DARZALEX ® - Prescribing Information
... dose of an intermediate acting or long-acting corticosteroid in accordance with local standards) on each of the 2 days following all DARZALEX infusions (beginning the day after the infusion). Combination therapy: Consider administering low-dose oral methylprednisolone (≤ 20 mg) or equivalent, the da ...
... dose of an intermediate acting or long-acting corticosteroid in accordance with local standards) on each of the 2 days following all DARZALEX infusions (beginning the day after the infusion). Combination therapy: Consider administering low-dose oral methylprednisolone (≤ 20 mg) or equivalent, the da ...
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... (suicidality) or unusual changes in behavior, whether or not they are taking these medications, and this risk may persist until significant remission occurs. Suicide is a known risk of depression and certain other psychiatric disorders, and these disorders themselves are the strongest predictors of ...
... (suicidality) or unusual changes in behavior, whether or not they are taking these medications, and this risk may persist until significant remission occurs. Suicide is a known risk of depression and certain other psychiatric disorders, and these disorders themselves are the strongest predictors of ...
DARZALEX Prescribing Information
... dose of an intermediate acting or long-acting corticosteroid in accordance with local standards) on each of the 2 days following all DARZALEX infusions (beginning the day after the infusion). Combination therapy: Consider administering low-dose oral methylprednisolone (≤ 20 mg) or equivalent, the da ...
... dose of an intermediate acting or long-acting corticosteroid in accordance with local standards) on each of the 2 days following all DARZALEX infusions (beginning the day after the infusion). Combination therapy: Consider administering low-dose oral methylprednisolone (≤ 20 mg) or equivalent, the da ...
Poster presentation
... Yeboah-Antwi et al (2001) showed that prepackaging of unit doses anti-malarial drugs not only improved adherence, but also reduced cost and waiting time by 50% Very few trials have been conducted in developing countries. ...
... Yeboah-Antwi et al (2001) showed that prepackaging of unit doses anti-malarial drugs not only improved adherence, but also reduced cost and waiting time by 50% Very few trials have been conducted in developing countries. ...
Diagnosis and Management of Acute Myelopathies
... Review Summary: In this article, we summarize recent classification and diagnostic schemes, which provide a framework for the diagnosis and management of patients with acute myelopathy. Additionally, we review the state of current knowledge about the epidemiology, natural history, immunopathogenesis ...
... Review Summary: In this article, we summarize recent classification and diagnostic schemes, which provide a framework for the diagnosis and management of patients with acute myelopathy. Additionally, we review the state of current knowledge about the epidemiology, natural history, immunopathogenesis ...
A. UK Guidelines - NHS Greater Glasgow and Clyde
... characteristic findings of acute pancreatitis on CT scan. Risk factors of severity of acute pancreatitis at admission include older age, obesity, and organ failure. Tests at admission that are also helpful in distinguishing mild from severe acute pancreatitis include APACHE-II score >=8 and serum h ...
... characteristic findings of acute pancreatitis on CT scan. Risk factors of severity of acute pancreatitis at admission include older age, obesity, and organ failure. Tests at admission that are also helpful in distinguishing mild from severe acute pancreatitis include APACHE-II score >=8 and serum h ...
HIGHLIGHTS OF PRESCRIBING INFORMATION These
... Mesalamine has been associated with an acute intolerance syndrome that may be difficult to distinguish from an exacerbation of ulcerative colitis. Although the exact frequency of occurrence has not been determined, it has occurred in 3% of controlled clinical trials of mesalamine or sulfasalazine. S ...
... Mesalamine has been associated with an acute intolerance syndrome that may be difficult to distinguish from an exacerbation of ulcerative colitis. Although the exact frequency of occurrence has not been determined, it has occurred in 3% of controlled clinical trials of mesalamine or sulfasalazine. S ...
superantigens in atopic dermatitis
... – Keratoconus is an elongation and protrusion of the corneal surface, which is seen in a few patients with AD. Its appearance is not associated with cataracts. – Patients with AD do have a higher likelihood of cataracts; however, most of these are asymptomatic. The appearance of cataracts may be rel ...
... – Keratoconus is an elongation and protrusion of the corneal surface, which is seen in a few patients with AD. Its appearance is not associated with cataracts. – Patients with AD do have a higher likelihood of cataracts; however, most of these are asymptomatic. The appearance of cataracts may be rel ...
Guide to Writing FAQs - Specialist Pharmacy Service
... hyperkalaemia, hypotension and renal failure compared to their use as monotherapies. (13) In particular, there was concern that the combinations might not lead to the anticipated benefits and therefore risk may outweigh benefits. The review found that the risk was likely to be greater than the benef ...
