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Rethinking placebo in psychiatry: how and why placebo effects occur†
Rethinking placebo in psychiatry: how and why placebo effects occur†

... confidence (Kaptchuk 2008). Doctors who were positive and enthusiastic when delivering a placebo increased its effectiveness compared with doctors who were more apathetic about the same treatment (Gryll 1978). What doctors believe about the treatments they are administering can affect clinical outco ...
Rheumatoid arthritis is an autoimmune disease that causes chronic
Rheumatoid arthritis is an autoimmune disease that causes chronic

...  About 80% of subjects test positive for rheumatoid factor, making it a useful diagnostic  Rheumatoid factor is an immunoglobulin (antibody) which can bind to other antibodies. Antibodies are normal proteins found in the blood which function within the immune system. Rheumatoid factor though is no ...
Common fungi - Fungal Infection Trust
Common fungi - Fungal Infection Trust

... 90% of control mice. Kidneys and lungs from survivors were cultured on day 11. Against AF71, all three doses of SCH and ITZ yielded a 90 to 100% survival rate and AB yielded 40% survival (P < or = 0.01 to 0.0001 for all treatment groups compared with the controls). All three doses of SCH were superi ...
SERIES ‘‘RARE INTERSTITIAL LUNG DISEASES’’ Number 1 in this Series
SERIES ‘‘RARE INTERSTITIAL LUNG DISEASES’’ Number 1 in this Series

... mesenchymal origin, containing smooth muscle, blood vessels and fat. The presence of fat in these lesions gives a characteristic CT appearance (fig. 2); diagnostic difficulty may arise in the small number of angiomyolipomas that do not contain fat. If the diagnosis of LAM is secure, these lesions ar ...
J Kanjee STATUS ASTHMATICUS - Waiting to Exhale
J Kanjee STATUS ASTHMATICUS - Waiting to Exhale

... As a result of inadequate alveolar ventilation status asthmaticus patients develop varying degrees of hypoxaemia, hypercapnia and lactic acidosis. Studies of patients with respiratory failure secondary to acute severe asthma using multiple inert gas-elimination techniques have shown that bimodality ...
strategies for the management of opioid
strategies for the management of opioid

... may cause significant disturbance of consciousness and comprehension. Delirium may also be exacerbated by comorbid conditions or other drug therapy. The risk of delirium may be greater with highly lipophilic opioids, which produce more rapid receptor occupancy. Management of delirium in an opioid-tr ...
Parkinson`s Disease Medications
Parkinson`s Disease Medications

... healthcare provider, the person with PD and his or her care partner to determine a treatment plan consisting of appropriate medications, regular exercise, a healthy diet, social engagement and cognitive activities, counseling and other therapies. As the disease progresses and problems accumulate, de ...
Premenstrual Dysphoric Disorder
Premenstrual Dysphoric Disorder

... allopregenolone, on the other hand, has anxiolytic properties, and so there has been interest in using its precursor, progesterone, during the luteal phase. Unfortunately, several controlled trials have shown progesterone to be no more effective than placebo. Because benzodiazepines act on GABA rece ...
Supplement to Supplement to Rheumatology News
Supplement to Supplement to Rheumatology News

... by a continuous interaction of numerous cells, molecules, and processes. A striking pathological change is the transition of the synovial lining from 2 to 3 layers of fibroblast-like synoviocytes (FLS) into several layers of macrophage-like cells.1 In health, the synovial lining is a veil-like struc ...
Acute exacerbation of chronic obstructive pulmonary disease and
Acute exacerbation of chronic obstructive pulmonary disease and

... natural course. Thus, a first step is to discriminate between symptoms related to the natural course of COPD and those caused by an AECB. It has been reported in the literature that various laboratory findings are associated with clinical "acute exacerbations" of chronic bronchitis (table 1). The st ...
Pages 11-24
Pages 11-24

... order to retain patients in treatment. One recent, large scale RCT suggests that combined MI, CBT and family therapy can be an effective approach for reducing substance use among schizophrenic patients for at least one year (Barrowclough et al., 2010). Another study found a once weekly, 90 minute gr ...
Interferences with Ventilation
Interferences with Ventilation

...  Collaborative Care:  Avoidance is the best treatment  House dust, dust mites, mold spores, pollens, pet allergens, smoke  Medications: nasal sprays, antihistamines, decongestants  Nasal corticosteroid sprays – decrease inflammation  Local with little systemic absorption ...
Development and Validation of the First Iranian Questionnaire to
Development and Validation of the First Iranian Questionnaire to

... Chronic heart failure is a chronic condition with enormous impact on the lifestyle of patients (2-11). In Iran the prevalence of chronic heart failure has been estimated at the rate of 3337 in 10000 (9). Heart failure adversely affects quality of life because of changes in lungs, circulation, and sk ...
Orbital and Adnexal Sarcoidosis
Orbital and Adnexal Sarcoidosis

