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... cut the DNA in specific places  This creates different sized pieces of DNA  Everyone’s DNA will be cut into different sized pieces EXCEPT identical twins  This cut DNA is placed into an agarose gel which is then hooked to electrodes ...
DNA, Genes, and Chromosomes Guided Notes
DNA, Genes, and Chromosomes Guided Notes

... _______________ ________________________, named X and Y. Autosomes give traits such as hair color and height, while sex chromosomes are directly related to the sexual traits of an organism. Types of Cells and their Chromosomes Somatic cells, also known as _________________ ___________________ make u ...
The human genome: a prospect for paediatrics
The human genome: a prospect for paediatrics

... three thousand million base pairs; this is comparatively large. The complete sequence of the simple bacterium Escherichia coli, a mere five million base pairs, has yet to be determined. As a typical protein comprises say, three hundred amino acids, only one thousand nucleotides are required on avera ...
Evolution of genomes
Evolution of genomes

... the existence of highly repetitive non-coding DNA produced by transposable elements. ...
Uses for transgenic organisms (also called GMO`s or genetically
Uses for transgenic organisms (also called GMO`s or genetically

... testing. Mice given human Huntington’s disease and Alzheimer’s have led to breakthroughs in treatments.  Pigs (milk and chickens soon) with omega-3 fatty acids (good for the heart). The natural source of omega-3 fatty acids is some oily fishes like tuna and salmon, but they are overharvested and of ...
PUTTING DNA to WORK: High School Virtual Field Trip
PUTTING DNA to WORK: High School Virtual Field Trip

... 6. Which was faster and easier to use in finding a match for the human parainfluenza virus 3, the method using DNA letter sequences or the method using bar codes? ...
Chapter 1. Introduction
Chapter 1. Introduction

... Comparative genomics is a subdiscipline of genomic biology in which the genomic features of different organisms are compared. Genomic features may include the DNA sequence, genes and gene order, regulatory sequences, and other genomic structural features. In this branch of genomics, whole or large p ...
TOC  - G3: Genes | Genomes | Genetics
TOC - G3: Genes | Genomes | Genetics

... Raquel da Cunha, Elsa Lauwers, Mark Fiers, and Patrik Verstreken Genome editing is a powerful method to study gene function. In this work, Vilain and Vanhauwaert et al. present a novel genome editing methodology for fruit flies based on MiMIC transposons that are present throughout the genome. The me ...
Genome Assembly and Annotation
Genome Assembly and Annotation

... – ~ 45% of the human genome consists of repeats interspersed with non-repetitive sequences • Transposon derived (LINEs, SINEs) • 3 – 4% segmental duplications (> 1kb, > 90% similar), ~ 40% believed to be misassembled • Multi-gene families ...
Chapter 15 – Recombinant DNA and Genetic Engineering
Chapter 15 – Recombinant DNA and Genetic Engineering

... • 1997 – the first animal was cloned – Dolly a lamb – 1. Remove nucleus from cell – 2. Transfer nuclei from desired cells into unfertilized eggs – 3. Implant the “zygote” into surrogate mother – Since Dolly – we have cloned mice, rats, cows, cats, mules, horses, and Rhesus monkeys along with a c ...
Name Ch 12 Study Guide
Name Ch 12 Study Guide

... 12) What was her contribution to the discovery of DNA? 13) Why is the work of Rosalind Franklin overlooked in the discovery of DNA? 14) List the pieces of information about DNA structure that Rosalind Franklin discovered through her x-ray diffraction research. 15) What is DNA Replication? ...
Chapter 28: Chromosomes
Chapter 28: Chromosomes

... • MARs are A · T-rich but do not have any specific consensus sequence. – Usually contain consensus sequence for topoisomerase II – Many transcription factors also bind to MARs or adjacent to MARs ...
Genetics
Genetics

...  Genome refers to the complete set of genes that an organism ...
Genomics - WHAT IF server
Genomics - WHAT IF server

... trivial: • Small distance between adjacent genes • Co-orientation (lie on the same strand) • More reliability when these features are conserved in different species Additional arguments: • Similar functional annotations of adjacent genes • Observed co-expression • Known average operon length ...
Intro to Genetics
Intro to Genetics

... • You got 23 from your mom and 23 from your dad. ...
INS Biology Name: Winter Quarter Midterm
INS Biology Name: Winter Quarter Midterm

