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Peripheral Arterial Disease: Evaluation, Risk Factor Modification
Peripheral Arterial Disease: Evaluation, Risk Factor Modification

... Edinburgh Artery Study [14] found that the relative risk of intermittent claudication was 3.7 in smokers compared with 3.0 in previous smokers (who had discontinued smoking for less than 5 years). A recent 4.5-year follow-up study of over 400 patients with documented PAD demonstrated that continued ...
Session 5 - Teaching Slides
Session 5 - Teaching Slides

... – E.g. nausea, anemia, dizziness – Mostly occur early and subside with time – May be managed without switching drug depending on nature and severity – Symptomatic treatment should be offered ...
ALLELOCK Tablets 2.5/5
ALLELOCK Tablets 2.5/5

... Urine sugar ...


... angioedema is prominent, non-steroidal anti-inflammatory drugs, including salicylate containing drugs should always be considered. The patient will nearly always recognise the association themselves. Antibiotic allergy is common and can cause urticaria but is unlikely to manifest as chronic disease ...
Metro South Health | Antibiotics
Metro South Health | Antibiotics

... Seek and treat tinea with 2% miconazole topically. If venous insufficiency is present (and no contra-indications e.g. arterial insufficiency – check ABI) refer to physio OPD for fitting and supply of compression stockings. Ensure good skin condition by using emollients (e.g. aqueous cream or sorbole ...
Faculdade de Medicina da Universidade do Porto Introdução à
Faculdade de Medicina da Universidade do Porto Introdução à

... Despite the limitations and the need for larger confirmatory studies, this study has established feasibility and utility of SMS as a mean of telemedicine of asthma. SMS can contribute to better disease control, symptomatic improvement, and the more favora Compare the efficiency of PEF and symptom se ...
The Multinational Association for Supportive Care in
The Multinational Association for Supportive Care in

... parenteral, sequential (intravenous [IV] followed by oral), or oral antibiotic regimens.12-17 Because these studies were conducted at single centers, using various definitions of low-risk patients and without adequate controls, they cannot be considered as having demonstrated the safety and efficacy ...
Primary_Headaches_Treatment
Primary_Headaches_Treatment

... Abortive therapies-considerations Triptans are contraindicated with ischemic heart disease and complicated migraine (hemiplegic, confusional) Route of treatment determines speed of response and effectiveness: Oral, injectable or nasal spray ...
HIGHLIGHTS OF PRESCRIBING INFORMATION These
HIGHLIGHTS OF PRESCRIBING INFORMATION These

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Complications of Facial Resurfacing
Complications of Facial Resurfacing

... post peel and laser dressing and have not seen any infections since. Figure 3B shows a post-laser herpetic infection. This patient was treated prophylactically with valcyclovir but still developed significant infection. She responded well when the antiviral medication was adjusted to zoster levels. ...
There are some 100 different forms of arthritis,1 rheumatic diseases
There are some 100 different forms of arthritis,1 rheumatic diseases

... blood tests to monitor side effects. In addition to relieving signs and symptoms, these drugs may help to retard or even stop joint damage from progressing. However, DMARDs cannot fix joint damage that has already occurred. Some of the most commonly prescribed DMARDs are methotrexate, hydroxychloroq ...
Current management of dermatomyositis
Current management of dermatomyositis

... the absence of evidence of muscle inflammation (normal muscle strength and muscle enzymes) for at least 6  months [6] . It is estimated that 10–20% of DM patients seen in academic centers have amyopathic disease [7] . Furthermore, a substantial number of patients with treated DM will continue to suf ...
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... rebleeding was 31% in the injection only group and 0% for the combination group (p< 0,05) Re-bleeding rate in adrenaline - only group is 17% compared to 4,42% in the combination group - clinically meaningful but NSS. ...
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... Insights into the pathogenesis of psoriasis coupled with a detailed understanding of the action of cytokines and their associated transduction pathways have yielded a number of new therapeutic targets. Psoriasis is a chronic condition and, therefore, requires ongoing management with safe and effecti ...
Clinical Pharmacokinetics of Once Daily IV Bolus Gentamicin in
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... are 4-10mg/L [7]. Evidence suggests that high peak plasma concentrations must be achieved early in the course of treatment if gentamicin is to be effective, but prolonged high concentrations may cause ototoxicity and nephrotoxicity [8]. In order to choose any mode of dosing, correct interpretation o ...
Symptom Management Pocket Guide: Delirium
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... with the newer atypical neuroleptics having a lower risk of EPS than the older typical neuroleptics. ...
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... occur when recurrent use of the substance results in a pathological pattern of related behaviors, e.g., impaired control and social impairment. The 2014 NSDUH reported that approximately 21.5 million people aged 12 and older in 2014 had SUDs in the past year, including 7.1 million with an illicit dr ...
Porphyria Cutanea Tarda (PCT) Patient Information Leaflet
Porphyria Cutanea Tarda (PCT) Patient Information Leaflet