... ary liver and lung lesions 5 years following orbital involvement). The patient who developed a right-sided facial palsy (4 weeks into the follow-up period) also had bilateral granulomatous anterior uveitis, vitritis, and left optic disc edema (suggestive of Heerfordt syndrome). None of the patients ...
Issues In-Depth: Advancing Understanding of Drug Addiction and
Issues In-Depth: Advancing Understanding of Drug Addiction and

... is expected that results from the clinical trials on vigabatrin will be available in 2009, along with an examination of any side effects and potential dangers of treatment. ...
Efficacy of Topical Pilocarpine in the Management of Primary
Efficacy of Topical Pilocarpine in the Management of Primary

... In most cases, the symptoms are associated with a decrease in lacrimal gland secretion causing reduced tear volume that triggers an inflammatory response resulting to ocular manifestations. Since almost 90% of the total volume of the tear film is made up of the middle aqueous layer and at least 65% ...
Biologics - National Rheumatoid Arthritis Society
Biologics - National Rheumatoid Arthritis Society

... causing damage to cartilage and bone around the joints. Any joint may be affected but it is commonly the hands, feet and wrists. Some people have very little damage to their joints, and about one person in 20 has severe damage in several joints. RA is a systemic disease which means that it can aff ...
Mind-Body Medicine: An Overview - Innovative Educational Services
Mind-Body Medicine: An Overview - Innovative Educational Services

... and health care systems, practices, and products that are not presently considered to be a part of conventional medicine. People use CAM therapies in a variety of ways. CAM therapies used alone are often referred to as "alternative." When used in addition to conventional medicine, they are often ref ...
Diagnosis and current therapy of Wilson`s disease
Diagnosis and current therapy of Wilson`s disease

... E-mail: [email protected] Ó 2003 Blackwell Publishing Ltd ...
10-021 OTC.indd
10-021 OTC.indd

... disease or diagnosis. Heartburn that is frequent and persistent (3 months or longer) is the most common symptom of gastroesophageal reflux disease (GERD). An international consensus panel recently defined GERD as a condition that develops when the reflux of stomach contents causes troublesome sympt ...
Immunosuppressive and Cytotoxic Therapy: Pharmacology
Immunosuppressive and Cytotoxic Therapy: Pharmacology

... CYC has been associated with an increased risk of carcinomas of the skin,50,55 female genital tract (predominantly cervical atypia),56 and malignant lymphoproliferative disorders.3,30,38,39,51 The risk of neoplasia associated with CYC is dose dependent. Malignancies may develop 5 to 15 years after i ...
Management of balanitis
Management of balanitis

... once or twice daily. 16  (IV,C) · Hygiene measures  Alternative treatments · CO2  laser  ­  this  has  been  used  to  treat  individual  lesions 17 . (IV,C) · Although  topical  tacrolimus  has  been  reported  in the  treatment  of  Zoon’s  balanitis 18  (IV,C)  there  are  serious  concerns  abou ...
EFNS task force on management of amyotrophic lateral sclerosis: guidelines
EFNS task force on management of amyotrophic lateral sclerosis: guidelines

Common Misconceptions About Lyme Disease
Common Misconceptions About Lyme Disease

... brain infection. strable. Consequently, many paspirochetal infection often likened tients with early Lyme disease are to Lyme disease) provide supportseronegative.4 However, the vast ing evidence against the conclumajority of such patients have a characteristic skin lesion sion that partial treatmen ...
Heart Failure:
Heart Failure:

... alter the risk of MI or hemorrhagic stroke, but it did reduce the risk of ischemic stroke by 24%. Among men, aspirin reduced the risk of major cardiovascular events by 14%, and of MI by 32%. While it had no effect on the risk of ischemic stroke among men, it did increase their risk of hemorrhagic st ...
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Management of multiple sclerosis



Several therapies for multiple sclerosis (MS) exist, although there is no known cure. Multiple sclerosis is a chronic inflammatory demyelinating disease that affects the central nervous system (CNS).The most common initial course of the disease is the relapsing-remitting subtype, which is characterized by unpredictable attacks (relapses) followed by periods of relative remission with no new signs of disease activity. After some years, many of the people who have this subtype begin to experience neurologic decline without acute relapses. When this happens it is called secondary progressive multiple sclerosis. Other, less common, courses of the disease are the primary progressive (decline from the beginning without attacks) and the progressive-relapsing (steady neurologic decline and superimposed attacks). Different therapies are used for patients experiencing acute attacks, for patients who have the relapsing-remitting subtype, for patients who have the progressive subtypes, for patients without a diagnosis of MS who have a demyelinating event, and for managing the various consequences of MS.The primary aims of therapy are returning function after an attack, preventing new attacks, and preventing disability. As with any medical treatment, medications used in the management of MS may have several adverse effects, and many possible therapies are still under investigation. At the same time different alternative treatments are pursued by many patients, despite the paucity of supporting, comparable, replicated scientific study.This article focuses on therapies for standard MS; borderline forms of MS have particular treatments that are excluded.
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