• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
The Immune System The immune system consists of all the tissues
The Immune System The immune system consists of all the tissues

Adaptive (Specific) Immunity Mo O`Brien Lecturer
Adaptive (Specific) Immunity Mo O`Brien Lecturer

... antigens present on the macrophage that the T cell can recognise as belonging to ‘self’. ‘Self’ antigens are know as MHC (major histocompatibility complex) antigens because of their importance in cross matching for tissue transplantation ...
Slackers Bacteriology Fact Stack  - U
Slackers Bacteriology Fact Stack - U

... buccal mucosa coupled with a yellow white exudate on the tongue punctuated by red papillae (strawberry tongue). A diffuse red “sandpaper” rash appears on the second day of illness and spreads to the trunk ...
Identification of CD8+ Cytotoxic T Lymphocytes (CTL) Specific for
Identification of CD8+ Cytotoxic T Lymphocytes (CTL) Specific for

A Variant of the Endothelial Nitric Oxide Synthase Gene is a Risk
A Variant of the Endothelial Nitric Oxide Synthase Gene is a Risk

... chronic shortage of allogeneic organs and currently the pig is thought to be the most suitable donor for man. However, porcine organs are rejected rapidly by a vascular process called hyperacute rejection (HAR) which has so far prevented clinical xenotransplantation. It is likely that this barrier w ...
FMB I PG - E
FMB I PG - E

... 5. A unicellular heterotroph with a nucleus but possess 70S ribosomes and lack golgi apparatuses should be placed in which kingdom a. Fungi b. Eubacteria c.Archezoa d. Chromista e. Animalia 6. Biochemical tests are used to determine _____________ a. enzymatic activities b. nucleic acid base composit ...
Immunity
Immunity

... * Memory cells * Life span of years to decades * Differentiate into plasma cells following stimulation by same antigen ...
Chapter 43 Presentation
Chapter 43 Presentation

...  Class II MHC molecules are made by only a few types of cells-dendritic cells, macrophages, and B-cells.  These bind peptides derived from foreign materials that have been fragmented and internalized. ...
Activated PI3K Syndrome: PIK3R1 Disease Fact Sheet
Activated PI3K Syndrome: PIK3R1 Disease Fact Sheet

... PIK3R1 disease is a rare genetic disease of the immune system that was first described in 2013. The disease goes by several names, including activated PI3K syndrome. It is sometimes called PASLI, which stands for PI3K-activating mutation causing senescent T cells, lymphadenopathy, and immunodeficien ...
Immunomodulation and Cancer
Immunomodulation and Cancer

... – Genetic hallmark is chromosomal translocations resulting from aberrant rearrangements of IG and B(or T) cell receptor genes – Leads to inappropriate expression of genes at reciprocal breakpoints that regulate a variety of cellular functions • gene transcription, cell cycle, apoptosis, and tumor pr ...
Differences Between Acute and Chronic Inflammation
Differences Between Acute and Chronic Inflammation

Complement Power Point
Complement Power Point

... X Complement A group of serum proteins that activates each other in an orderly fashion to generate biologically active molecules. ...
chapter15
chapter15

... Molecules of the innate phase are everpresent, thus act immediately upon a danger signal ...
Table of contents
Table of contents

... Characterization of the CD30 antigen has shown it to be in its mature form a transmembrane protein of about 120kDa (12, 22) elaborated from an 84kD cytoplasmic precursor primarily through glycosylation . The cloning of the CD30 gene has allowed the identification of a cDNA with an open reading frame ...
You are a Body Cell!
You are a Body Cell!

