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ASAM: Safe Methadone Induction and Stabilization
... Action Group recognize that not all treatment providers will be able to conform to each of the strategies recommended here. Instead, physicians and other staff are encouraged to consider these conclusions and strategies to the extent they and their patients are able to do so. Nothing in this documen ...
... Action Group recognize that not all treatment providers will be able to conform to each of the strategies recommended here. Instead, physicians and other staff are encouraged to consider these conclusions and strategies to the extent they and their patients are able to do so. Nothing in this documen ...
as a PDF
... transplant rejection or diffuse alveolar haemorrhage due to autoimmune diseases. In these patients, high doses of glucocorticoids are usually administered intravenously. The second category includes chronic diseases such as rheumatoid arthritis or the nephrotic syndrome. In these patients, low-dose ...
... transplant rejection or diffuse alveolar haemorrhage due to autoimmune diseases. In these patients, high doses of glucocorticoids are usually administered intravenously. The second category includes chronic diseases such as rheumatoid arthritis or the nephrotic syndrome. In these patients, low-dose ...
product monograph
... Sensitivity to topically applied aminoglycosides may occur in some patients. The severity of hypersensitivity reactions may vary from local effects to generalized reactions, such as erythema, itching, urticaria, skin rash, anaphylaxis, anaphylactoid reactions, or bullous reactions. If a hypersensiti ...
... Sensitivity to topically applied aminoglycosides may occur in some patients. The severity of hypersensitivity reactions may vary from local effects to generalized reactions, such as erythema, itching, urticaria, skin rash, anaphylaxis, anaphylactoid reactions, or bullous reactions. If a hypersensiti ...
DEXDOMITOR 0.5 mg/mL
... Apnea may occur with dexmedetomidine use. In the event of apnea, additional oxygen should be supplied. Administration of ANTISEDAN (atipamezole) to dogs is warranted when apnea is accompanied by bradycardia and cyanotic mucous membranes. Adverse reaction reports for dexmedetomidine in cats include r ...
... Apnea may occur with dexmedetomidine use. In the event of apnea, additional oxygen should be supplied. Administration of ANTISEDAN (atipamezole) to dogs is warranted when apnea is accompanied by bradycardia and cyanotic mucous membranes. Adverse reaction reports for dexmedetomidine in cats include r ...
Discriminative Stimulus Effects of Zolpidem in Pentobarbital
... 80% drug-appropriate responding) in all rats tested (Depoortere et al., 1986; Sanger et al., 1987). Conversely, when zolpidem (2.0 mg/kg) was trained as a discriminative stimulus, triazolam and chlordiazepoxide occasioned only partial drugappropriate responding, even at doses that significantly supp ...
... 80% drug-appropriate responding) in all rats tested (Depoortere et al., 1986; Sanger et al., 1987). Conversely, when zolpidem (2.0 mg/kg) was trained as a discriminative stimulus, triazolam and chlordiazepoxide occasioned only partial drugappropriate responding, even at doses that significantly supp ...
Presentation
... Chloroquine and Hydroxychloroquine - effects of Neostigmine may be diminished because of potential for Chloroquine and Hydroxychloroquine to increase symptoms of myasthenia gravis Many drugs have antimuscarinic effects; concomitant use of two or more such drugs can increase side-effects such as dry ...
... Chloroquine and Hydroxychloroquine - effects of Neostigmine may be diminished because of potential for Chloroquine and Hydroxychloroquine to increase symptoms of myasthenia gravis Many drugs have antimuscarinic effects; concomitant use of two or more such drugs can increase side-effects such as dry ...
Keppra, INN-Levetiracetam
... Levetiracetam is a white to off-white crystalline powder. It has one chiral center and is the Senantiomer of the pair of stereoisomers. Levetiracetam is synthesised by a route in seven stages. The synthesis and the in-process controls are satisfactorily described. The solubility, at room temperature ...
... Levetiracetam is a white to off-white crystalline powder. It has one chiral center and is the Senantiomer of the pair of stereoisomers. Levetiracetam is synthesised by a route in seven stages. The synthesis and the in-process controls are satisfactorily described. The solubility, at room temperature ...
Core Data Sheet
... Reduced liver function affects the elimination of corticosteroids, causing lower elimination rate and higher systemic exposure. Be aware of possible systemic side effects. Special caution is necessary in patients with active or quiescent pulmonary tuberculosis, and in patients with fungal or viral i ...
... Reduced liver function affects the elimination of corticosteroids, causing lower elimination rate and higher systemic exposure. Be aware of possible systemic side effects. Special caution is necessary in patients with active or quiescent pulmonary tuberculosis, and in patients with fungal or viral i ...
Renerve P - SR
... Dizziness, somnolence, loss of consciousness, confusion, and mental impairment Pregabalin treatment has been associated with dizziness and somnolence, which could increase the occurrence of accidental injury (fall) in the elderly population. There have also been postmarketing reports of loss of cons ...
