Genetica per Scienze Naturali aa 05
... The globin gene family provides a particularly good example of how DNA duplication generates new proteins, because its evolutionary history has been worked out particularly well. We can reconstruct some of the past events that produced the various types of oxygen-carrying hemoglobin molecules by con ...
... The globin gene family provides a particularly good example of how DNA duplication generates new proteins, because its evolutionary history has been worked out particularly well. We can reconstruct some of the past events that produced the various types of oxygen-carrying hemoglobin molecules by con ...
Dosage sensitivity and the evolution of gene families in yeast
... expression patterns across time for each gene pair (resulting in 454 pairs; see Methods). In agreement with expectations, the frequency of co-expressed gene pairs sharply falls with increasing mean heterozygote fitness (Fig. 2). In particular, only 20% of the interacting pairs with less than 5% fitn ...
... expression patterns across time for each gene pair (resulting in 454 pairs; see Methods). In agreement with expectations, the frequency of co-expressed gene pairs sharply falls with increasing mean heterozygote fitness (Fig. 2). In particular, only 20% of the interacting pairs with less than 5% fitn ...
Genome-Wide Prediction of Functional Gene
... words, in a large set of RILs we might observe significant Linkage Disequilibrium (LD) between physically unlinked genes if these genes jointly affect an adaptive phenotype [5] and some combinations are more likely than others to survive the process of inbreeding. In fact, this idea has been pursued ...
... words, in a large set of RILs we might observe significant Linkage Disequilibrium (LD) between physically unlinked genes if these genes jointly affect an adaptive phenotype [5] and some combinations are more likely than others to survive the process of inbreeding. In fact, this idea has been pursued ...
HSV-1 - Iranian Biomedical Journal
... restriction enzymes is used to differentiate types one and two of the virus and even strains of each type. Previous studies using PCR-sequencing technique have shown that the thymidine kinase (TK) gene of HSV-1 is polymorphic. Methods: In this study, TK gene and DNA binding protein (UL29) gene of HS ...
... restriction enzymes is used to differentiate types one and two of the virus and even strains of each type. Previous studies using PCR-sequencing technique have shown that the thymidine kinase (TK) gene of HSV-1 is polymorphic. Methods: In this study, TK gene and DNA binding protein (UL29) gene of HS ...
The ADAMTS1 Gene Is Associated with Familial Mandibular
... There are several subtypes of MP, such as mandibular overgrowth with or without maxillary retrusion. Since there is extensive clinical heterogeneity, the genetic bases of types of MP may be different (Xue et al. 2010; Li et al. 2011). There are many genes known to be involved in the process of mandi ...
... There are several subtypes of MP, such as mandibular overgrowth with or without maxillary retrusion. Since there is extensive clinical heterogeneity, the genetic bases of types of MP may be different (Xue et al. 2010; Li et al. 2011). There are many genes known to be involved in the process of mandi ...
- CSHL Institutional Repository
... toolkit. GMOD is an open source project initiated in 2002 with the objective of providing generic software so that a small community with limited informatics infrastructure can build a new model organism database. We provide a brief description of the GMOD core components used to build ParameciumDB. ...
... toolkit. GMOD is an open source project initiated in 2002 with the objective of providing generic software so that a small community with limited informatics infrastructure can build a new model organism database. We provide a brief description of the GMOD core components used to build ParameciumDB. ...
Mice, humans and haplotypes—the hunt for disease genes in SLE
... to particular strains. That is they arise from variations that are common in inbred and may originate in wild-type mice. Needless to say, recent human population history differs somewhat from that of inbred laboratory mice. However, what the two species have in common is that ‘recent’ events have ha ...
... to particular strains. That is they arise from variations that are common in inbred and may originate in wild-type mice. Needless to say, recent human population history differs somewhat from that of inbred laboratory mice. However, what the two species have in common is that ‘recent’ events have ha ...
Transcription start sites
... • Twice as many transcription start sites as traditional “genes” • transcripts span large regions, even between genes ...
... • Twice as many transcription start sites as traditional “genes” • transcripts span large regions, even between genes ...
Mendelian Genetics Objectives (Chapter 14)
... during meiosis and fusion of gametes at fertilization are random events Apply the "multiplication" rule to predicting probabilities of specific outcomes from genetic crosses Apply the "addition" rule to predicting probabilities of specific outcomes from genetic crosses Use a Punnett Square to predic ...
... during meiosis and fusion of gametes at fertilization are random events Apply the "multiplication" rule to predicting probabilities of specific outcomes from genetic crosses Apply the "addition" rule to predicting probabilities of specific outcomes from genetic crosses Use a Punnett Square to predic ...
slide presentation
... Plants as trait assemblages A competition matrix has bee computed, wih the hypothesis that - Interacting plants are trait assemblages - competition coefficient aij is calculated knowing the traits in each plant Each trait is binary ...
... Plants as trait assemblages A competition matrix has bee computed, wih the hypothesis that - Interacting plants are trait assemblages - competition coefficient aij is calculated knowing the traits in each plant Each trait is binary ...
