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Delirium - LSU School of Medicine
Delirium - LSU School of Medicine

... focus, sustain or shift attention. A change in cognition (such as memory deficit, disorientation, language disturbance) or the development of a perceptual disturbance that is not better accounted for by a preexisting, established or evolving dementia. The disturbance develops over a short period of ...
Management of opportunist mycobacterial infections: Joint
Management of opportunist mycobacterial infections: Joint

... is sensitivity testing for rifampicin and ethambutol in M kansasii infection (and clarithromycin sensitivity testing in HIV positive patients). Synergy between drugs to which resistance may have been reported in vitro on single agent testing may be of importance in vivo.40 41 It is preferable that p ...
Neuro_Basis_of_AK__by_Dr._Walter_Schmitt
Neuro_Basis_of_AK__by_Dr._Walter_Schmitt

... responses, and compared with the predicted responses, allowing the clinician to derive data about the state of the patient's neuraxis.” ...
Rhinocerebral Mucormycosis in Diabetes
Rhinocerebral Mucormycosis in Diabetes

... diabetic mellitus, and organ transplantation 4. About 70% to 80% of these patients have diabetes mellitus. As is reported in our case, most diabetics who develop rhinocerebral mucormycosis (RCM) are in poor metabolic control with complicating ketoacidosis 5. It is suggested that fungal organism grow ...
Neurochemical hypotheses
Neurochemical hypotheses

... 2 weeks to start working despite raising the levels of neurotransmitter almost immediately; therefore the ways they work must be more complex than it first appears, e.g. they may work by altering the sensitivity of the post-synaptic receptors, (Kennett, 1999) ...
managing malabsorption and poor feed tolerance
managing malabsorption and poor feed tolerance

... – Presence of infection (e.g. C.difficile, Helicobacter pylori and other bowel pathogens) – if infection is suspected, send a stool sample for culture and sensitivity (anti-diarrhoeals should not be prescribed in the event of infection) t Assess for GI bleeding e.g. dark / black / tarry stool (lower ...
Strategies for managing systemic fungal infection and the place of itraconazole *
Strategies for managing systemic fungal infection and the place of itraconazole *

Acute stroke
Acute stroke

... The proper functioning of this system, its ascending projections to the cortex, and the cortex itself are required to maintain alertness and coherence of thought. It follows that the principal causes of coma are (1) lesions that damage the RAS in the upper midbrain or its projections; (2) destructio ...
lupus ppt for website
lupus ppt for website

... Others- Prasterone,Thalidomide,Acetretin ...
Lec 3: Management of Temporomandibular Disorders.
Lec 3: Management of Temporomandibular Disorders.

... reperfusion injury, and (3) neurogenic inflammation Mechanical trauma may be a result of significant and obvious trauma to the joint or much less obvious microtrauma, such as excessive mechanical loading. The excessive stress produced in the joint can lead to molecular disruption and the generation ...
Antiepileptic Drugs
Antiepileptic Drugs

... Monotherapy preferred- simplifies Rx, fewer adverse effects and drug interactions ~70-80% seizures are controlled on monotherapy ...
A comparative study on the efficacy of levofloxacin and
A comparative study on the efficacy of levofloxacin and

... antibiotics protect respiratory epithelium in its interaction with respiratory pathogens such as H. influenzae [13] and P. aeruginosa [15], it is conventional wisdom to try to achieve supra-MIC at the target sites. The empirical use of antibiotics, pending results of sputum culture, is commonly prac ...
Racemic Drugs: Racemic Mixture, Racemic Compound, or
Racemic Drugs: Racemic Mixture, Racemic Compound, or

... failure in children that is due to a lack of hGH production by the body. Before the introduction of recombinant hGH the hormone was derived from human cadavers. Cadaver-derived hGH was susceptible to contamination with slow viruses that attack nerve tissue. Such infective agents caused fatal illness ...
Microbial evaluation of proton-pump inhibitors and the risk of pneumonia
Microbial evaluation of proton-pump inhibitors and the risk of pneumonia

... incidence of CAP. The shortcomings of this approach are inherent to retrospective epidemiological research on administrative databases. Misclassification of cases might have occurred because clinical information (such as radiographic data) was not always available. Confounding by indication and prot ...
Extra-corporeal Photopheresis in the Management of Graft
Extra-corporeal Photopheresis in the Management of Graft

... in patients surviving the first few months following an allogeneic transplant. As with aGVHD, first-line therapy for patients includes corticosteroids ± a calcineurin inhibitor (28,29). As outlined above, patients with cGVHD have compromised quality of life and decreased survival. Patients who fail ...
投影片 1
投影片 1

