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Thyroid autoimmunity - Journal of Clinical Investigation
... to inhibit the binding to TPO of most TPO autoantibodies in an individual patient’s serum, indicates that these epitopes comprise the immunodominant region of the protein. Quantitative competition studies with these four recombinant autoantibody Fab’s have also been used to characterize the polyclon ...
... to inhibit the binding to TPO of most TPO autoantibodies in an individual patient’s serum, indicates that these epitopes comprise the immunodominant region of the protein. Quantitative competition studies with these four recombinant autoantibody Fab’s have also been used to characterize the polyclon ...
Session 417 Clinical microbiology
... Icahn School of Medicine at Mount Sinai, New York, NY. Purpose: Staphylococci are common causative pathogens in ophthalmic infections, with numerous studies demonstrating significant antibiotic resistance among these bacteria. The Antibiotic Resistance in Ocular MicrooRganisms (ARMOR) study is a nat ...
... Icahn School of Medicine at Mount Sinai, New York, NY. Purpose: Staphylococci are common causative pathogens in ophthalmic infections, with numerous studies demonstrating significant antibiotic resistance among these bacteria. The Antibiotic Resistance in Ocular MicrooRganisms (ARMOR) study is a nat ...
AMOXIL (amoxicillin capsules, tablets, chewable tablets, and powder for oral suspension)
... AMOXIL has been partially investigated. The 400-mg and 875-mg formulations have been studied only when administered at the start of a light meal. However, food effect studies have not been performed with the 200-mg and 500-mg formulations. Amoxicillin diffuses readily into most body tissues and flui ...
... AMOXIL has been partially investigated. The 400-mg and 875-mg formulations have been studied only when administered at the start of a light meal. However, food effect studies have not been performed with the 200-mg and 500-mg formulations. Amoxicillin diffuses readily into most body tissues and flui ...
PDF (all abstracts) - Allergy, Asthma & Clinical Immunology
... Background: Capturing symptom data for large studies (≥60 participants) in ≤30 minutes is hard to achieve using manual data entry without substantial costs and resources. This challenge is highlighted if the data are needed to make real-time clinical decisions. The 140 participant capacity of the En ...
... Background: Capturing symptom data for large studies (≥60 participants) in ≤30 minutes is hard to achieve using manual data entry without substantial costs and resources. This challenge is highlighted if the data are needed to make real-time clinical decisions. The 140 participant capacity of the En ...
Atopic Dermatitis
... regulating the epidermal homeostasis, the epidermal differentiation complex (EDC). The recent demonstration of loss-of-function mutations of the profilaggrin/filaggrin gene, a key protein in terminal differentiation of the epidermis, can be considered as a breakthrough8-13. Indeed, these variations ...
... regulating the epidermal homeostasis, the epidermal differentiation complex (EDC). The recent demonstration of loss-of-function mutations of the profilaggrin/filaggrin gene, a key protein in terminal differentiation of the epidermis, can be considered as a breakthrough8-13. Indeed, these variations ...
AFA 11th Edition TEXT_FINAL sequence.indd
... enzyme-linked immunosorbent assay, or ELISA. Screening ELISAs include a test for P24 antigen, which enables early diagnosis of HIV before antibodies are produced. Although the HIV ELISA has 100% sensitivity (no false negatives – but see notes on the “window period” below) it has a specificity of 99.7 ...
... enzyme-linked immunosorbent assay, or ELISA. Screening ELISAs include a test for P24 antigen, which enables early diagnosis of HIV before antibodies are produced. Although the HIV ELISA has 100% sensitivity (no false negatives – but see notes on the “window period” below) it has a specificity of 99.7 ...
Sputum colour and bacteria in chronic bronchitis exacerbations: a pooled analysis
... disease was the observation that not all three criteria had the same predictive value. STOCKLEY et al. [3], with the aid of a colour chart, demonstrated that a change in sputum colour during the course of an exacerbation was a sensitive and specific marker for bacterial presence and was also predict ...
... disease was the observation that not all three criteria had the same predictive value. STOCKLEY et al. [3], with the aid of a colour chart, demonstrated that a change in sputum colour during the course of an exacerbation was a sensitive and specific marker for bacterial presence and was also predict ...
