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Text S1.
Text S1.

... positive and negative pairs together construct the gold standard set which is later used for integrating the posteriors derived from all datasets. Second, we transformed each input dataset into gene-gene pair-wise values that represent the similarity between genes. These values were later used to es ...
Metabolism
Metabolism

... website, textbook has errors. ...
THE NORMAL METABOLISM OF PHENYLALANINE (pathways a
THE NORMAL METABOLISM OF PHENYLALANINE (pathways a

Guidelines for Genome Annotation - Muktak
Guidelines for Genome Annotation - Muktak

... predictions of genes (by the automated annotation at Oak Ridge National Laboratories (ORNL) of the Joint Genome Institute (JGI), and by our collaborator Julia Krushkal) that may not agree. I want to get rid of as many incorrect gene predictions as possible. Each predicted gene has its own page, wher ...
Laboratory 9 Protein assay
Laboratory 9 Protein assay

... 7. Carefully reposition the tubes in the microcentrifuge as before, with the cap-hinge and pellet facing outward. Centrifuge the tubes again to bring any remaining liquid to the bottom of the tube. A brief pulse is sufficient. Use a micropipette to remove the remaining supernatant. There should be n ...
Protein Determination - International Dairy Federation
Protein Determination - International Dairy Federation

... intact proteins based on their physical properties such as size, electrical charge or hydrophobic/hydrophilic properties and then measuring the relative amounts of each. There are several different types of chromatography methods available such as size-exclusion chromatography, ion-exchange chromato ...
Proteins 101 - Virginia Tech
Proteins 101 - Virginia Tech

... // “Gold standard”. Atomic resolution. // Crystal packing artefacts, not all proteins can be crystallized well, problems with large ones, membrane proteins, missing hydrogens, and, sometimes, big chunks of structure •NMR // “true” structure in solution. Can get hydrogens. Can trace some dynamics (e. ...
Polymer mediated (PM) interactions between colloidal particles are
Polymer mediated (PM) interactions between colloidal particles are

... Polymer mediated (PM) interactions between colloidal particles are in the core of many biologically and technologically relevant phenomena such as red blood cell adhesion, DNA mediated depletion interactions and size-exclusion polymer chromatography. In our group, we study PM interactions by develop ...
E. Coli
E. Coli

... B. Heat Stress Proteome during Sporulation 60 stress proteins were synthesized de novo and/or overexpressed in B. subtilis during sporulation concurrent to acquired thermotolerance in spores. ...
(Conjugated) Proteins in the SPC
(Conjugated) Proteins in the SPC

... < type of protein> is conjugated with at a degree of substitution of . The average molecular mass is approximately of which the protein moiety constitutes approximately . This may be followed by a description of isof ...
Lect 9: BioMacromolecular Visualization I: Principles - BIDD
Lect 9: BioMacromolecular Visualization I: Principles - BIDD

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Examples of Biomaterials

... between end-grafted polymers is less than twice the Flory radius, RF, where RF ~ aN3/5 and a is the monomer size ...
Protein C Deficiency info sheet
Protein C Deficiency info sheet

... If both Protein C genes are abnormal the patient is homozygous and one copy of the abnormal gene will be passed on to all their children. This is associated with a significant risk of thrombosis and presents at birth or soon after. ...
slides
slides

... essential scaffold that gives the surface its contours and chemical properties. • These areas are often the secondary structures and domains of the protein, that give it its 3dimensional shape – beta-sheets and alpha-helices. • Therefore, mistakes in the amino acids in these domains can change the 3 ...


... 2. Ho - Van der Waals forces. This is unfavorable for unfolding. Van der Waals interactions are more stable in the native form of the protein. ...
Glucose/Galactose Binding Protein (GGBP)
Glucose/Galactose Binding Protein (GGBP)

GPSDB: a new database for synonyms expan
GPSDB: a new database for synonyms expan

... INTRODUCTION Although guidelines exist for naming gene and protein entities, many authors describe the latter in scientific texts using their own term. Furthermore, before such nomenclatures existed, authors could freely choose the names for the genes and proteins they were studying. As a result the ...
Physical Chemistry, Short talk PC-013 Protein
Physical Chemistry, Short talk PC-013 Protein

... In this contribution we present strategies to characterize protein-nucleotide interactions in large biological assemblies using the example of the (double-) hexameric DnaB helicase from Helicobacter pylori with a molecular weight of 672 kDa. The binding of nucleotides (ATP-analogues and single-stran ...
Biochemistry-lab-identifying
Biochemistry-lab-identifying

... the individual Lego bricks that fit together to build a bigger structure. Therefore, amino acids are often called the “building blocks of protein.” There are more than 20 different amino acids. The suffixes -in, -ine identify a protein, amino acid or nucleic acid. Examples: vitamin, pepsin, insulin, ...
No Slide Title
No Slide Title

... The Principle of Additivity Consider the double mutant, AB, composed of mutation A and mutation B. In general (but not always -- see below), the binding free energy perturbations caused by single mutations are additive, in other words DDG°wt-mutAB = DDG°wt-mutA + DDG°wt-mutB + DDG°i where DDG°i ...
1 Which of structures below stands for D
1 Which of structures below stands for D

protein modelling
protein modelling

... Select the best template(min.30%) from a library of known protein structures derived from the PDB. ...
Intro to Bioinformatics
Intro to Bioinformatics

steroid hormone-97
steroid hormone-97

... Androgen insensitivity - an inherited condition in mammals where XY individual fails to develop male sex characteristics - due to: Tfm syndrome- lack of testosterone receptor protein genotype is: Tfm ...
L2_Protein Structure_12_Jan
L2_Protein Structure_12_Jan

... L-α-amino acid • Thershold number of peptide bond to perform biochemical function by protein : >40. • Correlation between mRNA and protein: – Protein synthesis from mRNA – mRNA degradation can takes place after protein formation and still protein will exist – Ribosomes are the cell’s protein functio ...
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Interactome



In molecular biology, an interactome is the whole set of molecular interactions in a particular cell. The term specifically refers to physical interactions among molecules (such as those among proteins, also known as protein-protein interactions) but can also describe sets of indirect interactions among genes (genetic interactions). Mathematically, interactomes are generally displayed as graphs.The word ""interactome"" was originally coined in 1999 by a group of French scientists headed by Bernard Jacq. Though interactomes may be described as biological networks, they should not be confused with other networks such as neural networks or food webs.
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