2009 Hart and Grosbe.. - Evolution and Ecology | UC Davis
... molecular mechanisms of adaptive phenotypic evolution. An incisive test of Williamson’s specific prediction (6) will depend on the results of a whole-genome sequence analysis of a velvet worm. The best available evidence comes from molecular phylogenetic analyses, which Williamson’s hypothesis predi ...
... molecular mechanisms of adaptive phenotypic evolution. An incisive test of Williamson’s specific prediction (6) will depend on the results of a whole-genome sequence analysis of a velvet worm. The best available evidence comes from molecular phylogenetic analyses, which Williamson’s hypothesis predi ...
Text S1.
... expressed. The score thus serves as a measure that values both magnitude of expression change in response to a condition contrast, as well as coherence of expression within that contrast. The score identifies the most relevant contrasts as those where the genes 'act as one', showing the same, prefer ...
... expressed. The score thus serves as a measure that values both magnitude of expression change in response to a condition contrast, as well as coherence of expression within that contrast. The score identifies the most relevant contrasts as those where the genes 'act as one', showing the same, prefer ...
mendel II
... inversely proportional to their size: small, highly charged molecules move faster than large, less charged molecules. • Electrophoresis is done in a gel matrix, to prevent diffusion from confusing the results. ...
... inversely proportional to their size: small, highly charged molecules move faster than large, less charged molecules. • Electrophoresis is done in a gel matrix, to prevent diffusion from confusing the results. ...
Genome structure and organization
... phenotype Multiple families used in most studies If different families have different gene mutations, power of statistics to detect linkage will drop ...
... phenotype Multiple families used in most studies If different families have different gene mutations, power of statistics to detect linkage will drop ...
Public Microarray Databases
... cancer, name of gene”. We identified 261 genes related to bladder cancer Data was summarized in a list containing gene information and interacting genes. ...
... cancer, name of gene”. We identified 261 genes related to bladder cancer Data was summarized in a list containing gene information and interacting genes. ...
Document
... after the multiple testing correction. If there are no significant genes left after multiple testing correction, you probably have some differences, but not enough power in your experiment to detect those differences. In that case the top 10 genes are still the ones that are most likely to validate. ...
... after the multiple testing correction. If there are no significant genes left after multiple testing correction, you probably have some differences, but not enough power in your experiment to detect those differences. In that case the top 10 genes are still the ones that are most likely to validate. ...
Identifying differentially expressed sets of genes in microarray
... genes associated with a particular location in the cell, or genes having a particular function or being involved in a particular process. We could even include sets of genes for which all of the preceding are unknown, but we have reason believe could be of interest, typically from previous experimen ...
... genes associated with a particular location in the cell, or genes having a particular function or being involved in a particular process. We could even include sets of genes for which all of the preceding are unknown, but we have reason believe could be of interest, typically from previous experimen ...
4_Diff_Analysis_and_Samp_Features_Mar2011
... – If number of significant hypotheses/genes “too large” even for very small threshold values, either: • use the maxT correction (possible w/ empirical p-values only). • use additional criteria (e.g., min fold-change, min expression value, etc.) ...
... – If number of significant hypotheses/genes “too large” even for very small threshold values, either: • use the maxT correction (possible w/ empirical p-values only). • use additional criteria (e.g., min fold-change, min expression value, etc.) ...
Speciation Genes (How does one species become two?)
... D. simulans X D. mauritiana = male sterility, females ok Odysseus (OdsH): rapidly evolving homeobox gene, evolving away from ...
... D. simulans X D. mauritiana = male sterility, females ok Odysseus (OdsH): rapidly evolving homeobox gene, evolving away from ...
Exceptions to Mendel`s Principles
... Eye color in fruit flies – 3 genes Skin color in humans – there are three or four genes involved in the inheritance of skin color in humans ...
... Eye color in fruit flies – 3 genes Skin color in humans – there are three or four genes involved in the inheritance of skin color in humans ...
Seeking Out Dislipidemia Variants with LipidSeq
... locally realigned, have PCR duplicates removed, and then have variants called to produce 24 VCF files. The VCF files are annotated so that we can then identify familiar and novel variants that can be attributed to causing the phenotype. Q: Can you identify polygenic as well as monogenic variants? JR ...
... locally realigned, have PCR duplicates removed, and then have variants called to produce 24 VCF files. The VCF files are annotated so that we can then identify familiar and novel variants that can be attributed to causing the phenotype. Q: Can you identify polygenic as well as monogenic variants? JR ...
Promoter Analysis for Intestinally
... a. The sequences of all hits were extracted and flipped to the strand that maximized As and Gs. b. The sequences were then run through ClustalW. Alignments can be seen in the following file: i. C. elegans : Cele_all_hits_aligned.txt ii. C. briggsae: Cbri_all_hits_aligned.txt iii. C. remanei : Crem_a ...
... a. The sequences of all hits were extracted and flipped to the strand that maximized As and Gs. b. The sequences were then run through ClustalW. Alignments can be seen in the following file: i. C. elegans : Cele_all_hits_aligned.txt ii. C. briggsae: Cbri_all_hits_aligned.txt iii. C. remanei : Crem_a ...