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Evolution of synonymous codon usage in metazoans Laurent Duret
Evolution of synonymous codon usage in metazoans Laurent Duret

miRNA pptx - NUS School of Computing
miRNA pptx - NUS School of Computing

... use the expression level of a known target genes for that specific intergenic miRNA If its target genes are consistently down-regulated, then we can assume that the expression level of the intergenic miRNA gene is up-regulated ...
Genetic identification of eleven aquatic bacteria using the 16S rDNA
Genetic identification of eleven aquatic bacteria using the 16S rDNA

... (Reference sequence) are used to compare gene sequences for identification and to study phylogeny and taxonomy. For example, Entrez nucleotide library which works with BLAST (Basic Local Alignment Search Tool), have 1,965,631 partial 16S rRNA partial genes available for genetic identification. When ...
as a PDF
as a PDF

... coefficient [21,22]. If the antagonistic effects are (at least partly) dominant, then female-beneficial/male-harmful mutations will accumulate on the X chromosome, while malebeneficial/female-harmful mutations will be removed from the X. This is because the X chromosome spends two-thirds of its evoluti ...
Models of Selection, Isolation, and Gene Flow in Speciation
Models of Selection, Isolation, and Gene Flow in Speciation

... both diversity of DNA sequences and disparity among them. The mutational processes that generate new sequence diversity include point mutation of single nucleotides, duplication, deletion, or gene conversion. These processes operate on relatively short time scales within lineages of cells and organi ...
Lecture 3 - Montefiore Institute ULg
Lecture 3 - Montefiore Institute ULg

... GBIO0002 - LECTURE 3 ...
Charles K. Wairuri , Jacquie E. van der Waals
Charles K. Wairuri , Jacquie E. van der Waals

... structures that radiate from the bacterial surface and typically consist of only one structural ...
Advances in Environmental Biology (
Advances in Environmental Biology (

... Makoo (36°, 35′S and 48°, 22′E) in West-Azerbaijan province. In general, the flock is managed under a semimigratory system. Ewes are raised in an annual breeding cycle starting in August. There is one breeding season in August-October. Ewes in heat are exposed to pre-defined rams at morning. Lambing ...
SNP Set Analysis for Detecting Disease Association Using Exon
SNP Set Analysis for Detecting Disease Association Using Exon

... individuals are fixed to be 209 and 488, respectively, which reflects the population prevalence of this disease. The 697 individuals were from seven different sources: Denver-Chinese, Han-Chinese, Japanese, Luhya, Yoruba, CEPH, and Tuscan. Through principal component analysis on about 1000 common va ...
Introduction - Stellenbosch University
Introduction - Stellenbosch University

How were introns inserted into nuclear genes?
How were introns inserted into nuclear genes?

... proteases and calcium-binding proteins have apparentinserted by a mechanism that no longer exists in the ly been inserted into highly conserved coding regions, limited range of phyla 'that have been studied within which certain nucleotides must always have although more extensive study of Protista, ...
Gene families and evolution of trehalose
Gene families and evolution of trehalose

... Phylogenetic analysis of the A. thaliana TPS genes showed that they cluster into two distinct subfamilies, designated class I (AtTPS1–4) and class II (AtTPS5–11) (Leyman et al. 2001). All of the proteins encoded by these genes contain a glucosyltransferase-like domain similar to the TPS enzymes from ...
Multifractal analysis of DNA sequences using a novel chaos
Multifractal analysis of DNA sequences using a novel chaos

... the decay of correlations in the DNA sequence by Gxing a scale k = 1=2L , that corresponds to subsequences of length L, and by computing directly the spectrum fL () at that scale using (6). The way in which the spectrum varies provides a quantiGcation of the non-random structures existing within th ...
Genetically Essential and Nonessential a-Tubulin Genes Specify Functionally Interchangeable Proteins.
Genetically Essential and Nonessential a-Tubulin Genes Specify Functionally Interchangeable Proteins.

