... contributing to adiposity and obesity. We have developed methods for high-resolution in vivo imaging of zebrafish adipose tissues, and used them to reveal that zebrafish and mammalian adipose tissues share extensive physiological, morphological, and molecular homologies. We also show that these meth ...
Part 1 Microarray Timeseries Analysis with replicates OSM
... 1. Permute the n data points for the gene (x). The first n1 are referred to as “treatments”, the second n2 as “controls”. 2. For each gene, calculate the corresponding two sample t-statistic, tb. After all the B permutations are done: ...
... 1. Permute the n data points for the gene (x). The first n1 are referred to as “treatments”, the second n2 as “controls”. 2. For each gene, calculate the corresponding two sample t-statistic, tb. After all the B permutations are done: ...
Reverse Genetics- Gene Knockouts
... the double stranded RNA turns off the respective gene in C. elegans. 16,757 genes have been expressed, representing 87% of the genome. Since RNAi reduces but does not eliminate expression of a gene, consortiums are currently creating small deletions using treatment of worms with 4,5',8-trimethylpso ...
... the double stranded RNA turns off the respective gene in C. elegans. 16,757 genes have been expressed, representing 87% of the genome. Since RNAi reduces but does not eliminate expression of a gene, consortiums are currently creating small deletions using treatment of worms with 4,5',8-trimethylpso ...
Gene Net Analysis: Motifs vs. Correlation
... individual genes. In addition, we can include random variables that denote other attributes that affect the system (experimental conditions, temporal indicators…). We want to learn one from the available data and use it to answer questions about the system. ...
... individual genes. In addition, we can include random variables that denote other attributes that affect the system (experimental conditions, temporal indicators…). We want to learn one from the available data and use it to answer questions about the system. ...
Making Sense of Complicated Microarray Data
... • Unordered discrete scales: multiple types of treatment or mutations, tissue types etc • Continuous scales: time courses, levels of treatment, etc ...
... • Unordered discrete scales: multiple types of treatment or mutations, tissue types etc • Continuous scales: time courses, levels of treatment, etc ...
Phylogenetics Topic 2: Phylogenetic and genealogical homology
... A general model for evolutionary dissociation might involve GENETIC CO-OPTION; here existing genetic systems are modified, or co-opted, for new uses. In evolutionary terms this is much more efficient than having to construct a system from scratch to provide a new or modified function. The process o ...
... A general model for evolutionary dissociation might involve GENETIC CO-OPTION; here existing genetic systems are modified, or co-opted, for new uses. In evolutionary terms this is much more efficient than having to construct a system from scratch to provide a new or modified function. The process o ...
Microviridae goes temperate: microvirus-related - HAL
... genus Microvirus, whereas those infecting obligate parasitic bacteria, such as Chlamydia, Spiroplasma and Bdellovibrio, are classified into a subfamily, the Gokushovirinae. Recent metagenomic studies suggest that members of the Microviridae might also play an important role in marine environments. I ...
... genus Microvirus, whereas those infecting obligate parasitic bacteria, such as Chlamydia, Spiroplasma and Bdellovibrio, are classified into a subfamily, the Gokushovirinae. Recent metagenomic studies suggest that members of the Microviridae might also play an important role in marine environments. I ...
Structure, Expression and Duplication of Genes Which Encode
... Suurvm et al. 1985). This study details the molecular characterization of an additional member of this set of genes, the gene that encodes phosphoglyceromutase (PGLYM). PGLYM catalyzes the interconversion of 2-phosphoglycerate and %phosphoglycerate. PGLYM from insects has not been well characterized ...
... Suurvm et al. 1985). This study details the molecular characterization of an additional member of this set of genes, the gene that encodes phosphoglyceromutase (PGLYM). PGLYM catalyzes the interconversion of 2-phosphoglycerate and %phosphoglycerate. PGLYM from insects has not been well characterized ...
The Graph of Life
... •Horizontal gene transfer, e.g. bacterial orgy •Convergent evolution (think cactus, only at genomic level) ...
... •Horizontal gene transfer, e.g. bacterial orgy •Convergent evolution (think cactus, only at genomic level) ...
Arabidopsis thaliana Arabidopsis thaliana
... Unlike animals, which use a sodium ion P-type ATPase pump to generate an electrochemical gradient across the plasma membrane, plants and fungi use a proton Ptype ATPase pump to form a large membrane potential. plant secondary transporters are typically coupled to protons rather than to sodium. -alm ...
