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PG12-12 Mairs Lay summary Principal Investigator: Dr Rob Mairs
... Although radiotherapy is widely used in the clinical management of prostate cancer patients, damage to neighbouring normal organs limits the radiation dose which can be delivered. Significantly, there is no curative treatment for prostate cancer that has spread. Targeted radiotherapy using [131I]Tro ...
... Although radiotherapy is widely used in the clinical management of prostate cancer patients, damage to neighbouring normal organs limits the radiation dose which can be delivered. Significantly, there is no curative treatment for prostate cancer that has spread. Targeted radiotherapy using [131I]Tro ...
Morphine Facts and Tips
... How is it used? Oral (PO): route of choice; 30mg=10mg IM in repeated doses because first pass effect of hepatic metabolism (portal circulation from the gut goes to liver where part of the dose is metabolized); immediate release preparations are effective for breakthrough pain to titrate doses and fo ...
... How is it used? Oral (PO): route of choice; 30mg=10mg IM in repeated doses because first pass effect of hepatic metabolism (portal circulation from the gut goes to liver where part of the dose is metabolized); immediate release preparations are effective for breakthrough pain to titrate doses and fo ...
vancomycin (van-koe-mye-sin) - DavisPlus
... Monitor intake and output ratios and daily weight. Cloudy or pink urine may be a sign of nephrotoxicity. Assess patient for signs of superinfection (black, furry overgrowth on tongue; vaginal itching or discharge; loose or foul-smelling stools). Report occurrence. Observe patient for signs and sympt ...
... Monitor intake and output ratios and daily weight. Cloudy or pink urine may be a sign of nephrotoxicity. Assess patient for signs of superinfection (black, furry overgrowth on tongue; vaginal itching or discharge; loose or foul-smelling stools). Report occurrence. Observe patient for signs and sympt ...
Fentanyl Citrate - Verde Valley Emergency Medical Services
... Be careful not to break ampule……lots of paperwork required with DHS and DEA! This is a class II drug. If ampule is broken. It must be reported to Tish Arwine and VVMC Pharmacy that day- along with written documentation and witness if ...
... Be careful not to break ampule……lots of paperwork required with DHS and DEA! This is a class II drug. If ampule is broken. It must be reported to Tish Arwine and VVMC Pharmacy that day- along with written documentation and witness if ...
Buccal Midazolam Supporting Guideline v1
... This may need to be given in a community setting. If the patient has never been given buccal midazolam (or a similar nasal, buccal, or intravenous benzodiazepine) before, the parents or carers may have been advised to call the emergency services (Ambulance or Para-medic) once the dose is given in ca ...
... This may need to be given in a community setting. If the patient has never been given buccal midazolam (or a similar nasal, buccal, or intravenous benzodiazepine) before, the parents or carers may have been advised to call the emergency services (Ambulance or Para-medic) once the dose is given in ca ...
UV Radiation and Air Quality in the Parks
... reaching the parks is an area of special concern. Since the 1970s, ozone high in the atmosphere has been decreasing. This allows more ultraviolet (UV) radiation to reach the earth's surface, and the effects of this increased UV radiation are not well known. Scientists with the National Park Service, ...
... reaching the parks is an area of special concern. Since the 1970s, ozone high in the atmosphere has been decreasing. This allows more ultraviolet (UV) radiation to reach the earth's surface, and the effects of this increased UV radiation are not well known. Scientists with the National Park Service, ...
Document
... recommended for central nervous system HIV disease, dosing at the lower end may be preferred is settings where anaemia is prevalent. Needed as a priority product despite well recognised longer term toxicities (lipodystrophy), as it is initially well tolerated, is safer to use in anaemia than AZT, an ...
... recommended for central nervous system HIV disease, dosing at the lower end may be preferred is settings where anaemia is prevalent. Needed as a priority product despite well recognised longer term toxicities (lipodystrophy), as it is initially well tolerated, is safer to use in anaemia than AZT, an ...
Radiation Exposure of Medical Staff in Interventional Radiology
... skin injuries were associated with transjugular intrahepatic portosystemic shunt (TIPS) creation, renal angioplasty, multiple hepatic/biliary procedures, or embolization [1, 3, 6–9]. In all patients the risk of a cancer from the exposure is not a major concern when compared to the benefits of the pr ...
... skin injuries were associated with transjugular intrahepatic portosystemic shunt (TIPS) creation, renal angioplasty, multiple hepatic/biliary procedures, or embolization [1, 3, 6–9]. In all patients the risk of a cancer from the exposure is not a major concern when compared to the benefits of the pr ...
