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Bullous Pemphigoid Updated
Bullous Pemphigoid Updated

... MK is at risk for infections secondary to open blisters as a result of his bullous pemphigoid and would benefit from a reassessment of his bullous pemphigoid treatment MK is experiencing continued pruritus secondary to his bullous pemphigoid and would benefit from a reassessment of his bullous pemph ...
(lymphocytic) - bendamustine: Evidence Review Group report
(lymphocytic) - bendamustine: Evidence Review Group report

... Of the 319 participants recruited, 162 were randomised to bendamustine and 157 patients randomised to chlorambucil. Patients‟ response to the treatment was assessed according to criteria defined by the National Cancer Institute Working Group on CLL2 3 and had to be met for at least eight weeks. Aft ...
Infectivity of Severe Acute Respiratory Syndrome during Its
Infectivity of Severe Acute Respiratory Syndrome during Its

... Objective  To  evaluate  the  infectivity  of  severe  acute  respiratory  syndrome  (SARS)  during  its  incubation  period  by  investigating  chains  of  transmission  and  individuals  isolated  for  medical  observation  with  a  view  to  providing  scientific  evidence  for  updating  protoco ...
MabThera : EPAR - Product Information - EMA
MabThera : EPAR - Product Information - EMA

... untreated and relapsed/refractory CLL. Only limited data are available on efficacy and safety for patients previously treated with monoclonal antibodies including MabThera or patients refractory to previous MabThera plus chemotherapy. ...
Lupus and Kidney Inflammation
Lupus and Kidney Inflammation

... Unfortunately, studies show that around 50% of our patients with lupus do not take their hydroxychloroquine regularly which is a shame. Taking these facts into account, I would state that three of the most important things for lupus patients to do in order to decrease their risk of getting lupus nep ...
VASF Guide to Antimicrobials 2015
VASF Guide to Antimicrobials 2015

... norfloxacin 400 mg/day reduced the 6-month probability of developing SBP from 9% to 0%, but the risk of gram-negative bacillary SBP was not significantly reduced. Ciprofloxacin 750 mg once weekly reduced the 6-month probability of developing SBP from 22% to 3.6% in patients with low ascitic fluid p ...
Nova Scotia Formulary Updates
Nova Scotia Formulary Updates

... with family or friends, or living in a supportive living residence, but does not include a hospital setting or a palliative care unit Once patients are approved for coverage, a nurse or physician from the DHA/IWK Palliative Care Team will complete a Medication Authorization Form and forward to the c ...
Payers SOF+Simeprevir
Payers SOF+Simeprevir

Comparison of Hypertonic Saline to Epinephrine in
Comparison of Hypertonic Saline to Epinephrine in

... It is postulated that nebulised hypertonic saline may be beneficial in bronchiolitis also. Cochrane database analysis, involving 4 trials with 254 infants, using hypertonic saline mixed with bronchodilators, suggests nebulised 3% saline may significantly reduce the length of hospital stay and improv ...
Phenotype and genotype in 101 males with X-linked creatine transporter deficiency.
Phenotype and genotype in 101 males with X-linked creatine transporter deficiency.

Triggers and treatment of rosacea
Triggers and treatment of rosacea

... Topical metronidazole 0.5 to 0.75% (available as a cream or gel) applied once or twice daily is effective in treating patients with papulopustular rosacea and has been used since the 1980s. It may also reduce blanchable erythema (but not telangiectasia) in patients with erythematotelangiectatic rosa ...
clinical review - Blogs @ Butler
clinical review - Blogs @ Butler

... keep TSH within the desired range. It is important to recognize factors that may interfere with the ability to maintain a desired TSH concentration. Food can diminish the absorption by 40% to 64%.46 It is recommended that levothyroxine be administered while fasting, usually one hour before meals. Re ...
Differentiating Difficult to Control vs. Severe Asthma Disclosures
Differentiating Difficult to Control vs. Severe Asthma Disclosures

... • Quick-Relief Medication for All Patients: • SABA as needed for symptoms. Intensity of treatment depends on severity of symptoms: up to 3 treatments at 20-minute intervals as needed. Short course of systemic oral corticosteroids may be needed. • Caution: Increasing of beta-agonist or use >2x/week f ...
Reducing Uveitic Glaucoma: therapeutic judgement is the key
Reducing Uveitic Glaucoma: therapeutic judgement is the key

... over five years. Most studies found UG equally distributed among anterior and posterior uveitis.70% of UG in our study is associated with anterior uveitis which is also the case in single centre study in US [9].This can be explained by associated cases of ankylosing spondylitis, herpetic eye disease ...
Prescribing Information - PI
Prescribing Information - PI

