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GenomeAnnot - Nematode bioinformatics. Analysis tools and data
GenomeAnnot - Nematode bioinformatics. Analysis tools and data

... bioinformatics skills. •Con: makes it difficult to perform large-scale data mining. •Solution: enable more experienced users to retrieve the data they require and to run analyses locally. ...
1-1 - We can offer most test bank and solution manual you need.
1-1 - We can offer most test bank and solution manual you need.

... that require their host cells for survival. ...
Microbial Taxonomy Traditional taxonomy or the classification
Microbial Taxonomy Traditional taxonomy or the classification

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speciation (formation of new species)
speciation (formation of new species)

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Chapter 9 - HCC Learning Web
Chapter 9 - HCC Learning Web

... homology with genes of known function. The best way to identify gene function is to look at their proteins (i.e. BLASTp search) ...
Genetic Technology 13.1 and 13.2 notes
Genetic Technology 13.1 and 13.2 notes

... • Definition: the choosing of plants/animals with the most desired traits to serve as parents of the next generation. • Requires time, patience and several generations. • Examples: Milk production in cattle, planting seeds from the ...
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No Slide Title

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... Predict the number and the size of restriction fragments obtained by digestion of Lambda DNA with the restriction enzyme BssHI (5' GCGCGC 3'). A. SIZE of fragments = 46 = 4,096 base pairs B. NUMBER of fragments = 50kb / 4.096 kb = 12 fragments C. You isolate the double-stranded DNA genome of a diffe ...
Genetics – Human Genetic Disorders and Genetic Engineering
Genetics – Human Genetic Disorders and Genetic Engineering

... from many cells into manageable pieces. 2. There will be a collection of copies of fragment 1, which is a different size than fragment 2, and so on. 3. The pieces can be ordered according to size using gel electrophoresis (moving the fragments in an electric field through a gel matrix). Larger piece ...
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Genetic Engineering
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... are taken from a cell sample, cut out and matched up in pairs • Humans have 23 pairs of chromosomes • Karyotypes can be used to determine if genetic disorder is present • If too many are present can indicate Down’s syndrome • If some are missing can indicate Turner’s syndrome ...
Cow DNA: How DNA Controls the Workings of the Cell
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... We have sequenced the genome of the filamentous ascomycete Ashbya gossypii and produced a complete annotation of the 4718 protein coding genes. (GenBank accession numbers AE016814-AE016821). The systematic gene nomenclature follows that used for Saccharomyces cerevisiae. This facilitated the alignme ...
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... makes up a gene. It ranges in size from one DNA base to a large segment of a chromosome. Gene mutations can be inherited from a parent or acquired during a person’s lifetime. If a mutation occurs in an egg or sperm cell during a person’s life, there is a chance that the person’s children will inheri ...
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Genome editing

Genome editing, or genome editing with engineered nucleases (GEEN) is a type of genetic engineering in which DNA is inserted, replaced, or removed from a genome using artificially engineered nucleases, or ""molecular scissors."" The nucleases create specific double-stranded break (DSBs) at desired locations in the genome, and harness the cell’s endogenous mechanisms to repair the induced break by natural processes of homologous recombination (HR) and nonhomologous end-joining (NHEJ). There are currently four families of engineered nucleases being used: Zinc finger nucleases (ZFNs), Transcription Activator-Like Effector Nucleases (TALENs), the CRISPR/Cas system, and engineered meganuclease re-engineered homing endonucleases.It is commonly practiced in genetic analysis that in order to understand the function of a gene or a protein function one interferes with it in a sequence-specific way and monitors its effects on the organism. However, in some organisms it is difficult or impossible to perform site-specific mutagenesis, and therefore more indirect methods have to be used, such as silencing the gene of interest by short RNA interference (siRNA) . Yet gene disruption by siRNA can be variable and incomplete. Genome editing with nucleases such as ZFN is different from siRNA in that the engineered nuclease is able to modify DNA-binding specificity and therefore can in principle cut any targeted position in the genome, and introduce modification of the endogenous sequences for genes that are impossible to specifically target by conventional RNAi. Furthermore, the specificity of ZFNs and TALENs are enhanced as two ZFNs are required in the recognition of their portion of the target and subsequently direct to the neighboring sequences.It was chosen by Nature Methods as the 2011 Method of the Year.
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