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General Information Brochure on orthostatic
General Information Brochure on orthostatic

... because a high salt diet in some individuals with high or high-normal blood pressure can lead to further increases in blood pressure, and thereby contribute to heart disease and stroke. This has led to general health recommendations to “cut down on salt.” As we are finding, this general recommendati ...
Evidence for the Use of Levodopa–Carbidopa–Entacapone
Evidence for the Use of Levodopa–Carbidopa–Entacapone

... good tolerability of levodopa–carbidopa–entacapone makes its choice pertinent in the management of such complications. Levodopa– carbidopa–entacapone provides an option that does not require the addition of a drug with neurological effects, since the action of entacapone is exclusively at a peripher ...
Re-use of Explanted DDD Pacemakers as VDD
Re-use of Explanted DDD Pacemakers as VDD

... related to ethical and legal problems associated with this approach. The ethical and legal issues involve both the retrieval of a still usable pacemaker from a deceased patient and the selection of the patient to receive such a pacemaker. In countries such as Sweden, pacemakers are considered to be ...
The role of intra-articular hyaluronan (Sinovial) in the treatment
The role of intra-articular hyaluronan (Sinovial) in the treatment

... OA. The optimal management of OA of the knee requires a combination of nonpharmacological and pharmacological treatment modalities. Treatment should be tailored according to: knee risk factors (obesity, adverse mechanical factors, physical activity); general risk factors (age, comorbidity, polypharm ...
general information brochure on orthostatic
general information brochure on orthostatic

... or fainting, most people feel tired for several hours (sometimes more than a day) and their thinking can be somewhat foggy. Some patients with NMH or POTS experience prolonged fatigue after a modest amount of physical activity, or after sustaining quiet activity like sitting at a desk. This fatigue ...
The Cruelest Cure? Ethical Issues in the Implementation
The Cruelest Cure? Ethical Issues in the Implementation

... had heard of any legal action or ethics complaints specifically regarding exposure. It should be noted that a survey approach to obtaining data about ethical and legal issues is not without obvious limitations. Unknown, for example, is whether such complaints have been filed but dismissed or settled ...
Costing statement: Ulcerative colitis
Costing statement: Ulcerative colitis

... The manufacturer suggests that there could be a reduction in the number of drug-related adverse events compared with other biologic drugs. Based on the estimates in the manufacturer’s submission, there could be 189 less adverse events such as skin reactions and serious infections. With a weighted av ...
Chronic Recurrent Multifocal Osteomyelitis of the Spine
Chronic Recurrent Multifocal Osteomyelitis of the Spine

... phagocytic cells, neutrophil chemotaxis, or phagocytosis. There was no association with HLA-B27, antinuclear antibody, or rheumatoid factor.2,6,19 There have been no controlled trials evaluating or comparing different drug therapies or surgical interventions. With the relapsing-remitting course of C ...
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Health_Psychology_Paper_pdf
Health_Psychology_Paper_pdf

... patient surveys report sizeable negative responses to CBT and associated therapies. In a 2015 ME Association survey (n=1428), of those patients who had CBT alone, only 8% reported CBT improving symptoms, while 73% reported no improvement, and 18% reported symptom deterioration. While unsolicited pat ...
HALDOL Injection
HALDOL Injection

... Extrapyramidal reactions such as Parkinson-like symptoms, akathisia or dystonic reactions occur frequently with antipsychotics including oral and injectable haloperidol. These have been observed with HALDOL Decanoate. In most patients, Parkinson-like symptoms, when first observed, were usually mild ...
STRATA Skin Sciences (SSKN)
STRATA Skin Sciences (SSKN)

... and vitiligo, the two indications most commonly treated with XTRAC. The device is indicated for all levels of psoriasis, mild, moderate, and severe. Several clinical trials have established the utility of excimer laser therapy for psoriasis. Patients typically achieve 75% to 90% disease clearance af ...
(PSD) March 2015 PBAC Meeting
(PSD) March 2015 PBAC Meeting

... Lymphoma disease after their ASCT autologous stem cell transplant. Applications for authorisation of initial treatment must be in writing and must include: (a) a completed authority prescription form; and (b) a completed Hodgkin lymphoma Brentuximab vedotin PBS Authority Application Supporting Infor ...
Chemotherapy and your nails and swelling. Skin infections (paronychia) around
Chemotherapy and your nails and swelling. Skin infections (paronychia) around

a v a i l a b l e a... j o u r n a l h o m...
a v a i l a b l e a... j o u r n a l h o m...