... hyperkalaemia, hypotension and renal failure compared to their use as monotherapies. (13) In particular, there was concern that the combinations might not lead to the anticipated benefits and therefore risk may outweigh benefits. The review found that the risk was likely to be greater than the benef ...
oral Chemotherapy - Maine Pharmacy Association
... Do not compound oral agents within the cytotoxic drug safety cabinet because of contamination—Differs from some US ...
... Do not compound oral agents within the cytotoxic drug safety cabinet because of contamination—Differs from some US ...
Health Insurance Appeal Letters — A Toolkit for Clinicians —
... system has become even more complex, costly and burdensome for all concerned. Health care costs have continued to rise with no clear consensus on how to contain them. Health plans have responded by shifting more of the cost burden to patients, with even greater scrutiny of providers’ clinical decisi ...
... system has become even more complex, costly and burdensome for all concerned. Health care costs have continued to rise with no clear consensus on how to contain them. Health plans have responded by shifting more of the cost burden to patients, with even greater scrutiny of providers’ clinical decisi ...
How I manage patients with acquired haemophilia A
... with low inhibitor levels (<5 BU) and evidence of insignificant bleeding, or if first-line agents are not readily available (Collins et al, 2010; Franchini & Lippi, 2011). This therapeutic strategy aims to attain effective haemostasis by neutralizing the inhibitor and increasing factor VIII levels u ...
... with low inhibitor levels (<5 BU) and evidence of insignificant bleeding, or if first-line agents are not readily available (Collins et al, 2010; Franchini & Lippi, 2011). This therapeutic strategy aims to attain effective haemostasis by neutralizing the inhibitor and increasing factor VIII levels u ...
Level of magnesium in patients with depression treated with lithium
... an activator of over 300 different enzymes. For the last 60 years lithium (Li+) compounds have been used in psychiatry. Li+ salts are regarded as the first choice medicine in the treatment of affective disorders and are also applied as an adjuvant intensifying the therapy in drug-resistant depressio ...
... an activator of over 300 different enzymes. For the last 60 years lithium (Li+) compounds have been used in psychiatry. Li+ salts are regarded as the first choice medicine in the treatment of affective disorders and are also applied as an adjuvant intensifying the therapy in drug-resistant depressio ...
Hepatitis C - OASIS Clinic
... ◦◦Solid organ transplant (except liver) ◦◦Severe heart/lung disease • Relative ◦◦Autoimmune diseases ◦◦Unstable psychiatric disorder ◦◦Active alcohol/drug use ...
... ◦◦Solid organ transplant (except liver) ◦◦Severe heart/lung disease • Relative ◦◦Autoimmune diseases ◦◦Unstable psychiatric disorder ◦◦Active alcohol/drug use ...
Pediatric ABC`s - Calgary Emergency Medicine
... • Oral steroids given in equipotent doses are equivalent to intravenous steroids • Steroids should be given early in the emergency course • Inhaled steroids may have an adjunctive role • Magnesium may be beneficial in severe cases ...
... • Oral steroids given in equipotent doses are equivalent to intravenous steroids • Steroids should be given early in the emergency course • Inhaled steroids may have an adjunctive role • Magnesium may be beneficial in severe cases ...
creatine kinase-mb - The Professional Medical Journal
... days troponin assays are preferred in the workup of many patients with acute chest pain but CK-MB is still useful if the initial troponin determination is abnormal or if there is suspicion of reinfarction.14 The European Society of Cardiology/American College of Cardiology consensus document notes t ...
... days troponin assays are preferred in the workup of many patients with acute chest pain but CK-MB is still useful if the initial troponin determination is abnormal or if there is suspicion of reinfarction.14 The European Society of Cardiology/American College of Cardiology consensus document notes t ...
Long-term macrolide treatment for chronic respiratory disease Paolo Spagnolo , Leonardo M. Fabbri
... demonstrated a significant decrease in all parameters from baseline to day 28 in the azithromycin group. The effects on neutrophil count, SAA and HsCRP were still present at the end of the study at day 168. There were some correlations between individual inflammatory parameters and weight and spirom ...
... demonstrated a significant decrease in all parameters from baseline to day 28 in the azithromycin group. The effects on neutrophil count, SAA and HsCRP were still present at the end of the study at day 168. There were some correlations between individual inflammatory parameters and weight and spirom ...
LDN - Meridian Kinesiology
... Patients taking thyroid hormone replacement for a diagnosis of Hashimoto’s thyroiditis with hypothyroidism need to begin LDN at the very lowest range (1.5mg for an adult), as LDN may lead to a prompt decrease in the autoimmune disorder, which then may require a rapid reduction in the dose of thyroid ...