Revised: September 2012 AN: 00730/2012 SUMMARY OF
... To be given strictly by intramuscular injection, behind the ear. A long hypodermic needle should be used and the injection given as closely behind the ear as possible and perpendicular to the skin. There is a risk of injecting part of the drug into the fat, if heavy animals are injected with a short ...
... To be given strictly by intramuscular injection, behind the ear. A long hypodermic needle should be used and the injection given as closely behind the ear as possible and perpendicular to the skin. There is a risk of injecting part of the drug into the fat, if heavy animals are injected with a short ...
Initial Dosing and Clinical Titration of Antipsychotic Drugs in
... than 65%, whereas EPS are associated with occupancy greater than about 80 percent.3’ 4 Excessive doses of conventional agents may be associated with poorer clinical outcome, as antipsychotic effects are unlikely to improve above an optimal therapeutic dose range, possibly causing secondary negative ...
... than 65%, whereas EPS are associated with occupancy greater than about 80 percent.3’ 4 Excessive doses of conventional agents may be associated with poorer clinical outcome, as antipsychotic effects are unlikely to improve above an optimal therapeutic dose range, possibly causing secondary negative ...
Diagnostic and Therapeutic Pitfalls in Myasthenia Gravis
... “For patients with non-thymomatous autoimmune MG, thymectomy is recommended as an option to increase the ...
... “For patients with non-thymomatous autoimmune MG, thymectomy is recommended as an option to increase the ...
Barbiturates - Anesthesia Slides, Presentations and Publications by
... “neuroprotective” properties secondary to their ability to decrease oxygen demand. Alternative explanations have been suggested, including a reverse steal (“Robin Hood effect”) on CBF, ...
... “neuroprotective” properties secondary to their ability to decrease oxygen demand. Alternative explanations have been suggested, including a reverse steal (“Robin Hood effect”) on CBF, ...
BETAHISTINE HYDROCHL ORIDE
... It is now known whether betahistine is excreted in human breast milk. The benefits of the drug to the mother should be weighed against the potential risk to the baby when considering betahistine treatment. Children The safety and efficacy of betahistine in pediatric patients less than 18 years old h ...
... It is now known whether betahistine is excreted in human breast milk. The benefits of the drug to the mother should be weighed against the potential risk to the baby when considering betahistine treatment. Children The safety and efficacy of betahistine in pediatric patients less than 18 years old h ...
(PK) of LOXO-101 During the First-in-Human
... dosing, the AUC between 0 and 12 hours was calculated by log-linear extrapolation of the measured concentrations at 6 and 8 hours through 12 hours. The extrapolated AUC was 9% of the AUC in all cases. For BID dosing, AUC0-24 was calculated as 2 x AUC0-12. ...
... dosing, the AUC between 0 and 12 hours was calculated by log-linear extrapolation of the measured concentrations at 6 and 8 hours through 12 hours. The extrapolated AUC was 9% of the AUC in all cases. For BID dosing, AUC0-24 was calculated as 2 x AUC0-12. ...
New anticancer compounds could boost effectiveness of standard
... developing new small molecules that could work synergistically with currently available anticancer drugs and radiation therapies to inhibit tumor growth and enhance survival rates for many types of cancer, potentially without increasing toxicity. The inspiration for Lixte came from Kovach’s interest ...
... developing new small molecules that could work synergistically with currently available anticancer drugs and radiation therapies to inhibit tumor growth and enhance survival rates for many types of cancer, potentially without increasing toxicity. The inspiration for Lixte came from Kovach’s interest ...
NOVERIL 240 MG TABLETS
... the need to monitor patients for the emergence of other psychiatric symptoms (see section 4.8 Undesirable effects), as well as the emergence of suicidality, and to report such symptoms immediately to health care providers [2]. Prescriptions for Noveril should be written for the smallest quantity of ...
... the need to monitor patients for the emergence of other psychiatric symptoms (see section 4.8 Undesirable effects), as well as the emergence of suicidality, and to report such symptoms immediately to health care providers [2]. Prescriptions for Noveril should be written for the smallest quantity of ...
Nuclear Instrumentation: PHYS 561 Spring 2015 Schedule Number
... Course Overview Description from the Official Course Catalog: Radiation detection, measurement and spectroscopy. Ionization chambers, GM and proportional counters, scintillation and semiconductor detectors, and thermoluminescent dosimetry. Description of the Purpose and Course Content: This course c ...
... Course Overview Description from the Official Course Catalog: Radiation detection, measurement and spectroscopy. Ionization chambers, GM and proportional counters, scintillation and semiconductor detectors, and thermoluminescent dosimetry. Description of the Purpose and Course Content: This course c ...
