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Feline Leukemia Virus (FeLV)- Specific IFNγ+ T
Feline Leukemia Virus (FeLV)- Specific IFNγ+ T

... cats, the majority will die from degenerative diseases while a minority will develop neoplastic and proliferative diseases.4 In general, viremic cats succumb to FeLV-related diseases within 2-4 years of infection. An improved understanding of the contribution of the different immune responses to the ...
Immunology - WordPress.com
Immunology - WordPress.com

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... 77) What is an example of vector transmission? 78) What is an organism that causes disease? 79) The type of pathogen that only causes disease when they have an opportunity? 80) What are some STD viruses? 81) What is the virus that infects white blood cells? 82) What are some diseases that are the ex ...
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... Abstract The possible existence of a peculiar form of adaptive immunity in invertebrates is important for a better understanding of immunological evolution and for the development of vaccination strategies. These may be relevant in the control of infectious diseases, common under intensive farming o ...
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Immune Cells
Immune Cells

... c. They signal the start of the immune response. CD8 receptors do all of those things, but they don’t kick off the immune response (the helper T cell does that). CD8 receptors are found on cytotoxic T cells; as the name implies, they kill the infected cell. ...
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Molecular mimicry

Molecular mimicry is defined as the theoretical possibility that sequence similarities between foreign and self-peptides are sufficient to result in the cross-activation of autoreactive T or B cells by pathogen-derived peptides. Despite the promiscuity of several peptide sequences which can be both foreign and self in nature, a single antibody or TCR (T cell receptor) can be activated by even a few crucial residues which stresses the importance of structural homology in the theory of molecular mimicry. Upon the activation of B or T cells, it is believed that these ""peptide mimic"" specific T or B cells can cross-react with self-epitopes, thus leading to tissue pathology (autoimmunity). Molecular mimicry is a phenomenon that has been just recently discovered as one of several ways in which autoimmunity can be evoked. A molecular mimicking event is, however, more than an epiphenomenon despite its low statistical probability of occurring and these events have serious implications in the onset of many human autoimmune disorders. In the past decade the study of autoimmunity, the failure to recognize self antigens as ""self,"" has grown immensely. Autoimmunity is a result of a loss of immunological tolerance, the ability for an individual to discriminate between self and non-self. Growth in the field of autoimmunity has resulted in more and more frequent diagnosis of autoimmune diseases. Consequently, recent data show that autoimmune diseases affect approximately 1 in 31 people within the general population. Growth has also led to a greater characterization of what autoimmunity is and how it can be studied and treated. With an increased amount of research, there has been tremendous growth in the study of the several different ways in which autoimmunity can occur, one of which is molecular mimicry. The mechanism by which pathogens have evolved, or obtained by chance, similar amino acid sequences or the homologous three-dimensional crystal structure of immunodominant epitopes remains a mystery.
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