CNS Neurotransmitters
... • Major role is in the spinal cord • Glycine receptor is an ionotropic chloride channel analagous to the GABAA receptor. • Strychnine, a competitive antagonist of glycine, removes spinal inhibition to skeletal muscle and induces a violent motor response. ...
... • Major role is in the spinal cord • Glycine receptor is an ionotropic chloride channel analagous to the GABAA receptor. • Strychnine, a competitive antagonist of glycine, removes spinal inhibition to skeletal muscle and induces a violent motor response. ...
Uppers, Downers, All Arounders: I. Current Trends in
... • All Arounders (Psychedelics) distort and interfere with brain perceptions to produce delusions, illusion, hallucinations, & synesthesia (DXM=‘Robo’ to ‘paka-lolo’ to Sylvia d) ...
... • All Arounders (Psychedelics) distort and interfere with brain perceptions to produce delusions, illusion, hallucinations, & synesthesia (DXM=‘Robo’ to ‘paka-lolo’ to Sylvia d) ...
Pharm Test 2 - Glory Cubed Productions
... They work almost instantaneously because of the enormous surface area of the bronchioles and alveoli and the rich blood supply to them. 1. Aerosol – suspension of minute liquid droplets or fine solid particles suspended in a gas for an immediate onset of action. 2. Nebulizer – small machine that vap ...
... They work almost instantaneously because of the enormous surface area of the bronchioles and alveoli and the rich blood supply to them. 1. Aerosol – suspension of minute liquid droplets or fine solid particles suspended in a gas for an immediate onset of action. 2. Nebulizer – small machine that vap ...
No Slide Title - Open.Michigan
... • Benzodiazepines (BDZ) bind to GABAA receptors and enhance the action of GABA • BDZs are useful for a wide variety of indications but have limited CNS depressant activity • Principles important in onset and half-life of BDZs are lipophilicity, redistribution and metabolism • Unwanted effects includ ...
... • Benzodiazepines (BDZ) bind to GABAA receptors and enhance the action of GABA • BDZs are useful for a wide variety of indications but have limited CNS depressant activity • Principles important in onset and half-life of BDZs are lipophilicity, redistribution and metabolism • Unwanted effects includ ...
Drug-abuse poisoning: new substances in the 21st
... Symptoms sought by the consumer are euphoria, wellbeing, relaxation, drowsiness, impaired time perception and increased appetite, but are highly variable depending on the dose adsorbed (Table 1). Cannabis use is associated with an increased risk of cardiovascular disease, neurovascular disease or PA ...
... Symptoms sought by the consumer are euphoria, wellbeing, relaxation, drowsiness, impaired time perception and increased appetite, but are highly variable depending on the dose adsorbed (Table 1). Cannabis use is associated with an increased risk of cardiovascular disease, neurovascular disease or PA ...
Pharmacokinetiks and Pharmacodynamics
... The amount and rate of absorption are determined by several factors: Physical nature of the dosage form Presence or absence of food in the stomach Composition of the GI contents Gastric or intestinal pH Mesenteric blood flow Concurrent administration with other drugs ...
... The amount and rate of absorption are determined by several factors: Physical nature of the dosage form Presence or absence of food in the stomach Composition of the GI contents Gastric or intestinal pH Mesenteric blood flow Concurrent administration with other drugs ...
Sedative Hypnotics
... Note: Rohypnal is illegal in the United States and is considered to be one of the most addictive of the benzodiazepines. It is 10 times more powerful than valium. ...
... Note: Rohypnal is illegal in the United States and is considered to be one of the most addictive of the benzodiazepines. It is 10 times more powerful than valium. ...
Novel psychoactive substances of interest for psychiatry
... 5-MeO-DMT; N,N-diethyltryptamine, DET; 5-(2-aminopropyl)indole, 5-IT) continue to appear on the online drug scenario (2,82,100,101). Most exogenous tryptamines are psychoactive hallucinogens found naturally (102-106), notably in Delosperma species plants (dimethyltryptamine, DMT; 5-MeO-DMT), halluci ...
... 5-MeO-DMT; N,N-diethyltryptamine, DET; 5-(2-aminopropyl)indole, 5-IT) continue to appear on the online drug scenario (2,82,100,101). Most exogenous tryptamines are psychoactive hallucinogens found naturally (102-106), notably in Delosperma species plants (dimethyltryptamine, DMT; 5-MeO-DMT), halluci ...
Carlsson et al (2000)
... dopamine receptors ) and M100907 (blocks 5HT serotonin receptors) to see which is best able to overcome amphetamine-induced hyperactivity Haloperidol was more effective They then brought about hyperactivity by lowering glutamate levels with MK-801 (NMDA blocker) This time the serotonin blocker was m ...
