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DNA webquest!!
DNA webquest!!

... Second Site: http://gslc.genetics.utah.edu/units/basics/tour/. 1. What is DNA? 2. What does “DNA” stand for? __________________________________ 3. What is the four-letter DNA alphabet and what are the special rules by which the alphabet pieces bond together? ...
Bioinformatics and Computational Bology notes
Bioinformatics and Computational Bology notes

... • field of science in which biology, computer science, and information technology merge to form a single discipline ...
Biology 303 EXAM II 3/14/00 NAME
Biology 303 EXAM II 3/14/00 NAME

... A. genomes of different individuals are even more similar than previously thought B. genomes of different individuals display greater diversity than previously thought. C. the number of different human genes is greater than 50,000 D. the human and dog genomes are virtually identical. ...
slides
slides

... •  >80%  of  the  genome  is  funcFonal  as  regulatory  sequences,  based   on  the  analysis  of  ENCODE  data   ...
Invention Fact Sheet  - Lemelson
Invention Fact Sheet - Lemelson

... Erez Lieberman-Aiden: Notable Inventions Hi-C: 3-D Genome Sequencing Scientists have known for decades that a few dozen bases of DNA fold up into a double helix, but have not fully understood how the three billion base-pair long genome – 2 meters in length when stretched out – folds to fit into the ...
Click Here
Click Here

... The introduction of a higher number of haplotypes for GRCh37 added an extra level of complexity to the gene annotation process as only the best alignment for each individual sequence gets selected for gene annotation. We have developed a method to project the annotation between the reference chromos ...
Mutations
Mutations

... sequences of DNA bases and split each DNA strand at a specific site within that sequence.  This one recognizes the base sequence "G-A-A T-T-C" and cuts each strand between the "G" and the "A" as shown by the red ...
Gene 5102-96
Gene 5102-96

Notes - MyWeb
Notes - MyWeb

... An individual with brown and blue alleles of the bey2 gene on chromosome 15. There are two copies of chromosome 15. Each copy has the bey2 gene. On one copy the bey2 gene is in the brown allele, in the other the bey2 gene is in the blue allele. The difference between the brown and blue alleles is du ...
Genetically Modified Food
Genetically Modified Food

... Mechanism1 : Isolating/synthesizing the target gene  The ‘shotgun’ approach, using type II restriction enzyme(restriction endonuclease ) - the enzyme cuts at recognition sites, to obtain a desired gene - sticky ends or blunt ends produced (there are figures later)  Making a copy of the gene from ...
Gene Section P53 (protein 53 kDa) Atlas of Genetics and Cytogenetics
Gene Section P53 (protein 53 kDa) Atlas of Genetics and Cytogenetics

... P53 is mutated in about 50% of human cancers, and the non-mutated allele is generally lost; the frequency and the type of mutation may vary from one tumor type to another; in general, mutations are found in the central part (exons 4-8) of the p53 gene; these mutations are missense, non-sense, deleti ...
In the 150 years since Darwin wrote On the Origin of Species our
In the 150 years since Darwin wrote On the Origin of Species our

... causes a build up of the amino acid ornithine. This defect is caused by 35 different mutations in a single gene and so finding preventative drugs specific to each mutation would take an extremely long time to develop. (III) “Struggle for existence” Due to advances in genetic diagnosis, rogue genes m ...
Document
Document

... c. Binding of specialized transription factors (repressors) to proximal and distal control elements can prevent transcription 5. Gene regulation is also possible after transcription a. Alternative RNA splicing allows multiple proteins to be made from a gene (19.8) b. mRNA lifespan determines how muc ...
- PhagesDB
- PhagesDB

... Interestingly, both gp15 & gp17 give good hits as encoding a major tail subunit protein. We not that the closely related AM cluster Circum genome homologs have been annotated as capsid genes. We feel these two related homolog are in fact MCP genes. Gp96 gives really good blast hits to homologs of ta ...
Salmonella typhimurium
Salmonella typhimurium

... more likely to have a mixture of tall and short alleles than all tall or all short ...
1 The structure and replication of DNA
1 The structure and replication of DNA

