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Chp 12 Notes
Chp 12 Notes

... g. X-Linked Genes: found on the X chromosome h. Y-Linked Genes: found on the Y chromosome i. Because males have only one X chromosome they will exhibit any X linked gene 2. Linked Genes a. Linked Genes: pairs of genes that tend to be inherited together b. Linkage Group: set of linked genes (Genes on ...
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The Genetics of Cancer

... Tumor suppressor genes • Cancer can be caused by loss of genes that inhibit cell division. • Tumor suppressor genes normally stop a cell from dividing. • Mutations of both copies of a tumor suppressor gene is usually required to allow cell division. ...
Extra Homework problems
Extra Homework problems

Slide 1
Slide 1

... exons are each separated by an intron. The five exons are W, X, Alpha, Beta, and Z. Two types of protein are found. The alpha form consists of exons W, X, alpha and Z. The beta form consists of the W, X, Beta and Z exons. The two different types of the protein are produced by alternative splicing of ...
Evolutionary Mechanisms and Processes
Evolutionary Mechanisms and Processes

... Despite the fact that their complexity is a characteristic, and possibly the most prominent property of living systems, it probably does not originate as the product of an active evolutionary trend. The high complexity and level of orderliness of living systems seem to be the result of their physica ...
The Coalescent Theory
The Coalescent Theory

... • Assume no recombination between sequences • N sequences are connected by a single phylogenetic tree (genealogy) where the root=MRCA MRCA ...
Somatic BRAF Mutation - Lynch Syndrome Screening Network
Somatic BRAF Mutation - Lynch Syndrome Screening Network

Biology
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... Crossing over, jumping genes, deletion and duplication of genes results in genetic variations---Chapter 12-4 How mutations can alter genetic information and the possible consequences ...
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... describes the overall process how cells convert an extracellular signal into a specific cellular response and includes several intracellular signaling pathways. However, there are many common features which are found in most signal transduction pathways. a) ...
One-Gene-One-Enzyme, Pseudogenes... ppt
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... Analysis • Any one of thousands of possible mutations in the several genes for a biochemical pathway could explain why a particular species fails to make a particular enzyme. • What does this suggest about the fact that Vitamin C production is blocked in several similar species by the exact same mu ...
CHROMOSOMAL LOCATION: 5q13.2 MODE OF INHERIT
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... Congenital adrenal hyperplasia (CAH), with an incidence rate of 1 in 10,000 to 18,000 live births, is one of the most common inherited syndromes. The condition is characterized by impaired cortisol production due to inherited defects in steroid biosynthesis. The clinical consequences of CAH, besides ...
Genetic Epidemiology of High Blood Pressure in Chinese
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Year 10 CB3 - Bedford Free School
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... Bases – a substance that helps make up DNA. There are four bases in DNA, shown by the letters A, C, G and T. Chromosome – a thread-like structure found in the nuclei of cells. Each chromosome contains one long DNA molecule packed with proteins. Complementary base pairs - two DNA bases that fit into ...
The Price of Silent Mutations
The Price of Silent Mutations

... mutation would be tolerated. A striking exam- translation process and protein folding can ocple of the damage a mutation in a splicing en- cur simultaneously, the researchers theorized hancer can do was recently documented by that the rarer synonymous codon produced by Francisco Baralle of the Inter ...
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... the termination factor, such as rho, would always have access to its binding site on the RNA transcript (in the case of rho, it bind to the rut sequence). When translation is actively occurring, the ribosomes may cover or hide the binding site preventing the termination factor from functioning. (Or ...
Learner outcomes File
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... F- Genetic engineering and biotechnology (Topic 4.4) - Outline the use of polymerase chain reaction (PCR) to copy and amplify minute quantities of DNA. - State that, in gel electrophoresis, fragments of DNA move in an electric field and are separated according to their size. - State that gel electro ...
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... 1) Two students were testing the amount of fertilizer that would best promote the growth of strawberries in a garden. Which of the following could be an unavoidable source of experimental error? A) length of the study B) variation in the strawberry plants C) the cost of watering the plants D) fertil ...
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... • Some genes cause symptoms in everyone, while others cause symptoms in a minority • Penetrance ...
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... Long QT (LQTS) and Brugada syndrome cause deaths in young individuals with structurally normal hearts. Cardiac arrhythmias include the long-QT syndrome (LQTS), the Brugada syndrome (BrS), the short-QT syndrome (SQTS) and the catecholaminergic polymorphic ventricular tachycardia (CPVT). Mutations in ...
Biology Second Semester Study Guide Molecular Genetics (Chapter
Biology Second Semester Study Guide Molecular Genetics (Chapter

... Cosmic Origins of first organic molecules (building blocks of 1 st cells). Also called “Exogenesis” (cosmic origins), but more commonly known as panspermia. The actual theory of panspermia speculates that life came to earth from another planet, perhaps being carried by a meteorite that crashed here. ...
Genetic Algorithms
Genetic Algorithms

... Replace worst ranked part of population with offspring ...
Terminator
Terminator

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... • The segment of DNA that contains the gene for a specific protein or RNA that the cell wants to produce will unwind and the complementary RNA strand will be made by incorporation the RNA nucleotides ...
Robustness
Robustness

... too high for fast replication & translation, e.g. viruses, bacteria. ...
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Mutation



In biology, a mutation is a permanent change of the nucleotide sequence of the genome of an organism, virus, or extrachromosomal DNA or other genetic elements. Mutations result from damage to DNA which is not repaired or to RNA genomes (typically caused by radiation or chemical mutagens), errors in the process of replication, or from the insertion or deletion of segments of DNA by mobile genetic elements. Mutations may or may not produce discernible changes in the observable characteristics (phenotype) of an organism. Mutations play a part in both normal and abnormal biological processes including: evolution, cancer, and the development of the immune system, including junctional diversity.Mutation can result in several different types of change in sequences. Mutations in genes can either have no effect, alter the product of a gene, or prevent the gene from functioning properly or completely. Mutations can also occur in nongenic regions. One study on genetic variations between different species of Drosophila suggests that, if a mutation changes a protein produced by a gene, the result is likely to be harmful, with an estimated 70 percent of amino acid polymorphisms that have damaging effects, and the remainder being either neutral or weakly beneficial. Due to the damaging effects that mutations can have on genes, organisms have mechanisms such as DNA repair to prevent or correct mutations by reverting the mutated sequence back to its original state.
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