Finding Patterns in Protein Sequence and Structure
... phylogeny of the species. The distance-based phylogeny was constructed using the fraction of genes shared between genomes as a similarity criterion29. The major kingdoms of life are indicated in red (Archaea), blue (Bacteria) and yellow (Eukarya). Question marks represent reactions for which there i ...
... phylogeny of the species. The distance-based phylogeny was constructed using the fraction of genes shared between genomes as a similarity criterion29. The major kingdoms of life are indicated in red (Archaea), blue (Bacteria) and yellow (Eukarya). Question marks represent reactions for which there i ...
46556-2-12118
... The parallel measurement of the concentration, or expression, of RNA molecules for thousands of genes enables a large-scale unbiased profiling of a heritable cellular trait that mediates the genetic basis of complex phenotypes. The resulting data forms a highdimensional multivariate sample which, to ...
... The parallel measurement of the concentration, or expression, of RNA molecules for thousands of genes enables a large-scale unbiased profiling of a heritable cellular trait that mediates the genetic basis of complex phenotypes. The resulting data forms a highdimensional multivariate sample which, to ...
On bioinformatics
... obtained from the Protein Data Bank (PDB); Cn3D (a 3D-structure viewer); vector alignment search tool (VAST), and other protein structure resources ...
... obtained from the Protein Data Bank (PDB); Cn3D (a 3D-structure viewer); vector alignment search tool (VAST), and other protein structure resources ...
Lecture_4
... conserved domains rather than full-length proteins • TIGRfam - strives to find equivalogs - “proteins that are conserved with respect to FUNCTION since their last common ancestor” ...
... conserved domains rather than full-length proteins • TIGRfam - strives to find equivalogs - “proteins that are conserved with respect to FUNCTION since their last common ancestor” ...
20.1 Structural Genomics Determines the DNA Sequences of Entire
... • Whole-genome shotgun sequencing: Small-insert clones are prepared directly from genomic DNA and sequenced in a highly automated way. ...
... • Whole-genome shotgun sequencing: Small-insert clones are prepared directly from genomic DNA and sequenced in a highly automated way. ...
CRACKING THE CODE OF LIFE QUESTIONS
... 9. Why doesn’t work get done on certain regions of DNA molecules? 10. Are genes one-dimensional or 3-dimensional? 11. What do genes do – basically? 12. What was every week like at Solaris? 13. How many of the 17 children have arthritis? 14. What are the “guys in the funny suits” making? 15. BRCA mut ...
... 9. Why doesn’t work get done on certain regions of DNA molecules? 10. Are genes one-dimensional or 3-dimensional? 11. What do genes do – basically? 12. What was every week like at Solaris? 13. How many of the 17 children have arthritis? 14. What are the “guys in the funny suits” making? 15. BRCA mut ...
Supplementary data
... and Porphyromonas gingivalis ATCC33277, Actinomyces odontolyticus ATCC 17982 [7,8]. Remarkably, when the genome sequence of B. dentium Bd1 was compared to a genome database representing these oral pathogenic strains mentioned above (oral pathogen pangenome), a large number (around 1390) of significa ...
... and Porphyromonas gingivalis ATCC33277, Actinomyces odontolyticus ATCC 17982 [7,8]. Remarkably, when the genome sequence of B. dentium Bd1 was compared to a genome database representing these oral pathogenic strains mentioned above (oral pathogen pangenome), a large number (around 1390) of significa ...
Gen660_Week4a_HGT_2014
... genes in E. coli (but not all species … why?) Mobile elements more prominent for some species Some species more readily take up DNA; others do not do homologous recombination well Some species occupy very narrow niche – little exposure to other DNA, etc From Mira et al. 2010. Internat. Micro ...
... genes in E. coli (but not all species … why?) Mobile elements more prominent for some species Some species more readily take up DNA; others do not do homologous recombination well Some species occupy very narrow niche – little exposure to other DNA, etc From Mira et al. 2010. Internat. Micro ...
Study Guide
... is all of an organism’s proteins. What does this information tell you about genomics, proteomics, and bioinformatics? ...
... is all of an organism’s proteins. What does this information tell you about genomics, proteomics, and bioinformatics? ...