Veterinary Cardiorespiratory Centre
... pericardial effusion), ie. reduction in the congestion (volume overload) and inhibition of the neuroendocrine responses that are induced. Rest is important. Caged rest alone will often improve the clinical condition of animals in congestive heart failure. With outpatients, all animals in CHF should ...
... pericardial effusion), ie. reduction in the congestion (volume overload) and inhibition of the neuroendocrine responses that are induced. Rest is important. Caged rest alone will often improve the clinical condition of animals in congestive heart failure. With outpatients, all animals in CHF should ...
Beta-Blocker Tips in Heart Failure
... Unable to carry out any physical activity without discomfort: symptoms of fatigue, chest pain, palpitations, or dyspnea are present even at rest, with increased discomfort with any physical activity ...
... Unable to carry out any physical activity without discomfort: symptoms of fatigue, chest pain, palpitations, or dyspnea are present even at rest, with increased discomfort with any physical activity ...
1020 KB 2017 Practical Strategies for Treatment
... remission after two well-established antidepressant treatment trials known to have been of evidence-based acceptable dose and duration Develops in about 30% of patients with MDD (Greden et al, 2011) ...
... remission after two well-established antidepressant treatment trials known to have been of evidence-based acceptable dose and duration Develops in about 30% of patients with MDD (Greden et al, 2011) ...
Flupentixol+Melitracen
... impairment, cardiovascular disease, hypotension, parkinson's disease, epilepsy, thyroid disease, myasthenia gravis, prostatic hypertrophy, severe respiratory disease, history of jaundice, blood dyscrasias ii. history of urinary retention, concurrent electroconvulsive therapy iii. elderly, who are pa ...
... impairment, cardiovascular disease, hypotension, parkinson's disease, epilepsy, thyroid disease, myasthenia gravis, prostatic hypertrophy, severe respiratory disease, history of jaundice, blood dyscrasias ii. history of urinary retention, concurrent electroconvulsive therapy iii. elderly, who are pa ...
Pharmacy Update on Dose Optimization Program
... Pharmacy Update on Dose Optimization Program Effective 11/6/2014, the Medicaid fee-for-service (FFS) program will be updating the Dose Optimization Program in the following therapeutic classes. The NYS Department of Health has classified drugs to be added in this program, the majority of which have ...
... Pharmacy Update on Dose Optimization Program Effective 11/6/2014, the Medicaid fee-for-service (FFS) program will be updating the Dose Optimization Program in the following therapeutic classes. The NYS Department of Health has classified drugs to be added in this program, the majority of which have ...
C22_Davidson
... • 383 children born in NY state cared for by Medicaid that had a hernia repair < 3yrs of age • 5050 randomly selected controls matched on age • Adjusted for age, gender, race and presence of complicating diagnoses at birth • Behavioral or developmental disorder – 17 in hernia group (4.4%) – 59 in no ...
... • 383 children born in NY state cared for by Medicaid that had a hernia repair < 3yrs of age • 5050 randomly selected controls matched on age • Adjusted for age, gender, race and presence of complicating diagnoses at birth • Behavioral or developmental disorder – 17 in hernia group (4.4%) – 59 in no ...
Case Study 2 Ruth Brown - KCHFT Omitted dose
... Twice daily delivery requested in tender specification for new supplier of medicines to hospitals ...
... Twice daily delivery requested in tender specification for new supplier of medicines to hospitals ...
Hormesis
Hormesis (from Greek hórmēsis ""rapid motion, eagerness,"" from ancient Greek hormáein ""to set in motion, impel, urge on"") is the term for generally favorable biological responses to low exposures to toxins and other stressors. A pollutant or toxin showing hormesis thus has the opposite effect in small doses as in large doses. A related concept is Mithridatism, which refers to the willful exposure to toxins in an attempt to develop immunity against them. Hormetics is the term proposed for the study and science of hormesis.In toxicology, hormesis is a dose response phenomenon characterized by a low dose stimulation, high dose inhibition, resulting in either a J-shaped or an inverted U-shaped dose response. Such environmental factors that would seem to produce positive responses have also been termed ""eustress.""The hormesis model of dose response is vigorously debated. The notion that hormesis is important for chemical risks regulations is not widely accepted.The biochemical mechanisms by which hormesis works are not well understood. It is conjectured that low doses of toxins or other stressors might activate the repair mechanisms of the body. The repair process fixes not only the damage caused by the toxin, but also other low-level damage that might have accumulated before without triggering the repair mechanism.