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Host-induced epidemic spread of the cholera bacterium
Host-induced epidemic spread of the cholera bacterium

... Testing of the human shed V.cholerae occurred in order to test if the hyperinfectious phenotype was maintatined. • V.cholerae samples that were freshly shed were diluted in pond water that was free from contaminants of V.cholerae • Incubation at room temperature for 5 hrs, then diluted samples were ...
Results - Hal Cirad
Results - Hal Cirad

... resulted from a natural hybridization between two wild diploids Coffea species (Carvalho, 1952). Polyploids are common in certain plant and animal taxa, and the genetic and evolutionary consequences of genome duplication have been recently reviewed (Comai, 2005). In particular for allotetrapolyploid ...
Automatic detection of conserved gene clusters in
Automatic detection of conserved gene clusters in

... Generally speaking there are two representative clustering algorithms: single linkage and complete linkage. When single linkage is applied to our problem, many gene clusters tend to be merged into a small number of large groups. In the worst case, two unrelated clusters may be merged in the same gro ...
Chapter 29 DNA as the Genetic Material Recombination of DNA
Chapter 29 DNA as the Genetic Material Recombination of DNA

... • Messelson and Weigle showed by 13 C and 15N labeling that recombinant phage contained DNA from both “parents” ...
Gene Rearrangement Analysis and Ancestral Order Inference from
Gene Rearrangement Analysis and Ancestral Order Inference from

... changes but also events that alter the chromosome structure, such as inversions, duplications or deletions [1]. Ancestral gene sequence inference has led to significant predictions of protein functional shift and positive selection [2]. For example, comparisons of orthologous chromosomal segments sh ...
rearrangements
rearrangements

... are next to each other and arranged head to tail relative to one another. ...
Response to Nelson-Sathi et al. (Nature 517, 77-80
Response to Nelson-Sathi et al. (Nature 517, 77-80

... the results with a gain cost of 2 and 4, from left to right respectively. In ML, ancestral branch-specific gain expectations were computed from rates of gene gain and loss estimated either from the 2,264, 3,315 or 25,762 gene family sets defined by NS, from left to right respectively. All analyses a ...
Information Encoding in Biological Molecules: DNA and
Information Encoding in Biological Molecules: DNA and

... Stephen Baird Apoptosis Research Centre Children’s Hospital of Eastern Ontario [email protected] ...
Duplication
Duplication

Large-Scale Variation Among Human and Great Ape Genomes
Large-Scale Variation Among Human and Great Ape Genomes

... comparative genomic hybridization (array CGH), measuring copy-number gains and losses among these species. Using an array of 2460 human bacterial artificial chromosomes (BACs) (12% of the genome), we identified a total of 63 sites of putative DNA copy-number variation between humans and the great ap ...
Chi-Square Analysis
Chi-Square Analysis

... (when does this occur during meiosis?)  If offspring look like parents  parental types  If different from parents  recombinants ...
Part 1 Microarray Timeseries Analysis with
Part 1 Microarray Timeseries Analysis with

... Current methods for classifying human malignancies rely on a variety of morphological, clinical, and molecular variables. In spite of recent progress, there are still uncertainties in diagnosis. Also, it is likely that the existing classes are heterogeneous. DNA microarrays may be used to characteri ...
Autosomal Non-Mendelian Inheritance
Autosomal Non-Mendelian Inheritance

... taken up by the hydrangea, and ultimately bind to a pigment found in the vacuoles of the flower cells. This binding causes a conformational change in the pigment, changing the wavelengths of light it reflects and making the flowers appear a different color. In the case of the snowshoe hair, the phen ...
ppt - Chair of Computational Biology
ppt - Chair of Computational Biology

... Forward genetics Instead one often uses forward genetic (also called classical genetic) approach to discover the function(s) of a gene Its allows - to consider gain-of function mutations, - identifying genes acting within a common pathway as well as genes encoding for interacting proteins and - it ...
Evolution of hominoids and the search for a genetic basis for
Evolution of hominoids and the search for a genetic basis for

L11_SUMMARY_DE
L11_SUMMARY_DE

... • We are not in principle comparing different genes, but rather the same genes across different groups, and in most experiments, few genes change more than three-fold in mean levels. • For studies where gene levels are fairly constant, and changes are expected to be modest, such as neuroscience stud ...
Human fertility gene found - Carole Ober
Human fertility gene found - Carole Ober

... Many genes have been identified that cause infertility in humans, but finding genes that enhance fertility is tougher because people often choose to limit their family size for various cultural, social, and economic reasons. The Hutterites, however, do the opposite. This isolated group of Anabaptist ...
Establishment of a screening service for BM and UCMD
Establishment of a screening service for BM and UCMD

Document
Document

... from a single gene multiple transcripts) AS is tissue-specific (Graveley, 2001) AS is related to human diseases ...
Genomewide Association Studies and Human Disease
Genomewide Association Studies and Human Disease

... they present formidable logistical and technical challenges. The primary challenge lies in selecting a disease or a trait suitable for analysis. A successful analysis is more likely when the phenotype of interest can be sensitively and specifically diagnosed or measured. For such studies, extremely ...
One vitellogenin gene in an ocean of many: The molecular ecology
One vitellogenin gene in an ocean of many: The molecular ecology

... the branching topology was highly congruent with speciation events, which due to the broad sampling strategy, could be discerned at the levels of clade and order. The most widely sampled forms of aquaglyceroporin were aqp3, -7, -9 and -10, with aqp3 on a sister branch to aqp9, and aqp7 clustering wi ...
Phenotype Sequencing - Bioinformatics Research Group
Phenotype Sequencing - Bioinformatics Research Group

... Starting with a parent organism, create many mutants using random mutagenesis (e.g. UV, NTG) ...
NOTE Phylogenetic analysis of Gram
NOTE Phylogenetic analysis of Gram

... 1997). It is probable that the dnaK and\or dnaJ homologues in some of the bacterial genera were acquired through horizontal transfer followed by loss of the ancestral copy in some organisms. On the other hand, the presence of a single grpE gene across bacterial genera represents ancestral gene copy ...
Quantitative genetics
Quantitative genetics

... • G - Genetic factors, E - environmental factors, GxE interactions, A - additive effects, D – dominance (alleles at one locus), E – epistasis (alles at different loci), C common and E - non-shared environment (children in one family are different) • EEE... ...
10.2 AHL Dihybrid Cross and Linked Genes
10.2 AHL Dihybrid Cross and Linked Genes

... In garden peas, the pairs of alleles coding for seed shape and seed colour are unlinked. The allele for smooth seeds (S) is dominant over the allele for wrinkled seeds (s). The allele for yellow seeds (Y) is dominant over the allele for green seeds (y). If a plant of genotype Ssyy is crossed with a ...
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Pathogenomics

Pathogen infections are among the leading causes of infirmity and mortality among humans and other animals in the world. Until recently, it has been difficult to compile information to understand the generation of pathogen virulence factors as well as pathogen behaviour in a host environment. The study of Pathogenomics attempts to utilize genomic and metagenomics data gathered from high through-put technologies (e.g. sequencing or DNA microarrays), to understand microbe diversity and interaction as well as host-microbe interactions involved in disease states. The bulk of pathogenomics research concerns itself with pathogens that affect human health; however, studies also exist for plant and animal infecting microbes.
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