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Processing the RefSeq and CCDS Annotation Datasets Using the SAS System: Creation of Gene Reference
Processing the RefSeq and CCDS Annotation Datasets Using the SAS System: Creation of Gene Reference

... but the number of bases is 50000 (50000-1+1). The variable P (Line 42) is the absolute position of the base in the reference chromosome sequence. It is the same as __POINT, but since __POINT is used in the POINT= option to the SET statement, it is not allowed to be in the output data set. Each time ...
Depolarization of the actin cytoskeleton is a specific phenotype in
Depolarization of the actin cytoskeleton is a specific phenotype in

... (Chowdhury et al., 1992; Lillie and Brown, 1994; Novick et ...
rec-mediated recombinational hot spot activity in bacteriophage
rec-mediated recombinational hot spot activity in bacteriophage

... are termed “hot spot survey crosses.” These crosses are carried out using conditions which block nearly all DNA synthesis (MCMILINand Russo 1972). Though there is some residual DNA synthesis, which is potentially very interesting (J. SIEGEL,nianuscript in preparation), it is convenient and justifiab ...
The Microbial Ecology of Dental Caries - Co
The Microbial Ecology of Dental Caries - Co

... The microbial ecology of caries is complex and incorporates mechanisms common to the natural colonization of the host and to plaque accumulation at sites that do not develop caries lesions. It is not simply accumulation of plaque in the oral cavity but also the ecology of oral bacteria among the hos ...
View PDF
View PDF

... outbreaks in a variety of clinical settings. It showing resistance to glycopeptides have now been reported from many parts of the world and show heterogeneity, both phenotypic and genotypic [2]. Emerging risk factors for a massive bacterial colonization include the increased life expectancy of the g ...
DNA
DNA

... information located on the chromosomes and consisting of DNA. • Genotype: The genetic makeup of an organism • Phenotype: the physical expressed traits of an organism • Nucleic acids: Biological molecules (RNA and DNA) that allow organisms to reproduce ...
Exclusion of known corneal dystrophy genes in an autosomal
Exclusion of known corneal dystrophy genes in an autosomal

Robust gene silencing mediated by antisense small RNAs in the
Robust gene silencing mediated by antisense small RNAs in the

... trigger-gene fusion and is maintained despite loss of the trigger plasmid. We used this approach to silence multiple amebic genes, including an E. histolytica Myb gene, which is upregulated during oxidative stress response. Silencing of the EhMyb gene decreased parasite viability under oxidative str ...
Presence of multiple group I introns closely 23S rRNAs of lichen-forming
Presence of multiple group I introns closely 23S rRNAs of lichen-forming

... subgroup introns featured the loop of the P8 helix; the IA3 and IB4 subgroups featured an extension from the peripheral loops towards the intron core structure. More importantly, all of these putative proteins contained one LAGLIDADG motif, identified by using Pfam v21.10 [17], characteristic of the ...
ARTICLES - Weizmann Institute of Science
ARTICLES - Weizmann Institute of Science

... to bend sharply, as required by the nucleosome structure. However, it is not known whether these sequence preferences have a significant influence on nucleosome position in vivo, and thus regulate the access of other proteins to DNA. Here we isolated nucleosome-bound sequences at high resolution fro ...
PERSPECTIVES IN HUMAN GENETICS Mendelian Inheritance in
PERSPECTIVES IN HUMAN GENETICS Mendelian Inheritance in

... www.ajhg.org ...
Selection in backcross programmes
Selection in backcross programmes

Opsin genes, cone photopigments, color vision, and color blindness
Opsin genes, cone photopigments, color vision, and color blindness

... restriction endonuclease Alu I that cleaves it. The sequence occurs in about 300,000 copies in the human genome and is believed to have no coding value. An Alu repeat element at the site of insertion of the duplicated opsin gene may have been important in promoting crossing over within the array. ...
24 Recombination Hotspots in Nonallelic Homologous Recombination
24 Recombination Hotspots in Nonallelic Homologous Recombination

... recombinant haplotypes (spanning <10 kb) against a background of thousands of nonrecombinant haplotypes renders it difficult to expand the initial locus-specific studies of recombination rate heterogeneity across the whole genome. More recently, a new class of statistical methods have been devised t ...
SelectedJournalAsthm..
SelectedJournalAsthm..

