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Metabolic functions of duplicate genes in Saccharomyces cerevisiae
Metabolic functions of duplicate genes in Saccharomyces cerevisiae

... – In several cases, a single major isoform is essential. – Finally, only 19 of all duplicate families (105) are categorized to exhibit a potential dosage function. ...
Finding the wheat homologues of genes from model organisms
Finding the wheat homologues of genes from model organisms

... be associated with the gene tree. Note that the list presented in the orthologue view is extracted from the gene tree data. Follow the steps below to find to use the orthologue feature of Ensembl. 1. Click on the “Orthologue” link under the Plant Compara tool of the gene-based display. This will pre ...
1754-6834-4-30-S5
1754-6834-4-30-S5

... of the supernatant were subsequently pipetted along with 100 μl DNS solution into a clean 96-well PCR plate, sealed, heated at 99°C for five min and cooled at 4°C for one min. Absorbance values at 540 nm were read on an X-mark™ (Biorad, Hercules, CA, USA) or on a Varioscan (Thermo Labsystems) microt ...
Figure 2-1
Figure 2-1

... who later cashed in on using cartilage pills as “natural remedy”. By the way, in my experience sharks do get tumorous growths in their reproductive tract; I did not characterize them to be sure they were a “cancer.” I think you may want to shelve these statements. Some antiangiogenic compounds have ...
Synthetic Biology: ENGINEERING LIFE
Synthetic Biology: ENGINEERING LIFE

... Venter says this is just one of several patent applications that would give his company, Synthetic Genomics Inc., exclusive rights to methods for making synthetic organisms. The artificial Mycoplasma "may or may not be" the one used to generate hydrogen or ethanol, he says; his team is working on se ...
T. caerulescens
T. caerulescens

... • Zinc has been one of the most importaant nutrients in plant growth – Too much zinc can be toxic to plants – Too little zinc can inhibit optimal growth fo plants ...
Identification of large-scale human-specific copy number
Identification of large-scale human-specific copy number

... Number of changes detected by aCGH in primate genomes For each of the primate species investigated (PTR, PPA, GGO, PPY and MFA), DNA from ten unrelated females was pooled, labeled and hybridized together with the differently labeled human reference DNA pool, also consisting of ten unrelated (female) ...
Limitations of Pseudogenes in Identifying Gene Losses
Limitations of Pseudogenes in Identifying Gene Losses

... Query genes that do not hit the D. melanogaster genome. The 114 query genes not hitting the v4.3 D. melanogaster genome were first checked against the v5.3 genome assembly and annotation to determine if any of these potential gene losses are simply due to gaps in the v4.3 assembly. The 114 query sequ ...
An Investigation of Codon Usage Bias Including
An Investigation of Codon Usage Bias Including

... sometimes code for the same amino acid (degeneracy). It has long been known that organisms preferentially utilize one or more of these synonymous codons in their coding sequences [6, 7, 9, 15]. This bias in codon usage can be exploited to predict such things as how often a gene is expressed [5] or w ...
4132010
4132010

... dsRNA hypothesis explained this phenomenon Andrew J. Hamilton and David C. Baulcombe Science 1999 286: 950-52 ...
Analysis of mutant strains
Analysis of mutant strains

Journal of Advanced Computing (2012) 1
Journal of Advanced Computing (2012) 1

The UCSC Genome Browser
The UCSC Genome Browser

... Now you can use your hmm to search for homologs in PDB. Select “Upload a file” and use the HMM that you created, make sure that you select PDB as database. Run HMMsearch and see if you can find any related structures. Did you find any similar structures that you could use for homology modelling? Ano ...
GroEL buffers against deleterious mutations
GroEL buffers against deleterious mutations

... explanation could be that an overproduction of GroEL of about 8616-fold is deleterious because it diverts amino acids away from other cellular functions. To test this, we grew each groE c strain and its ancestor in DM25 supplemented with increasing concentrations of tryptone (a mixture of peptides ...
HapMap PROJECT - Faculty of Science at Bilkent University
HapMap PROJECT - Faculty of Science at Bilkent University

... analysis of coding SNPs. • SNPEffect-estimate likelihood that a particular SNP is causing a functional effect. • SNPSeek->90 000 coding SNPs in the exons of known genes • SNP500Cancer – identification, validation, and characterization of polymorphisms. ...
PDF
PDF

... are expressed. Co-transcription of MIRNAs is not unique to MIR156b/c. For example, 24 MIR395 genes are organized into four compact clusters, each transcribed as a single transcript in rice [17]. Co-transcription of similar or identical MIRNA genes might have a dosage effect in plants. In contrast, an ...
Ensembl Genome Browser - molecularevolution.org
Ensembl Genome Browser - molecularevolution.org

TimeClust: a clustering tool for gene expression
TimeClust: a clustering tool for gene expression

Features on Nucleic Acid Sequences, Gene Features and Coding
Features on Nucleic Acid Sequences, Gene Features and Coding

... to sequences via locations requires the use of more than one table. Simple examples include a promoter, or a repeat region, or a UTR on an NA Sequence. In each case, there is a sequence, there is a feature located on that sequence, and there is a span on that sequence where the feature is located. E ...
We conducted a full analysis on the excluded 26 cases (see details
We conducted a full analysis on the excluded 26 cases (see details

... in D. grimshawi, GH14404 appears to be a best-to-best ortholog of CG13762 based on UCSC genomic alignment. GH14404 is in the Muller D element. Thus case is more likely to be a one-exon-to-multiple-exon DNA-level D-A relocation event. 6) CG14077 This case is similar to CG7557. The major-voting predic ...
West Nile Neuroinvasive Disease Case Definitions Reproduced
West Nile Neuroinvasive Disease Case Definitions Reproduced

... Case genotypes were prepared from the passing exome sequencing calls of all 44 WNVE subjects. In silico control genotypes were derived from 379 subjects of European ancestry included in the 1000 Genomes Project phase 1 v3.20101123 release. Case and control panels were independently filtered to exclu ...
Slide Presentation
Slide Presentation

... substitutions 4 are involved in brain development or function! Eight of 10 are transcribed, while the other 2 are predicted genes, transcribed in mammals. ...
HW2-1
HW2-1

... 4. Can you generate some visual diagnostic figures to check your overall data quality? ...
E. coli(λ) - UCSF Biochemistry
E. coli(λ) - UCSF Biochemistry

Gene transfer from organelles to the nucleus: Frequent and in big
Gene transfer from organelles to the nucleus: Frequent and in big

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Pathogenomics

Pathogen infections are among the leading causes of infirmity and mortality among humans and other animals in the world. Until recently, it has been difficult to compile information to understand the generation of pathogen virulence factors as well as pathogen behaviour in a host environment. The study of Pathogenomics attempts to utilize genomic and metagenomics data gathered from high through-put technologies (e.g. sequencing or DNA microarrays), to understand microbe diversity and interaction as well as host-microbe interactions involved in disease states. The bulk of pathogenomics research concerns itself with pathogens that affect human health; however, studies also exist for plant and animal infecting microbes.
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