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The effect of montelukast on respiratory infants
The effect of montelukast on respiratory infants

... has been found to improve inflammatory biomarkers [21]. However, when compared with low-dose ICS treatment, it has consistently been less effective in children aged .2 yrs [22]. The excellent safety profile, oral administration route, oncedaily dosing and, possibly, better adherence to treatment are ...
Extract from the Clinical Evaluation Report for Nepafenac
Extract from the Clinical Evaluation Report for Nepafenac

... Shake the bottle well before use. After cap is removed, if tamper evident snap collar is loose, remove before using Ilevro. If more than one topical ophthalmic medicinal product is being used, the medicinal products must be administered at least 5 minutes apart. Eye ointments should be administered ...
Product Monograph Template - Standard
Product Monograph Template - Standard

... In myopic CNV, a clinical trial was conducted in Japan, South Korea, Singapore, Taiwan and Hong Kong. Thus there is no clinical trial experience with EYLEA in the treatment of non-Asian patients for this indication. Furthermore, there is also no clinical trial experience in patients who have previo ...
Czech mass methanol outbreak 2012: Epidemiology, challenges
Czech mass methanol outbreak 2012: Epidemiology, challenges

... Objectives. Methanol poisonings occur frequently globally, but reports of larger outbreaks where complete clinical and laboratory data are reported remain scarce. The objective of the present study was to report the data from the mass methanol poisoning in the Czech Republic in 2012 addressing the g ...
Guidelines for the management of tinea capitis
Guidelines for the management of tinea capitis

... quality of evidence ˆ III.) Soaking off crust from kerions or pustules. This is recommend by some authors. Although this is not necessary, it is often soothing.29 (Strength of recommendation ˆ C; quality of evidence III.) Steroids. The use of corticosteroids (both oral and topical) for inflammatory ...
Current Approaches to Asthma Management
Current Approaches to Asthma Management

... our current understanding of asthma, it is apparent that our pathology colleagues were closer to the truth. A series of experiments beginning in the 1970s changed our view of asthma. Researchers developed techniques for performing bronchoalveolar lavage and bronchial biopsies in patients with mild a ...
vertigo
vertigo

National Antiretroviral Treatment Guidelines
National Antiretroviral Treatment Guidelines

... ■ Efavirenz (EFV) 600 mg at night (or 400 mg if <40 kg) OR nevirapine (NVP) 200 mg daily for the first 2 weeks, increasing to 200 mg every 12 hours after this. N.B. ...
Comparison of three auto-adjusting positive pressure devices in patients with sleep apnoea
Comparison of three auto-adjusting positive pressure devices in patients with sleep apnoea

... as well as the improvement in symptoms, is similar to that of fixed-pressure CPAP therapy [11–13]. At present, there is insufficient evidence of benefits of APAP devices over traditional CPAP treatment to justify their routine use in clinical practice [14]. The role of APAP in increasing patient com ...
Sjögren`s syndrome - International Painful Bladder Foundation
Sjögren`s syndrome - International Painful Bladder Foundation

... found in every cell and play a role in the division of cells. Although it is not certain whether these antibodies can cause disease symptoms in Sjögren's patients, they may possibly increase the skin's sensitivity to sunlight. When women with these antibodies are pregnant, the antibodies also reach ...
Acute intraoperative brain herniation during elective
Acute intraoperative brain herniation during elective

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Pharmacologic Treatment Of Vestibular Disorders INTRODUCTION
Pharmacologic Treatment Of Vestibular Disorders INTRODUCTION

... outside the U.S. The oral agents are only used for mild nausea, with sublingual administration preferable for outpatients. When an oral agent is appropriate, meclizine or dimenhidrinate (Dramamine®), antihistamines commonly used also as vestibular suppressants, are generally the first to be used bec ...
Gastroesophageal reflux disease: exaggerations, evidence
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... Data synthesis: abdominal ultrasonography should not be recommended to investigate gastroesophageal reflux (GER). Simultaneous treatment of GERD and CMPA often results in unnecessary use of medication or elimination diet. There is insufficient evidence for the prescription of prokinetics to all patien ...
Interstitial Lung Disease Induced by Drugs and Radiation
Interstitial Lung Disease Induced by Drugs and Radiation

... patients with pulmonary fibrosis. Where possible, corticosteroid therapy should not be given to selectively evaluate the effect of drug dechallenge. Recurrence with rechallenge is central to the diagnosis of druginduced ILD. This carries intrinsic risks, as pulmonary reactions of increased severity ...
Interstitial Lung Disease Induced by Drugs and Radiation Thematic Review Series
Interstitial Lung Disease Induced by Drugs and Radiation Thematic Review Series