... be favored greatly by cutting the plasmid with a restriction enzyme in the sequences homologous to that locus (26). The second method, reported by Rothstein (33), can be used to create a simultaneous insertion and deletion in the gene of interest. An internal fragment of the gene is removed and repl ...
Application of the new manP counter-selection system for B. subtilis
Application of the new manP counter-selection system for B. subtilis

... In order to develop a new efficient counter-selection system for B. subtilis, we took ...
THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL

... Lectures 11 &12-Virology and Bacterial Viruses – Chapters 8 & 9 You should be able to: 1. define a virus 2. describe different types of viruses 3. explain how to count virus particles 4. describe and explain the steps in viral growth 5. work problems in viral genetics 6. describe lytic and lysogeni ...
Practice exam
Practice exam

... This is a closed book, closed notes exam. Please confine your answers to the space provided. ...
Horner VL, Caspary T. Methods Mol Biol. 2011;770:313-36. Creating a hopeful monster: mouse forward genetic screens.
Horner VL, Caspary T. Methods Mol Biol. 2011;770:313-36. Creating a hopeful monster: mouse forward genetic screens.

... 1. Mice: 7- to 8-week-old males of the desired strain for mutagenization (Section 3.2). 2. N-ethyl-N-nitrosourea (ENU). ...
PDF version - GeneNetwork
PDF version - GeneNetwork

... forerunner and experimental companion of personalized health genomics and precision medicine. Thanks to recent breakthroughs in sequencing technology, GN can now also be used for novel reverse genetics approaches such as phenome-wide association studies (PheWAS). In a typical reverse genetics approa ...
CpG Mutation Rates in the Human Genome Are
CpG Mutation Rates in the Human Genome Are

... shown that DNA melting is the rate-limiting step in cytosine deamination. Here we show, through the analysis of human single-nucleotide polymorphisms (SNPs), that the mutation rate produced by 5mC deamination is highly dependent on local GC content. In fact, linear regression analysis showed that th ...
Model information sheet - EU
Model information sheet - EU

... Therefore the 129/OlaHsd strain is renamed into 129P2/OlaHsd and 129/SvHsd is renamed into 129S2/ SvHsd. The choice of a particular substrain may be of critical importance for a particular project. ...
The Effect of OmpA Expression on Hfr Conjugation Efficiency
The Effect of OmpA Expression on Hfr Conjugation Efficiency

A Large Pseudoautosomal Region on the Sex Chromosomes of the
A Large Pseudoautosomal Region on the Sex Chromosomes of the

... Charlesworth D 2000). Suppressed recombination between sex chromosomes thus has important implications for genome evolution, speciation, and adaptation. Sex chromosome “degeneration” can be associated with sex chromosome divergence resulting from suppressed recombination and involves the loss of cod ...
gene (Pun1? - UC Davis Plant Sciences
gene (Pun1? - UC Davis Plant Sciences

... All the above provide evidence that Pun1 encodes an acyltransferase involved in capsaicinoid biosynthesis (is it the capsaicin synthase?) ...
Development and implementation of genomic predictions in beef cattle
Development and implementation of genomic predictions in beef cattle

... reduced-density panels by Zoetis or GeneSeek, the respective genotypes being imputed to 54,000 SNPs with a single prediction equation used to generate the molecular breeding value (MBV), which can subsequently be included in national genetic evaluation as a single correlated trait for each reported ...
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Pathogenomics

Pathogen infections are among the leading causes of infirmity and mortality among humans and other animals in the world. Until recently, it has been difficult to compile information to understand the generation of pathogen virulence factors as well as pathogen behaviour in a host environment. The study of Pathogenomics attempts to utilize genomic and metagenomics data gathered from high through-put technologies (e.g. sequencing or DNA microarrays), to understand microbe diversity and interaction as well as host-microbe interactions involved in disease states. The bulk of pathogenomics research concerns itself with pathogens that affect human health; however, studies also exist for plant and animal infecting microbes.
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