... • In addition to these key defining characteristics, patients report various nonspecific symptoms, including weakness, muscle pain, impaired memory and/or mental concentration, insomnia, and post-exertional fatigue lasting more than 24 hours. • In some cases, CFS can persist for years. ...
description - Boehringer Ingelheim
description - Boehringer Ingelheim

... Estrogens, Including Oral Contraceptives: Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. Hepatic Enzyme Inducers, Inhibitors and Substrates: Drugs which induce cytochrome P450 3A4 (CYP 3A4) enzyme activity (e.g., barbiturates, phenytoin, c ...
Pharmacoeconomics of anticoagulation therapy for stroke
Pharmacoeconomics of anticoagulation therapy for stroke

... One limitation of these pharmacoeconomic studies is that they are based on the results of controlled clinical trials that were performed in selected patients and generally achieved high levels of anticoagulation control. Maintaining optimal anticoagulation, particularly at levels recommended by inte ...
Care of the Hospitalized Patient with Acute Exacerbation of COPD
Care of the Hospitalized Patient with Acute Exacerbation of COPD

... (i.e., Combivent and Duoneb) are available. It is reasonable to hold long-acting beta-agonists and anticholinergics when receiving scheduled doses of short-acting agents. May result in less beta-adrenergic side effects than albuterol, but there is a paucity of clinical data supporting its use, and i ...
A phase III randomized trial comparing glucocorticoid monotherapy
A phase III randomized trial comparing glucocorticoid monotherapy

... Conventional treatment of WAIHA includes corticosteroids as first-line therapy, which is associated with long-term remission in approximately 30% of patients (Petz, 2001). In ª 2013 John Wiley & Sons Ltd British Journal of Haematology, 2013, 163, 393–399 ...
Endogenous reactivation and true treatment failure as causes of
Endogenous reactivation and true treatment failure as causes of

... For 30 of the 35 patients, spoligotyping, RFLP and/or MIRU-VNTR patterns of the M. tuberculosis strains responsible for the TB recurrence were identical (28 cases) or showed an addition and a deletion of one IS6110 fragment (two cases), but were identical by MIRU-VNTR, indicating endogenous reactiva ...
Ethical issues related to the use of placebo in clinical trials
Ethical issues related to the use of placebo in clinical trials

... Controversy exists regarding the ethics of using placebo control groups in clinical trials when effective treatments exist. The debate was fuelled by the announcement of the fifth revision of the Declaration of Helsinki in 2000. This study reviews the history and scientific background surrounding th ...
2008 AOA Review
2008 AOA Review

... antidbody) is associated with peripheral venous thrombosis and ischemic (arterial) stroke. In patients with a history of DVT, the possibility of a paradoxical embolus causing a stroke (via rightto-left cardiac shunt) should also be considered. Nonvalvular atrial fibrillation is a common cause of str ...
Bacillus Calmette-Guerin— Another Surprise!
Bacillus Calmette-Guerin— Another Surprise!

... during this period the patient lies prone for 15 minutes, supine for 15 minutes and 15 minutes on each side. This ensures that all of the bladder mucosa comes into contact with the BCG. Caution is suggested in handling the BCG as there is a small risk of tuberculosis infection. The staff administeri ...
- European Medical Journal
- European Medical Journal

... hyperkalaemia treatments have several important limitations so the need for new treatment options is becoming more apparent. The only treatment options currently available are temporising agents such as intravenous calcium, alkalinisation agents (such as sodium bicarbonate), glucose and insulin, and ...
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Management of multiple sclerosis



Several therapies for multiple sclerosis (MS) exist, although there is no known cure. Multiple sclerosis is a chronic inflammatory demyelinating disease that affects the central nervous system (CNS).The most common initial course of the disease is the relapsing-remitting subtype, which is characterized by unpredictable attacks (relapses) followed by periods of relative remission with no new signs of disease activity. After some years, many of the people who have this subtype begin to experience neurologic decline without acute relapses. When this happens it is called secondary progressive multiple sclerosis. Other, less common, courses of the disease are the primary progressive (decline from the beginning without attacks) and the progressive-relapsing (steady neurologic decline and superimposed attacks). Different therapies are used for patients experiencing acute attacks, for patients who have the relapsing-remitting subtype, for patients who have the progressive subtypes, for patients without a diagnosis of MS who have a demyelinating event, and for managing the various consequences of MS.The primary aims of therapy are returning function after an attack, preventing new attacks, and preventing disability. As with any medical treatment, medications used in the management of MS may have several adverse effects, and many possible therapies are still under investigation. At the same time different alternative treatments are pursued by many patients, despite the paucity of supporting, comparable, replicated scientific study.This article focuses on therapies for standard MS; borderline forms of MS have particular treatments that are excluded.
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