... dopamine receptors ) and M100907 (blocks 5HT serotonin receptors) to see which is best able to overcome amphetamine-induced hyperactivity Haloperidol was more effective They then brought about hyperactivity by lowering glutamate levels with MK-801 (NMDA blocker) This time the serotonin blocker was m ...
Drugs and Alcohol
... called neurotransmitters. Neurotransmitters are able to work by attaching to key sites on neurons called receptors. One of the neurotransmitters affected by cocaine is called dopamine. Dopamine is released by neurons in the limbic system—the part of the brain that controls feelings of pleasure. Norm ...
... called neurotransmitters. Neurotransmitters are able to work by attaching to key sites on neurons called receptors. One of the neurotransmitters affected by cocaine is called dopamine. Dopamine is released by neurons in the limbic system—the part of the brain that controls feelings of pleasure. Norm ...
week3am
... 2. G-protein coupled receptors ◦ (metabotropic) ◦ 2nd messenger systems ◦ more than 50 G protein coupled receptors have been identified (large and diverse family) ◦ control many cellular processes ◦ Involved in synaptic effects of many nt ...
... 2. G-protein coupled receptors ◦ (metabotropic) ◦ 2nd messenger systems ◦ more than 50 G protein coupled receptors have been identified (large and diverse family) ◦ control many cellular processes ◦ Involved in synaptic effects of many nt ...
Power Point for Katherine van Wormer and Diane Rae Davis
... • Parkinson’s when too little. Dopamine-boosting drugs for Parkinson’s associated with mania and gambling behavior. • Too much dopamine associated with schizophrenia • Serotonin: influenced by alcohol, involved in sleep. Decreased levels linked to depression, anxiety, impulsiveness suicide. ...
... • Parkinson’s when too little. Dopamine-boosting drugs for Parkinson’s associated with mania and gambling behavior. • Too much dopamine associated with schizophrenia • Serotonin: influenced by alcohol, involved in sleep. Decreased levels linked to depression, anxiety, impulsiveness suicide. ...
Effects of Three Reversal Agents on Detomidine- Induced
... Detomidinea gel is well absorbed and elicits many of the same cardiac and behavioral changes observed with the parental formulations. Antagonism of central nervous system and cardiovascular effects by ␣2 antagonists after parenteral administration of detomidine have been well characterized. The goal ...
... Detomidinea gel is well absorbed and elicits many of the same cardiac and behavioral changes observed with the parental formulations. Antagonism of central nervous system and cardiovascular effects by ␣2 antagonists after parenteral administration of detomidine have been well characterized. The goal ...
Why is Pharma So Scared of Psychiatric Drug Discovery?
... Keywords: Drug discovery, Pharmaceutical industry, Molecular drug targets, Opioids Accepted on May 03, 2017 ...
... Keywords: Drug discovery, Pharmaceutical industry, Molecular drug targets, Opioids Accepted on May 03, 2017 ...
ADDERALL (the study drug)
... May cause existing mental illness's to worsen and possible psychosis; 10 or 11 recent cases Most were on adderall for longer than 3 years ...
... May cause existing mental illness's to worsen and possible psychosis; 10 or 11 recent cases Most were on adderall for longer than 3 years ...
Al Tmimi - Cardiovascular active medications tekst
... tachycardia and decrease in peripheral resistance, made Isuprel as a poor inotropic of choice. Isuprel used mostly in cases of bradycardia not responding to atropine or in cases of 3rd degree AV block until a pacemaker can be placed. Isuprel also decrease the pulmonary vascular resistance through st ...
... tachycardia and decrease in peripheral resistance, made Isuprel as a poor inotropic of choice. Isuprel used mostly in cases of bradycardia not responding to atropine or in cases of 3rd degree AV block until a pacemaker can be placed. Isuprel also decrease the pulmonary vascular resistance through st ...
Methamphetamine
... Short term effects • Stimulant • Hyperthermia, inflammation of the heart lining, risk of heart attack and stroke ...
... Short term effects • Stimulant • Hyperthermia, inflammation of the heart lining, risk of heart attack and stroke ...
Cultural, Legal, and Ethical Considerations
... DEA will monitor the number of controlled substance prescriptions a consumer is using and from what physicians the prescriptions are being dispensed. ...
... DEA will monitor the number of controlled substance prescriptions a consumer is using and from what physicians the prescriptions are being dispensed. ...
Psychopharmacology
Psychopharmacology (from Greek ψῡχή, psȳkhē, ""breath, life, soul""; φάρμακον, pharmakon, ""drug""; and -λογία, -logia) is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior.The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain.Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as ""drug action"", and the widespread changes in physiological or psychological function is referred to as ""drug effect"". These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory.