Shannon Looney – Schizophrenia and Bipolar
... trios of parents and children. Their results indicated that NRG1 seems to be strongly associated with Schizophrenia, and there was some evidence that it is also involved in susceptibility to Bipolar or manic disorder, although this evidence was weaker. NRG1 is thought (like DAOA) to be involved in s ...
... trios of parents and children. Their results indicated that NRG1 seems to be strongly associated with Schizophrenia, and there was some evidence that it is also involved in susceptibility to Bipolar or manic disorder, although this evidence was weaker. NRG1 is thought (like DAOA) to be involved in s ...
TCGA discovers potential therapeutic targets for lung squamous cell
... Researchers have identified potential therapeutic targets in lung squamous cell carcinoma, the second most common form of lung cancer. The Cancer Genome Atlas (TCGA) Research Network study that appeared online Sept. 9, 2012, and in print Sept. 27, 2012, in the journal Nature, comprehensively charact ...
... Researchers have identified potential therapeutic targets in lung squamous cell carcinoma, the second most common form of lung cancer. The Cancer Genome Atlas (TCGA) Research Network study that appeared online Sept. 9, 2012, and in print Sept. 27, 2012, in the journal Nature, comprehensively charact ...
Von Hippel-Lindau Disease - Birmingham Women`s Hospital
... the two doctors who described it. Although VHL disease can have serious complications, if these are detected early they can usually be ...
... the two doctors who described it. Although VHL disease can have serious complications, if these are detected early they can usually be ...
Some aspects of Androgenic alopecia treatment Gladko
... It always takes a long time to treat AGA and sometimes patients are not satisfied with the results. Until quite recently pathogenetic therapy was based on oral use of systematic antiandrogens, which have a plenty of side effects. The main are: potency and libido decrease in men, sensitivity shift of ...
... It always takes a long time to treat AGA and sometimes patients are not satisfied with the results. Until quite recently pathogenetic therapy was based on oral use of systematic antiandrogens, which have a plenty of side effects. The main are: potency and libido decrease in men, sensitivity shift of ...
Transgenic Animals - Lungeninformationsdienst
... 1981 – First transgenic mouse (Gordon and Ruddle) – first time the term transgenic occured 1982 - The ‘Supermouse’ produced by Brinster and Palmiter It was created by inserting a human growth hormone gene in mouse genome. The offspring was much larger than the parents. ...
... 1981 – First transgenic mouse (Gordon and Ruddle) – first time the term transgenic occured 1982 - The ‘Supermouse’ produced by Brinster and Palmiter It was created by inserting a human growth hormone gene in mouse genome. The offspring was much larger than the parents. ...
Leukaemia Section t(1;21)(p22;q22) RUNX1/CLCA2 Atlas of Genetics and Cytogenetics
... second bone marrow transplantation. The adult patient was treated with a standard induction chemotherapy regimen (infusional cytarabine combined with daunorubicine) and two cycles of consolidation therapy with high doses cytarabine, followed by a reduced intensity allogeneic stem cell transplantatio ...
... second bone marrow transplantation. The adult patient was treated with a standard induction chemotherapy regimen (infusional cytarabine combined with daunorubicine) and two cycles of consolidation therapy with high doses cytarabine, followed by a reduced intensity allogeneic stem cell transplantatio ...
Pennisi E
... modules have been added or lost. That understanding, in turn, is changing how some researchers make sense of evolution, adds Michael Ludwig of the University of Chicago. It's a vision in which regulatory elements, including enhancers and silencers, are as important, if not more important, than gene ...
... modules have been added or lost. That understanding, in turn, is changing how some researchers make sense of evolution, adds Michael Ludwig of the University of Chicago. It's a vision in which regulatory elements, including enhancers and silencers, are as important, if not more important, than gene ...
Exam 1 (Instructor, Fall 2012)
... Using pressure and suction, the media but not cells were passed from one side of the fine filter to the other. Following this media exchange, strain A- and B- cells were taken and plated on minimal medium and some colonies developed. From this result, it can be concluded that the original growth on ...
... Using pressure and suction, the media but not cells were passed from one side of the fine filter to the other. Following this media exchange, strain A- and B- cells were taken and plated on minimal medium and some colonies developed. From this result, it can be concluded that the original growth on ...
video slide - Biology Junction
... expressing the recessive trait (white flowers in this example). By observing the phenotypes of the offspring resulting from this cross, we can deduce the genotype of the purple-flowered parent. ...
... expressing the recessive trait (white flowers in this example). By observing the phenotypes of the offspring resulting from this cross, we can deduce the genotype of the purple-flowered parent. ...
Genetics Unit
... • 3) in the F1 generation, the tall factor was dominant (factor that is seen) • 4) In the F2 generation, the short factor or (t) produced 1 short plant So short is recessive (factor not seen) ...
... • 3) in the F1 generation, the tall factor was dominant (factor that is seen) • 4) In the F2 generation, the short factor or (t) produced 1 short plant So short is recessive (factor not seen) ...