... The process by which a cell develops more specialised functions by expressing the genes characteristic for that type of cell. - Differentiation into specialised cells from meristems in plants; embryonic and tissue (adult) stem cells in animals. - Meristems are regions of unspecialised cells in plant ...
Unit 1 DNA and the Genome Summary
Unit 1 DNA and the Genome Summary

... DNA is tightly coiled and packaged with associated proteins. 2. Replication of DNA (a) Prior to cell division DNA is replicated by DNA polymerase. A primer is required to start replication. - DNA is unwound and unzipped to form two template strands. This process occurs at several locations o the DNA ...
Mutations - KingsfieldBiology
Mutations - KingsfieldBiology

... DNA of an organism is known as a mutation.  Mutations can occur in either somatic cells (body cell) and germ cells (those that produce the gametes (these can be passed on!)).  Changes in the structure or number of a whole chromosome is know as a chromosome mutation  Changes which affect a single ...
Gramene: A Resource for Comparative Grass Genomics
Gramene: A Resource for Comparative Grass Genomics

... An ontology matches classification and reasoning methods of the computer. Ontologies can be indexed “objectively” by a computer.\ Computers can infer new knowledge ...
Module name Genetics - a basic course Module code B
Module name Genetics - a basic course Module code B

... connection of genotype and phenotype. SKILLS -Understanding the logic and core concepts of classical and molecular genetics, including: prediction of genotypic and phenotypic ratios for complex crosses; mechanisms of DNA replication, recombination, transcription and gene expression. -Explaining how ...
dna_notes - KScience
dna_notes - KScience

...  Substitutions – a base is replaced with a different base. Mutations are sometimes beneficial because they generate variability, which is the basis of natural selection. Mutations are more often deleterious because selection in a species has selected for the genome it now has and changes are theref ...
ppt - Barley World
ppt - Barley World

... “Our work suggests that cisgenic insertion of additional copies of native genes involved in growth regulation may provide tools to help modify plant architecture, expand the genetic variance in plant architecture available to breeders and accelerate transfer of alleles between difficult-to-cross ...
zChap00_Front_140901
zChap00_Front_140901

Genetics 1
Genetics 1

... physical and mental traits of their parents or ancestors i.e. certain traits are transmitted from one generation to the next. Genetic information is carried on the DNA molecule as a gene. Gene: is the unit of heredity found on a chromosome, and is an instruction (code) to the cell to make a particul ...
DNA Worksheet
DNA Worksheet

... 23. Use the amino acid chart in your notes to translate the sequence of codons (from #16) and write the ...
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Genome editing

Genome editing, or genome editing with engineered nucleases (GEEN) is a type of genetic engineering in which DNA is inserted, replaced, or removed from a genome using artificially engineered nucleases, or ""molecular scissors."" The nucleases create specific double-stranded break (DSBs) at desired locations in the genome, and harness the cell’s endogenous mechanisms to repair the induced break by natural processes of homologous recombination (HR) and nonhomologous end-joining (NHEJ). There are currently four families of engineered nucleases being used: Zinc finger nucleases (ZFNs), Transcription Activator-Like Effector Nucleases (TALENs), the CRISPR/Cas system, and engineered meganuclease re-engineered homing endonucleases.It is commonly practiced in genetic analysis that in order to understand the function of a gene or a protein function one interferes with it in a sequence-specific way and monitors its effects on the organism. However, in some organisms it is difficult or impossible to perform site-specific mutagenesis, and therefore more indirect methods have to be used, such as silencing the gene of interest by short RNA interference (siRNA) . Yet gene disruption by siRNA can be variable and incomplete. Genome editing with nucleases such as ZFN is different from siRNA in that the engineered nuclease is able to modify DNA-binding specificity and therefore can in principle cut any targeted position in the genome, and introduce modification of the endogenous sequences for genes that are impossible to specifically target by conventional RNAi. Furthermore, the specificity of ZFNs and TALENs are enhanced as two ZFNs are required in the recognition of their portion of the target and subsequently direct to the neighboring sequences.It was chosen by Nature Methods as the 2011 Method of the Year.
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