Global Monoclonal Antibodies Pipeline Analysis Brochure
... pharmaceutical industry. In 2012, there were more than 30 monoclonal antibody therapies approved by the FDA which generated annual sales of more than US$ 40 Billion. As the therapeutic mABs already play a significant part in effective medical treatment, it is most likely that their importance would ...
... pharmaceutical industry. In 2012, there were more than 30 monoclonal antibody therapies approved by the FDA which generated annual sales of more than US$ 40 Billion. As the therapeutic mABs already play a significant part in effective medical treatment, it is most likely that their importance would ...
Heart Failure:
... alter the risk of MI or hemorrhagic stroke, but it did reduce the risk of ischemic stroke by 24%. Among men, aspirin reduced the risk of major cardiovascular events by 14%, and of MI by 32%. While it had no effect on the risk of ischemic stroke among men, it did increase their risk of hemorrhagic st ...
... alter the risk of MI or hemorrhagic stroke, but it did reduce the risk of ischemic stroke by 24%. Among men, aspirin reduced the risk of major cardiovascular events by 14%, and of MI by 32%. While it had no effect on the risk of ischemic stroke among men, it did increase their risk of hemorrhagic st ...
Mechanical Thrombectomy with Stent Retrievers in Acute Basilar
... the impreciseness of this score in vertebrobasilar strokes and the arbitrary values in intubated patients. NIHSS improvement ⱖ10 points was reached in 54% of patients (n ⫽ 13/24). Mortality at discharge was 25% (n ⫽ 6) and at 3 months 29% (n ⫽ 7), respectively. After 3 months, 8 patients (33%) had a ...
... the impreciseness of this score in vertebrobasilar strokes and the arbitrary values in intubated patients. NIHSS improvement ⱖ10 points was reached in 54% of patients (n ⫽ 13/24). Mortality at discharge was 25% (n ⫽ 6) and at 3 months 29% (n ⫽ 7), respectively. After 3 months, 8 patients (33%) had a ...
Michael pieces together
... pharmacology necessarily involves a relatively broad scope of drug classes. Nurses are on the front lines in administering drugs that are specifically designed to treat the socalled pathological triad of pulmonary disease: bronchospasm, airway inflammation, and retained secretions. Their front line ...
... pharmacology necessarily involves a relatively broad scope of drug classes. Nurses are on the front lines in administering drugs that are specifically designed to treat the socalled pathological triad of pulmonary disease: bronchospasm, airway inflammation, and retained secretions. Their front line ...
Foot drop in MS: Evaluation and Treatment 5/20/2014
... Can be progressive-should we therefore be involved in ...
... Can be progressive-should we therefore be involved in ...
- Osteoarthritis and Cartilage
... were evaluated separately and the data were not included in our analyses. In each of these cases the more painful knee was treated first, and only data from the first knee were included in the study. Two patients (one ACS and one HA) were excluded from statistical analysis after exclusion criteria b ...
... were evaluated separately and the data were not included in our analyses. In each of these cases the more painful knee was treated first, and only data from the first knee were included in the study. Two patients (one ACS and one HA) were excluded from statistical analysis after exclusion criteria b ...
What is dysautonomia? - Dysautonomia Youth Network of America
... of the hardest things for these children to deal with. Since youth with dysautonomia are usually normal in appearance, it can be a hard condition for people to understand. Even general physicians sometimes miss the clues leading to a proper diagnosis. Families often find themselves desperately trave ...
... of the hardest things for these children to deal with. Since youth with dysautonomia are usually normal in appearance, it can be a hard condition for people to understand. Even general physicians sometimes miss the clues leading to a proper diagnosis. Families often find themselves desperately trave ...
A Patient`s Guide
... for you to receive SIRT safely. Normally patients will undergo two procedures under conscious sedation. Both procedures will include a radiology procedure known as an angiogram. The purpose of the first angiogram or mapping is to prepare your liver for the SIRT treatment. During the mapping procedur ...
... for you to receive SIRT safely. Normally patients will undergo two procedures under conscious sedation. Both procedures will include a radiology procedure known as an angiogram. The purpose of the first angiogram or mapping is to prepare your liver for the SIRT treatment. During the mapping procedur ...
immunotherapy in allergic diseases
... Immunotherapy is effective in patients with allergy to insect stings, allergic rhino conjunctivitis and in some patients with asthma who have been correctly diagnosed through a cautious history and corroborated with positive skin test results ...
... Immunotherapy is effective in patients with allergy to insect stings, allergic rhino conjunctivitis and in some patients with asthma who have been correctly diagnosed through a cautious history and corroborated with positive skin test results ...
Efficacy of Immediate and Delayed Cognitive and Physical Rest for
... concussed rats has been shown to delay recovery if administered too soon following.6 In athletes, engaging in activities requiring high levels of physical exertion after concussion is associated with greater impairment on neurocognitive testing and higher symptom endorsement.7 There are select studi ...