Brooker Chapter 17
... Retroviruses - RNA viruses that make a DNA copy that integrates into the host’s genome ...
... Retroviruses - RNA viruses that make a DNA copy that integrates into the host’s genome ...
genetic sleuths unmask secrets of big tomatoes
... A true wild tomato may have only two to four of these. "Somehow, something made the plant start making these compartments, and by making more compartments, you can get larger fruit." GENE TROLL To understand this process, Tanksley first mapped the tomato's roughly 30,000 genes, looking for differenc ...
... A true wild tomato may have only two to four of these. "Somehow, something made the plant start making these compartments, and by making more compartments, you can get larger fruit." GENE TROLL To understand this process, Tanksley first mapped the tomato's roughly 30,000 genes, looking for differenc ...
Supplemental Digital Content
... Patients were seen every 2-4 weeks for 6 months, then every 4-6 weeks for 6 months, then every 6-8 weeks in the second year, then every 8-12 weeks. At each follow-up visits clinical events were recorded, and the levels of alanine aminotransferase (ALT), HBV DNA, and serum creatinine were measured. C ...
... Patients were seen every 2-4 weeks for 6 months, then every 4-6 weeks for 6 months, then every 6-8 weeks in the second year, then every 8-12 weeks. At each follow-up visits clinical events were recorded, and the levels of alanine aminotransferase (ALT), HBV DNA, and serum creatinine were measured. C ...
DOCX format - 66 KB - Office of the Gene Technology Regulator
... Both the short and long term were considered. Credible pathways to potential harm that were considered included exposure of people or other organisms through contact with or ingestion of GM carnation flowers and spread and persistence of GM plants or hybrid offspring leading to increased toxicity or ...
... Both the short and long term were considered. Credible pathways to potential harm that were considered included exposure of people or other organisms through contact with or ingestion of GM carnation flowers and spread and persistence of GM plants or hybrid offspring leading to increased toxicity or ...
Kidneys and Hypertension
... 31% of Americans have BP > 140/90 mmHg Most patients asymptomatic Single most preventable cause of premature death in developed countries. ...
... 31% of Americans have BP > 140/90 mmHg Most patients asymptomatic Single most preventable cause of premature death in developed countries. ...
Gregor Mendel, 1822-1884
... she wants to use for breeding purposes if possible. The dog can hear, so the owner knows his genotype is either DD or Dd. If the dog’s genotype is Dd, the owner does not wish to use him for breeding so that the deafness gene will not be passed on. This can be tested by breeding the dog to a deaf fem ...
... she wants to use for breeding purposes if possible. The dog can hear, so the owner knows his genotype is either DD or Dd. If the dog’s genotype is Dd, the owner does not wish to use him for breeding so that the deafness gene will not be passed on. This can be tested by breeding the dog to a deaf fem ...
Primordial Germ Cells
... For nearly a century, scientists have firmly believed that whereas men can produce sperm throughout their lives, women are born with all the eggs they will ever have. But new research suggests that this basic tenet of reproductive biology is wrong, a discovery that could have enormous repercussions ...
... For nearly a century, scientists have firmly believed that whereas men can produce sperm throughout their lives, women are born with all the eggs they will ever have. But new research suggests that this basic tenet of reproductive biology is wrong, a discovery that could have enormous repercussions ...
Gene therapy
Gene therapy is the therapeutic delivery of nucleic acid polymers into a patient's cells as a drug to treat disease. Gene therapy could be a way to fix a genetic problem at its source. The polymers are either expressed as proteins, interfere with protein expression, or possibly correct genetic mutations.The most common form uses DNA that encodes a functional, therapeutic gene to replace a mutated gene. The polymer molecule is packaged within a ""vector"", which carries the molecule inside cells.Gene therapy was conceptualized in 1972, by authors who urged caution before commencing human gene therapy studies. By the late 1980s the technology had already been extensively used on animals, and the first genetic modification of a living human occurred on a trial basis in May 1989 , and the first gene therapy experiment approved by the US Food and Drug Administration (FDA) occurred on September 14, 1990, when Ashanti DeSilva was treated for ADA-SCID. By January 2014, some 2,000 clinical trials had been conducted or approved.Early clinical failures led to dismissals of gene therapy. Clinical successes since 2006 regained researchers' attention, although as of 2014, it was still largely an experimental technique. These include treatment of retinal disease Leber's congenital amaurosis, X-linked SCID, ADA-SCID, adrenoleukodystrophy, chronic lymphocytic leukemia (CLL), acute lymphocytic leukemia (ALL), multiple myeloma, haemophilia and Parkinson's disease. Between 2013 and April 2014, US companies invested over $600 million in the field.The first commercial gene therapy, Gendicine, was approved in China in 2003 for the treatment of certain cancers. In 2011 Neovasculgen was registered in Russia as the first-in-class gene-therapy drug for treatment of peripheral artery disease, including critical limb ischemia.In 2012 Glybera, a treatment for a rare inherited disorder, became the first treatment to be approved for clinical use in either Europe or the United States after its endorsement by the European Commission.