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IP-1
IP-1

A Very Basic Approach to Transfusion Medicine
A Very Basic Approach to Transfusion Medicine

... • Carb. Epitopes on proteins and membrane lipids. • Posttranslational modifications under control of several enzyme known as glycosyltransferases. • Not red cell specific. – Therefore also play roles in organ tranplantation, cell development, cancer, and infectious disease. ...
Immunology. Mucosal and Body Surface Defences Brochure
Immunology. Mucosal and Body Surface Defences Brochure

... or across a mucosal tissue such as the respiratory tract or intestines, as these sites are the ones exposed to the external environment. By focusing on immunity at mucosal and body surfaces this book presents a fresh, new approach to the teaching of immunology. After an introduction to the basic str ...
Receptors
Receptors

... • small, not immunogenic molecules, commongy not of biological ethiology (synthetic epitopes) • are antigens able to bind on immunity receptors and not able to induce immunity reaction, not immunogenic • Hapten + immunogen (carrier) = immunity reaction against both ...
Document
Document

... Larger than T and B cells Activated during the innate response by macrophage derived cytokines Eg. IL-12 and Interferons Produce IFN- when activated Kills cells infected with intracellular pathogens Mechanism of Killing is similar to that of cytotoxic T cells ...
Multiple Sclerosis
Multiple Sclerosis

... A. Activation of B-cells and T-cells by the Epstein Barr Virus B. Release of chemokines that propagate inflammatory response C. Breakdown of the separation between CSF and systemic circulation D. Degradation of oligodendrocytes 3. All of the following demonstrate the role of vitamin D in MS, EXCEPT ...
T cell activation
T cell activation

... Type of Memory cells 1. Central memory T cells express the CCR7 and L-Selectin and home mainly to lymph nodes. They have a limited effector function, but In response to Ag challenge rapidly proliferate and generate many effector cells. 2. Effector memory T cells do not express CCR7 or L-selectin an ...
Viral Infection and immunity
Viral Infection and immunity

... • Phagocytic Barriers : 3 major types of phagocytic cells • Inflammatory Barriers and fever • Mucociliary clearance ...
LESSON 3.3 WORKBOOK How can the immune system
LESSON 3.3 WORKBOOK How can the immune system

... regulators of the cell cycle, because it controls the R transition point. Recall that Rb serves as a gatekeeper to control the cell cycle because once cells have passed the R point they are committed to the cell cycle and no longer need extracellular growth signals.. The main goal of DNA tumor virus ...
УДК 616
УДК 616

Antibodies - STEMCELL Technologies
Antibodies - STEMCELL Technologies

... The RMEPCR1560 antibody reacts with the endothelial protein C receptor (EPCR or CD201), an ~25 kDa type I transmembrane glycoprotein expressed by endothelial cells, subsets of hematopoietic stem cells (HSCs) and dendritic cells, and several malignant cell lines. It is also found in a soluble form in ...
Guillain-Barre Syndrome
Guillain-Barre Syndrome

... • CD8- recognize epitopes paired c MHC-I • CD4- activate and control the immune response • Scavenger cells break down antigen into small peptide fragments (T cell epitopes), MHC-II epitope complexes are expressed on the surface & the scavenger become an APC which docks on a CD4 c a compatible TCR. C ...
- Free Documents
- Free Documents

... Also known as tissuespecific, cytotoxic, or cytolytic hypersensitivity Antibodies attack normal antigens on surface of specific cells or tissues Often immediate reaction, but some occur over time mins Cell lysis may be mediated by Activated complement fragments membrane attack complex Phagocytic cel ...
Accessary cells: in adaptive immunity are cells aid in the response
Accessary cells: in adaptive immunity are cells aid in the response

... Allergens: antigens elicit hypersensitivity or allergic reaction Allergic asthma: constriction of the bronchial tree due to an allergic reaction to inhaled antigen Allergic reaction: a response to innocuous environment antigens or allergens due to pre-existing antibody or T cells (mostly the binding ...
Spring Time Allergies
Spring Time Allergies

... coordinated and controlled by the nervous system. For example, nerve cell endings in the skin and white blood cells of the immune system are in intimate contact, and chemicals secreted by the nerves can shut down immune system cells nearby. The most common immune disorder is the allergic reaction wh ...
PowerPoint Presentation - Atypical Cutaneous Leishmaniasis
PowerPoint Presentation - Atypical Cutaneous Leishmaniasis

