• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Genome position and gene amplification | SpringerLink
Genome position and gene amplification | SpringerLink

... these cells with respect to site specific response to drug challenge. We used array comparative genomic hybridization (CGH) to identify and classify the types of genomic alterations in the drug resistant cells, fluorescent in situ hybridization (FISH) to study the organization and mechanism of ampli ...
SimBac: simulation of whole bacterial genomes with homologous
SimBac: simulation of whole bacterial genomes with homologous

... hypotheses and checking the performance of other methods in extracting valuable information from data. Previous software specifically developed for simulating bacterial evolution is limited in applicability, having been conceived for limited data and biological phenomena. We present SimBac, a new si ...
PDF version - Atlas of Genetics and Cytogenetics in Oncology and
PDF version - Atlas of Genetics and Cytogenetics in Oncology and

... homologous end joining (NHEJ) VI.3.3. During mitosis, separation of centromeres in dicentric chromosomes to opposite poles produces an anaphase bridge, followed by chromosome breakage, subsequent fusion of damaged ends, and promotion of additional BFB cycles VI.3.4. Recurring cycles of gene amplific ...
in vitro
in vitro

... Some of the drawbacks of these methods are: •The inserted DNA randomly integrates into the genome •The eggs must be harvested & fertilized in vitro •More than one copy of the gene may get into the genome ...
in vitro
in vitro

... Some of the drawbacks of these methods are: •The inserted DNA randomly integrates into the genome •The eggs must be harvested & fertilized in vitro •More than one copy of the gene may get into the genome ...
sample - Test Bank Team
sample - Test Bank Team

... 42) What was the purpose of genetically modifying the following plants: corn, soybeans, rice, cotton, sugar beets, and canola? Answer: herbicide resistance Section: 1.5 43) What term is applied to a variety of projects whereby genome sequences are deposited in databases for research purposes? Answer ...
Cloning, characterization and in vitro and in planta expression of a
Cloning, characterization and in vitro and in planta expression of a

Viruses
Viruses

... • Viruses identify their hosts by a lock and key mechanism. However some viruses have wider range than others such as swine flue virus can infect both humans and hogs while rabies virus can infect a number of mammalian species including raccoons, skunks, dogs and humans. • Viruses of eukaryotes are ...
Pleurochrysome: A Web Database of
Pleurochrysome: A Web Database of

... database (nt), EST database (dbEST) and protein database (nr) using each UNIGENE sequence as a query. Applying 1E10 as a threshold e-value, 3,215 UNIGENEs were annotated with at least one similar sequence in the databases. Conserved domain information and Gene Ontology (GO) information were retrieve ...
CHAPTER  1 LITERATURE  SURVEY
CHAPTER 1 LITERATURE SURVEY

... as in other members of the order Mononegavirales, is controlled by the highly conserved order of the genes relative to the single transcriptional promoter at the 3' end of the viral genome through progressive transcriptional attenuation at the intergenic junctions. By rearranging the gene order in a ...
Genetic analysis of TTF2 gene in congenital hypothyroid infants with
Genetic analysis of TTF2 gene in congenital hypothyroid infants with

... thyroid gland is abnormally located in a sublingual position so called Thyroid ectopy) and thyroid hypoplasia (the thyroid gland is severely reduced in size resulted from remnants of thyroid tissue in the normal position).6,7 Some cases of dysgenesis are now discovered to be the result of mutations ...
8 MITOCHONDRIAL INHERITANCE — Complex Patterns of
8 MITOCHONDRIAL INHERITANCE — Complex Patterns of

... This leads to a reduction in the supply of ATP, and may result in problems with the body’s functions The pattern of inheritance of conditions due to faulty mitochondrial genes is often called maternal inheritance. This is because a child inherits the great majority of their mitochondria from their m ...
Missense mutations in the PAX6 gene in aniridia.
Missense mutations in the PAX6 gene in aniridia.

... he Pax gene consists of a family of developmental control genes; nine members have been isolated in vertebrates since paired originally was identified as a segmentation gene in Drosophila melanogaster.1-2 The encoded proteins are transcriptional regulators with DNA binding through a conserved domain ...
Genes can be switched on and off by the protein CTCF
Genes can be switched on and off by the protein CTCF

Sequences 5` to Translation Start Regulate
Sequences 5` to Translation Start Regulate

... show a high level of nucleotide sequence homology among all petunia rbcS genes are hatched. Experiments described in the preceding paper (Dean et al., 1989) using fusions between SSU301 and SSU911 showed that sequences downstream of the coding region contribute significantly to the quantitative diff ...
Missense mutations in the PAX6 gene in aniridia.
Missense mutations in the PAX6 gene in aniridia.