... patients with pulmonary fibrosis. Where possible, corticosteroid therapy should not be given to selectively evaluate the effect of drug dechallenge. Recurrence with rechallenge is central to the diagnosis of druginduced ILD. This carries intrinsic risks, as pulmonary reactions of increased severity ...
understanding ulcerative colitis
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... moderate to severe disease. They are also used to prevent or reduce corticosteroid dependence in inflammatory bowel disease. Immunosuppressants control inflammation by blocking the immune reaction and therefore maintain disease remission. They are administered orally. As immunosuppressants are slow ...
INFORMATION - World Health Organization
INFORMATION - World Health Organization

... of known pathogens and their resistance to antimicrobials can change rapidly. The history of HIV infection shows that where diagnostic facilities are lacking, a new disease can strike and take an increasing toll of death for years without recognition. The retrovirus, of course, would have eluded bas ...
AIDS and Ophthalmology: The First Quarter Century
AIDS and Ophthalmology: The First Quarter Century

... microvasculopathy also results in retinal and optic nerve damage, manifested by thinning of the retina and loss of axons in the optic nerve.19,20 These changes may be the cause for an increased prevalence of various vision abnormalities (abnormal color vision, reduced contrast sensitivity, and visua ...
Draft Measures - Home | American Academy of Neurology
Draft Measures - Home | American Academy of Neurology

... Purpose of Measurement Set In 2014, the American Academy of Neurology (AAN) formed a multi-disciplinary Multiple Sclerosis Work Group (Work Group) to review existing guidelines and evidence, gaps in care and to develop a measurement set for multiple sclerosis (MS) to promote quality improvement and ...
Full text
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... for oxygen concentrators, liquid oxygen units and oxygen cylinders (to be referred to as “oxygen concentrators, etc.” in the following) used for Long-term Oxygen Therapy (LTOT) contain WARNINGs stating, for example, “Do not use the equipment close to fire (burn injury and fire may occur)” to alert u ...
January - June 2016 - Amrita Institute of Medical Sciences
January - June 2016 - Amrita Institute of Medical Sciences

... of chemotherapy. A residue of less than 3cm with normal markers post surgery may be followed up. Although literature is scarce in this regard, we have some data to suggest that survival of patients with immature teratoma who underwent secondary cytoreductive surgery is superior compared to those wit ...
PDF Edition - Retina
PDF Edition - Retina

... Regardless of your detailed, diagram-assisted discussions, this question and its derivatives frequently resurface. “Doc, you said three shots, right?” Wrong, at least for more than 90 percent of wet age-related macular degeneration patients. Many of us tell patients that wet AMD is like hypertension ...
Scottish sample, follow-up outcomes
Scottish sample, follow-up outcomes

... patients not followed-up all showed no improvement or otherwise had poor outcomes. ...
EM Critical Care - SLR EM Education
EM Critical Care - SLR EM Education

... The treatment of a patient who has sustained an overdose of a beta blocker and/or calcium channel-blocking agent can be challenging and time-sensitive, with few proven treatment options beyond supportive care. Such cases present relatively infrequently in the spectrum of emergency medicine and criti ...
Vertigo - Webstercare
Vertigo - Webstercare

... movements) may also be present. Ménière’s disease is a recurrent vertigo accompanied by ringing in the ears (tinnitus) and deafness. Episodes usually last for hours and are accompanied by auditory symptoms. Symptoms of Ménière’s disease include vertigo, dizziness, nausea, vomiting, loss of hearing ( ...
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Management of multiple sclerosis



Several therapies for multiple sclerosis (MS) exist, although there is no known cure. Multiple sclerosis is a chronic inflammatory demyelinating disease that affects the central nervous system (CNS).The most common initial course of the disease is the relapsing-remitting subtype, which is characterized by unpredictable attacks (relapses) followed by periods of relative remission with no new signs of disease activity. After some years, many of the people who have this subtype begin to experience neurologic decline without acute relapses. When this happens it is called secondary progressive multiple sclerosis. Other, less common, courses of the disease are the primary progressive (decline from the beginning without attacks) and the progressive-relapsing (steady neurologic decline and superimposed attacks). Different therapies are used for patients experiencing acute attacks, for patients who have the relapsing-remitting subtype, for patients who have the progressive subtypes, for patients without a diagnosis of MS who have a demyelinating event, and for managing the various consequences of MS.The primary aims of therapy are returning function after an attack, preventing new attacks, and preventing disability. As with any medical treatment, medications used in the management of MS may have several adverse effects, and many possible therapies are still under investigation. At the same time different alternative treatments are pursued by many patients, despite the paucity of supporting, comparable, replicated scientific study.This article focuses on therapies for standard MS; borderline forms of MS have particular treatments that are excluded.
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