... Patients taking thyroid hormone replacement for a diagnosis of Hashimoto’s thyroiditis with hypothyroidism need to begin LDN at the very lowest range (1.5mg for an adult), as LDN may lead to a prompt decrease in the autoimmune disorder, which then may require a rapid reduction in the dose of thyroid ...
Management of Alcohol Withdrawal
... cognition or perceptual disturbance developing in a short period, and the emergence of symptoms during or shortly after withdrawal from heavy alcohol intake (Table 1).4 The classic clinical presentation of AWD also includes hyperpyrexia, tachycardia, hypertension, and diaphoresis. The incidence of A ...
... cognition or perceptual disturbance developing in a short period, and the emergence of symptoms during or shortly after withdrawal from heavy alcohol intake (Table 1).4 The classic clinical presentation of AWD also includes hyperpyrexia, tachycardia, hypertension, and diaphoresis. The incidence of A ...
Duchenne Muscular Dystrophy: Pulmonary - CARE-NMD
... Prevention of Problems • Immunisation with 23-valent pneumoccocal polysaccharide vaccine for patients ≥ 2 years • Annual immunisation with trivalent inactivated influenza vaccine for patients ≥ 6 months • Both can be given to patients on steroids, though immune response to vaccination may be dimini ...
... Prevention of Problems • Immunisation with 23-valent pneumoccocal polysaccharide vaccine for patients ≥ 2 years • Annual immunisation with trivalent inactivated influenza vaccine for patients ≥ 6 months • Both can be given to patients on steroids, though immune response to vaccination may be dimini ...
Urinary Tract Infections in Long Term Care
... antibiotics. Elderly require longer time to present with fever, may not have an increase in temperature or may even be hypothermic. A temperature of 38°C or an increase of 1.1°C above baseline is ...
... antibiotics. Elderly require longer time to present with fever, may not have an increase in temperature or may even be hypothermic. A temperature of 38°C or an increase of 1.1°C above baseline is ...
?+@ #..)zd i~ Blue Cross of California
... Federal Regulations, Food and Drug Administration, Title-21, section 10.30, This regulation provides that drugs limited to prescription use under an NDA can be exempted from that limitation if the FDA determines the prescription requirements to be unnecessary for the protection of public health. My ...
... Federal Regulations, Food and Drug Administration, Title-21, section 10.30, This regulation provides that drugs limited to prescription use under an NDA can be exempted from that limitation if the FDA determines the prescription requirements to be unnecessary for the protection of public health. My ...
Energetic Natural Medicine for Thymus disorders
... unsustainable and requires emergent assistance with a respirator. In these patients, myasthenic crises can be triggered by anything that causes respiratory muscles to overwork and become fatigued, such as a respiratory infection (typically involving spasmodic coughing), fever, asthmatic attacks or a ...
... unsustainable and requires emergent assistance with a respirator. In these patients, myasthenic crises can be triggered by anything that causes respiratory muscles to overwork and become fatigued, such as a respiratory infection (typically involving spasmodic coughing), fever, asthmatic attacks or a ...
Nivolumab in treating advanced melanoma
... the most common. However, serious life-threatening toxicities do occur. Early identification of irAEs is critical in minimising further complications; specific management algorithms exist to guide severity assessment and appropriate treatment. In general, irAEs will respond to corticosteroids, howev ...
... the most common. However, serious life-threatening toxicities do occur. Early identification of irAEs is critical in minimising further complications; specific management algorithms exist to guide severity assessment and appropriate treatment. In general, irAEs will respond to corticosteroids, howev ...
Management of multiple sclerosis
Several therapies for multiple sclerosis (MS) exist, although there is no known cure. Multiple sclerosis is a chronic inflammatory demyelinating disease that affects the central nervous system (CNS).The most common initial course of the disease is the relapsing-remitting subtype, which is characterized by unpredictable attacks (relapses) followed by periods of relative remission with no new signs of disease activity. After some years, many of the people who have this subtype begin to experience neurologic decline without acute relapses. When this happens it is called secondary progressive multiple sclerosis. Other, less common, courses of the disease are the primary progressive (decline from the beginning without attacks) and the progressive-relapsing (steady neurologic decline and superimposed attacks). Different therapies are used for patients experiencing acute attacks, for patients who have the relapsing-remitting subtype, for patients who have the progressive subtypes, for patients without a diagnosis of MS who have a demyelinating event, and for managing the various consequences of MS.The primary aims of therapy are returning function after an attack, preventing new attacks, and preventing disability. As with any medical treatment, medications used in the management of MS may have several adverse effects, and many possible therapies are still under investigation. At the same time different alternative treatments are pursued by many patients, despite the paucity of supporting, comparable, replicated scientific study.This article focuses on therapies for standard MS; borderline forms of MS have particular treatments that are excluded.