... The body uses iron to make more blood and the process is repeated until the excess iron has been removed. In the genetic disorder haemochromatosis, which may occur in association with PCT, removal of excess iron may need to be on a long-term basis.  Low-dose hydroxychloroquine may be prescribed (us ...
2002 ACC/AHA Guidelines. CRUSADE Quality Improvement
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... appropriately receive both acute and dis- ...
Regional Anesthesia in the Patient with Preexisting Neurologic
Regional Anesthesia in the Patient with Preexisting Neurologic

... frequent, and recovered more slowly than those produced by long-beveled needles. Although no human studies have been performed to determine which of these in vitro studies accurately predicts clinical outcome, these studies illustrate the importance of minimizing direct needle trauma during regiona ...
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Weird Fungi

... pathogen. While there are clinical circumstances in which obtaining histopathology and culture from a sterile body site is simply not possible, such as in the case of a severely neutropenic/thrombocytopenic cancer patient, there is simply no substitute for accurate clinical mycology in patients that ...
CNSstimulants -L3
CNSstimulants -L3

DermaDilemma - Turner White Communications
DermaDilemma - Turner White Communications

... the stratum corneum of the proximal nail fold. The infection then spreads to the deeper portions of the nail plate. Initial causes of PWSO infection can include trauma and immunosuppression. The explanation for the increased incidence of PWSO in patients with AIDS is unclear; most likely, the immuno ...
True infliximab resistance in rheumatoid arthritis: a role for
True infliximab resistance in rheumatoid arthritis: a role for

... possible explanations seem likely this suggests that other cytokines within the complex network may possess a pathogenic role. The presence of LTa staining in the preinjection synovial biopsy specimen of our patient may be relevant to explaining the subsequent outcome. Evidence suggests that chronic ...
Caelyx, Concentrate for infusion
Caelyx, Concentrate for infusion

... For common adverse events which required dose modification or discontinuation see ADVERSE REACTIONS. Cardiac Risk Experience with CAELYX at high cumulative doses is too limited to have established its effects on the myocardium (see ADVERSE REACTIONS). Moreover, the longterm cardiac effects of CAELYX ...
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Management of multiple sclerosis



Several therapies for multiple sclerosis (MS) exist, although there is no known cure. Multiple sclerosis is a chronic inflammatory demyelinating disease that affects the central nervous system (CNS).The most common initial course of the disease is the relapsing-remitting subtype, which is characterized by unpredictable attacks (relapses) followed by periods of relative remission with no new signs of disease activity. After some years, many of the people who have this subtype begin to experience neurologic decline without acute relapses. When this happens it is called secondary progressive multiple sclerosis. Other, less common, courses of the disease are the primary progressive (decline from the beginning without attacks) and the progressive-relapsing (steady neurologic decline and superimposed attacks). Different therapies are used for patients experiencing acute attacks, for patients who have the relapsing-remitting subtype, for patients who have the progressive subtypes, for patients without a diagnosis of MS who have a demyelinating event, and for managing the various consequences of MS.The primary aims of therapy are returning function after an attack, preventing new attacks, and preventing disability. As with any medical treatment, medications used in the management of MS may have several adverse effects, and many possible therapies are still under investigation. At the same time different alternative treatments are pursued by many patients, despite the paucity of supporting, comparable, replicated scientific study.This article focuses on therapies for standard MS; borderline forms of MS have particular treatments that are excluded.
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