... Daniels SE, Bhattacharrya S, James A, et al. A genome-wide search for quantitative trait loci underlying asthma. Nature 1996;383:247-50. Dizier MH, Besse-Schmittler C, Guilloud-Bataille M, et al. Genome screen for asthma and related phenotypes in the French EGEA study. Am J Respir Crit Care Med 2000 ...
Plant speciation through chromosome instability and ploidy change
Plant speciation through chromosome instability and ploidy change

Universal chloroplast integration and expression vectors
Universal chloroplast integration and expression vectors

... The invention provides universal chloroplast integration and expression vectors which are competent to stably transform and integrate genes of interest into chloroplast genome of multiple species of plants. Transformed plants and their progeny are provided. Monocotyledonous and dicotyledonous plants ...
A Comparative Study on the Recovery of EcoRI Endonuclease from
A Comparative Study on the Recovery of EcoRI Endonuclease from

... prevent the overgrowth of plasmid-free cells that do not have the ability to synthesise the product. Ten ml of pre-culture was used to inoculate sterile 1L LB medium and then placed in the orbital shaker at the specified temperatures for each E. coli strain. The E. coli M5248 strain was first transf ...
Reproductive isolation and introgression between sympatric
Reproductive isolation and introgression between sympatric

... Here, we investigate the interplay between species divergence and ongoing introgression in sympatric Mimulus species. We focus on populations of M. guttatus and M. nasutus that co-occur at Catherine Creek (CAC), a site in the Columbia River Gorge where we recently discovered evidence for substantial ...
Identification and Isolation of Dominant Susceptibility Loci for
Identification and Isolation of Dominant Susceptibility Loci for

... To produce linkage maps covering the complete genome, all 650 of the backcross progeny were genotyped using 236 markers, resulting in a dense map with an average distance of 6.8 ⫾ 5.0 cM and maximal intramarker distance of 19.8 cM. All autosomal chromosomes were analyzed, whereas the analysis of the ...
WASP - Genome Institute, BIOTEC
WASP - Genome Institute, BIOTEC

Y11 Revision material - Biology - Whitworth Community High School
Y11 Revision material - Biology - Whitworth Community High School

... Describe ​the difference between monocular and binocular vision. Describe ​the most common vision problems. Name ​and ​locate ​the main parts of the nervous system. Describe ​nerve impulses. Describe ​reflex actions. □ Recognise ​that voluntary responses are under the conscious control of the brain. ...
A Novel CpG Island Set Identifies Tissue-Specific
A Novel CpG Island Set Identifies Tissue-Specific

... DNA methylation in the mammalian genome arises due to covalent addition of a methyl group to the 59 position of cytosine in the context of the palindromic dinucleotide, CpG. This modification is established and maintained by a family of DNA methyltransferases that are essential for development and vi ...
Table of Contents - Scholars` Bank
Table of Contents - Scholars` Bank

... certain shape that dictates the protein’s function. The process of protein formation begins with a cell's database, its DNA. DNA stores information concerning how a cell functions and about the proteins needed to carry this out. DNA is made from building blocks called nucleotides, of which there are ...
Probable presence of an ubiquitous cryptic mitochondrial gene on
Probable presence of an ubiquitous cryptic mitochondrial gene on

... polymorphisms in tRNA genes and the cloverleaf formation of the antisense tRNA sequences [25]. Pathogenic mutations, when compared to neutral polymorphisms, decrease cloverleaf formation in antisense tRNAs that are predicted to be active in translation according to other properties and analyses [24] ...
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Pathogenomics

Pathogen infections are among the leading causes of infirmity and mortality among humans and other animals in the world. Until recently, it has been difficult to compile information to understand the generation of pathogen virulence factors as well as pathogen behaviour in a host environment. The study of Pathogenomics attempts to utilize genomic and metagenomics data gathered from high through-put technologies (e.g. sequencing or DNA microarrays), to understand microbe diversity and interaction as well as host-microbe interactions involved in disease states. The bulk of pathogenomics research concerns itself with pathogens that affect human health; however, studies also exist for plant and animal infecting microbes.
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