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The Janus face of immunity : how anti-tumor
The Janus face of immunity : how anti-tumor

... To cite this version: Christina Gebauer. The Janus face of immunity : how anti-tumor immunity leads to autoimmunity in paraneoplastic neurological diseases. Immunology. Université Paul Sabatier - Toulouse III, 2016. English. . ...
Immune components of bovine colostrum and milk
Immune components of bovine colostrum and milk

... only kill bacteria directly through phagocytosis, but are also responsible for the production of many cytokines, reactive oxygen species, and antimicrobial peptides. Several recent reports surveying the minor constituents of milk from healthy and infected glands have noted the predominance of host d ...
Mucosal candidiasis elicits NF-κB activation, proinflammatory gene
Mucosal candidiasis elicits NF-κB activation, proinflammatory gene

... Mucosal candidiasis is the most common form of infection by C. albicans (Moran et al., 2012), but available in vivo animal models have limitations for imaging immune cell and pathogen interactions intravitally. We sought to exploit the transparency of the juvenile zebrafish to investigate the intera ...
Surgical Neurology International
Surgical Neurology International

... Over the past several decades we have learned a great deal about microglia and innate brain immunity. While microglia are the principle innate immune cells, other cell types also play a role, including invading macrophages, astrocytes, neurons, and endothelial cells. The fastest reacting cell is the ...
Monocytes Are Major Players in the Prognosis and
Monocytes Are Major Players in the Prognosis and

... immunity as antigen-presenting cells, and they are the main effectors of innate immunity through the expression of pattern recognition receptors.10,11 These receptors include the Toll-like receptors (TLR), which are linked to intracellular signal transduction pathways that regulate the inflammatory ...
the innate immunity in bovine mastitis
the innate immunity in bovine mastitis

... sites in their promoter region and transcription factor complex act as a main switch to orchestrate immune defense genes against bacterial infection, as production of several pro-inflammatory cytokines. Thus, the innate immune system uses various PRRs that are expressed on the cell surface, in intra ...
Microbiota-mediated colonization resistance against intestinal
Microbiota-mediated colonization resistance against intestinal

... Box 2 | Microbiota-derived molecules enhance mucosal immunity ...
Bacterial lipopolysaccharide stimulates bovine neutrophil production
Bacterial lipopolysaccharide stimulates bovine neutrophil production

... by inducing vascular endothelial adhesion molecule expression. These two cytokines also increase hepatic synthesis of acute phase proteins that facilitate complement activation and host detection of bacterial cell wall products [15, 18]. PMN recruitment to the site of infection is further mediated b ...
to View the Official Conference Program Book
to View the Official Conference Program Book

... The purpose of this conference is to review fundamentals of innate immunity and how various cardiovascular diseases affect these functions. Particular areas of interest include monocyte/macrophages, complement and reactive oxygen species. As well as review fundamentals of adaptive immunity, and in p ...
Medical Veterinary Entomology
Medical Veterinary Entomology

... molecules excreted/secreted by larvae, of which salivary antigens are those mainly recognized by the host’s immune system. The recruitment of immune reactive cells increases gradually from the nasal to sinus cavities in infected hosts. Mast cells, eosinophils, macrophages and lymphocytes are always ...
cord day
cord day

... Figure 4. Causes of death in 109 patients randomized to receive no ATG (n 5 53), 7.5 mg/kg ATG (n 5 29), or 15 mg/kg ATG (n 5 27). Acute GVHD was the cause of death in 36% of patients not receiving ATG, 28% of patients receiving 7.5 mg/kg ATG, and 11% of patients receiving 15 mg/kg ATG. Infections w ...
ICH E10
ICH E10

... studies are predictive of human immunotoxicity in a rather straightforward manner. That is, specific assays to determine immunotoxicity are probably not valuable in drug risk assessment since the target tissues are usually rapidly dividing cell types, such as bone marrow-derived immune system progen ...
Probiotics for the Immune System
Probiotics for the Immune System

... suppressing the inflammation process caused by pathogens. Probiotics also stimulate immune cells to better tell the difference between harmful and beneficial bacteria.5 • Stimulate IgA production. The positive influence of probiotics on IgA in the intestinal mucosal lining may improve immune functio ...
against Oviduct Disease to Induce Immune Pathology and Protect
against Oviduct Disease to Induce Immune Pathology and Protect

... to induce oviduct pathology. A, Intensity and duration of lower genital tract infection are not affected by loss of the chlamydial plasmid. Quantitative IFU from cervical swabs obtained after infection with Nigg (Œ), CM972 (E), or CM3.1 (f). Data points are means ⫾ SD with 15 animals examined each d ...
b - Repositório da Universidade de Lisboa
b - Repositório da Universidade de Lisboa