... Dizziness, somnolence, loss of consciousness, confusion, and mental impairment Pregabalin treatment has been associated with dizziness and somnolence, which could increase the occurrence of accidental injury (fall) in the elderly population. There have also been postmarketing reports of loss of cons ...
Ceftin (cefuroxime axetil) tablets USP - GlaxoSmithKline
... Clostridium difficile-associated disease (CDAD) has been reported with use of many antibacterial agents including CEFTIN® (see ADVERSE REACTIONS). CDAD may range in severity from mild diarrhea to fatal colitis. It is important to consider this diagnosis in patients who present with diarrhea, or symp ...
... Clostridium difficile-associated disease (CDAD) has been reported with use of many antibacterial agents including CEFTIN® (see ADVERSE REACTIONS). CDAD may range in severity from mild diarrhea to fatal colitis. It is important to consider this diagnosis in patients who present with diarrhea, or symp ...
methotrexate - Cancer Care Ontario
... albumin or persistent liver abnormalities may indicate serious liver toxicity. This occurs more frequently in patients receiving moderate to high methotrexate doses. Chronic hepatic fibrosis is more common in patients receiving long-term, low-dose therapy and may be fatal. Clearance of methotrexat ...
... albumin or persistent liver abnormalities may indicate serious liver toxicity. This occurs more frequently in patients receiving moderate to high methotrexate doses. Chronic hepatic fibrosis is more common in patients receiving long-term, low-dose therapy and may be fatal. Clearance of methotrexat ...
Shining a Light on MEDs
... analgesics for the treatment of pain caused by a workplace injury.1 But with the use of opioids also comes inherent risks, such as addiction, tolerance, dependence, misuse, abuse and even death. According to a recent study by the Centers for Disease Control and Prevention, 46 people die every day fr ...
... analgesics for the treatment of pain caused by a workplace injury.1 But with the use of opioids also comes inherent risks, such as addiction, tolerance, dependence, misuse, abuse and even death. According to a recent study by the Centers for Disease Control and Prevention, 46 people die every day fr ...
Pyrethroid Insecticides: Use, Environmental Fate, and
... Fishel, 2005). Chronic animal feeding studies have produced high no-effect levels, indicating both a low potential to bioaccumulate and proficient detoxicification in mammalian receptors. In addition, although these compounds are categorized as highly toxic to very highly toxic to nontarget fish and ...
... Fishel, 2005). Chronic animal feeding studies have produced high no-effect levels, indicating both a low potential to bioaccumulate and proficient detoxicification in mammalian receptors. In addition, although these compounds are categorized as highly toxic to very highly toxic to nontarget fish and ...
prescribing information xylocaine viscous 2%
... PATIENTS SHOULD BE INSTRUCTED TO STRICTLY ADHERE TO THE RECOMMENDED DOSAGE. This is especially important in children where doses vary with weight. The management of serious adverse reactions may require the use of resuscitative equipment, oxygen and, other resuscitative drugs (see OVERDOSAGE). ...
... PATIENTS SHOULD BE INSTRUCTED TO STRICTLY ADHERE TO THE RECOMMENDED DOSAGE. This is especially important in children where doses vary with weight. The management of serious adverse reactions may require the use of resuscitative equipment, oxygen and, other resuscitative drugs (see OVERDOSAGE). ...
Effects of different doses of venlafaxine on serotonin and
... mental disorders. Subjects were excluded from the study for any of the following reasons : (1) use of an investigational drug within 30 d of study entry ; (2) orthostatic hypotension (a fall in systolic BP>10 mmHg) ; (3) use of any psychotropic medication or any illicit drug ; (4) regular use of any ...
... mental disorders. Subjects were excluded from the study for any of the following reasons : (1) use of an investigational drug within 30 d of study entry ; (2) orthostatic hypotension (a fall in systolic BP>10 mmHg) ; (3) use of any psychotropic medication or any illicit drug ; (4) regular use of any ...
Site-specific conjugation of a cytotoxic drug to an antibody improves
... safety profiles8,20. In a study that underscored the consequences of this heterogeneity, researchers purified ADC fractions with exactly two, four or eight drugs attached to each antibody and compared these fractions for in vivo efficacy, tolerability in mice and pharmacokinetics8. The most heavily ...
... safety profiles8,20. In a study that underscored the consequences of this heterogeneity, researchers purified ADC fractions with exactly two, four or eight drugs attached to each antibody and compared these fractions for in vivo efficacy, tolerability in mice and pharmacokinetics8. The most heavily ...
... group in table 1. Figure 4 shows the corresponding time course for MAP. Before the administration of the drugs, there was no significant difference in MAP between groups (table 1). After instillation i.t., there was no significant variance in AUC for the five-hour observation period (AUC1–5 h of MAP ...
Fentanyl Data Sheet Oct 13
... There are no adequate data from the use of fentanyl in pregnant women. Studies in animals have shown some reproductive toxicity. The potential risk for humans is unknown. In vitro fentanyl, like other opioid analgesics, showed mutagenic effects in a mammalian cell culture assay, only at cytotoxic co ...