Simple tandem repeats in mammalian genomes
... The sequencing of the human genome lead to some surprises concerning the number of genes. The number of human genes seems to be around 30,000, much less than expected. This number is not a lot higher than the number of genes of “lower” organisms, like the worm Caenorhabditis elegans with its more th ...
... The sequencing of the human genome lead to some surprises concerning the number of genes. The number of human genes seems to be around 30,000, much less than expected. This number is not a lot higher than the number of genes of “lower” organisms, like the worm Caenorhabditis elegans with its more th ...
A genome is the full set of genetic information that an organism
... 10. To analyze the pattern of inheritance followed by a particular trait, you can use a chart that shows the relationships within a family. Such a chart is called a pedigree. 11. The information gained from pedigree analysis makes it possible to determine the nature of genes and alleles associated w ...
... 10. To analyze the pattern of inheritance followed by a particular trait, you can use a chart that shows the relationships within a family. Such a chart is called a pedigree. 11. The information gained from pedigree analysis makes it possible to determine the nature of genes and alleles associated w ...
Answers to Biological Inquiry Questions – Brooker et al ARIS site
... BIOLOGICAL INQUIRY QUESTION: What are two reasons why the groups of species shown in (a) have variation in their total amount of DNA? ANSWER: One reason is that more complex species tend to have more genes. A second reason is that species vary with regard to the amount of repetitive DNA that is foun ...
... BIOLOGICAL INQUIRY QUESTION: What are two reasons why the groups of species shown in (a) have variation in their total amount of DNA? ANSWER: One reason is that more complex species tend to have more genes. A second reason is that species vary with regard to the amount of repetitive DNA that is foun ...
Overture
... – One good reason: structure gives clues about function. If we can tell the structure, we can perhaps tell the function – We can design amino acid sequences that will fold into proteins that do what we want them to do. Drug design !! ...
... – One good reason: structure gives clues about function. If we can tell the structure, we can perhaps tell the function – We can design amino acid sequences that will fold into proteins that do what we want them to do. Drug design !! ...
Pathogens and Disease
... 1. You didn’t take the antibiotics long enough to kill all of the bacteria 2. All partly resistant bacteria had the chance to reproduce and possibly become more ...
... 1. You didn’t take the antibiotics long enough to kill all of the bacteria 2. All partly resistant bacteria had the chance to reproduce and possibly become more ...
TALK
... amount of DNA which serves no useful function for the cell. Introns, inteins, transposons and pesudogenes are examples of "selfish DNA", which persist because their impact on cellular replication efficiency is too small for selection to act directly. This DNA may be eliminated by chance due to a gen ...
... amount of DNA which serves no useful function for the cell. Introns, inteins, transposons and pesudogenes are examples of "selfish DNA", which persist because their impact on cellular replication efficiency is too small for selection to act directly. This DNA may be eliminated by chance due to a gen ...
Gene and Gene Regulation
... A section of DNA that synthesizes a protein that is needed for traits ...
... A section of DNA that synthesizes a protein that is needed for traits ...
Slide 1
... Figure 1 Genes used to study RNA-mediated genetic interference in C.elegans. Intron–exon structure for genes used to test RNA-mediated inhibition are shown (grey and filled boxes, exons; open boxes, introns; patterned and striped boxes, 5' and 3' untranslated regions. unc-22. ref. 9, unc-54, ref. 1 ...
... Figure 1 Genes used to study RNA-mediated genetic interference in C.elegans. Intron–exon structure for genes used to test RNA-mediated inhibition are shown (grey and filled boxes, exons; open boxes, introns; patterned and striped boxes, 5' and 3' untranslated regions. unc-22. ref. 9, unc-54, ref. 1 ...
Future Directions Project Objectives Why Sequence Ferns?
... significance of polyploidy in the Pteridophyta. Science 153: 305-307; 4Novak P et al. 2013. RepeatExplorer: A Galaxy-based web server for genome-wide characterization of eukaryotic repetitive elements from next generation sequence reads. Bioinformatics ...
... significance of polyploidy in the Pteridophyta. Science 153: 305-307; 4Novak P et al. 2013. RepeatExplorer: A Galaxy-based web server for genome-wide characterization of eukaryotic repetitive elements from next generation sequence reads. Bioinformatics ...