Erbitux 5 mg/mL
... effector cells. Therefore, in addition to its inhibitory function on receptor signalling, patients with EGFR-expressing tumours may also benefit from this immune stimulatory effect of cetuximab. Immunogenicity The development of human anti-chimaeric antibodies (HACA) is a class-specific effect of mo ...
... effector cells. Therefore, in addition to its inhibitory function on receptor signalling, patients with EGFR-expressing tumours may also benefit from this immune stimulatory effect of cetuximab. Immunogenicity The development of human anti-chimaeric antibodies (HACA) is a class-specific effect of mo ...
A COMPARATIVE CLINICAL TRIAL OF ALBENDAZOLE VERSUS
... Six children on metronidazole therapy, who were not anorexic prior to the treatment, developed loss of appetite after 2 to 4 days of treatment. No side effects were reported in children treated with albendazole. The absence of any significant difference in the hematological and biochemical parameter ...
... Six children on metronidazole therapy, who were not anorexic prior to the treatment, developed loss of appetite after 2 to 4 days of treatment. No side effects were reported in children treated with albendazole. The absence of any significant difference in the hematological and biochemical parameter ...
Guidelines for the Management of Vitiligo The European Dermatology Forum Consensus
... those treated with PUVA. Accordingly, NB-UVB was superior to oral PUVA, and most treatment centres currently consider NB-UVB as the first-line treatment for NSV.[38] Moreover, 5-MOP is currently unavailable, further limiting the use of PUVA therapy. Only a few long-term follow-up studies have invest ...
... those treated with PUVA. Accordingly, NB-UVB was superior to oral PUVA, and most treatment centres currently consider NB-UVB as the first-line treatment for NSV.[38] Moreover, 5-MOP is currently unavailable, further limiting the use of PUVA therapy. Only a few long-term follow-up studies have invest ...
Acute Kidney Injury Best Practice Guidance: Responding to AKI
... National Confidential Enquiry into Patient Outcome and Death (NCEPOD) report into sepsis ...
... National Confidential Enquiry into Patient Outcome and Death (NCEPOD) report into sepsis ...
CLINICAL VIGNETTE ABSTRACTS Poster Session I Thursday, October 23, 2104
... and hypoalbuminemia. Discussion: EGID is a rare disorder with less than 300 adult and pediatric cases reported. It is characterized by increased numbers of eosinophils throughout the GI tract. Diagnosis is made based on histological evaluation. Symptoms are usually nonspecific but always include som ...
... and hypoalbuminemia. Discussion: EGID is a rare disorder with less than 300 adult and pediatric cases reported. It is characterized by increased numbers of eosinophils throughout the GI tract. Diagnosis is made based on histological evaluation. Symptoms are usually nonspecific but always include som ...
Discovering potential drug-targets for personalized treatment of
... potential therapeutic targets that interfere in different phases of disease progression. Therapeutic interventions acting upon these candidate drug targets in animal models of EBA, such as cytokine-modulating biologics and small molecules, have validated them as potential new therapeutic strategies ...
... potential therapeutic targets that interfere in different phases of disease progression. Therapeutic interventions acting upon these candidate drug targets in animal models of EBA, such as cytokine-modulating biologics and small molecules, have validated them as potential new therapeutic strategies ...
report - Fuller Treacy Money
... estimates that pharmaceutical R&D spending has increased more than twenty-fold over the past 30 years. As a consequence, more molecules than ever before are entering research pipelines (although failure rates have also risen substantially, as we discuss later). The number of compounds in clinical tr ...
... estimates that pharmaceutical R&D spending has increased more than twenty-fold over the past 30 years. As a consequence, more molecules than ever before are entering research pipelines (although failure rates have also risen substantially, as we discuss later). The number of compounds in clinical tr ...
J A S H
... damage; in our experience, this payment is typically less than the true cost of the procedure. Other insurers are becoming more liberal in reimbursing for ABPM but prior authorization is the rule rather than the exception. Self-monitoring (home) BP devices have undergone substantial changes during t ...
