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Serum levels of lithium in patients of a psychiatric center in Manaus
Serum levels of lithium in patients of a psychiatric center in Manaus

... Another important fact is that some patients present signs of lithium toxicity after long periods of taking the same dose (Kehoe & Mender, 1992) that is why it is important to implement therapeutic monitoring in patients submitted to this medication therapy. The purpose of this article, part of a st ...
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Continuous intravenous epoprostenol for chronic thromboembolic pulmonary hypertension

... The effects of epoprostenol on the haemodynamic parameters observed in the present patients, in particular the increase in cardiac output, were similar to those in patients with PPH. In clinical studies of PPH [5, 6, 15], epoprostenol treatment tends to increase cardiac output more than it lowers PA ...
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Management of multiple sclerosis



Several therapies for multiple sclerosis (MS) exist, although there is no known cure. Multiple sclerosis is a chronic inflammatory demyelinating disease that affects the central nervous system (CNS).The most common initial course of the disease is the relapsing-remitting subtype, which is characterized by unpredictable attacks (relapses) followed by periods of relative remission with no new signs of disease activity. After some years, many of the people who have this subtype begin to experience neurologic decline without acute relapses. When this happens it is called secondary progressive multiple sclerosis. Other, less common, courses of the disease are the primary progressive (decline from the beginning without attacks) and the progressive-relapsing (steady neurologic decline and superimposed attacks). Different therapies are used for patients experiencing acute attacks, for patients who have the relapsing-remitting subtype, for patients who have the progressive subtypes, for patients without a diagnosis of MS who have a demyelinating event, and for managing the various consequences of MS.The primary aims of therapy are returning function after an attack, preventing new attacks, and preventing disability. As with any medical treatment, medications used in the management of MS may have several adverse effects, and many possible therapies are still under investigation. At the same time different alternative treatments are pursued by many patients, despite the paucity of supporting, comparable, replicated scientific study.This article focuses on therapies for standard MS; borderline forms of MS have particular treatments that are excluded.
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