Aims - EQUIP
Aims - EQUIP

... 1. This guidance is based on the best available evidence but its application must be modified by professional judgement. 2. A dose and duration of treatment is suggested. In severe or recurrent cases consider a larger dose or longer course 3. Prescribe an antibiotic only when there is likely to be a ...
RAZADYNE ER/RAZADYNE Prescribing Information
RAZADYNE ER/RAZADYNE Prescribing Information

... types of heart block have been reported in patients both with and without known underlying cardiac conduction abnormalities [see Adverse Reactions (6.1, 6.2)]. Therefore, all patients should be considered at risk for adverse effects on cardiac conduction. Patients treated with galantamine up to 24 m ...
suggestions for a high sodium diet
suggestions for a high sodium diet

... or fainting, most people feel tired for several hours (sometimes more than a day) and their thinking can be somewhat foggy. Some patients with NMH or POTS experience prolonged fatigue after a modest amount of physical activity, or after sustaining quiet activity like sitting at a desk. This fatigue ...
Ocular surface disease incidence in patients with open
Ocular surface disease incidence in patients with open

... Classification of dry eye toward the pathogenesis includes I. tear hyperosmolarity, and II. tear film instability. Hyperosmolarity (>300 mOsm/l) is essential in pathogenesis in all types of dry eye. Tear film instability in any of the three layers (lipid, aqueous, and mucous) is the key factor, and ...
New Biologic Drugs: Evaluation and Treatment of Hypersensitivity
New Biologic Drugs: Evaluation and Treatment of Hypersensitivity

... AAAAI Drug Allergy Practice Parameters 2010 ...
Hereditary Angioedema (HAE) Physician’s Guide
Hereditary Angioedema (HAE) Physician’s Guide

Pr ILARIS - Ask Novartis Pharma
Pr ILARIS - Ask Novartis Pharma

... year old age group vs. 2.7% in adult CAPS patients. The severe phenotype and disease severity in young children may have played a role in this difference. Isolated cases of unusual or opportunistic infections (including aspergillosis, atypical mycobacterial infections, herpes zoster) have been repor ...
60 - Pericarditis, Pericardial Tamponade, and Myocarditis
60 - Pericarditis, Pericardial Tamponade, and Myocarditis

... are effectively treated with high-dose aspirin (2 to 4 g daily) or nonsteroidal antiinflammatory drugs (NSAIDs). Ibuprofen is effective in most cases and has fewer side effects than other NSAIDs; the pain usually improves significantly within days with ibuprofen therapy. If the patient’s symptoms pe ...
ulcerative colitis
ulcerative colitis

... due to tuberculosis, typhoid fever, or malignant disease. The origin remained obscure, however, and he felt this condition should not be confused with bacillary dysentery.2 Since these first descriptions, are there now data supporting a non-bacterial origin of the disease as suggested, or have we fo ...
clear and brilliant consent - The American Board of Laser Surgery
clear and brilliant consent - The American Board of Laser Surgery

... Clear + Brilliant Pre-Op Information What is Clear + Brilliant? Clear and Brilliant is a unique treatment that uses safe fractional laser technology to address early signs of aging skin and help to prevent them. How does Clear + Brilliant work? Clear + Brilliant is a gentle laser that refreshes your ...
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Management of multiple sclerosis



Several therapies for multiple sclerosis (MS) exist, although there is no known cure. Multiple sclerosis is a chronic inflammatory demyelinating disease that affects the central nervous system (CNS).The most common initial course of the disease is the relapsing-remitting subtype, which is characterized by unpredictable attacks (relapses) followed by periods of relative remission with no new signs of disease activity. After some years, many of the people who have this subtype begin to experience neurologic decline without acute relapses. When this happens it is called secondary progressive multiple sclerosis. Other, less common, courses of the disease are the primary progressive (decline from the beginning without attacks) and the progressive-relapsing (steady neurologic decline and superimposed attacks). Different therapies are used for patients experiencing acute attacks, for patients who have the relapsing-remitting subtype, for patients who have the progressive subtypes, for patients without a diagnosis of MS who have a demyelinating event, and for managing the various consequences of MS.The primary aims of therapy are returning function after an attack, preventing new attacks, and preventing disability. As with any medical treatment, medications used in the management of MS may have several adverse effects, and many possible therapies are still under investigation. At the same time different alternative treatments are pursued by many patients, despite the paucity of supporting, comparable, replicated scientific study.This article focuses on therapies for standard MS; borderline forms of MS have particular treatments that are excluded.
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