... There are no adequate data from the use of fentanyl in pregnant women. Studies in animals have shown some reproductive toxicity. The potential risk for humans is unknown. In vitro fentanyl, like other opioid analgesics, showed mutagenic effects in a mammalian cell culture assay, only at cytotoxic co ...
A Practitioner`s Handbook Of Materia Medica And Therapeutics The
... large dose most active drugs may be classed as poisons to a certain degree and that most poisons act upon a narrow area in minute doses but extend this area in large doses. This proposition cannot be too strongly emphasized, and certainly if our therapeutics is ever to become direct and definite, we ...
... large dose most active drugs may be classed as poisons to a certain degree and that most poisons act upon a narrow area in minute doses but extend this area in large doses. This proposition cannot be too strongly emphasized, and certainly if our therapeutics is ever to become direct and definite, we ...
Xenazine® 25 mg
... tetrabenazine is being considered for a patient with previously detected breast cancer. Although amenorrhea, galactorrhea, gynecomastia and impotence can be caused by elevated serum concentrations, the clinical significance of elevated serum prolactin concentrations for most patients is unknown. Chr ...
... tetrabenazine is being considered for a patient with previously detected breast cancer. Although amenorrhea, galactorrhea, gynecomastia and impotence can be caused by elevated serum concentrations, the clinical significance of elevated serum prolactin concentrations for most patients is unknown. Chr ...
Martindale: The Complete Drug Reference
... 1. 1. Katta R, Anusuri V. Serum sickness-like reaction to cefuroxime: a case report and review of the literature. J Drugs Dermatol 2007; 6: 747–8. PubMed 2. 2. Varela Losada S, et al. Immediate-type allergic reaction to cefuroxime: crossreactivity with other cephalosporins, and good tolerance to cef ...
... 1. 1. Katta R, Anusuri V. Serum sickness-like reaction to cefuroxime: a case report and review of the literature. J Drugs Dermatol 2007; 6: 747–8. PubMed 2. 2. Varela Losada S, et al. Immediate-type allergic reaction to cefuroxime: crossreactivity with other cephalosporins, and good tolerance to cef ...
Effects of Phentermine on Responding Maintained under Multiple
... treatments can be developed that will decrease cocaine abuse in humans. One approach to assessing this possibility is to test potential treatments on behaviors associated with the abuse potential of cocaine (Woolverton and Kleven, 1991). A number of reports have shown that cocaine self-administratio ...
... treatments can be developed that will decrease cocaine abuse in humans. One approach to assessing this possibility is to test potential treatments on behaviors associated with the abuse potential of cocaine (Woolverton and Kleven, 1991). A number of reports have shown that cocaine self-administratio ...
Effects of Phentermine on Responding Maintained under Multiple
... treatments can be developed that will decrease cocaine abuse in humans. One approach to assessing this possibility is to test potential treatments on behaviors associated with the abuse potential of cocaine (Woolverton and Kleven, 1991). A number of reports have shown that cocaine self-administratio ...
... treatments can be developed that will decrease cocaine abuse in humans. One approach to assessing this possibility is to test potential treatments on behaviors associated with the abuse potential of cocaine (Woolverton and Kleven, 1991). A number of reports have shown that cocaine self-administratio ...
HUMAN PHARMACOLOGY AYAHUASCA Director de la Tesi:
... some areas of Ecuador and Colombia, this psychotropic tea is also known by many other vernacular names. The term caapi is employed in the river Vaupés, yajé or yagé in southern Colombia, Daime or Hoasca in Brazil, natema in Ecuador and pinde along the Pacific coast of Colombia. More than 70 indigeno ...
... some areas of Ecuador and Colombia, this psychotropic tea is also known by many other vernacular names. The term caapi is employed in the river Vaupés, yajé or yagé in southern Colombia, Daime or Hoasca in Brazil, natema in Ecuador and pinde along the Pacific coast of Colombia. More than 70 indigeno ...
Hormesis
Hormesis (from Greek hórmēsis ""rapid motion, eagerness,"" from ancient Greek hormáein ""to set in motion, impel, urge on"") is the term for generally favorable biological responses to low exposures to toxins and other stressors. A pollutant or toxin showing hormesis thus has the opposite effect in small doses as in large doses. A related concept is Mithridatism, which refers to the willful exposure to toxins in an attempt to develop immunity against them. Hormetics is the term proposed for the study and science of hormesis.In toxicology, hormesis is a dose response phenomenon characterized by a low dose stimulation, high dose inhibition, resulting in either a J-shaped or an inverted U-shaped dose response. Such environmental factors that would seem to produce positive responses have also been termed ""eustress.""The hormesis model of dose response is vigorously debated. The notion that hormesis is important for chemical risks regulations is not widely accepted.The biochemical mechanisms by which hormesis works are not well understood. It is conjectured that low doses of toxins or other stressors might activate the repair mechanisms of the body. The repair process fixes not only the damage caused by the toxin, but also other low-level damage that might have accumulated before without triggering the repair mechanism.