... damage; in our experience, this payment is typically less than the true cost of the procedure. Other insurers are becoming more liberal in reimbursing for ABPM but prior authorization is the rule rather than the exception. Self-monitoring (home) BP devices have undergone substantial changes during t ...
MYCOBACTERIUM AVIUM PARATUBERCULOSIS: Infrequent Human Pathogen or Public Health Threat?
... diagnostics that can detect early MAP infection, knowledge of how and where to isolate MAP for antibiotic susceptibility studies, and drugs that are known to be active against MAP itself, alone or in combination, the role of MAP in CD will remain circumstantial and the controversy over CD etiology w ...
... diagnostics that can detect early MAP infection, knowledge of how and where to isolate MAP for antibiotic susceptibility studies, and drugs that are known to be active against MAP itself, alone or in combination, the role of MAP in CD will remain circumstantial and the controversy over CD etiology w ...
European Pharmaceuticals
... estimates that pharmaceutical R&D spending has increased more than twenty-fold over the past 30 years. As a consequence, more molecules than ever before are entering research pipelines (although failure rates have also risen substantially, as we discuss later). The number of compounds in clinical tr ...
... estimates that pharmaceutical R&D spending has increased more than twenty-fold over the past 30 years. As a consequence, more molecules than ever before are entering research pipelines (although failure rates have also risen substantially, as we discuss later). The number of compounds in clinical tr ...
UCD Medicine Research - University College Dublin
... to specifically target drugs against reverse transcriptase in Hepatitis B. “This is like kicking open the barn door,” he says. “There has never been a focused drug discovery programme targeting the viral RT from Hepatitis B, but now this is possible.” New perspectives Dr Ferguson’s findings about He ...
... to specifically target drugs against reverse transcriptase in Hepatitis B. “This is like kicking open the barn door,” he says. “There has never been a focused drug discovery programme targeting the viral RT from Hepatitis B, but now this is possible.” New perspectives Dr Ferguson’s findings about He ...
blocking agents and interleukin-1 - Annals of the Rheumatic Diseases
... use of biological agents was constituted by rheumatologists from the universities of Erlangen, Leiden, and Vienna in Europe in cooperation with other universities in the USA, Canada, and Europe. Pharmaceutical industry support was obtained from a number of companies, but these institutions had no pa ...
... use of biological agents was constituted by rheumatologists from the universities of Erlangen, Leiden, and Vienna in Europe in cooperation with other universities in the USA, Canada, and Europe. Pharmaceutical industry support was obtained from a number of companies, but these institutions had no pa ...
BOLETíN MÉDICO del HOSPITAL INFANTIL de MÉXICO
... the strong relationship with metabolic and cardiovascular diseases, there is interest in understanding the mechanisms conducive to obesity as well as the mechanisms that triggers its consequences. Genetic and environmental factors deserve the most attention. With respect to genetic factors, >400 gen ...
... the strong relationship with metabolic and cardiovascular diseases, there is interest in understanding the mechanisms conducive to obesity as well as the mechanisms that triggers its consequences. Genetic and environmental factors deserve the most attention. With respect to genetic factors, >400 gen ...
Management of Tuberculosis - Kementerian Kesihatan Malaysia
... for another ten years. In addition, the reference lists of all retrieved literature and guidelines were searched to further identify relevant studies. Experts in the field were also contacted to identify further studies. All searches were conducted between 9 May 2011 - 29 March 2012. Literature sear ...
... for another ten years. In addition, the reference lists of all retrieved literature and guidelines were searched to further identify relevant studies. Experts in the field were also contacted to identify further studies. All searches were conducted between 9 May 2011 - 29 March 2012. Literature sear ...
Genetic and phenotypic variation of the equine infectious anemia
... propagation of the genome by the cell. In addition, RNA viruses, such as lentiviruses, typically maintain chronic, low levels of virus replication. On the other hand, DNA viruses more effectively establish latency because the host cell performs processes that help maintain the genome in a quiescent ...
... propagation of the genome by the cell. In addition, RNA viruses, such as lentiviruses, typically maintain chronic, low levels of virus replication. On the other hand, DNA viruses more effectively establish latency because the host cell performs processes that help maintain the genome in a quiescent ...