Homework Assignment #1
... 1. (2 pts) Promoters for protein-coding genes in eukaryotic cells contain a basal promoter element that is recognized by RNA polymerase II and a collection of basal transcription factors (e.g., TFIID, TFIIB). However, the basal activity of the promoter by itself is very low and is invariably influen ...
... 1. (2 pts) Promoters for protein-coding genes in eukaryotic cells contain a basal promoter element that is recognized by RNA polymerase II and a collection of basal transcription factors (e.g., TFIID, TFIIB). However, the basal activity of the promoter by itself is very low and is invariably influen ...
Datamining Methods - ILRI Research Computing
... The default values of how the heatmap performs clustering can be changed by creating new functions that calculate distance and also perform clustering. ...
... The default values of how the heatmap performs clustering can be changed by creating new functions that calculate distance and also perform clustering. ...
Chapter 20 - Biotechnology
... By doing more mixing and matching of modular elements, humans - and vertebrates in general - reach more complexity than flies or worms. – The typical human gene probably specifies at least two or three different polypeptides by using different combinations of exons. • Along with this is additional p ...
... By doing more mixing and matching of modular elements, humans - and vertebrates in general - reach more complexity than flies or worms. – The typical human gene probably specifies at least two or three different polypeptides by using different combinations of exons. • Along with this is additional p ...
Proximal promoter
... Approximately -34 A binding site for RNA polymerase General transcription factor binding sites ...
... Approximately -34 A binding site for RNA polymerase General transcription factor binding sites ...
Genome duplication, divergent resolution and
... clusters as, for example, humans. Additional evidence favouring the fish-specific genome duplication hypothesis comes from comparative mapping studies, which have identified a large number of mammalian genes with two zebrafish ‘co-orthologs’19–21. Furthermore, most of these zebrafish co-orthologs ar ...
... clusters as, for example, humans. Additional evidence favouring the fish-specific genome duplication hypothesis comes from comparative mapping studies, which have identified a large number of mammalian genes with two zebrafish ‘co-orthologs’19–21. Furthermore, most of these zebrafish co-orthologs ar ...
document
... The Insertion sequences and their composite elements TYPE I The Tn3 family of elements TYPE II The transposing bacteriophages (e.g. mu - not covered here) TYPE III The conjugative transposons (e.g. Tn916 carrying tet resistance around a range of host cells in Enterococcus and other bacteria). Large ...
... The Insertion sequences and their composite elements TYPE I The Tn3 family of elements TYPE II The transposing bacteriophages (e.g. mu - not covered here) TYPE III The conjugative transposons (e.g. Tn916 carrying tet resistance around a range of host cells in Enterococcus and other bacteria). Large ...
doc - Berkeley Statistics
... Mendel’s theory shows the power of simple chance models in action. In 1865, Gregor Mendel published an article which provided a scientific explanation for heredity, and eventually caused a revolution in biology. By a curious twist of fortune, this paper was ignored for about thirty years, until the ...
... Mendel’s theory shows the power of simple chance models in action. In 1865, Gregor Mendel published an article which provided a scientific explanation for heredity, and eventually caused a revolution in biology. By a curious twist of fortune, this paper was ignored for about thirty years, until the ...
1. A 6-frame translation map of a segment of DNA is shown, with
... Transcription goes right-to-left through ORF B (because the Crick strand is the coding strand) so, the RNA transcripts will be smallest at the right (where transcription has just begun) and longest at the left (where it is about to end). For ORF C/D (Watson strand is coding) the situation reversed. ...
... Transcription goes right-to-left through ORF B (because the Crick strand is the coding strand) so, the RNA transcripts will be smallest at the right (where transcription has just begun) and longest at the left (where it is about to end). For ORF C/D (Watson strand is coding) the situation reversed. ...
DNA and the Genome - Speyside High School
... Splice site mutations RNA splicing is important in creating the mature mRNA transcript. Mutations in the area that marks the start or end of an intron, may lead to one or more introns not being removed. This will lead to a creation of a protein that does not function properly. CFE Higher Biology ...
... Splice site mutations RNA splicing is important in creating the mature mRNA transcript. Mutations in the area that marks the start or end of an intron, may lead to one or more introns not being removed. This will lead to a creation of a protein that does not function properly. CFE Higher Biology ...
Additional File 2, Figure 1 - Comparison of
... genome. Out of this we excluded 5,850 gene models as they had less than 5 probes and/or had less than 45% of the total number of expected probes. As explained before for Arabidopsis, we considered the locus to be transcribed if at least one of the gene models has a p-value less than 0.05 [2]. Out of ...
... genome. Out of this we excluded 5,850 gene models as they had less than 5 probes and/or had less than 45% of the total number of expected probes. As explained before for Arabidopsis, we considered the locus to be transcribed if at least one of the gene models has a p-value less than 0.05 [2]. Out of ...
Genetica per Scienze Naturali aa 05
... In the latter case, nearly all sequence positions are the same simply because not enough time has elapsed since the last common ancestor for large numbers of changes to have occurred. In contrast, because of functional constraints in human-mouse comparisons the exons in genes stand out as small isla ...
... In the latter case, nearly all sequence positions are the same simply because not enough time has elapsed since the last common ancestor for large numbers of changes to have occurred. In contrast, because of functional constraints in human-mouse comparisons the exons in genes stand out as small isla ...
Heterochromatin-2015
... CTCF establishes domains in which genes are coregulated and targets regulatory sequences to their promoters ...
... CTCF establishes domains in which genes are coregulated and targets regulatory sequences to their promoters ...
Review: RECOMB Satellite Workshop on Regulatory Genomics
... and then only doles them out to a relatively narrow bunch of people who have enough money to pay for them..solely to promote the financial health of the ...