... 4. Macrophages eat the pathogens tagged with Antibodies (when not inside a cell). 5. Killer T cells destroy any cells that have become infected with pathogenic virus. Allow students to switch roles and attempt to walk each other through the scenario again. Now it’s your turn … Closure: This simulati ...
Thyroid Autoimmune Diseases:
Thyroid Autoimmune Diseases:

... Differential diagnosis of Chronic thyroiditis: -The hallmark of the diagnosis of this disease is the presence of circulating Autoantibodies: 1-Anti-thyroglobulin antibodies. 2-Anti-thyroid peroxidase antibodies. -These antibodies show a sensitivity of 90% and detected by: ...
IMMUNISATION: HOW DOES IT WORK? File
IMMUNISATION: HOW DOES IT WORK? File

... Antigens • Distinguishes between self (own body) and non-self (foreign substanes) • Any foreign substances recognised by the immune system are called antigens .(A molecule that is recognised by the immune system ) ...
immune system - SCIS Teachers
immune system - SCIS Teachers

... opportunistic infectious (pneumonia, meningitis, cancers that would normally be resisted by a person with a healthy immune system. ...
Lymphatic system - Seattle Central
Lymphatic system - Seattle Central

... • pre-T cells originate in red marrow • Migrate to, and mature in, thymus (into T-cells) ...
immunity - WordPress.com
immunity - WordPress.com

... Kill tumor cells & virus infected cells - non specific just destroy any cell that can develop tumor -they are called natural killer cells because the cells kill without the need of antigen –specific activation but enhanced by exposure to certain cytokines ( interferons) produced by virus infected ce ...
Mucosal Immunity Part 2
Mucosal Immunity Part 2

... mucosa to prevent reaction to harmless Ags such as commensals or foods – the generation of systemic immune unresponsiveness by feeding of antigen ...
understanding the Immune System and AIDS Vaccine Strategies
understanding the Immune System and AIDS Vaccine Strategies

... invading virus, acting within hours. These responses are not specific, so whether the pathogen is a cold virus or HIV, the response will be very similar. Innate immune responses don’t always clear an infection. Instead they help control the virus until the adaptive immune responses are ready to kick ...
Mapping of Scientific Workflow within the e
Mapping of Scientific Workflow within the e

... • Basic of how biology gets things done: -Give structure to our hair, skin, bones -Act as hormones and enzymes -Act as antibodies in support of the immune system. e.g.Gastrin -> Stomach->causes HCL production • For this reason, scientists have sequenced the human genome - DNA code which specifies th ...
Viral immunology: reunion of the conjoined twins disciplines
Viral immunology: reunion of the conjoined twins disciplines

chapter outline - McGraw Hill Higher Education
chapter outline - McGraw Hill Higher Education

... migrate to tissues where they mature into macrophages b. Macrophages—larger than monocytes; have more organelles and possess receptors that allow them to discriminate self from nonself; surface molecules recognize common components of pathogens (pathogen-associated molecular patterns) and enable pat ...
< 1 ... 347 348 349 350 351 352 353 354 355 ... 514 >

Molecular mimicry

Molecular mimicry is defined as the theoretical possibility that sequence similarities between foreign and self-peptides are sufficient to result in the cross-activation of autoreactive T or B cells by pathogen-derived peptides. Despite the promiscuity of several peptide sequences which can be both foreign and self in nature, a single antibody or TCR (T cell receptor) can be activated by even a few crucial residues which stresses the importance of structural homology in the theory of molecular mimicry. Upon the activation of B or T cells, it is believed that these ""peptide mimic"" specific T or B cells can cross-react with self-epitopes, thus leading to tissue pathology (autoimmunity). Molecular mimicry is a phenomenon that has been just recently discovered as one of several ways in which autoimmunity can be evoked. A molecular mimicking event is, however, more than an epiphenomenon despite its low statistical probability of occurring and these events have serious implications in the onset of many human autoimmune disorders. In the past decade the study of autoimmunity, the failure to recognize self antigens as ""self,"" has grown immensely. Autoimmunity is a result of a loss of immunological tolerance, the ability for an individual to discriminate between self and non-self. Growth in the field of autoimmunity has resulted in more and more frequent diagnosis of autoimmune diseases. Consequently, recent data show that autoimmune diseases affect approximately 1 in 31 people within the general population. Growth has also led to a greater characterization of what autoimmunity is and how it can be studied and treated. With an increased amount of research, there has been tremendous growth in the study of the several different ways in which autoimmunity can occur, one of which is molecular mimicry. The mechanism by which pathogens have evolved, or obtained by chance, similar amino acid sequences or the homologous three-dimensional crystal structure of immunodominant epitopes remains a mystery.
  • studyres.com © 2026
  • DMCA
  • Privacy
  • Terms
  • Report