...  These anti-microbial enzymes and reactive molecules ...
AUTOIMMUNE DISEASES Systemic VS Organ
AUTOIMMUNE DISEASES Systemic VS Organ

... Read on to learn about the natural course, causes, symptoms, subtypes and treatment of autoimmune diseases. What are Autoimmune Diseases? Autoimmune disease is a term that encompasses more than one hundred distinct disorders that originate in the immune system. The immune system is a network of orga ...
Blood
Blood

Blood
Blood

... functions to protect the body from foreign antigens (substances that trigger an immune response) – pathogen • disease producing biological agent – allergen • substance that causes an allergic reaction • Exit blood vessels functioning extravascularly where they live within tissues for a few hours to ...
Patient Consent Form (Warts)
Patient Consent Form (Warts)

... multiple treatments may be required and it is possible the result will be minimal or may not help at all. The procedure may result in the following adverse experiences or risks:  DISCOMFORT/PAIN –Discomfort and pain may be experienced during treatment.  REDNESS/SWELLING/BRUISING – Short term redne ...
PSYCHONEUROIMMUNOLOGY
PSYCHONEUROIMMUNOLOGY

... Work of IS is carried out by T-cells and Bcells T-cells (thymus) eliminate antigens by attacking them directly or by initiating a cascade of events that results in the release of lymphokines—”natural drug” of IS: structurally a peptide product of T-cells ...
mucosal immunity
mucosal immunity

... HUMORAL IMMUNITY: MASSIVE INCREASE IN THE NUMBER OF PLASMA CELLS AND IN IgG PRODUCTION (IgG2 IN CD AND IgG1 IN UC) IMBALANCE OF PRO-INFLAMMATORY (TNF-a, ...
Findings Presented at 49th ICAAC Conference -- For
Findings Presented at 49th ICAAC Conference -- For

... About AVI BioPharma AVI BioPharma is focused on the discovery and development of RNA-based drugs utilizing proprietary derivatives of its antisense chemistry, (morpholino phosphorodiamidate oligomers or PMOs) that can be applied to a wide range of diseases and genetic disorders through several disti ...
Immune Responses to Infectious Diseases
Immune Responses to Infectious Diseases

... However the phagocytic activity is strictly dependent on the size of the pathogens [15]. This is well demonstrated with respect to the host defense against helminths, in which phagocytosis by macrophages or neutrophils are prevented by the parasite size. This restriction demands a different strategy ...
TA - PLOS
TA - PLOS

... concerning the prevention of AIDS associated cryptococcosis in patients with CD4+ count ≤ 100 cells/µl and without clinical signs of meningoencephalitis: (1) a no intervention strategy, which simulates the natural history of AIDS patients; (2) a systematic prophylaxis strategy, which simulates the n ...
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Immunosuppressive drug

For a list of immunosuppressive drugs, see the transplant rejection page.Immunosuppressive drugs or immunosuppressive agents or antirejection medications are drugs that inhibit or prevent activity of the immune system. They are used in immunosuppressive therapy to: Prevent the rejection of transplanted organs and tissues (e.g., bone marrow, heart, kidney, liver) Treat autoimmune diseases or diseases that are most likely of autoimmune origin (e.g., rheumatoid arthritis, multiple sclerosis, myasthenia gravis, systemic lupus erythematosus, sarcoidosis, focal segmental glomerulosclerosis, Crohn's disease, Behcet's Disease, pemphigus, and ulcerative colitis). Treat some other non-autoimmune inflammatory diseases (e.g., long term allergic asthma control).A common side-effect of many immunosuppressive drugs is immunodeficiency, because the majority of them act non-selectively, resulting in increased susceptibility to infections and decreased cancer immunosurveillance. There are also other side-effects, such as hypertension, dyslipidemia, hyperglycemia, peptic ulcers, lipodystrophy, moon face, liver and kidney injury. The immunosuppressive drugs also interact with other medicines and affect their metabolism and action. Actual or suspected immunosuppressive agents can be evaluated in terms of their effects on lymphocyte subpopulations in tissues using immunohistochemistry.Immunosuppressive drugs can be classified into five groups: glucocorticoids cytostatics antibodies drugs acting on immunophilins other drugs.
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