... c. many mRNA molecules can be transcribed from a single gene, increasing the potential rate of gene expression. d. B and C only e. A, B, and C 8. The genetic code is essentially the same for all organisms. From this, one can logically assume all of the following except a. a gene from an organism cou ...
Bioethics Lesson Plan
Bioethics Lesson Plan

... when an individual lacks a functioning copy of a particular gene. There are about 4,000 identified human genetic ...
Chapter 17 and 19
Chapter 17 and 19

... a change in the base sequence of DNA blockage of the ribosome-binding sites decreased permeability of the nuclear envelope a reduction in the number of tRNA molecules available for protein synthesis 10. A gene is usually _____. the same thing as a chromosome the information for making a polypeptide ...
Unit 5 Free Response
Unit 5 Free Response

... ii. The different results you would expect if a mutation occurred at the recognition site for enzyme Y. ...
Acquired Variation
Acquired Variation

... South side, upper branches ...
NUS Presentation Title 2006
NUS Presentation Title 2006

... • Genetic variation in regulators will result in correlated changes in the expression levels of multiple genes ...
No Slide Title
No Slide Title

... Reduced stress for parents Reduced morbidity/mortality Better chance of screening next pregnancy ...
Ch 12-15 Unit Overvi..
Ch 12-15 Unit Overvi..

... Meiosis – purpose; location; compare/contrast meiosis I and meiosis II, which is most similar to mitosis? Does meiosis I or II reduce the chromosome number by half? How is anaphase I different from anaphase II? Metaphase I from II? When does cross over take place? Independent assortment? Segregation ...
Chapter 14 Study Workbook
Chapter 14 Study Workbook

... The researchers identified markers in widely separated strands of DNA. They used “shotgun sequencing,” which uses a computer to match DNA base sequences. To identify genes, they found promoters, exons, and other sites on the DNA molecule. To locate and identify as many haplotypes (collections of lin ...
Whose DNA was sequenced for the Human Genome Project?
Whose DNA was sequenced for the Human Genome Project?

... figuring out which gene does what. Of the estimated 30,000 genes in the human genome, we have very little idea about what each one does. One way of studying genes is to directly compare the entire genome with other organisms. This study is called comparative genomics. The human genome is extremely c ...
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Human genome



The human genome is the complete set of nucleic acid sequence for humans (Homo sapiens), encoded as DNA within the 23 chromosome pairs in cell nuclei and in a small DNA molecule found within individual mitochondria. Human genomes include both protein-coding DNA genes and noncoding DNA. Haploid human genomes, which are contained in germ cells (the egg and sperm gamete cells created in the meiosis phase of sexual reproduction before fertilization creates a zygote) consist of three billion DNA base pairs, while diploid genomes (found in somatic cells) have twice the DNA content. While there are significant differences among the genomes of human individuals (on the order of 0.1%), these are considerably smaller than the differences between humans and their closest living relatives, the chimpanzees (approximately 4%) and bonobos. Humans share 50% of their DNA with bananas.The Human Genome Project produced the first complete sequences of individual human genomes, with the first draft sequence and initial analysis being published on February 12, 2001. The human genome was the first of all vertebrates to be completely sequenced. As of 2012, thousands of human genomes have been completely sequenced, and many more have been mapped at lower levels of resolution. The resulting data are used worldwide in biomedical science, anthropology, forensics and other branches of science. There is a widely held expectation that genomic studies will lead to advances in the diagnosis and treatment of diseases, and to new insights in many fields of biology, including human evolution.Although the sequence of the human genome has been (almost) completely determined by DNA sequencing, it is not yet fully understood. Most (though probably not all) genes have been identified by a combination of high throughput experimental and bioinformatics approaches, yet much work still needs to be done to further elucidate the biological functions of their protein and RNA products. Recent results suggest that most of the vast quantities of noncoding DNA within the genome have associated biochemical activities, including regulation of gene expression, organization of chromosome architecture, and signals controlling epigenetic inheritance.There are an estimated 20,000-25,000 human protein-coding genes. The estimate of the number of human genes has been repeatedly revised down from initial predictions of 100,000 or more as genome sequence quality and gene finding methods have improved, and could continue to drop further. Protein-coding sequences account for only a very small fraction of the genome (approximately 1.5%), and the rest is associated with non-coding RNA molecules, regulatory DNA sequences, LINEs, SINEs, introns, and sequences for which as yet no function has been elucidated.
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