... Unlike animals, which use a sodium ion P-type ATPase pump to generate an electrochemical gradient across the plasma membrane, plants and fungi use a proton Ptype ATPase pump to form a large membrane potential. plant secondary transporters are typically coupled to protons rather than to sodium. -alm ...
Human and murine PTX1/Ptx1 gene maps to the region for Treacher
... PTX1, like its murine and chick homologs, possesses a homeodomain with a bicoid-class third helix. The homeodomain is highly conserved between mouse and human (100%), as are the Cand N- termini (88 and 97% respectively; Fig. 3a,b). This conservation is also evident at the level of gene structure as ...
... PTX1, like its murine and chick homologs, possesses a homeodomain with a bicoid-class third helix. The homeodomain is highly conserved between mouse and human (100%), as are the Cand N- termini (88 and 97% respectively; Fig. 3a,b). This conservation is also evident at the level of gene structure as ...
PowerPoint プレゼンテーション
... on the right are the pre-calculated databases that supply the design algorithm with genomic or sequence information, enabling fast and efficient information management during the design procedure. The main part of E-TALEN consists of design algorithms that find and validate putative TALEN targets, f ...
... on the right are the pre-calculated databases that supply the design algorithm with genomic or sequence information, enabling fast and efficient information management during the design procedure. The main part of E-TALEN consists of design algorithms that find and validate putative TALEN targets, f ...
click here
... 4. “An inherited state that is determined by segregating alleles of many different genes, whose interactions (environmental/ genetic)...produce a phenotype exhibiting many intermediate forms... This is a strict definition of a continuous or quantitative trait; see pages 68-70 (end of chapter 3). Ans ...
... 4. “An inherited state that is determined by segregating alleles of many different genes, whose interactions (environmental/ genetic)...produce a phenotype exhibiting many intermediate forms... This is a strict definition of a continuous or quantitative trait; see pages 68-70 (end of chapter 3). Ans ...
ppt - Department of Plant Sciences
... Example: EcoRI • What is the probability of a sequence of DNA in a plant genome having the sequence of bases corresponding to an EcoRI cut site? • Each site can be 4 possible bases (A, T, C, or G), and the EcoRI enzyme requires 6 sites (GAATTC) • The probability of finding a random site in a genome ...
... Example: EcoRI • What is the probability of a sequence of DNA in a plant genome having the sequence of bases corresponding to an EcoRI cut site? • Each site can be 4 possible bases (A, T, C, or G), and the EcoRI enzyme requires 6 sites (GAATTC) • The probability of finding a random site in a genome ...
ppt for
... Rare and common genetic risk variants are significantly enriched in specific neuronal modules • 246 autism susceptibility genes was compiled using the SFARI gene database (https://sfari.org/sfari-gene), and was restricted to the 121 genes with reported rare mutations in autism. • 91% (109 genes) we ...
... Rare and common genetic risk variants are significantly enriched in specific neuronal modules • 246 autism susceptibility genes was compiled using the SFARI gene database (https://sfari.org/sfari-gene), and was restricted to the 121 genes with reported rare mutations in autism. • 91% (109 genes) we ...
TGAC * Sequence Polymorphisms Module
... Inheritance in Man. A database that contains all known loci in the human genome that have been found associated with human phenotypes, including diseases and disorders. ...
... Inheritance in Man. A database that contains all known loci in the human genome that have been found associated with human phenotypes, including diseases and disorders. ...
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... own lab, to produce a map of the genetic relatedness of all life. This grand objective was taken up by many labs, and the project quickly gathered momentum. ...
... own lab, to produce a map of the genetic relatedness of all life. This grand objective was taken up by many labs, and the project quickly gathered momentum. ...
Anthropology 7 Problem Set #2
... This series of problems will help you prepare for the examinations, by making certain principles that are important for the course clear. Problem sets are to be turned in to your teaching fellow, and are graded on a satisfactory / unsatisfactory basis. In general, the questions are designed to be ea ...
... This series of problems will help you prepare for the examinations, by making certain principles that are important for the course clear. Problem sets are to be turned in to your teaching fellow, and are graded on a satisfactory / unsatisfactory basis. In general, the questions are designed to be ea ...
