A Long-Term Evolutionary Pressure on the Amount of Noncoding DNA
... On the one hand, variability is a prerequisite for evolvability, the ability to innovate (Wagner and Altenberg 1996; Kirschner and Gerhart 1998; Radman et al. 1999; Burch and Chao 2000; Wagner 2005). On the other hand, the long-term evolutionary success also requires that a sufficient proportion of ...
... On the one hand, variability is a prerequisite for evolvability, the ability to innovate (Wagner and Altenberg 1996; Kirschner and Gerhart 1998; Radman et al. 1999; Burch and Chao 2000; Wagner 2005). On the other hand, the long-term evolutionary success also requires that a sufficient proportion of ...
The CHARGE Targeted Sequencing Study
... of MAF, and summed to create a Q statistic. The significance of the Q statistics was determined using an asymptotic distribution, as described in Wu et al.36 The Q statistic, calculated by taking the weighted squared z score for each variant and dividing by the total Q statistic, can be used to iden ...
... of MAF, and summed to create a Q statistic. The significance of the Q statistics was determined using an asymptotic distribution, as described in Wu et al.36 The Q statistic, calculated by taking the weighted squared z score for each variant and dividing by the total Q statistic, can be used to iden ...
Sequence analysis of the GP, NP, VP40 and VP24 genes of Ebola
... One feature of members of the family Filoviridae is the contrast between the high genetic diversity between subtypes and the low intrasubtype variability. Indeed, the Booue! strain diverges from other strains of the Zaire subtype by only 1–2 %, despite the fact that Booue! -96 and Zaire-76\95 were i ...
... One feature of members of the family Filoviridae is the contrast between the high genetic diversity between subtypes and the low intrasubtype variability. Indeed, the Booue! strain diverges from other strains of the Zaire subtype by only 1–2 %, despite the fact that Booue! -96 and Zaire-76\95 were i ...
02/04
... There are three stop (termination) codons. They are often called nonsense codons. Genetic Code is degenerate. Some amino acids are encoded by more than one codon. ...
... There are three stop (termination) codons. They are often called nonsense codons. Genetic Code is degenerate. Some amino acids are encoded by more than one codon. ...
Common DNA sequences with potential for detection of genetically
... systems may be eliminated from genetically modified plants prior to their application in the field. Herbicide resistance markers (Table 1) are less likely than antibiotic markers to be removed from plant cells prior to release into the field since they can be exploited by the plant grower. The need ...
... systems may be eliminated from genetically modified plants prior to their application in the field. Herbicide resistance markers (Table 1) are less likely than antibiotic markers to be removed from plant cells prior to release into the field since they can be exploited by the plant grower. The need ...
"Using Model Organism Databases (MODs)". In: Current - SGD-Wiki
... and approaches for accessing, browsing, and querying these data. Curr. Protoc. Essential C 2009 by John Wiley & Sons, Inc. Lab. Tech. 1:11.4.1-11.4.17. Keywords: Genome project r genetics r DNA sequence r gene model r protein function ...
... and approaches for accessing, browsing, and querying these data. Curr. Protoc. Essential C 2009 by John Wiley & Sons, Inc. Lab. Tech. 1:11.4.1-11.4.17. Keywords: Genome project r genetics r DNA sequence r gene model r protein function ...
Bioinfo_Course_Rotterdam
... A bit of history will explain some terms and avoid further confusion. In the 1980s, several databases started to collect sequence information: GenBank in the USA, EMBL in Europe and DDBJ in Japan for DNA; SwissProt in Switzerland and PIR in the USA for proteins; PDB in the USA for protein structures ...
... A bit of history will explain some terms and avoid further confusion. In the 1980s, several databases started to collect sequence information: GenBank in the USA, EMBL in Europe and DDBJ in Japan for DNA; SwissProt in Switzerland and PIR in the USA for proteins; PDB in the USA for protein structures ...
Article A Molecular Evolutionary Reference for the Human Variome
... et al. 2010) contains 20,957 deleterious single nucleotide polymorphisms (SNPs) associated with diseases (positive controls) and 18,411 common population polymorphisms (negative controls). EPs showed a quickly rising receiver operating characteristic (ROC) curve that contrasts the false positive and ...