... and then only doles them out to a relatively narrow bunch of people who have enough money to pay for them..solely to promote the financial health of the ...
Title Page, Table of Contents and Background
... 8. You can quickly see information about what is known about the genome of your organism from the genome statistics page. For example, as is shown in Figure 15, the genome of Listeria monocytogenes 08-5578 has approximately 3.1 x 106 nucleotides ( see ”DNA, total number of bases”) and the percentage ...
... 8. You can quickly see information about what is known about the genome of your organism from the genome statistics page. For example, as is shown in Figure 15, the genome of Listeria monocytogenes 08-5578 has approximately 3.1 x 106 nucleotides ( see ”DNA, total number of bases”) and the percentage ...
Inferring Function From Known Genes
... used to infer the function of unknown genes in a microarray experiment. 3) Pathway analysis If the genes are sufficiently well understood, they may be assembled into networks showing which genes regulate other genes. Unknown genes that have expression patterns similar to those in the network can be ...
... used to infer the function of unknown genes in a microarray experiment. 3) Pathway analysis If the genes are sufficiently well understood, they may be assembled into networks showing which genes regulate other genes. Unknown genes that have expression patterns similar to those in the network can be ...
Inferring Function From Known Genes
... used to infer the function of unknown genes in a microarray experiment. 3) Pathway analysis If the genes are sufficiently well understood, they may be assembled into networks showing which genes regulate other genes. Unknown genes that have expression patterns similar to those in the network can be ...
... used to infer the function of unknown genes in a microarray experiment. 3) Pathway analysis If the genes are sufficiently well understood, they may be assembled into networks showing which genes regulate other genes. Unknown genes that have expression patterns similar to those in the network can be ...
tRNAs and ribosomal RNAs?
... probe to identifjr adjacent sequences would hybridize to many non-o clones. Such repetitive sequences could noi be used in a chromos since the repeated sequence would be present in many different gena locations and it would be impossible to determine which was the correct one. ...
... probe to identifjr adjacent sequences would hybridize to many non-o clones. Such repetitive sequences could noi be used in a chromos since the repeated sequence would be present in many different gena locations and it would be impossible to determine which was the correct one. ...
GENE EXPRESSION ANALYSIS
... including experimental design and normalisation strategies. Xelect offers a complete and confidential gene expression service at very competitive prices. The genomes of salmonids have undergone two rounds of whole genome duplication (WGD) relative to their last common ancestor with humans. Around 15 ...
... including experimental design and normalisation strategies. Xelect offers a complete and confidential gene expression service at very competitive prices. The genomes of salmonids have undergone two rounds of whole genome duplication (WGD) relative to their last common ancestor with humans. Around 15 ...
p53
... shortens with each round of replication and they bind to proteins that protect the ends of chromosomes from degradation and fusion with other chromosomes. ...
... shortens with each round of replication and they bind to proteins that protect the ends of chromosomes from degradation and fusion with other chromosomes. ...
PowerPoint File
... Most ~ 50 bp but can be > 15 kb Large genes – large introns Small genes – small introns Size differs between species C. elegans 267 bp Drosophila 487 bp Human 3,365 bp Human introns > exons in size ...
... Most ~ 50 bp but can be > 15 kb Large genes – large introns Small genes – small introns Size differs between species C. elegans 267 bp Drosophila 487 bp Human 3,365 bp Human introns > exons in size ...
Identification of disease genes Mutational analyses Monogenic
... Two independent non-consanguineous individuals —> 4 mutations in the same gene If large consanguineous families with high LOD score, two families (mutations) may be sufficient. If only ONE large consanguineous family with high LOD score, there is a need to demonstrate that the mutation causes a loss ...
... Two independent non-consanguineous individuals —> 4 mutations in the same gene If large consanguineous families with high LOD score, two families (mutations) may be sufficient. If only ONE large consanguineous family with high LOD score, there is a need to demonstrate that the mutation causes a loss ...
GoFigure: Automated Gene Ontology annotation
... many biologists will derive no information about its function from the name. However, inspection of the molecular function graph suggests that Hensin is a scavenger receptor that may also contain peptidase activity. While these results do not replace an exhaustive literature search, they may help th ...
... many biologists will derive no information about its function from the name. However, inspection of the molecular function graph suggests that Hensin is a scavenger receptor that may also contain peptidase activity. While these results do not replace an exhaustive literature search, they may help th ...
Chapter 15
... 1. Promoter always capable of binding to RNA polymerase and therefore the genes in question are always transcribed (“on”) >genes that are always on are called constitutive genes 2. Promoter usually incapable of binding to RNA polymerase and therefore the genes are usually not transcribed (“off”) but ...
... 1. Promoter always capable of binding to RNA polymerase and therefore the genes in question are always transcribed (“on”) >genes that are always on are called constitutive genes 2. Promoter usually incapable of binding to RNA polymerase and therefore the genes are usually not transcribed (“off”) but ...
Transposable element
A transposable element (TE or transposon) is a DNA sequence that can change its position within the genome, sometimes creating or reversing mutations and altering the cell's genome size. Transposition often results in duplication of the TE. Barbara McClintock's discovery of these jumping genes earned her a Nobel prize in 1983.TEs make up a large fraction of the C-value of eukaryotic cells. There are at least two classes of TEs: class I TEs generally function via reverse transcription, while class II TEs encode the protein transposase, which they require for insertion and excision, and some of these TEs also encode other proteins. It has been shown that TEs are important in genome function and evolution. In Oxytricha, which has a unique genetic system, they play a critical role in development. They are also very useful to researchers as a means to alter DNA inside a living organism.