Immunogenetics
... The Rhesus factor is an antigen on the surface of red blood cells. It was originally found in rhesus monkeys. About 85% of people have the Rh antigen (Rh+) and 15% lack it (Rh-). The Rh+ allele is dominant, so heterozygotes are Rh+. Because the + allele is dominant, it is possible for an Rhmother to ...
... The Rhesus factor is an antigen on the surface of red blood cells. It was originally found in rhesus monkeys. About 85% of people have the Rh antigen (Rh+) and 15% lack it (Rh-). The Rh+ allele is dominant, so heterozygotes are Rh+. Because the + allele is dominant, it is possible for an Rhmother to ...
Immunogenetics
... Class 1 MHC molecules are found on the surface of all nucleated cells. They are involved in cellular immunity. Class 2 MHC molecules are only found on the surface of cells that display antigens: macrophages and B cells. They are involved in humoral immunity. Structure: Both class 1 and class 2 molec ...
... Class 1 MHC molecules are found on the surface of all nucleated cells. They are involved in cellular immunity. Class 2 MHC molecules are only found on the surface of cells that display antigens: macrophages and B cells. They are involved in humoral immunity. Structure: Both class 1 and class 2 molec ...
Chapter_02_notes_large - Welcome to people.pharmacy.purdue
... RNA processing to generate BCR or Antibody ...
... RNA processing to generate BCR or Antibody ...
Membrane Receptors for Antigen
... • Expressed on nearly all cells of the animal, though are more abundant on some cells than others • In humans there are three main genes, located on Chromosome 6, called HLA-A, HLA-B and HLA-C (HLA stands for Human Leukocyte Antigen – they were originally called antigens because animals make antibod ...
... • Expressed on nearly all cells of the animal, though are more abundant on some cells than others • In humans there are three main genes, located on Chromosome 6, called HLA-A, HLA-B and HLA-C (HLA stands for Human Leukocyte Antigen – they were originally called antigens because animals make antibod ...
Streptococcal Serology powerpoint
... • Associated with large amount of M protein and a capsule • Due to immune response against Strep antigens similar to heart antigens. ...
... • Associated with large amount of M protein and a capsule • Due to immune response against Strep antigens similar to heart antigens. ...
Innate immune recognition
... Current concepts in innate immunity-II 5. Four groups of PRRs exist in host cells (immune & nonimmune cells), including: (1) TLRs, (2) RIG-like receptors (RLRs), (3) NOD-like receptors (NLRs), and (4) C-type lectin receptors (CLRs) 6. These PRRs distribute on cell surface, in cytosol, or in endosom ...
... Current concepts in innate immunity-II 5. Four groups of PRRs exist in host cells (immune & nonimmune cells), including: (1) TLRs, (2) RIG-like receptors (RLRs), (3) NOD-like receptors (NLRs), and (4) C-type lectin receptors (CLRs) 6. These PRRs distribute on cell surface, in cytosol, or in endosom ...
Lymphatic System
... - lymph that is drained from the body passes and is filtered through structures called lymph nodes. - connective tissue called reticular fibers and are populated by dense aggregates of lymphocytes and macrophages. -Lymph nodes occur along the entire length of the lymphatic system and tend to increas ...
... - lymph that is drained from the body passes and is filtered through structures called lymph nodes. - connective tissue called reticular fibers and are populated by dense aggregates of lymphocytes and macrophages. -Lymph nodes occur along the entire length of the lymphatic system and tend to increas ...
24. The Body`s Defenses
... Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings ...
... Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings ...
(RBC) coated with IgG anti-D bind transforming growth factor-beta
... fusion protein was compared using a number of vectors, including retroviral and adenoviral vectors. The resultant fusion protein, expressed by HeLa cells, was found by ELISA t o bind immobilised recombinant NCAM, and FACS analysis revealed binding to the human neuroblastoma cell line SKNBE and a mur ...
... fusion protein was compared using a number of vectors, including retroviral and adenoviral vectors. The resultant fusion protein, expressed by HeLa cells, was found by ELISA t o bind immobilised recombinant NCAM, and FACS analysis revealed binding to the human neuroblastoma cell line SKNBE and a mur ...
The Immune System
... Two constant heavy chains and two variable light chains. • The variable region binds to the epitope. • The constant region determines what type of antibody it is. ...
... Two constant heavy chains and two variable light chains. • The variable region binds to the epitope. • The constant region determines what type of antibody it is. ...