... et al. 2010) contains 20,957 deleterious single nucleotide polymorphisms (SNPs) associated with diseases (positive controls) and 18,411 common population polymorphisms (negative controls). EPs showed a quickly rising receiver operating characteristic (ROC) curve that contrasts the false positive and ...
Finding Patterns in Protein Sequence and Structure
... Given an HMM and a sequence of observations, what is the probability that the observations are generated by the model? (2) The Decoding Problem Given a model and a sequence of observations, what is the most likely state sequence in the model that produced the observations? (3) The Learning Problem G ...
... Given an HMM and a sequence of observations, what is the probability that the observations are generated by the model? (2) The Decoding Problem Given a model and a sequence of observations, what is the most likely state sequence in the model that produced the observations? (3) The Learning Problem G ...
Distribution and characteristic of nitrite-dependent anaerobic
... Segarra et al., 2013) and manganese (Egger et al., 2015), the coupling of AOM to nitrite reduction process, named as nitrite-dependent anaerobic methane oxidation (n-damo), has also been demonstrated (Raghoebarsing et al., 2006) N-damo process is performed by ‘‘Candidatus Methylomirabilis oxyfera’’ ...
... Segarra et al., 2013) and manganese (Egger et al., 2015), the coupling of AOM to nitrite reduction process, named as nitrite-dependent anaerobic methane oxidation (n-damo), has also been demonstrated (Raghoebarsing et al., 2006) N-damo process is performed by ‘‘Candidatus Methylomirabilis oxyfera’’ ...
Identification, characterization, and expression profiling of salt
... affects G. hirsutum; however, G. arboreum shows good resistance against salt stress. The complete genome sequence of G. arboreum has been predicted. This species has 41,330 protein-coding genes (Li et al., 2014). To identify salt-stress tolerance gene(s) from cotton plants, the differential display ...
... affects G. hirsutum; however, G. arboreum shows good resistance against salt stress. The complete genome sequence of G. arboreum has been predicted. This species has 41,330 protein-coding genes (Li et al., 2014). To identify salt-stress tolerance gene(s) from cotton plants, the differential display ...
Ab initio gene prediction
... probability of being in an intron “state” (based solely on donor sites) Note – these probabilities are qualitative and are intended only to portray the local trends. ...
... probability of being in an intron “state” (based solely on donor sites) Note – these probabilities are qualitative and are intended only to portray the local trends. ...
RTPrimerDB: the real-time PCR primer and probe database, major
... pipeline for real-time quantitative PCR assays. Over the last year the number of user submitted assays has grown to 3500. Data conveyance from Entrez Gene by establishing an assay-to-gene relationship enables the addition of new primer assays for one of the 1.5 million different genes from 2300 spec ...
... pipeline for real-time quantitative PCR assays. Over the last year the number of user submitted assays has grown to 3500. Data conveyance from Entrez Gene by establishing an assay-to-gene relationship enables the addition of new primer assays for one of the 1.5 million different genes from 2300 spec ...
MtHap_GWA_README
... shell scripts and R is necessary for successfully performing an analysis using these functions. Many people contributed to this code, but I am solely responsible for any errors. Please contact me directly ([email protected]) with any bugs. While I have made every effort to ensure that the results are ...
... shell scripts and R is necessary for successfully performing an analysis using these functions. Many people contributed to this code, but I am solely responsible for any errors. Please contact me directly ([email protected]) with any bugs. While I have made every effort to ensure that the results are ...
The study of threshold determination of gene identification and its
... DNA is the carrier of biological genetic information. It uses genetic code to store information, and guides the synthesis of proteins. The accurate deliver of genetic information of protein could make the various life functions completely. Along with the successful completion of world human genome p ...
... DNA is the carrier of biological genetic information. It uses genetic code to store information, and guides the synthesis of proteins. The accurate deliver of genetic information of protein could make the various life functions completely. Along with the successful completion of world human genome p ...
Leroy et. Al. Gabon 96 phylogeny
... One feature of members of the family Filoviridae is the contrast between the high genetic diversity between subtypes and the low intrasubtype variability. Indeed, the Booue! strain diverges from other strains of the Zaire subtype by only 1–2 %, despite the fact that Booue! -96 and Zaire-76\95 were i ...
... One feature of members of the family Filoviridae is the contrast between the high genetic diversity between subtypes and the low intrasubtype variability. Indeed, the Booue! strain diverges from other strains of the Zaire subtype by only 1–2 %, despite the fact that Booue! -96 and Zaire-76\95 were i ...