... away, by skype, whatsapp or facebook you all have been there for me. A special thanks: to my Grandma that always makes me miss home and her food; to my worried Grandpa that sends me emails with passages from his diary making me go back to my childhood; to my mother for all the weekend chats; to my a ...
ASH 2008 Advances in ITP Research both Basic and Clinical
ASH 2008 Advances in ITP Research both Basic and Clinical

... • The Pathophysiology of ITP Revisited: Ineffective Thrombopoiesis and the Emerging Role of Thrombopoietin Receptor Agonists in the Management of Chronic Immune Thrombocytopenic ...
EIR 14
EIR 14

... receptor complex, which provides this characteristics. subset an advantage of responding to very low concentrations of IL-2 (7). IL-2-induced activation of CD56bright cells results in the production of relatively large amounts of IFN-γ, which can shape the Th1 immune response (28). Once activated, C ...
Treatment for LTBI in contacts of MDR-TB patients - CAP-TB
Treatment for LTBI in contacts of MDR-TB patients - CAP-TB

... Nine of the 61 adult contacts reported a history of DM, and the remaining 52 adult contacts had random blood glucose levels that were not indicative of DM (,200 mg/dl) at baseline screening. None of the children had DM according to medical history. DOT workers compiled missed doses and adverse effec ...
La Terraza Del Casino Madrid Tripadvisor - Info!
La Terraza Del Casino Madrid Tripadvisor - Info!

... size of a fist. They drain into two tubes called the ureters, which lead into the bladder. The kidney is a very important organ, and the most obvious function is that it excretes wastes that we produce from our diet and from our metabolism. What's less obvious is that it's the most important organ t ...
The regulation of IL‑10 production by immune cells
The regulation of IL‑10 production by immune cells

Analysis of Vγ9Vδ2 T lymphocytes response to human glioma cell
Analysis of Vγ9Vδ2 T lymphocytes response to human glioma cell

... the first line of defense against infections and tumors by using a fast nonspecific response, that followed by the induction of specific, acquired immune response able to trigger very effective protection mechanisms such as cell-mediated immunity and humoral immunity and inducing immunological memor ...
Brock_Allison_David_2011
Brock_Allison_David_2011

... motor and sensory losses as the largest area of concern. Loss of function below the level of the lesion produces numerous obstacles making the performance of activities of daily living and the maintenance of an independent lifestyle an arduous task. Unfortunately, the immediate functional consequenc ...
Divergent TLR7 and TLR9 signaling and type I interferon production
Divergent TLR7 and TLR9 signaling and type I interferon production

... Pathogenic HIV infections of humans and simian immunodeficiency virus (SIV) infections of rhesus macaques are characterized by generalized immune activation and progressive CD4+ T cell depletion. In contrast, natural reservoir hosts for SIV, such as sooty mangabeys, do not progress to AIDS and show ...
Dear (name of editor):
Dear (name of editor):

... decrease in platelet count to less than 150 x109/L.1 It can result in increased length of hospital stay and risk of death. Drug-induced thrombocytopenia (DITP) can result from a decrease in platelet production through a direct toxic effect on the thrombopoietic mechanisms in the bone marrow or an in ...
References
References

... Horiuchi, S., Takahashi, K., Kruijt, J.K., van Berkel, T.J.C., Steinbreger, U.P., Ishibashi, S., Maeda, N., Gordon, S., Kodama, T., A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection. Nature, 1997. 386: p. 292-296. Majumdar, S., Basu, S.K., Killing of intrac ...
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Immunosuppressive drug

For a list of immunosuppressive drugs, see the transplant rejection page.Immunosuppressive drugs or immunosuppressive agents or antirejection medications are drugs that inhibit or prevent activity of the immune system. They are used in immunosuppressive therapy to: Prevent the rejection of transplanted organs and tissues (e.g., bone marrow, heart, kidney, liver) Treat autoimmune diseases or diseases that are most likely of autoimmune origin (e.g., rheumatoid arthritis, multiple sclerosis, myasthenia gravis, systemic lupus erythematosus, sarcoidosis, focal segmental glomerulosclerosis, Crohn's disease, Behcet's Disease, pemphigus, and ulcerative colitis). Treat some other non-autoimmune inflammatory diseases (e.g., long term allergic asthma control).A common side-effect of many immunosuppressive drugs is immunodeficiency, because the majority of them act non-selectively, resulting in increased susceptibility to infections and decreased cancer immunosurveillance. There are also other side-effects, such as hypertension, dyslipidemia, hyperglycemia, peptic ulcers, lipodystrophy, moon face, liver and kidney injury. The immunosuppressive drugs also interact with other medicines and affect their metabolism and action. Actual or suspected immunosuppressive agents can be evaluated in terms of their effects on lymphocyte subpopulations in tissues using immunohistochemistry.Immunosuppressive drugs can be classified into five groups: glucocorticoids cytostatics antibodies drugs acting on immunophilins other drugs.
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