... he Pax gene consists of a family of developmental control genes; nine members have been isolated in vertebrates since paired originally was identified as a segmentation gene in Drosophila melanogaster.1-2 The encoded proteins are transcriptional regulators with DNA binding through a conserved domain ...
The Study of Genetics: A Historical Perspective Ross Edwards
The Study of Genetics: A Historical Perspective Ross Edwards

... show what was occurring. He realized that each plant must have two traits, one inherited from each parent (Mawer 2006). By crossing Aa with Aa we would achieve three different variations: AA (25%) , Aa (50%), and aa (25%). In addition to this, he found that by combining multiple trait pairs (i.e. Aa ...
Expansion of tandem repeats and oligomer
Expansion of tandem repeats and oligomer

... with  ranging between 2 and 5 for di erent organisms. In this case, these distributions should be straight lines on a double logarithmic plot. In fact, that is what we observe from Figs. 1b and 2b. We do not observe a signi cant statistical di erence in the functional behavior of N0 (‘) for introns ...
Functional Analysis of A Novel Splicing Mutation in The Mutase
Functional Analysis of A Novel Splicing Mutation in The Mutase

... intronic regions near the splice junctions can affect mRNA splicing, altering the resultant RNA sequence, which could have a profound impact on protein expression (10). It is important to note that at least 200 mutations in MUT have been identified (11). In addition, a number of ethnic-specific muta ...
Presentation: Computation to Solve Problems
Presentation: Computation to Solve Problems

Comparative Bacterial Genomics Genome Databases
Comparative Bacterial Genomics Genome Databases

... jor source of genomic sequence data. The website http://www.ncbi.nlm.nih.gov/genome/ browse/ lists thousands of Prokaryotic genome sequence projects. Each genome replicon is represented by a unique ID accession number, which is the same across major databases in the US (GenBank) Europe (EMBL) and t ...
Genetics 2
Genetics 2

... Notice that when Lilly is crossed with Herman, we would predict that half the offspring would be “Ww”, the other half would be “ww” Half “Ww”, Heterozygous, and will have a widows peak Half “ww”, Homozygous, and will not have a widows peak ...
RNA-guided gene drives can efficiently bias inheritance in wild yeast
RNA-guided gene drives can efficiently bias inheritance in wild yeast

... eukaryotic organisms as predicted. By itself this does not guarantee the success of gene drives in other organisms as the rate of homologous recombination varies between species and is known to be particularly high in yeast. However, the fact that we observed inheritance biasing rates equal to or ex ...
Identification of Short Motifs for Comparing Biological Sequences
Identification of Short Motifs for Comparing Biological Sequences

... For example, sequences that carry the same restriction enzymes’ cut positions [16] might be related and would have similar functions. It would be the same with sequences that carry transcription factor binding sites; other signals would be motifs of specific nature, unique shortest substrings [17] w ...
Amplification of a DNA Fragment Using Polymerase
Amplification of a DNA Fragment Using Polymerase

... In this experiment, you will amplify a fragment of pBluescript II (a plasmid), which includes the multiple cloning site (MCS) of the vector (Fig. 24-2). The pBluescript II plasmid comes in the S/K form and the K/S form. These two plasmids are identical except for the orientation of the MCS (see Fig. ...
< 1 ... 60 61 62 63 64 65 66 67 68 ... 445 >

Genome editing

Genome editing, or genome editing with engineered nucleases (GEEN) is a type of genetic engineering in which DNA is inserted, replaced, or removed from a genome using artificially engineered nucleases, or ""molecular scissors."" The nucleases create specific double-stranded break (DSBs) at desired locations in the genome, and harness the cell’s endogenous mechanisms to repair the induced break by natural processes of homologous recombination (HR) and nonhomologous end-joining (NHEJ). There are currently four families of engineered nucleases being used: Zinc finger nucleases (ZFNs), Transcription Activator-Like Effector Nucleases (TALENs), the CRISPR/Cas system, and engineered meganuclease re-engineered homing endonucleases.It is commonly practiced in genetic analysis that in order to understand the function of a gene or a protein function one interferes with it in a sequence-specific way and monitors its effects on the organism. However, in some organisms it is difficult or impossible to perform site-specific mutagenesis, and therefore more indirect methods have to be used, such as silencing the gene of interest by short RNA interference (siRNA) . Yet gene disruption by siRNA can be variable and incomplete. Genome editing with nucleases such as ZFN is different from siRNA in that the engineered nuclease is able to modify DNA-binding specificity and therefore can in principle cut any targeted position in the genome, and introduce modification of the endogenous sequences for genes that are impossible to specifically target by conventional RNAi. Furthermore, the specificity of ZFNs and TALENs are enhanced as two ZFNs are required in the recognition of their portion of the target and subsequently direct to the neighboring sequences.It was chosen by Nature Methods as the 2011 Method of the Year.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report