Consulta: subjectFacets:"16S rRNA" Registros recuperados: 43
... A reverse transcriptase - polymerase chain reaction based assay for Borrelia species detection in ticks was developed. The method was based on amplification of 552 nucleotide bases long sequence of 16S rRNA, targeted by Borrelia specific primers. In the present study, total RNA extracted from Ixodes ...
... A reverse transcriptase - polymerase chain reaction based assay for Borrelia species detection in ticks was developed. The method was based on amplification of 552 nucleotide bases long sequence of 16S rRNA, targeted by Borrelia specific primers. In the present study, total RNA extracted from Ixodes ...
Basic Aquaculture Genetics
... offspring. In a way, the XO sex-determination system is similar to the XY sex-determination system except that in the XO system the males contain just one set of sex chromosomes (X). Several other sex-determining systems have been discovered in fish. Many of these systems are more complex than the X ...
... offspring. In a way, the XO sex-determination system is similar to the XY sex-determination system except that in the XO system the males contain just one set of sex chromosomes (X). Several other sex-determining systems have been discovered in fish. Many of these systems are more complex than the X ...
Finding Patterns in Protein Sequence and Structure
... Interpolated Markov Models • We can make the weights depend on the history – for a given order, we may have significantly more data to estimate some words than others • General linear interpolation ...
... Interpolated Markov Models • We can make the weights depend on the history – for a given order, we may have significantly more data to estimate some words than others • General linear interpolation ...
REVIEW Pathways to understanding the extended phenotype of
... Direct sequencing of RNA to generate expressed sequence tags aids in accurate genome annotation, by allowing fine-scale definition of gene structure and estimating gene expression levels under different conditions. Even in species with well-characterized genes, gene prediction tools are imprecise, s ...
... Direct sequencing of RNA to generate expressed sequence tags aids in accurate genome annotation, by allowing fine-scale definition of gene structure and estimating gene expression levels under different conditions. Even in species with well-characterized genes, gene prediction tools are imprecise, s ...
Chapter 21
... fragments directly • Powerful computer programs are used to order fragments into a continuous sequence ...
... fragments directly • Powerful computer programs are used to order fragments into a continuous sequence ...
Chapter 21 Genomes
... fragments directly • Powerful computer programs are used to order fragments into a continuous sequence ...
... fragments directly • Powerful computer programs are used to order fragments into a continuous sequence ...
Ch 21
... fragments directly • Powerful computer programs are used to order fragments into a continuous sequence ...
... fragments directly • Powerful computer programs are used to order fragments into a continuous sequence ...
PDF file
... 152-800 and 268-580 Both markers present – Assumed to be resistant Both markers absent – Assumed to be susceptible 87 recombinants (one marker present and the other absent) were identified – inoculated in the ...
... 152-800 and 268-580 Both markers present – Assumed to be resistant Both markers absent – Assumed to be susceptible 87 recombinants (one marker present and the other absent) were identified – inoculated in the ...
An Evaluation of Microarray Visualization Tools for Biological Insight
... How do various visualization techniques affect the users’ perception of data? How does users’ background affect the tool usage? How do these tools support hypothesis generation? Can insight be measured in a controlled experiment? ...
... How do various visualization techniques affect the users’ perception of data? How does users’ background affect the tool usage? How do these tools support hypothesis generation? Can insight be measured in a controlled experiment? ...
Metagenomics
Metagenomics is the study of genetic material recovered directly from environmental samples. The broad field may also be referred to as environmental genomics, ecogenomics or community genomics. While traditional microbiology and microbial genome sequencing and genomics rely upon cultivated clonal cultures, early environmental gene sequencing cloned specific genes (often the 16S rRNA gene) to produce a profile of diversity in a natural sample. Such work revealed that the vast majority of microbial biodiversity had been missed by cultivation-based methods. Recent studies use either ""shotgun"" or PCR directed sequencing to get largely unbiased samples of all genes from all the members of the sampled communities. Because of its ability to reveal the previously hidden diversity of microscopic life, metagenomics offers a powerful lens for viewing the microbial world that has the potential to revolutionize understanding of the entire living world. As the price of DNA sequencing continues to fall, metagenomics now allows microbial ecology to be investigated at a much greater scale and detail than before.