... concussed rats has been shown to delay recovery if administered too soon following.6 In athletes, engaging in activities requiring high levels of physical exertion after concussion is associated with greater impairment on neurocognitive testing and higher symptom endorsement.7 There are select studi ...
5, PAIN TREATMENTS
... older with osteoarthritis of the knee. Participants had significant pain in their knee the month before joining the study, but had never experienced acupuncture, had not had knee surgery in the previous 6 months, and had not used steroid or similar injections. Participants were randomly assigned to ...
... older with osteoarthritis of the knee. Participants had significant pain in their knee the month before joining the study, but had never experienced acupuncture, had not had knee surgery in the previous 6 months, and had not used steroid or similar injections. Participants were randomly assigned to ...
Cover - Canadian Guidelines on Parkinson`s Disease
... professionals. However, they may also be used by stakeholders (policy makers, funding bodies) and people with Parkinson’s disease and their families. These recommendations are intended to serve as a guide for health care providers, and clinical discretion should be used by all who are following the ...
... professionals. However, they may also be used by stakeholders (policy makers, funding bodies) and people with Parkinson’s disease and their families. These recommendations are intended to serve as a guide for health care providers, and clinical discretion should be used by all who are following the ...
A Phase I Study of Recombinant Interleukin 2 plus Recombinant
... of IL-2 and the duration of its administration. These trials have often included the coadministration of ex vivo IL-2-activated autologous peripheral blood lymphocytes (lymphokine-activated killer cells). It is unclear whether the use of LAK adds to the efficacy of IL-2 used alone and how much LAK c ...
... of IL-2 and the duration of its administration. These trials have often included the coadministration of ex vivo IL-2-activated autologous peripheral blood lymphocytes (lymphokine-activated killer cells). It is unclear whether the use of LAK adds to the efficacy of IL-2 used alone and how much LAK c ...
View Prescribing Details
... day the change of formulation is made. Patients should be converted to oral treatment as soon as possible. Duration of Treatment The administration of continuous multiple daily doses of Ketorolac intramuscularly or intravenously should not exceed 2 days because adverse events may increase with prolo ...
... day the change of formulation is made. Patients should be converted to oral treatment as soon as possible. Duration of Treatment The administration of continuous multiple daily doses of Ketorolac intramuscularly or intravenously should not exceed 2 days because adverse events may increase with prolo ...
R.N. 70269/98 Postal Registration No.: DL-SW-1/4082/12-14 ISSN : 0972-169X
... “But the person who has a rightful place in history as ‘father’ of the idea of continental drift, who, unlike other people who speculated about the possibilities, worked out a detailed model—which was not entirely right, but that is besides the point since few models are—and kicked up a fuss about h ...
... “But the person who has a rightful place in history as ‘father’ of the idea of continental drift, who, unlike other people who speculated about the possibilities, worked out a detailed model—which was not entirely right, but that is besides the point since few models are—and kicked up a fuss about h ...
Vertebrobasilar Occlusion and Vertebral Artery Syndrome
... Consider endotracheal intubation (Glasgow Coma Scale less than 8). Sedation and muscle relaxation may be needed if agitated or resisting mechanical ventilation but these will have to be reversed before a full neurological assessment can be carried out. Thrombolysis (see also separate Thrombolytic Tr ...
... Consider endotracheal intubation (Glasgow Coma Scale less than 8). Sedation and muscle relaxation may be needed if agitated or resisting mechanical ventilation but these will have to be reversed before a full neurological assessment can be carried out. Thrombolysis (see also separate Thrombolytic Tr ...
Postpartum Complicated by Transverse Myelitis Postparto
... The use of corticosteroids is the standard first line of treatment, however, due to the rarity of the disease, there are ...
... The use of corticosteroids is the standard first line of treatment, however, due to the rarity of the disease, there are ...
Hematology…Literally and Seriously
... This report carries with it all the caveats in interpretation inherent in retrospective data. While the authors carefully adjusted for clinical factors that could affect outcomes to limit bias, there may still be confounding factors that are important to discuss. That said, while perhaps not practic ...
... This report carries with it all the caveats in interpretation inherent in retrospective data. While the authors carefully adjusted for clinical factors that could affect outcomes to limit bias, there may still be confounding factors that are important to discuss. That said, while perhaps not practic ...
Therapy-Induced Encephalopathy
... cytotoxic concentrations of the drug in the CSF for up to 14 days CSF exposure up to 40x that of standard Ara-C Onset: As early as 2-5 days after treatment13 May resolve spontaneously within a few days or may be permanent23,13 ...
... cytotoxic concentrations of the drug in the CSF for up to 14 days CSF exposure up to 40x that of standard Ara-C Onset: As early as 2-5 days after treatment13 May resolve spontaneously within a few days or may be permanent23,13 ...