A Review of the Clonal Selection Theory of
... lymphocyte is a cell which can bind to antigen as well as producing antibodies. The physical surface of an antigen has a number of different structural features. An antibody and B cell have receptors which have a specificity (ability to bind) to only one surface feature of an antigen, although the f ...
... lymphocyte is a cell which can bind to antigen as well as producing antibodies. The physical surface of an antigen has a number of different structural features. An antibody and B cell have receptors which have a specificity (ability to bind) to only one surface feature of an antigen, although the f ...
The galectin family of mammalian carbohydrate
... with sites of tight adhesions in the developing epithelium, leading to the possibility that the lectin may serve to synergize with or activate other adhesive interactions. These interactions include cell-cell adhesions at lateral surfaces mediated by cadherin family members and cellmatrix adhesions ...
... with sites of tight adhesions in the developing epithelium, leading to the possibility that the lectin may serve to synergize with or activate other adhesive interactions. These interactions include cell-cell adhesions at lateral surfaces mediated by cadherin family members and cellmatrix adhesions ...
Clinical Management Plan for treatment of early breast cancer with
... daily as per BNF. 2 tablets 4 times daily as per BNF. 400mg 3 times daily as per BNF. ...
... daily as per BNF. 2 tablets 4 times daily as per BNF. 400mg 3 times daily as per BNF. ...
Immunology of Transplantation & Malignancy
... malignancies (particularly lympho-reticular tumors) in immunodeficient patients). ...
... malignancies (particularly lympho-reticular tumors) in immunodeficient patients). ...
T Cells
... How Antibodies Render Antigens Harmless 3) Agglutination An antibody may have up to 10 binding sites; thus, it can bind to antigens on more than one cell at a time. This immobilizes microbes and prevents them from spreading. ...
... How Antibodies Render Antigens Harmless 3) Agglutination An antibody may have up to 10 binding sites; thus, it can bind to antigens on more than one cell at a time. This immobilizes microbes and prevents them from spreading. ...
ABO Discrepancies & other problems
... When the results of the forward grouping (patient cells) is not matching the results of the reverse grouping (patient serum) or abnormal reactivity is present (i.e. Mixed Field) then we called this ABO discrepancy. The Discrepancy will be noticed by: Strength of reaction ...
... When the results of the forward grouping (patient cells) is not matching the results of the reverse grouping (patient serum) or abnormal reactivity is present (i.e. Mixed Field) then we called this ABO discrepancy. The Discrepancy will be noticed by: Strength of reaction ...
Janeway`s Immunology - Cal State LA
... • Hypersensitivity reactions are immune responses to innocuous, non-infectious, environmental antigen that lead to symptomatic reactions upon re-exposure • Harmful immune responses • Hypersensitivity diseases result from repetitively occurring reactions • Antigen is in this context “allergen” ...
... • Hypersensitivity reactions are immune responses to innocuous, non-infectious, environmental antigen that lead to symptomatic reactions upon re-exposure • Harmful immune responses • Hypersensitivity diseases result from repetitively occurring reactions • Antigen is in this context “allergen” ...
7 T cell
... •membrane-bound heterodimer composed of an α chain and a β chainm, each chain containing one variable (V) region and one constant (C) region Both the α chain and the β chain of the TCR participate in specific recognition of MHC molecules and bound peptides ...
... •membrane-bound heterodimer composed of an α chain and a β chainm, each chain containing one variable (V) region and one constant (C) region Both the α chain and the β chain of the TCR participate in specific recognition of MHC molecules and bound peptides ...
Hemolytic anemias
... increased, the body initially compensates by producing more RBCs; however, breakdown of RBCs can exceed the rate that the body can make RBCs, and so anemia can develop. ...
... increased, the body initially compensates by producing more RBCs; however, breakdown of RBCs can exceed the rate that the body can make RBCs, and so anemia can develop. ...
As HIV viral load increases CD4 cell count decreases and vise
... HIV-1 is found worldwide, HIV-2 is found primarily in West Africa Subtypes (clades): M group (subtypes A-K) and Subtype O (55-70% homology with M subtypes), N (“new”) subtype Diagnostic tests may preferentially detect a specific type or subtype Vaccines may need to be subtype specific ...
... HIV-1 is found worldwide, HIV-2 is found primarily in West Africa Subtypes (clades): M group (subtypes A-K) and Subtype O (55-70% homology with M subtypes), N (“new”) subtype Diagnostic tests may preferentially detect a specific type or subtype Vaccines may need to be subtype specific ...