... LABA, such as formoterol, one of the active ingredients in SYMBICORT, increase the risk of asthma-related death. Currently available data are inadequate to determine whether concurrent use of inhaled corticosteroids or other long-term asthma control drugs mitigates the increased risk of asthma-relat ...
A W LLERGY ATCH
A W LLERGY ATCH

The Management of Primary Aldosteronism: Case Detection
The Management of Primary Aldosteronism: Case Detection

... Figure 1. Algorithm for the detection, confirmation, subtype testing, and treatment of PA. a We recommend unilateral laparoscopic adrenalectomy for patients with documented unilateral PA (ie, APA or UAH) (1⎪QQQE). If a patient is unable or unwilling to undergo surgery, we recommend medical treatment ...
Lyme Disease? - Nutri-Spec
Lyme Disease? - Nutri-Spec

... that claim with no objective evidence backing up their stance. In patient after patient, they insist that the patient has Lyme Disease despite no antibodies, and they base their diagnosis entirely on symptoms and other criteria that are not at all specific for Lyme. These Lyme specialists are treati ...
Guideline - Heart Foundation
Guideline - Heart Foundation

... HF is a complex clinical syndrome occurring as the end result of a variety of different forms of heart disease. There are many different definitions and classifications of HF but a simple, practical definition of the syndrome of HF is that it is characterised by typical symptoms such as shortness of ...
An approach to paediatric asthma: the role of the community pharmacist ReView
An approach to paediatric asthma: the role of the community pharmacist ReView

... Asthma is one of the most common chronic childhood illnesses, and affects up to 20% of South African children.1 According to the International Study on Asthma and Allergies in Childhood (ISAAC), the prevalence of allergic diseases, including asthma, is rising, particularly in the developing world.2 ...
intravenous dexamethasone as post operative
intravenous dexamethasone as post operative

... troublesome in day surgery. At the very least the patient experience discomfort, but persistent symptoms causing a delay in returning to normal activities for greater than one day has been reported(9). Nausea and vomiting may delay discharge from the recovery room tying up human and material resourc ...
The treatment challenges of restless legs syndrome
The treatment challenges of restless legs syndrome

... with medications.17. Dopamine agonists are the first-line treatment for RLS. In the UK, immediate-release (pramipexole and ropinirole) and transdermal (rotigotine) preparations are the only dopamine agonists licensed for treatment of RLS (see Table 3). However, prolonged-release pramipexole and ro ...
Why does the rapid delivery of drugs to the brain promote addiction?
Why does the rapid delivery of drugs to the brain promote addiction?

... occupancy, smoked cocaine leads to greater self-reports of a ‘high’ than does intranasally administered cocaine [47]. The influence of the rate of intravenous cocaine administration (5–100 s) on the half-life of electrically evoked DA release in the nucleus accumbens core was examined recently in ra ...
CORE MODULES & FORMS OF TOBACCO
CORE MODULES & FORMS OF TOBACCO

... Nicotine in cartridges is depleted after about 20 minutes of active puffing ...
Initiative of Central TB Division Ministry of Health and Family Welfare
Initiative of Central TB Division Ministry of Health and Family Welfare

... scriptures, that Soma, the Moon God himself, suffered from an ailment indistinguishable to the disease we now call “tuberculosis”. Indeed, this scourge has afflicted mankind through the millennia, not sparing anyone; be it the poor or the rich, the common man or the ruler. The global burden of tuber ...
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Management of multiple sclerosis



Several therapies for multiple sclerosis (MS) exist, although there is no known cure. Multiple sclerosis is a chronic inflammatory demyelinating disease that affects the central nervous system (CNS).The most common initial course of the disease is the relapsing-remitting subtype, which is characterized by unpredictable attacks (relapses) followed by periods of relative remission with no new signs of disease activity. After some years, many of the people who have this subtype begin to experience neurologic decline without acute relapses. When this happens it is called secondary progressive multiple sclerosis. Other, less common, courses of the disease are the primary progressive (decline from the beginning without attacks) and the progressive-relapsing (steady neurologic decline and superimposed attacks). Different therapies are used for patients experiencing acute attacks, for patients who have the relapsing-remitting subtype, for patients who have the progressive subtypes, for patients without a diagnosis of MS who have a demyelinating event, and for managing the various consequences of MS.The primary aims of therapy are returning function after an attack, preventing new attacks, and preventing disability. As with any medical treatment, medications used in the management of MS may have several adverse effects, and many possible therapies are still under investigation. At the same time different alternative treatments are pursued by many patients, despite the paucity of supporting, comparable, replicated scientific study.This article focuses on therapies for standard MS; borderline forms of MS have particular treatments that are excluded.
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