Neurocysticercosis Among Children in Chicago
... fied by reviews of (1) medical records of all inpatients and outpatients whose discharge diagnosis was cysticercosis or neurocysticercosis, (2) laboratory serology records, (3) pathology records, and (4) the Division of Infectious Diseases' outpatient clinical and consultation records. Patients were ...
... fied by reviews of (1) medical records of all inpatients and outpatients whose discharge diagnosis was cysticercosis or neurocysticercosis, (2) laboratory serology records, (3) pathology records, and (4) the Division of Infectious Diseases' outpatient clinical and consultation records. Patients were ...
Distinguishing Musculoskeletal from Neurologic Disease
... neck pain may include tensing of muscle, trigger points (intense spasming and flinching when pressure is applied), or a cry of pain. Cervical range of motion should be attempted cautiously, if at all, as range of motion can worsen some neurologic diseases. In most cases, neck range of motion is best ...
... neck pain may include tensing of muscle, trigger points (intense spasming and flinching when pressure is applied), or a cry of pain. Cervical range of motion should be attempted cautiously, if at all, as range of motion can worsen some neurologic diseases. In most cases, neck range of motion is best ...
Understanding Dexamethasone and Other Steroids
... Dexamethasone and other steroids, particularly prednisone, prednisolone, and methylprednisolone, have many uses in the treatment of cancer. They suppress certain actions of the immune system and also inhibit cytokines, which are chemicals in the body that control inflammation. Dexamethasone decrease ...
... Dexamethasone and other steroids, particularly prednisone, prednisolone, and methylprednisolone, have many uses in the treatment of cancer. They suppress certain actions of the immune system and also inhibit cytokines, which are chemicals in the body that control inflammation. Dexamethasone decrease ...
PDF - Skin Therapy Letter
... AD is a highly pruritic inflammatory disorder that is characterized by childhood onset and that usually assumes a chronically relapsing course.1 The incidence of AD has increased in recent years with a prevalence of 7%-21% in school-age children, but it is also common in adolescents and adults.1 Imm ...
... AD is a highly pruritic inflammatory disorder that is characterized by childhood onset and that usually assumes a chronically relapsing course.1 The incidence of AD has increased in recent years with a prevalence of 7%-21% in school-age children, but it is also common in adolescents and adults.1 Imm ...
Does antipsychotic withdrawal provoke psychosis? Review of the
... provide some evidence. Although the studies did not specifically identify a new onset psychotic syndrome after withdrawal [see review in Lacoursiere (25)], some did report severe and rapid deterioration in some patients, compatible with rapid onset psychosis (26, 27). One also notes new onset halluci ...
... provide some evidence. Although the studies did not specifically identify a new onset psychotic syndrome after withdrawal [see review in Lacoursiere (25)], some did report severe and rapid deterioration in some patients, compatible with rapid onset psychosis (26, 27). One also notes new onset halluci ...
Adult Chemotherapy Induced Anaphylaxis Policy
... Anaphylaxis requires rapid recognition, treatment and management by health professionals. Cancer chemotherapy drugs are foreign substances able to induce anaphylaxis and reactions range from mild cutaneous symptoms to severe respiratory distress and cardiovascular collapse. This adverse/allergic rea ...
... Anaphylaxis requires rapid recognition, treatment and management by health professionals. Cancer chemotherapy drugs are foreign substances able to induce anaphylaxis and reactions range from mild cutaneous symptoms to severe respiratory distress and cardiovascular collapse. This adverse/allergic rea ...
Management of multiple sclerosis
Several therapies for multiple sclerosis (MS) exist, although there is no known cure. Multiple sclerosis is a chronic inflammatory demyelinating disease that affects the central nervous system (CNS).The most common initial course of the disease is the relapsing-remitting subtype, which is characterized by unpredictable attacks (relapses) followed by periods of relative remission with no new signs of disease activity. After some years, many of the people who have this subtype begin to experience neurologic decline without acute relapses. When this happens it is called secondary progressive multiple sclerosis. Other, less common, courses of the disease are the primary progressive (decline from the beginning without attacks) and the progressive-relapsing (steady neurologic decline and superimposed attacks). Different therapies are used for patients experiencing acute attacks, for patients who have the relapsing-remitting subtype, for patients who have the progressive subtypes, for patients without a diagnosis of MS who have a demyelinating event, and for managing the various consequences of MS.The primary aims of therapy are returning function after an attack, preventing new attacks, and preventing disability. As with any medical treatment, medications used in the management of MS may have several adverse effects, and many possible therapies are still under investigation. At the same time different alternative treatments are pursued by many patients, despite the paucity of supporting, comparable, replicated scientific study.This article focuses on therapies for standard MS; borderline forms of MS have particular treatments that are excluded.