are produced in red bone marrow. B cells mature in the bone marrow. T cells mature in the thymus. The lymph nodes (c) and the spleen (d) are secondary lymphoid organs. Lymph is cleansed in the nodes, and blood is cleansed in the sp ...
Toward the understanding of autophagy regulation and its
... mechanism shared with other vesicle trafficking pathways. In this event, a key role is played by UVRAG, which, in addition to its function in the Beclin 1 complex, is also a component of the Class C Vps/HOPS proteins involved in the fusion mechanism. Three other papers in this review set describe in ...
... mechanism shared with other vesicle trafficking pathways. In this event, a key role is played by UVRAG, which, in addition to its function in the Beclin 1 complex, is also a component of the Class C Vps/HOPS proteins involved in the fusion mechanism. Three other papers in this review set describe in ...